Nathan R. Rose

5.6k citations

32 papers · 4.1k indexed · 1 hit paper · h-index 25

Molecular Biology top 2%
Cancer Research top 2%
Genetics top 5%
Oncology top 10%
Genetics top 5%

Co-authors: Robert J. Klose Christopher J. Schofield M.A. McDonough Oliver N. F. King Akane Kawamura Neil P. Blackledge Udo Oppermann Stanley S. Ng
Topics: Epigenetics and DNA Methylation (23 papers)Histone Deacetylase Inhibitors Research (13 papers)Cancer-related gene regulation (13 papers)
Cited by: Cancer Research Molecular Biology Genetics
Journals: Nature Chemical Society Reviews Journal of Biological Chemistry
Partner nations: United Kingdom United States Singapore

In The Last Decade

Nathan R. Rose

32 papers receiving 4.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

2011 762 citations Rasheduzzaman Chowdhury, Kar Kheng Yeoh et al. EMBO Reports profile →

Peers

Countries citing papers authored by Nathan R. Rose

Since Specialization

Citations

This map shows the geographic impact of Nathan R. Rose's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nathan R. Rose with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nathan R. Rose more than expected).

Fields of papers citing papers by Nathan R. Rose

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nathan R. Rose. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nathan R. Rose. The network helps show where Nathan R. Rose may publish in the future.

Co-authorship network of co-authors of Nathan R. Rose

This figure shows the co-authorship network connecting the top 25 collaborators of Nathan R. Rose. A scholar is included among the top collaborators of Nathan R. Rose based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nathan R. Rose. Nathan R. Rose is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Biochemical Identification of Nonmethylated DNA by BioCAP-Seq 2018 ·Methods in molecular biology ·Hannah K. Long,Nathan R. Rose,Neil P. Blackledge,Robert J. Klose	1
2	Studies on the Glutathione-Dependent Formaldehyde-Activating Enzyme from Paracoccus denitrificans 2015 ·PLoS ONE ·Richard J. Hopkinson,Ivanhoe K. H. Leung,(unknown),Nathan R. Rose,Luc Henry,Timothy D. W. Claridge,Christopher J. Schofield	10
3	Targeting Polycomb systems to regulate gene expression: modifications to a complex story 2015 ·Nature Reviews Molecular Cell Biology ·Neil P. Blackledge,Nathan R. Rose,Robert J. Klose	266
4	Is JmjC Oxygenase Catalysis Limited to Demethylation? 2013 ·Angewandte Chemie ·Richard J. Hopkinson,Louise J. Walport,Martin Münzel,Nathan R. Rose,(unknown),Akane Kawamura,Timothy D. W. Claridge,Christopher J. Schofield	4
5	Is JmjC Oxygenase Catalysis Limited to Demethylation? 2013 ·Angewandte Chemie International Edition ·Richard J. Hopkinson,Louise J. Walport,Martin Münzel,Nathan R. Rose,(unknown),Akane Kawamura,Timothy D. W. Claridge,Christopher J. Schofield	34
6	Discovery of ML324, a JMJD2 demethylase inhibitor with demonstrated antiviral activity 2013 ·Ganesha Rai,Akane Kawamura,Anthony Tumber,Yu Liang,Jodi L. Vogel,Jesse H. Arbuckle,Nathan R. Rose,Thomas S. Dexheimer,Timothy L. Foley,Oliver N. F. King,Amy Quinn,Bryan T. Mott,Christopher J. Schofield,Udo Oppermann,Ajit Jadhav,Anton Simeonov,Thomas M. Kristie,David J. Maloney	25
7	Linking of 2‐Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases 2012 ·Angewandte Chemie International Edition ·Esther C. Y. Woon,Anthony Tumber,Akane Kawamura,Lars Hillringhaus,Wei Ge,Nathan R. Rose,(unknown),Mun Chiang Chan,Louise J. Walport,Ka Hing,Stanley S. Ng,Brian D. Marsden,Udo Oppermann,M.A. McDonough,Christopher J. Schofield	55
8	Inhibition of Histone Demethylases by 4‐Carboxy‐2,2′‐Bipyridyl Compounds 2011 ·ChemMedChem ·Kai‐Hsuan Chang,Oliver N. F. King,Anthony Tumber,Esther C. Y. Woon,Tom D. Heightman,M.A. McDonough,Christopher J. Schofield,Nathan R. Rose	61
9	Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family 2011 ·Journal of Biological Chemistry ·Lars Hillringhaus,Wyatt W. Yue,Nathan R. Rose,Stanley S. Ng,C. Gileadi,Christoph Loenarz,(unknown),James E. Bray,Christopher J. Schofield,Udo Oppermann	140
10	The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylasesbreakdown → 2011 ·EMBO Reports ·Rasheduzzaman Chowdhury,Kar Kheng Yeoh,Ya‐Min Tian,Lars Hillringhaus,Eleanor A. L. Bagg,Nathan R. Rose,Ivanhoe K. H. Leung,(unknown),Esther C. Y. Woon,Ming Yang,M.A. McDonough,Oliver N. F. King,I.J. Clifton,Robert J. Klose,Timothy D. W. Claridge,Peter J. Ratcliffe,Christopher J. Schofield,Akane Kawamura	762
11	Inhibition of 2-oxoglutarate dependent oxygenases 2011 ·Chemical Society Reviews ·Nathan R. Rose,M.A. McDonough,Oliver N. F. King,Akane Kawamura,Christopher J. Schofield	304
12	Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates 2010 ·Organic & Biomolecular Chemistry ·Armin Thalhammer,Jasmin Mecinović,Christoph Loenarz,Anthony Tumber,Nathan R. Rose,Tom D. Heightman,Christopher J. Schofield	48
13	Development of homogeneous luminescence assays for histone demethylase catalysis and binding 2010 ·Analytical Biochemistry ·Akane Kawamura,Anthony Tumber,Nathan R. Rose,Oliver N. F. King,(unknown),Udo Oppermann,Tom D. Heightman,Christopher J. Schofield	51
14	Monitoring the Activity of 2‐Oxoglutarate Dependent Histone Demethylases by NMR Spectroscopy: Direct Observation of Formaldehyde 2010 ·ChemBioChem ·Richard J. Hopkinson,Refaat B. Hamed,Nathan R. Rose,Timothy D. W. Claridge,Christopher J. Schofield	53
15	Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors 2010 ·PLoS ONE ·Oliver N. F. King,(unknown),Masaaki Sakurai,Akane Kawamura,Nathan R. Rose,Stanley S. Ng,Amy Quinn,Ganesha Rai,Bryan T. Mott,Paul Beswick,Robert J. Klose,Udo Oppermann,Ajit Jadhav,Tom D. Heightman,David J. Maloney,Christopher J. Schofield,Anton Simeonov	173
16	2-Oxoglutarate oxygenases are inhibited by a range of transition metals 2010 ·Metallomics ·Rok Sekirnik,Nathan R. Rose,Jasmin Mecinović,Christopher J. Schofield	28
17	A miniaturized screen for inhibitors of Jumonji histonedemethylases 2009 ·Molecular BioSystems ·Masaaki Sakurai,Nathan R. Rose,Lena Schultz,Amy Quinn,Ajit Jadhav,Stanley S. Ng,Udo Oppermann,Christopher J. Schofield,Anton Simeonov	76
18	Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(ii) 2009 ·Chemical Communications ·Rok Sekirnik,Nathan R. Rose,Armin Thalhammer,Peter Seden,Jasmin Mecinović,Christopher J. Schofield	72
19	PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase 2009 ·Human Molecular Genetics ·Christoph Loenarz,Wei Ge,Mathew L. Coleman,Nathan R. Rose,C.D.O. Cooper,Robert J. Klose,Peter J. Ratcliffe,Christopher J. Schofield	136
20	Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity 2007 ·Nature ·Stanley S. Ng,K.L. Kavanagh,M.A. McDonough,Danica Butler,Ewa S. Pilka,Benoît M. R. Liénard,James E. Bray,P. Savitsky,O. Gileadi,F. von Delft,Nathan R. Rose,John Offer,Johanna C. Scheinost,Tomasz Borowski,M. Sundström,Christopher J. Schofield,Udo Oppermann	263

About Nathan R. Rose

Nathan R. Rose is a scholar working on Molecular Biology, Cancer Research and Biochemistry, having authored 32 papers that have together received 4.1k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (23 papers), Histone Deacetylase Inhibitors Research (13 papers) and Cancer-related gene regulation (13 papers). The work is most often cited by research in Cancer Research (863 citations), Molecular Biology (3.5k citations) and Genetics (237 citations). Nathan R. Rose has collaborated with scholars based in United Kingdom, United States and Singapore. Frequent co-authors include Robert J. Klose, Christopher J. Schofield, M.A. McDonough, Oliver N. F. King, Akane Kawamura, Neil P. Blackledge, Udo Oppermann, Stanley S. Ng, Esther C. Y. Woon and Peter J. Ratcliffe. Their work appears in journals such as Nature, Chemical Society Reviews and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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