Simon Topp

9.2k citations

29 papers · 861 indexed · h-index 15

Impact in

Neurology top 5%
- Amyotrophic Lateral Sclerosis Research
- Parkinson's Disease Mechanisms and Treatments
- Neurological diseases and metabolism
Genetics top 5%
- Neurogenetic and Muscular Disorders Research

Papers in ⓘ

Neurology 15
- Amyotrophic Lateral Sclerosis Research 15
- Parkinson's Disease Mechanisms and Treatments 6
- Neurological diseases and metabolism 5
Genetics 10
- Neurogenetic and Muscular Disorders Research 10

Co-authors: Daniel M. Spielman (1 shared paper)Albert Macovski (1 shared paper)Elfar Adalsteinsson (1 shared paper)Pablo Irarrázabal (1 shared paper)Craig H. Meyer (1 shared paper)Christopher E. Shaw (13 shared papers)Bradley Smith (11 shared papers)Sverre Rosenbaum (2 shared papers)
Journals: Neurobiology of Aging (6 papers)Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (3 papers)Journal of Cerebral Blood Flow & Metabolism (2 papers)Magnetic Resonance Imaging (2 papers)Acta Neuropathologica Communications (1 paper)
Partner nations: United Kingdom Denmark United States

In The Last Decade

Simon Topp

29 papers receiving 850 citations

Peers

Countries citing papers authored by Simon Topp

Since Specialization

Citations

This map shows the geographic impact of Simon Topp's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon Topp with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon Topp more than expected).

Fields of papers citing papers by Simon Topp

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon Topp. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon Topp. The network helps show where Simon Topp may publish in the future.

Co-authors

The 25 scholars most cited alongside Simon Topp, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon Topp Line = papers co-authored together Simon Topp links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 29 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Volumetric spectroscopic imaging with spiral‐based k‐space trajectories Magnetic Resonance in Medicine ·Elfar Adalsteinsson, Pablo Irarrázabal, Simon Topp, Craig H. Meyer, Albert Macovski, Daniel M. Spielman	1998	165
2	Quantification of brain metabolites in amyotrophic lateral sclerosis by localized proton magnetic resonance spectroscopy Neurology ·Ole Gredal, Sverre Rosenbaum, Simon Topp, Merete Karlsborg, P Strange, Lene Werdelin	1997	84
3	Novel mutations support a role for Profilin 1 in the pathogenesis of ALS Neurobiology of Aging ·Bradley Smith, Caroline Vance, Emma L. Scotter, Claire Troakes, Chun Hao Wong, Simon Topp, Satomi Maekawa, Andrew King, Jacqueline C. Mitchell, Karan Lund, Ammar Al‐Chalabi, Nicola Ticozzi, Vincenzo Silani, Peter C. Sapp, Robert H. Brown, John E. Landers, Safa Al‐Sarraj, Christopher E. Shaw	2014	81
4	The role of positive selection in determining the molecular cause of species differences in disease BMC Evolutionary Biology ·Jessica Vamathevan, Samiul Hasan, Richard D. Emes, Heather Amrine‐Madsen, Dilip Rajagopalan, Simon Topp, Vinod Kumar, Michael Word, Mark D Simmons, Steven M. Foord, Philippe Sanséau, Ziheng Yang, Joanna D. Holbrook	2008	75
5	RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy Brain ·Han-Jou Chen, Simon Topp, Ho Sang Hui, Elsa Zacco, Malvika Katarya, C. McLoughlin, Andrew King, Bradley Smith, Claire Troakes, Annalisa Pastore, Christopher E. Shaw	2019	68
6	Evaluation of CA1 damage using single-voxel 1H-MRS and un-biased stereology: Can non-invasive measures of N-acetyl-asparate following global ischemia be used as a reliable measure of neuronal damage? Brain Research ·Thomas N. Sager, Simon Topp, Lars Torup, Lars G. Hanson, Börje Egestad, Arne Møller	2001	49
7	Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD Acta Neuropathologica Communications ·Michael Niblock, Bradley Smith, Youn‐Bok Lee, Valentina Sardone, Simon Topp, Claire Troakes, Safa Al‐Sarraj, Claire S. Leblond, Patrick A. Dion, Guy A. Rouleau, Christopher E. Shaw, Jean‐Marc Gallo	2016	45
8	Characterisation of gene expression changes following permanent MCAO in the rat using subtractive hybridisation Molecular Brain Research ·Stewart Bates, Simon Read, David C. Harrison, Simon Topp, Rachel Morrow, Davina Gale, Paul R. Murdock, Frank C. Barone, Andrew A. Parsons, Israel Gloger	2001	37
9	N-Acetylaspartate Distribution in Rat Brain Striatum During Acute Brain Ischemia Journal of Cerebral Blood Flow & Metabolism ·Thomas Nikolaj Sager, Henning Laursen, Anders Fink‐Jensen, Simon Topp, Anders Stensgaard, Maj Hedehus, Sverre Rosenbaum, Jacob S. Valsborg, Anker Jón Hansen	1999	34
10	Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias Journal of Neurology Neurosurgery & Psychiatry ·Puja R. Mehta, Ashley Jones, Sarah Opie-Martin, Aleksey Shatunov, Alfredo Iacoangeli, Ahmad Al Khleifat, Bradley Smith, Simon Topp, Karen Morrison, Pamela J. Shaw, Christopher E. Shaw, Sarah Morgan, Alan Pittman, Ammar Al‐Chalabi	2018	29
11	Deep sequencing of theLRRK2gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe Human Mutation ·Justin P. Rubio, Simon Topp, Liling Warren, Pamela L. St. Jean, Daniel Wegmann, Darren Kessner, John Novembre, Judong Shen, Dana J. Fraser, Jennifer L. Aponte, Keith Nangle, Lon R. Cardon, Margaret G. Ehm, Stephanie L. Chissoe, John C. Whittaker, Matthew R. Nelson, Vincent Mooser	2012	24
12	Global Cerebral Blood Flow and Metabolism during Acute Hyperketonemia in the Awake and Anesthetized Rat Journal of Cerebral Blood Flow & Metabolism ·Rasmus Linde, Steen Gregers Hasselbalch, Simon Topp, Olaf B. Paulson, Peter Lund Madsen	2005	22
13	Mutation analysis of VCP in British familial and sporadic amyotrophic lateral sclerosis patients Neurobiology of Aging ·Jack W. Miller, Bradley Smith, Simon Topp, Ammar Al‐Chalabi, Christopher E. Shaw, Caroline Vance	2012	16
14	Screening for OPTN mutations in a cohort of British amyotrophic lateral sclerosis patients Neurobiology of Aging ·Lauren Johnson, Jack W. Miller, Soragia Athina Gkazi, Caroline Vance, Simon Topp, Stephen Newhouse, Ammar Al‐Chalabi, Bradley Smith, Christopher E. Shaw	2012	16
15	Striking phenotypic variation in a family with the P506S UBQLN2 mutation including amyotrophic lateral sclerosis, spastic paraplegia, and frontotemporal dementia Neurobiology of Aging ·Soragia Athina Gkazi, Claire Troakes, Simon Topp, Jack W. Miller, Caroline Vance, Jemeen Sreedharan, Ammar Al‐Chalabi, Janine Kirby, Pamela J. Shaw, Safa Al‐Sarraj, Andrew King, Bradley Smith, Christopher E. Shaw	2018	15
16	The CHCHD10 P34S variant is not associated with ALS in a UK cohort of familial and sporadic patients Neurobiology of Aging ·Chun Hao Wong, Simon Topp, Soragia Athina Gkazi, Claire Troakes, Jack W. Miller, Martina de Majo, Janine Kirby, Pamela J. Shaw, Karen Morrison, Jacqueline de Belleroche, Caroline Vance, Ammar Al‐Chalabi, Safa Al‐Sarraj, Christopher E. Shaw, Bradley Smith	2015	14
17	Are Grammatical Representations Useful for Learning from Biological Sequence Data?— A Case Study Journal of Computational Biology ·Stephen Muggleton, Christopher H. Bryant, Ashwin Srinivasan, A. Whittaker, Simon Topp, Chris Rawlings	2001	13
18	Autosomal dominant inheritance of rapidly progressive amyotrophic lateral sclerosis due to a truncation mutation in the fused in sarcoma (FUS) gene Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration ·Louisa Kent, Thomas N. Vizard, Bradley Smith, Simon Topp, Caroline Vance, Soragia Athina Gkazi, Jack W. Miller, Christopher E. Shaw, Kevin Talbot	2014	13
19	Absolute metabolite quantification by in vivo NMR spectroscopy: III. multicentre 1H MRS of the human brain addressed by one and the same data-analysis protocol Magnetic Resonance Imaging ·Randall D. Beer, Bruno Barbiroli, G. Gobbi, Arnold Knijn, H. Kg̋el, Karl Langenberger, (unknown), Simon Topp	1998	11
20	New Methods for Researching Accessory Proteins Journal of Molecular Neuroscience ·Steven M. Foord, Simon Topp, Marco Abramo, Joanna D. Holbrook	2005	10

About Simon Topp

Simon Topp is a scholar working on Neurology, Genetics, Neurology, Biophysics and Clinical Biochemistry, having authored 29 papers that have together received 861 indexed citations. Recurring topics across this work include Amyotrophic Lateral Sclerosis Research (15 papers), Neurogenetic and Muscular Disorders Research (10 papers), Parkinson's Disease Mechanisms and Treatments (6 papers), Advanced MRI Techniques and Applications (6 papers), Neurological diseases and metabolism (5 papers), Metabolism and Genetic Disorders (2 papers), Metabolomics and Mass Spectrometry Studies (2 papers) and Genetic Neurodegenerative Diseases (2 papers). The work is most often cited by research in Neurology (360 citations), Genetics (184 citations), Neurology (106 citations), Radiology, Nuclear Medicine and Imaging (242 citations) and Cellular and Molecular Neuroscience (134 citations). Simon Topp has collaborated with scholars based in United Kingdom, Denmark and United States. Frequent co-authors include Daniel M. Spielman, Albert Macovski, Elfar Adalsteinsson, Pablo Irarrázabal, Craig H. Meyer, Christopher E. Shaw, Bradley Smith, Sverre Rosenbaum, Claire Troakes and Merete Karlsborg. Their work appears in journals such as Neurobiology of Aging, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Journal of Cerebral Blood Flow & Metabolism, Magnetic Resonance Imaging and Acta Neuropathologica Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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