M.A. McDonough

12.5k citations

144 papers · 8.3k indexed · 1 hit paper · h-index 49

Impact in

Cancer Research top 0.5%
- Cancer, Hypoxia, and Metabolism
Molecular Medicine top 0.5%
- Antibiotic Resistance in Bacteria

Papers in

Molecular Medicine 19
- Antibiotic Resistance in Bacteria 19
Cancer Research 51
- Cancer, Hypoxia, and Metabolism 49

Co-authors: Christopher J. Schofield Rasheduzzaman Chowdhury I.J. Clifton Nathan R. Rose Peter J. Ratcliffe Kirsty S. Hewitson Christoph Loenarz Akane Kawamura
Journals: Journal of Biological Chemistry (9 papers)Journal of Medicinal Chemistry (8 papers)Proceedings of the National Academy of Sciences (7 papers)Angewandte Chemie International Edition (6 papers)Chemical Communications (4 papers)
Partner nations: United Kingdom United States Australia

In The Last Decade

M.A. McDonough

143 papers receiving 8.2k citations

Hit Papers

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The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases 2011 · 762 citations

Peers

Countries citing papers authored by M.A. McDonough

Since Specialization

Citations

This map shows the geographic impact of M.A. McDonough's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by M.A. McDonough with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites M.A. McDonough more than expected).

Fields of papers citing papers by M.A. McDonough

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by M.A. McDonough. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by M.A. McDonough. The network helps show where M.A. McDonough may publish in the future.

Co-authors

The 25 scholars most cited alongside M.A. McDonough, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with M.A. McDonough Line = papers co-authored together M.A. McDonough links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation ACS Chemical Biology ·Nurul Husnah, M. Teresa Serafini, Emma K. Grant, 無雨藤原, Mathieu Nony, Matthias Schiedel, M.A. McDonough, Sara Frasca, Isabel del Carmen Sáenz-Tavera, 孙欣, Idoia Arregi Castaños, Philip C. Biggin, Fernanda Duarte, Thomas A. Milne, Jacob T. Bush, Stuart J. Conway	2023	1
2	Small Molecule Ligands of the BET-like Bromodomain, Sm BRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development Journal of Medicinal Chemistry ·Matthias Schiedel, Audhatul Faidz, Gilda Padalino, Anthony Chan, Yang Hun Kim, M.A. McDonough, Helen Whiteland, Manfred Beckmann, С.В. Кубиевич, Karl F. Hoffmann, Stuart J. Conway	2023	2
3	Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2 Proteins Structure Function and Bioinformatics ·William D. Figg, V Ferreira Montero, Rasheduzzaman Chowdhury, Yu Nakashima, Anthony Tumber, M.A. McDonough, Christopher J. Schofield	2023	9
4	In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease Nature Chemistry ·Takashi Miura, Tika R. Malla, David Owen, Anthony Tumber, Lennart Brewitz, M.A. McDonough, E. Salah, Naohiro Terasaka, Takayuki Katoh, Petra Lukacik, Claire Strain‐Damerell, Halina Mikolajek, Martin Walsh, Akane Kawamura, Christopher J. Schofield, Hiroaki Suga	2023	36
5	An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides Nature Communications ·Ysobel R. Baker, Yuto Horikawa, Jinfeng Chen, Sergey Kharitonov, C Burns Robert, Pawan Kumar, Wooi Fang Lim, D.A. Nielsen, Graham McClorey, Chi-Jui Yang, J. A. Quiroga, M.A. McDonough, Késia dos Santos Costa, Kirsten E. Christensen, Matthew J. A. Wood, J.P. Hall, Afaf H. El‐Sagheer, Tom Brown	2022	27
6	Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5–RNA complexes Nucleic Acids Research ·Vetterling Jm, Peter Dalgleish, M.A. McDonough, Christopher J. Schofield, Wei Shen Aik	2022	54
7	Human Oxygenase Variants Employing a Single Protein Fe^II Ligand Are Catalytically Active Angewandte Chemie ·آناهیتا بیک زاده, Inga Pfeffer, Lennart Brewitz, Rasheduzzaman Chowdhury, Yu Nakashima, Anthony Tumber, M.A. McDonough, Christopher J. Schofield	2021	1
8	Human Oxygenase Variants Employing a Single Protein Fe^II Ligand Are Catalytically Active Angewandte Chemie International Edition ·آناهیتا بیک زاده, Inga Pfeffer, Lennart Brewitz, Rasheduzzaman Chowdhury, Yu Nakashima, Anthony Tumber, M.A. McDonough, Christopher J. Schofield	2021	15
9	Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity Proceedings of the National Academy of Sciences ·Mark D. White, 刘玉洁, 陈永跃, Sergio Iacopino, Martin P. Edwards, Taisa Honcharenko, Elisabete Pires, Colin Levy, M.A. McDonough, Francesco Licausi, Emily Flashman	2020	38
10	Anaerobic fixed-target serial crystallography IUCrJ ·Patrick Rabe, John H. Beale, Agata Butryn, Pierre Aller, Jun-qian Chang, Pauline A. Lang, Danny Axford, S.B. Carr, T.M. Leissing, M.A. McDonough, S. Shirotake, Ali Ebrahim, 達也平岡, H.K. Carter, Allen M. Orville, Christopher J. Schofield, Robin L. Owen	2020	17
11	Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii Journal of Biological Chemistry ·P Kraut, Martine I. Abboud, Rasheduzzaman Chowdhury, Anthony Tumber, A. Hardy, Kerstin Lippl, Christopher T. Lohans, Elisabete Pires, James R. Wickens, M.A. McDonough, Christopher M. West, Christopher J. Schofield	2020	13
12	Substrate Selectivity Analyses of Factor Inhibiting Hypoxia‐Inducible Factor Angewandte Chemie ·Ming Yang, A. Hardy, Rasheduzzaman Chowdhury, Nikita D. Loik, John S. Scotti, James McCullagh, Timothy D. W. Claridge, M.A. McDonough, Wei Ge, Christopher J. Schofield	2013	4
13	Structure of arylamineN-acetyltransferase fromM. tuberculosis: triumph over adversity Acta Crystallographica Section A Foundations of Crystallography ·Areej Abuhammad, E.D. Lowe, M.A. McDonough, Edith Sim, Elspeth F. Garman	2013	2
14	Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility Endocrine Related Cancer ·Dewi Astuti, Christopher J. Ricketts, Rasheduzzaman Chowdhury, M.A. McDonough, Dean Gentle, Gail Kirby, Susanne Schlisio, Rajappa S. Kenchappa, Tia Lombardi, William G. Kaelin, Peter J. Ratcliffe, Christopher J. Schofield, Farida Latif, Eamonn R. Maher	2010	48
15	Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases Structure ·Rasheduzzaman Chowdhury, M.A. McDonough, Jasmin Mecinović, Christoph Loenarz, Emily Flashman, Kirsty S. Hewitson, Cármen Domene, Christopher J. Schofield	2009	190
16	Asparagine β-hydroxylation stabilizes the ankyrin repeat domain fold Molecular BioSystems ·Huntari Harahap, M.A. McDonough, Mathew L. Coleman, Peter J. Ratcliffe, Christopher J. Schofield	2008	52
17	Acupuncture in Drug and Alcohol Withdrawal at the Community Residential Withdrawal Unit, Footscray Hospital, Melbourne M.A. McDonough, د خلود أحمد أمین حامد العبد, P. Belvisi, Kayte A. Jenkin, Damien Ryan	2008	1
18	Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2) Proceedings of the National Academy of Sciences ·M.A. McDonough, Vivian Li, Emily Flashman, Rasheduzzaman Chowdhury, Christopher Mohr, Benoît M. R. Liénard, James Zondlo, Neil J. Oldham, I.J. Clifton, Jeffrey Lewis, Luke A. McNeill, Robert J. Kurzeja, Kirsty S. Hewitson, Evelyn Yang, Steven R. Jordan, Rashid Syed, Christopher J. Schofield	2006	295
19	Proteomic analysis of Lactobacillus casei under starvation adaptation eCite Digital Repository (University of Tasmania) ·Malik Altaf Hussain, Efemena Emily Opubor, M.A. McDonough, W. K. Taylor	2006	4
20	Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences ·Kirsty S. Hewitson, Claúdio Muianga, Richard W.D. Welford, M.A. McDonough, Christopher J. Schofield	2005	48

About M.A. McDonough

M.A. McDonough is a scholar working on Molecular Medicine, Cancer Research, Inorganic Chemistry, Molecular Biology and Biochemistry, having authored 144 papers that have together received 8.3k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (49 papers), Epigenetics and DNA Methylation (22 papers), Metal-Catalyzed Oxygenation Mechanisms (20 papers), Antibiotic Resistance in Bacteria (19 papers), RNA modifications and cancer (19 papers), Mitochondrial Function and Pathology (19 papers), Cancer-related gene regulation (12 papers) and Metabolomics and Mass Spectrometry Studies (11 papers). The work is most often cited by research in Cancer Research (2.9k citations), Molecular Medicine (847 citations), Molecular Biology (5.8k citations), Biochemistry (566 citations) and Inorganic Chemistry (863 citations). M.A. McDonough has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Christopher J. Schofield, Rasheduzzaman Chowdhury, I.J. Clifton, Nathan R. Rose, Peter J. Ratcliffe, Kirsty S. Hewitson, Christoph Loenarz, Akane Kawamura, Oliver N. F. King and Wei Shen Aik. Their work appears in journals such as Journal of Biological Chemistry, Journal of Medicinal Chemistry, Proceedings of the National Academy of Sciences, Angewandte Chemie International Edition and Chemical Communications.

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