Brian D. Marsden

12.3k citations

65 papers · 3.9k indexed · 1 hit paper · h-index 30

Impact in

Molecular Biology top 2%
- Protein Degradation and Inhibitors
- Protein Structure and Dynamics
- Ubiquitin and proteasome pathways
- Histone Deacetylase Inhibitors Research
Hematology top 5%
- Multiple Myeloma Research and Treatments

Papers in

Computational Theory and Mathematics 12
- Computational Drug Discovery Methods 12
Molecular Biology 48
- Protein Structure and Dynamics 17
- Protein Degradation and Inhibitors 10
- Ubiquitin and proteasome pathways 6
- Histone Deacetylase Inhibitors Research 5

Co-authors: Stefan Knapp O. Fedorov Alex N. Bullock M. Sundström F. von Delft O. Gileadi James E. Bray C.D.O. Cooper
Journals: Bioinformatics (6 papers)Journal of Medicinal Chemistry (4 papers)Journal of Chemical Information and Modeling (4 papers)Journal of Biological Chemistry (3 papers)Proceedings of the National Academy of Sciences (3 papers)
Partner nations: United Kingdom United States Canada

In The Last Decade

Brian D. Marsden

64 papers receiving 3.8k citations

Hit Papers

align trajectories log scale

Second malignant neoplasms in children: an update from the Late Effects Study Group. 1985 · 377 citations

Peers

Countries citing papers authored by Brian D. Marsden

Since Specialization

Citations

This map shows the geographic impact of Brian D. Marsden's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian D. Marsden with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian D. Marsden more than expected).

Fields of papers citing papers by Brian D. Marsden

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian D. Marsden. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian D. Marsden. The network helps show where Brian D. Marsden may publish in the future.

Co-authors

The 25 scholars most cited alongside Brian D. Marsden, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brian D. Marsden Line = papers co-authored together Brian D. Marsden links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology Journal of Cheminformatics ·Matteo P. Ferla, Rubén Sánchez-García, R. Skyner, Stefan Gahbauer, Jenny C. Taylor, F. von Delft, Brian D. Marsden, Charlotte M. Deane	2025	3
2	Robustly interrogating machine learning-based scoring functions: what are they learning? Bioinformatics ·G. J. DURANT, Fergus Boyles, Kristian Birchall, Brian D. Marsden, Charlotte M. Deane	2025	8
3	Integrative GWAS and co-localisation analysis suggests novel genes associated with age-related multimorbidity Scientific Data ·Clare E. West, Mohd Anisul Karim, Maria J. Falaguera, Leo Speidel, Charlotte Green, Lisa Logie, Jeremy Schwartzentruber, David Ochoa, Janet M. Lord, Michael A. J. Ferguson, C. Bountra, Graeme Wilkinson, Beverley Vaughan, Andrew R. Leach, Ian Dunham, Brian D. Marsden	2023	3
4	FAS2FURIOUS: Moderate-Throughput Secreted Expression of Difficult Recombinant Proteins in Drosophila S2 Cells Frontiers in Bioengineering and Biotechnology ·Jesse A. Coker, V.L. Katis, M. Fairhead, Anja Schwenzer, Stine B. Clemmensen, Bent U. Frandsen, Willem A. de Jongh, O. Gileadi, N. Burgess-Brown, Brian D. Marsden, Kim S. Midwood, Wyatt W. Yue	2022	1
5	Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections BMC Infectious Diseases ·David W. Eyre, Sheila Lumley, Denise O’Donnell, Nicole Stoesser, Philippa C. Matthews, Alison Howarth, Stephanie B. Hatch, Brian D. Marsden, Stuart Cox, Tim James, Richard J. Cornall, David I. Stuart, Gavin Screaton, Daniel Ebner, Derrick W. Crook, Christopher P. Conlon, Katie Jeffery, A Sarah Walker, Tim Peto	2021	19
6	An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains Angewandte Chemie International Edition ·Melissa D’Ascenzio, Kathryn Pugh, Rebecca Konietzny, G. Berridge, C. Tallant, Shaima Hashem, Octovia Monteiro, Jason R. Thomas, Markus Schirle, Stefan Knapp, Brian D. Marsden, Oleg Fedorov, C. Bountra, Benedikt M. Kessler, Paul E. Brennan	2018	19
7	WONKAandOOMMPPAA: analysis of protein–ligand interaction data to direct structure-based drug design Acta Crystallographica Section D Structural Biology ·Charlotte M. Deane, Ian D. Wall, Darren V. S. Green, Brian D. Marsden, A.R. Bradley	2017	5
8	WONKA: objective novel complex analysis for ensembles of protein–ligand structures Journal of Computer-Aided Molecular Design ·A.R. Bradley, Ian D. Wall, F. von Delft, Darren V. S. Green, Charlotte M. Deane, Brian D. Marsden	2015	7
9	Linking genotypes database with locus-specific database and genotype–phenotype correlation in phenylketonuria European Journal of Human Genetics ·Sarah Wettstein, Jarl Underhaug, Belén Pérez, Brian D. Marsden, Wyatt W. Yue, Aurora Martı́nez, Nenad Blau	2014	65
10	High-throughput production of human proteins for crystallization: The SGC experience Journal of Structural Biology ·P. Savitsky, James E. Bray, C.D.O. Cooper, Brian D. Marsden, P. Mahajan, N. Burgess-Brown, O. Gileadi	2010	241
11	A New Method for Publishing Three-Dimensional Content PLoS ONE ·Eugene Raush, Maxim Totrov, Brian D. Marsden, Ruben Abagyan	2009	35
12	The human short-chain dehydrogenase/reductase (SDR) superfamily: A bioinformatics summary Chemico-Biological Interactions ·James E. Bray, Brian D. Marsden, Udo Oppermann	2008	81
13	Doing more than just the structure—structural genomics in kinase drug discovery Current Opinion in Chemical Biology ·Brian D. Marsden, Stefan Knapp	2008	27
14	Insights for the development of specific kinase inhibitors by targeted structural genomics Drug Discovery Today ·O. Fedorov, M. Sundström, Brian D. Marsden, Stefan Knapp	2007	36
15	Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination Proceedings of the National Academy of Sciences ·Masoud Vedadi, F. Niesen, Abdellah Allali‐Hassani, O. Fedorov, P.J. Finerty, Gregory A. Wasney, Ron Yeung, C.H. Arrowsmith, Linda Ball, H. Berglund, Raymond Hui, Brian D. Marsden, P. Nordlund, M. Sundström, Johan Weigelt, A.M. Edwards	2006	471
16	High-throughput structural characterisation of therapeutic protein targets Expert Opinion on Drug Discovery ·Brian D. Marsden, M. Sundström, Stefan Knapp	2006	1
17	Gas Phase Characterization of the Noncovalent Quaternary Structure of Cholera Toxin and the Cholera Toxin B Subunit Pentamer Biophysical Journal ·Jonathan P. Williams, Daniel C. Smith, Brian N. Green, Brian D. Marsden, Keith R. Jennings, Lynne M. Roberts, James H. Scrivens	2006	5
18	A Novel Allelic Variant of the Human TSG-6 Gene Encoding an Amino Acid Difference in the CUB Module Journal of Biological Chemistry ·Hilke A. Nentwich, Zehra Mustafa, Marilyn S. Rugg, Brian D. Marsden, Martin R. Cordell, David J. Mahoney, Suzanne Jenkins, B L Dowling, Erik Fries, Caroline M. Milner, John Loughlin, Anthony J. Day	2002	51
19	The treatment of Wilms' tumour: results of the United Kingdom Children's Cancer Study Group (UKCCSG) second Wilms' tumour study British Journal of Cancer ·Christopher Mitchell, P. Morris Jones, Anna Kelsey, Gordan Vujanić, Brian D. Marsden, R S Shannon, P. Gornall, Cátherine M. Owens, Roger Taylor, John Imeson, Hayden T. Middleton, Jon Pritchard	2000	90
20	Novalike Object in Vulpecula International Astronomical Union Circular ·S. Mochnacki, M. Schmidt, Reese Green, Kosei Ishida, Yuichi Yamashita, Kyoji Nariai, Tohru Noguchi, Yuji Norimoto, Y. Kuwano, Brian D. Marsden	1979	1

About Brian D. Marsden

Brian D. Marsden is a scholar working on Computational Theory and Mathematics, Molecular Biology, Hematology, Immunology and Allergy and Oncology, having authored 65 papers that have together received 3.9k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (17 papers), Computational Drug Discovery Methods (12 papers), Enzyme Structure and Function (11 papers), Protein Degradation and Inhibitors (10 papers), Ubiquitin and proteasome pathways (6 papers), Microbial Natural Products and Biosynthesis (5 papers), Histone Deacetylase Inhibitors Research (5 papers) and Multiple Myeloma Research and Treatments (5 papers). The work is most often cited by research in Molecular Biology (2.7k citations), Hematology (318 citations), Computational Theory and Mathematics (375 citations), Oncology (642 citations) and Cell Biology (269 citations). Brian D. Marsden has collaborated with scholars based in United Kingdom, United States and Canada. Frequent co-authors include Stefan Knapp, O. Fedorov, Alex N. Bullock, M. Sundström, F. von Delft, O. Gileadi, James E. Bray, C.D.O. Cooper, T. Krojer and N. Burgess-Brown. Their work appears in journals such as Bioinformatics, Journal of Medicinal Chemistry, Journal of Chemical Information and Modeling, Journal of Biological Chemistry and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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