Mark Ammirati

2.5k citations

20 papers · 1.2k indexed · h-index 14

Impact in

Molecular Medicine top 5%
- Antibiotic Resistance in Bacteria
Structural Biology top 10%

Papers in

Structural Biology 1
Toxicology 1

Co-authors: Dennis E. Danley Matthew C. Griffor Xiayang Qiu Kieran F. Geoghegan Mahmoud N. Mansour Andrew P. Seddon Lise R. Hoth Virginia L. Rath
Journals: Bioorganic & Medicinal Chemistry Letters (4 papers)Nature Communications (2 papers)Journal of Medicinal Chemistry (2 papers)Advances in experimental medicine and biology (1 paper)Nature Structural & Molecular Biology (1 paper)
Partner nations: United States United Kingdom Germany

In The Last Decade

Mark Ammirati

20 papers receiving 1.2k citations

Peers

Countries citing papers authored by Mark Ammirati

Since Specialization

Citations

This map shows the geographic impact of Mark Ammirati's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark Ammirati with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark Ammirati more than expected).

Fields of papers citing papers by Mark Ammirati

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark Ammirati. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark Ammirati. The network helps show where Mark Ammirati may publish in the future.

Co-authors

The 25 scholars most cited alongside Mark Ammirati, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark Ammirati Line = papers co-authored together Mark Ammirati links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics Nucleic Acids Research ·Hallikainen Anja, Kevin W. Huynh, Mark Ammirati, Seungil Han, Ben Bolaños, Richard J. Chavez, Matthew D. Petroski, Benedikt Bosbach, David J. Shields, James T. Stivers	2022	8
2	Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins Nature Communications ·Somnath Mukherjee, Satchal K. Erramilli, Mark Ammirati, Frances Joan D. Alvarez, Kimberly F. Fennell, Michael D. Purdy, 阿部広喜, Mahshid Eltemasi, John S. Coukos, Yanyong Kang, Przemysław Dutka, Xiang Gao, Xiayang Qiu, Mark Yeager, H. Eric Xu, Seungil Han, Anthony A. Kossiakoff	2020	67
3	Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20 Nature Communications ·JG Mackenzie, Z.L. Johnson, Mark Ammirati, Ye Che, Matthew C. Griffor, Seungil Han, Huixian Wu	2020	69
4	2-Aminopyridine-Based Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Inhibitors: Assessment of Mechanism-Based Safety Journal of Medicinal Chemistry ·Robert L. Dow, Mark Ammirati, Scott W. Bagley, Samit K. Bhattacharya, Leonard Buckbinder, Christian Cortés‐Campos, Ayman El‐Kattan, Boulakroune Abderrahmane, Gary B. Freeman, Cristiano R. W. Guimarães, Shenping Liu, Mark Niosi, Athanasia Skoura, David A. Tess	2018	10
5	Insights into Mechanism of Glucokinase Activation Journal of Biological Chemistry ·Shenping Liu, Mark Ammirati, Xi Song, John D. Knafels, Jeff Zhang, S.E. Greasley, Jeffrey A. Pfefferkorn, Xiayang Qiu	2012	56
6	(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: A potent, selective, orally active dipeptidyl peptidase IV inhibitor Bioorganic & Medicinal Chemistry Letters ·Mark Ammirati, Kim Andrews, Annette Mann, Neven Grbac, Dennis E. Danley, Shawn D. Doran, Bernard Hulin, Shenping Liu, R. Kirk McPherson, Stephen Orena, Janice C. Parker, Jana Polívková, Xiayang Qiu, Matthias Drögsler, Judith L. Treadway, Maria A. VanVolkenburg, Norman E. Weir, David W. Piotrowski	2009	33
7	(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: Synthesis, in vitro, in vivo, and X-ray crystallographic characterization Bioorganic & Medicinal Chemistry Letters ·Stephen W. Wright, Mark Ammirati, Kim Andrews, Neven Grbac, Dennis E. Danley, Shawn D. Doran, Jay S. Lillquist, Shenping Liu, Lester D. McClure, R. Kirk McPherson, Sofia Seabra Gomes, Stephen Orena, Janice C. Parker, Benjamin N. Rocke, Walter C. Soeller, Matthias Drögsler, Judith L. Treadway, Maria A. VanVolkenburg, Tanmay Mohapatra, Eric Cox	2007	13
8	The 2.0 Å crystal structure of the ERα ligand‐binding domain complexed with lasofoxifene Protein Science ·F.F. Vajdos, Lise R. Hoth, Kieran F. Geoghegan, Samuel P. Simons, Peter K. LeMotte, Dennis E. Danley, Mark Ammirati, Jayvardhan Pandit	2007	46
9	Design and synthesis of potent amido- and benzyl-substituted cis-3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl DPP-IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Jeffrey W. Corbett, Kenneth J. DiRico, 서영수, Brian P. Boscoe, Shawn D. Doran, Annette Mann, Xiayang Qiu, Mark Ammirati, Maria A. VanVolkenburg, R. Kirk McPherson, Jeremy C. Parker, Eric Cox	2007	20
10	Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia Nature Structural & Molecular Biology ·David Cunningham, Dennis E. Danley, Kieran F. Geoghegan, Matthew C. Griffor, Thana A. Ahmed, Timothy A. Subashi, Alison H. Varghese, Mark Ammirati, Jeffrey S. Culp, Lise R. Hoth, Mahmoud N. Mansour, Katherine McGrath, Andrew P. Seddon, Shirish Shenolikar, K J Stutzman-Engwall, Ji-Wen Fu, Angelo Zullo, Xiayang Qiu	2007	365
11	cis-2,5-Dicyanopyrrolidine Inhibitors of Dipeptidyl Peptidase IV: Synthesis and in Vitro, in Vivo, and X-ray Crystallographic Characterization Journal of Medicinal Chemistry ·Stephen W. Wright, Mark Ammirati, Kim Andrews, Neven Grbac, Dennis E. Danley, Shawn D. Doran, Jay S. Lillquist, Lester D. McClure, R. Kirk McPherson, Stephen Orena, Janice C. Parker, Jana Polívková, Xiayang Qiu, Walter C. Soeller, Matthias Drögsler, Judith L. Treadway, Maria A. VanVolkenburg, Hong Wang, Norman E. Weir, Sofia Seabra Gomes	2006	28
12	Specificity Determinants of Human Cathepsin S Revealed by Crystal Structures of Complexes^, Biochemistry ·Thomas Pauly, Traian Sulea, Mark Ammirati, J. Sivaraman, Dennis E. Danley, Matthew C. Griffor, Ajith V. Kamath, Franz Hammerl, Ellen R. Laird, Andrew P. Seddon, Robert Ménard, Mirosław Cygler, Virginia L. Rath	2003	70
13	Activation of Human Liver Glycogen Phosphorylase by Alteration of the Secondary Structure and Packing of the Catalytic Core Molecular Cell ·Virginia L. Rath, Mark Ammirati, Peter K. LeMotte, Kimberly F. Fennell, Mahmoud N. Mansour, Dennis E. Danley, Thomas R. Hynes, Gayle K. Schulte, David J. Wasilko, Jayvardhan Pandit	2000	80
14	Human liver glycogen phosphorylase inhibitors bind at a new allosteric site Chemistry & Biology ·Virginia L. Rath, Mark Ammirati, Dennis E. Danley, J.L. Ekstrom, E. Michael Gibbs, Thomas R. Hynes, Alan M. Mathiowetz, R. Kirk McPherson, Sofia Seabra Gomes, Judith L. Treadway, Dennis J. Hoover	2000	109
15	Glycylcyclines bind to the high-affinity tetracycline ribosomal binding site and evade Tet(M)- and Tet(O)-mediated ribosomal protection Antimicrobial Agents and Chemotherapy ·Jay Bergeron, Mark Ammirati, Dennis E. Danley, L James, Hartley Rogersi, James A. Retsema, Christine A. Strick, W.-G. Su, Joyce A. Sutcliffe, L Wondrack	1996	112
16	Rational design, synthesis, and X-ray structure of renin inhibitors with extended P1 sidechains Bioorganic & Medicinal Chemistry Letters ·Bruce A. Lefker, K. Yaghmaei, S. S. Lee, William H. Martin, Ingrid A. Stock, Gayle K. Schulte, Julio Roberto González Rios, Dennis E. Danley, Mark Ammirati, Scott Sneddon	1995	7
17	X-ray analyses of peptide–inhibitor complexes define the structural basis of specificity for human and mouse renins Nature ·V. Dhanaraj, Chris Dealwis, Carlos Frazão, M. Badasso, B. L. Sibanda, Ian J. Tickle, J.B. Cooper, H.P.C. Driessen, Matthew Newman, C. F. Aguilar, S. P. Wood, Tom L. Blundell, Peter Hobart, Kieran F. Geoghegan, Mark Ammirati, Dennis E. Danley, Diana Barrow, Dennis J. Hoover	1992	102
18	Crystallization and preliminary X-ray analysis of complexes of peptide inhibitors with human recombinant and mouse submandibular renins Journal of Molecular Biology ·M. Badasso, Carlos Frazão, B. L. Sibanda, V. Dhanaraj, Chris Dealwis, J.B. Cooper, S. P. Wood, T.L. Blundell, K Murakami, Hitoshi Miyazaki, Peter Hobart, Kieran F. Geoghegan, Mark Ammirati, Anthony J. Lanzetti, Dennis E. Danley, Serik Kuzembayev, Dennis J. Hoover, Javier Sueiras-Diaz, Dylan M. Jones, Michael Szelke	1992	6
19	Simple Procedure for Recovery of Crystallizable Human Recombinant Renin from Mammalian Cell-Conditioned Medium Advances in experimental medicine and biology ·Kieran F. Geoghegan, Anthony J. Lanzetti, Mark Ammirati, Dennis E. Danley, Diana Barrow, Peter Hobart	1991	1
20	Crystallizable HIV-1 protease derived from expression of the viral pol gene in Escherichia coli Biochemical and Biophysical Research Communications ·Dennis E. Danley, Kieran F. Geoghegan, 程金梅, Joao Cardoso das Neves Neto, James Merson, Steven J. Hawrylik, Cecilia Silva-Díaz, Mark Ammirati, Peter Hobart	1989	18

About Mark Ammirati

Mark Ammirati is a scholar working on Structural Biology, Toxicology, Endocrinology, Diabetes and Metabolism, Oncology and Cellular and Molecular Neuroscience, having authored 20 papers that have together received 1.2k indexed citations. Recurring topics across this work include Peptidase Inhibition and Analysis (6 papers), Diabetes Treatment and Management (4 papers), Neuropeptides and Animal Physiology (4 papers), Glycosylation and Glycoproteins Research (3 papers), Chemical Synthesis and Analysis (3 papers), Glycogen Storage Diseases and Myoclonus (2 papers), Receptor Mechanisms and Signaling (2 papers) and RNA and protein synthesis mechanisms (2 papers). The work is most often cited by research in Molecular Medicine (85 citations), Structural Biology (14 citations), Cancer Research (134 citations), Molecular Biology (598 citations) and Surgery (385 citations). Mark Ammirati has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Dennis E. Danley, Matthew C. Griffor, Xiayang Qiu, Kieran F. Geoghegan, Mahmoud N. Mansour, Andrew P. Seddon, Lise R. Hoth, Virginia L. Rath, Alison H. Varghese and David Cunningham. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Nature Communications, Journal of Medicinal Chemistry, Advances in experimental medicine and biology and Nature Structural & Molecular Biology.

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