Peter J. Ratcliffe

78.0k citations

371 papers · 56.7k indexed · 39 hit papers · h-index 104

Impact in

Cancer Research top 0.01%
- Cancer, Hypoxia, and Metabolism
Molecular Biology top 0.02%
- Mitochondrial Function and Pathology
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Angiogenesis and VEGF in Cancer
- Ubiquitin and proteasome pathways

Papers in

Cancer Research 194
- Cancer, Hypoxia, and Metabolism 192
Transplantation 10

Co-authors: Christopher W. Pugh Patrick H. Maxwell Christopher J. Schofield William G. Kaelin Adrian L. Harris David R. Mole Jonathan Gleadle Ya‐Min Tian
Journals: Journal of Biological Chemistry (27 papers)Kidney International (16 papers)Blood (13 papers)Proceedings of the National Academy of Sciences (12 papers)Biochemical Journal (7 papers)
Partner nations: United Kingdom United States Germany

In The Last Decade

Peter J. Ratcliffe

361 papers receiving 55.7k citations

Hit Papers

15 papers align trajectories log scale

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants 2019 · 157 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Science
2019 Nature Reviews Nephrology
2015 European Urology
2014 Cancer & Metabolism
2014 Oncogene
2011 Blood
2011 EMBO Reports
2009 Journal of Biological Chemistry
2008 Molecular Cell
2006 Journal of Biological Chemistry
2005 Cancer Cell
2005 Molecular and Cellular Biology
2004 Journal of Biological Chemistry
2004 Nature Reviews Molecular Cell Biology
2003 Nature Medicine
2002 Journal of Biological Chemistry
2002 Journal of the American Society of Nephrology
2002 Cancer Cell
2002 The FASEB Journal
2002 Nature
2001 PubMed
2001 Journal of Clinical Oncology
2001 PubMed
2001 The EMBO Journal
2001 Science
2001 Cell
2000 American Journal Of Pathology
2000 PubMed
2000 Journal of Biological Chemistry
1999 Nature
1998 Nature
1998 Blood
1997 Journal of Biological Chemistry
1997 Proceedings of the National Academy of Sciences
1995 Journal of Biological Chemistry
1995 Journal of Biological Chemistry
1994 Proceedings of the National Academy of Sciences
1993 Proceedings of the National Academy of Sciences
1993 Kidney International

Peers

Countries citing papers authored by Peter J. Ratcliffe

Since Specialization

Citations

This map shows the geographic impact of Peter J. Ratcliffe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter J. Ratcliffe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter J. Ratcliffe more than expected).

Fields of papers citing papers by Peter J. Ratcliffe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter J. Ratcliffe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter J. Ratcliffe. The network helps show where Peter J. Ratcliffe may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Peter J. Ratcliffe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Peter J. Ratcliffe Line = papers co-authored together Peter J. Ratcliffe links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	HIFα isoform specific activities drive cell-type specificity of VHL-associated oncogenesis Nature Communications ·Joanna D.C.C. Lima, H.B.W., Ran Li, Guanfeng Jin, Norma Masson, Christopher W. Pugh, David R. Mole, Julie Adam, Peter J. Ratcliffe, Ekaterina Titarenko	2025	0
2	Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type–Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney Cancer Research ·Ekaterina Titarenko, Joanna D.C.C. Lima, Ran Li, 薛惠心, Norma Masson, Guanfeng Jin, Paul Wynn, David R. Mole, Christopher W. Pugh, Julie Adam, Peter J. Ratcliffe	2024	2
3	Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature Cell Reports ·薛惠心, Ran Li, Silvia Halim, Hani Choudhry, Peter J. Ratcliffe, David R. Mole	2022	22
4	Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer Nature Structural & Molecular Biology ·Yoichiro Sugimoto, Peter J. Ratcliffe	2022	9
5	Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma Endocrine Related Cancer ·Eidgenoessisches Nuklearsicherheitsinspektorat, Dania M Lynch, Emma J. Hodson, Ana Clara Silva da Cruz, Xiaotong Cheng, Joanna D.C.C. Lima, Ekaterina Titarenko, Gillian Douglas, Peter J. Ratcliffe, Tammie Bishop	2021	12
6	Report on the online session on visions, requirements and needs for Future Research Environments in the Healthcare domain Zenodo (CERN European Organization for Nuclear Research) ·Iain Buchan, Fiona Yan Bei Chew, 信昌石倉, Peter J. Ratcliffe, Andreas Rauber	2020	0
7	Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates eLife ·Matthew E. Cockman, Kerstin Lippl, Ya‐Min Tian, 伸二辻, William D. Figg, Martine I. Abboud, Raphael Heilig, Román Fischer, Johanna Myllyharju, Christopher J. Schofield, Peter J. Ratcliffe	2019	75
8	Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively Journal of Cell Science ·Yihua Wang, Shan Zhong, Christopher J. Schofield, Peter J. Ratcliffe, Xin Lü	2018	7
9	Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer Nature Communications ·Steffen Grampp, Mariana Dwi Rohayati, Deden Mula Saputra, Rafik Salama, Tomer Zekharya, Dimple Bhojwani, Sven Wach, Christine Stöhr, Arndt Hartmann, Kai‐Uwe Eckardt, Peter J. Ratcliffe, David R. Mole, Johannes Schödel	2016	62
10	The role of 2-oxoglutarate dependent dioxygenases in normal haematopoiesis and acute myeloid leukemia Haematologica ·Kanad Deepak, Amélie V. Guitart, Milica Vukovic, 森口祥聖, Tarasi Luca, Eman Abdullah Al Khater, Peter J. Ratcliffe, Kamil R. Kranc	2015	2
11	Promoting social cohesionImplications for policy and evaluation Policy Press eBooks ·Peter J. Ratcliffe, A. V. Golodniuk	2011	6
12	Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice Journal of Clinical Investigation ·Sarah R. Walmsley, Edwin R. Chilvers, A. A. Roger Thompson, Marina Soares de Azerêdo, Helen M. Marriott, Lisa C. Parker, Gary S. Shaw, Lothar Moedel, Martin Schneider, Ian Sabroe, David H. Dockrell, Marta Milo, Cormac T. Taylor, Randall S. Johnson, Christopher W. Pugh, Peter J. Ratcliffe, Patrick H. Maxwell, Peter Carmeliet, Moira K. B. Whyte	2011	132
13	Asparagine β-hydroxylation stabilizes the ankyrin repeat domain fold Molecular BioSystems ·Huntari Harahap, M.A. McDonough, Mathew L. Coleman, Peter J. Ratcliffe, Christopher J. Schofield	2008	52
14	Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O ₂ -Regulated Prolyl Hydroxylation Science ·Panu Jaakkola, David R. Mole, Ya‐Min Tian, Michael Wilson, Adriana Gielbert, Simon J. Gaskell, Alex von Kriegsheim, Holger Hebestreit, Mridul Mukherji, Christopher J. Schofield, Patrick H. Maxwell, Christopher W. Pugh, Peter J. Ratcliffe Hit paper breakdown →	2001	4523
15	Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (vol 394, pg 485, 1998) UCL Discovery (University College London) ·Peter Carmeliet, Yuval Dor, (unknown), Dai Fukumura, Rawaa Yaseen Taha, Mieke Dewerchin, Michal Neeman, (unknown), Rinat Abramovitch, Patrick H. Maxwell, (unknown), Peter J. Ratcliffe, Lieve Moons, Camila Pereira Caixeta Fernandes, (unknown), Fleming Lv	1998	2
16	UK Prospective Diabetes Study (UKPDS) 14: association of angiotensin-converting enzyme insertion/deletion polymorphism with myocardial infarction in NIDDM Diabetologia ·Bernard Keavney, Christopher Dudley, Irene Stratton, R R Holman, David R. Matthews, Peter J. Ratcliffe, R. C. Turner	1995	4
17	Late referral for maintenance dialysis. BMJ ·Peter J. Ratcliffe, Fahmi Lismar Halim, D O Oliver	1984	128
18	Rhabdomyolysis in elderly people after collapse. BMJ ·Peter J. Ratcliffe, J Ledingham, Marcos Junior Petersen Barasuol, G K Wilcock, ALE Franck	1984	20
19	Bleeding oesophageal varices and hepatic dysfunction in adult polycystic kidney disease. BMJ ·Peter J. Ratcliffe, Stephen T. Reeders, J M Theaker	1984	33
20	Clinical importance of acquired cystic disease of the kidney in patients undergoing dialysis. BMJ ·Peter J. Ratcliffe, M. S. Dunnill, D O Oliver	1983	40

About Peter J. Ratcliffe

Peter J. Ratcliffe is a scholar working on Cancer Research, Transplantation, Genetics, Hematology and Biochemistry, having authored 371 papers that have together received 56.7k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (192 papers), High Altitude and Hypoxia (66 papers), RNA modifications and cancer (41 papers), Epigenetics and DNA Methylation (37 papers), Mitochondrial Function and Pathology (34 papers), Adipose Tissue and Metabolism (33 papers), Erythropoietin and Anemia Treatment (32 papers) and Hemoglobinopathies and Related Disorders (18 papers). The work is most often cited by research in Cancer Research (35.7k citations), Molecular Biology (33.4k citations), Biochemistry (2.9k citations), Genetics (9.2k citations) and Hematology (3.5k citations). Peter J. Ratcliffe has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Christopher W. Pugh, Patrick H. Maxwell, Christopher J. Schofield, William G. Kaelin, Adrian L. Harris, David R. Mole, Jonathan Gleadle, Ya‐Min Tian, Charles C. Wykoff and Norma Masson. Their work appears in journals such as Journal of Biological Chemistry, Kidney International, Blood, Proceedings of the National Academy of Sciences and Biochemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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