Robert J. Klose

17.1k total citations · 8 hit papers
69 papers, 11.7k citations indexed

About

Robert J. Klose is a scholar working on Molecular Biology, Genetics and Plant Science. According to data from OpenAlex, Robert J. Klose has authored 69 papers receiving a total of 11.7k indexed citations (citations by other indexed papers that have themselves been cited), including 67 papers in Molecular Biology, 14 papers in Genetics and 4 papers in Plant Science. Recurrent topics in Robert J. Klose's work include Epigenetics and DNA Methylation (62 papers), Genomics and Chromatin Dynamics (44 papers) and Cancer-related gene regulation (23 papers). Robert J. Klose is often cited by papers focused on Epigenetics and DNA Methylation (62 papers), Genomics and Chromatin Dynamics (44 papers) and Cancer-related gene regulation (23 papers). Robert J. Klose collaborates with scholars based in United Kingdom, United States and Japan. Robert J. Klose's co-authors include Adrian Bird, Yi Zhang, Neil P. Blackledge, Nathan R. Rose, Eric M. Kallin, Hamish W. King, Paul Tempst, Hediye Erdjument‐Bromage, Hannah K. Long and Anca M. Farcas and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Robert J. Klose

68 papers receiving 11.5k citations

Hit Papers

Genomic DNA methylation: the mark and its mediators 2006 2026 2012 2019 2006 2006 2011 2007 2014 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Genomic DNA methylation: the mark and its mediators
    2006 1.8k citations Robert J. Klose, Adrian Bird Trends in Biochemical Sciences profile →
  2. JmjC-domain-containing proteins and histone demethylation
    2006 997 citations Robert J. Klose, Yi Zhang et al. profile →
  3. The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases
    2011 762 citations Nathan R. Rose, Robert J. Klose et al. profile →
  4. Regulation of histone methylation by demethylimination and demethylation
    2007 661 citations Robert J. Klose, Yi Zhang Nature Reviews Molecular Cell Biology profile →
  5. Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
    2014 553 citations Neil P. Blackledge, Anca M. Farcas et al. Cell profile →
  6. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
    2006 505 citations Robert J. Klose, Kenichi Yamane et al. profile →
  7. The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
    2007 336 citations Robert J. Klose, Qin Yan et al. Cell profile →
  8. The molecular principles of gene regulation by Polycomb repressive complexes
    2021 254 citations Neil P. Blackledge, Robert J. Klose Nature Reviews Molecular Cell Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Robert J. Klose United Kingdom 45 10.2k 2.2k 1.3k 896 488 69 11.7k
R. David Hawkins United States 28 8.9k 0.9× 2.0k 0.9× 984 0.8× 648 0.7× 585 1.2× 43 10.2k
Raphaël Margueron France 44 9.6k 0.9× 1.5k 0.7× 1.6k 1.2× 792 0.9× 625 1.3× 66 10.9k
Johnathan R. Whetstine United States 34 8.7k 0.8× 1.3k 0.6× 1.1k 0.9× 542 0.6× 442 0.9× 51 9.9k
Yujiang Geno Shi United States 43 11.1k 1.1× 1.8k 0.8× 1.9k 1.5× 486 0.5× 735 1.5× 73 12.4k
Henry H. Heng United States 60 7.0k 0.7× 2.9k 1.3× 1.7k 1.3× 973 1.1× 779 1.6× 202 11.8k
Robert Schneider Germany 53 12.7k 1.2× 2.1k 1.0× 931 0.7× 1.2k 1.3× 889 1.8× 91 14.5k
Zachary D. Smith United States 32 9.6k 0.9× 2.1k 0.9× 731 0.6× 421 0.5× 479 1.0× 63 11.0k
Matthew G. Guenther United States 23 10.9k 1.1× 1.7k 0.8× 1.7k 1.4× 400 0.4× 526 1.1× 32 12.3k
John M. Greally United States 53 6.8k 0.7× 2.3k 1.0× 1.0k 0.8× 579 0.6× 615 1.3× 196 9.1k
Marianne Frommer Australia 30 7.9k 0.8× 2.3k 1.1× 715 0.6× 896 1.0× 339 0.7× 57 9.5k

Countries citing papers authored by Robert J. Klose

Since Specialization
Citations

This map shows the geographic impact of Robert J. Klose's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert J. Klose with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert J. Klose more than expected).

Fields of papers citing papers by Robert J. Klose

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert J. Klose. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert J. Klose. The network helps show where Robert J. Klose may publish in the future.

Co-authorship network of co-authors of Robert J. Klose

This figure shows the co-authorship network connecting the top 25 collaborators of Robert J. Klose. A scholar is included among the top collaborators of Robert J. Klose based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert J. Klose. Robert J. Klose is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Hirasaki, Masataka, et al.. (2025). MGA directly recruits SETDB1/ATF7IP for histone H3K9me3 mark on meiosis-related genes in mouse embryonic stem cells. iScience. 28(8). 113059–113059. 1 indexed citations
2.
Nakagawa, Rinako, Miriam Llorian, Probir Chakravarty, et al.. (2024). Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation. Nature Communications. 15(1). 10516–10516. 4 indexed citations
3.
Kelley, Jessica R., Emilia Dimitrova, Hieu Nguyen, et al.. (2024). The PNUTS phosphatase complex controls transcription pause release. Molecular Cell. 84(24). 4843–4861.e8. 6 indexed citations
4.
Alcázar‐Fabra, María, Lourdes López-Onieva, Emilia Dimitrova, et al.. (2023). Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Nature Communications. 14(1). 180–180. 2 indexed citations
5.
Dimitrova, Emilia, Angelika Feldmann, Robin H. van der Weide, et al.. (2022). Distinct roles for CKM–Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction. Nature Structural & Molecular Biology. 29(10). 1000–1010. 14 indexed citations
6.
Kelley, Jessica R., et al.. (2020). Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1863(8). 194567–194567. 89 indexed citations
7.
Turberfield, Anne H., Takashi Kondo, Manabu Nakayama, et al.. (2019). KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity. Nucleic Acids Research. 47(17). 9005–9023. 25 indexed citations
8.
9.
Long, Hannah K., Nathan R. Rose, Neil P. Blackledge, & Robert J. Klose. (2018). Biochemical Identification of Nonmethylated DNA by BioCAP-Seq. Methods in molecular biology. 1766. 15–29. 1 indexed citations
10.
King, Hamish W., Nadezda A. Fursova, Neil P. Blackledge, & Robert J. Klose. (2018). Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes. Genome Research. 28(10). 1494–1507. 49 indexed citations
11.
Brown, David A., Vincenzo Di Cerbo, Angelika Feldmann, et al.. (2017). The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin. Cell Reports. 20(10). 2313–2327. 67 indexed citations
12.
Kerry, Jon, Laura Godfrey, Emmanouela Repapi, et al.. (2017). MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. Cell Reports. 18(2). 482–495. 51 indexed citations
13.
Klose, Robert J., Sarah Cooper, Anca M. Farcas, Neil P. Blackledge, & Neil Brockdorff. (2013). Chromatin Sampling—An Emerging Perspective on Targeting Polycomb Repressor Proteins. PLoS Genetics. 9(8). e1003717–e1003717. 97 indexed citations
14.
Blackledge, Neil P., Jinchuan Zhou, Michael Tolstorukov, et al.. (2010). CpG Islands Recruit a Histone H3 Lysine 36 Demethylase. Molecular Cell. 38(2). 179–190. 241 indexed citations
15.
Loenarz, Christoph, Wei Ge, Mathew L. Coleman, et al.. (2009). PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase. Human Molecular Genetics. 19(2). 217–222. 136 indexed citations
16.
Yamane, Kenichi, Keisuke Tateishi, Robert J. Klose, et al.. (2007). PLU-1 Is an H3K4 Demethylase Involved in Transcriptional Repression and Breast Cancer Cell Proliferation. Molecular Cell. 25(6). 801–812. 378 indexed citations
17.
Klose, Robert J. & Yi Zhang. (2007). Regulation of histone methylation by demethylimination and demethylation. Nature Reviews Molecular Cell Biology. 8(4). 307–318. 661 indexed citations breakdown →
18.
Klose, Robert J., Qin Yan, Zuzana Tóthová, et al.. (2007). The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase. Cell. 128(5). 889–900. 336 indexed citations breakdown →
19.
Klose, Robert J. & Adrian Bird. (2006). Genomic DNA methylation: the mark and its mediators. Trends in Biochemical Sciences. 31(2). 89–97. 1834 indexed citations breakdown →
20.
Klose, Robert J., Shireen A. Sarraf, Lars Schmiedeberg, et al.. (2005). DNA Binding Selectivity of MeCP2 Due to a Requirement for A/T Sequences Adjacent to Methyl-CpG. Molecular Cell. 19(5). 667–678. 262 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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