David J. Shields

4.5k citations

44 papers · 3.2k indexed · 1 hit paper · h-index 23

Impact in

Hematology top 2%
- Acute Myeloid Leukemia Research
Cancer Research top 5%
- MicroRNA in disease regulation
- Cancer, Hypoxia, and Metabolism
- Cancer-related molecular mechanisms research

Papers in

Immunology and Allergy 4
- Cell Adhesion Molecules Research 4
Genetics 7
- Hemoglobinopathies and Related Disorders 5

Co-authors: David A. Cheresh Nancy A. Dawson William J. Edenfield John C. Byrd Eric A. Murphy Lea Scheppke Lisette M. Acevedo Miller Huang
Journals: Cancer Research (4 papers)Journal of Biological Chemistry (3 papers)PLoS ONE (3 papers)Nature Medicine (2 papers)Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (2 papers)
Partner nations: United States Canada Spain

In The Last Decade

David J. Shields

44 papers receiving 3.1k citations

Hit Papers

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A role for VEGF as a negative regulator of pericyte function and vessel maturation 2008 · 501 citations

Peers

Countries citing papers authored by David J. Shields

Since Specialization

Citations

This map shows the geographic impact of David J. Shields's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David J. Shields with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David J. Shields more than expected).

Fields of papers citing papers by David J. Shields

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David J. Shields. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David J. Shields. The network helps show where David J. Shields may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David J. Shields, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David J. Shields Line = papers co-authored together David J. Shields links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	N6-methyladenosine in DNA promotes genome stability eLife ·Brooke A. Conti, Aна Ашталковска Гајтаноска, Giulia Gallotta, Qing Xiang, Antonella Cravero, Thomas J. McLellan, Chuong Nguyen, 于伯萍, 丑之助二宮, Вікторія Іванівна Чобіток, Parag V. Sahasrabudhe, Jason D. Arroyo, Lei Shang, Benjamin R. Sabari, David J. Shields, Mariano Oppikofer	2024	1
2	Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1 Nucleic Acids Research ·Hallikainen Anja, Min Woo Sung, Shridhar Bhat, Yingrong Xu, Kevin W. Huynh, Seungil Han, Darren C. Johnson, Benedikt Bosbach, David J. Shields, James T. Stivers	2023	2
3	Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics Nucleic Acids Research ·Hallikainen Anja, Kevin W. Huynh, Mark Ammirati, Seungil Han, Ben Bolaños, Richard J. Chavez, Matthew D. Petroski, Benedikt Bosbach, David J. Shields, James T. Stivers	2022	8
4	Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours European Journal of Cancer ·R. H. Atkin, Celine Chen, Ana Isabel Enríquez Rodríguez, Jan Köster, Michele Dowless, Stefan M. Pfister, David J. Shields, Louis F. Stancato, Gilles Vassal, Hubert Caron, Marlinde L. van den Boogaard, Anton G. Henssen, Jan J. Molenaar	2022	9
5	A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas Cancer Research Communications ·Manuel Hidalgo, Rocio García‐Carbonero, Kian‐Huat Lim, Wells A. Messersmith, Ignacio Garrido‐Laguna, Erkut Borazanci, Andrew M. Lowy, L. Jerome Gallagher, Daniel A. Laheru, Vinod H Thourani, Marcos Malumbres, David J. Shields, Joseph E. Grossman, Xin Huang, Vladmyr Miroslav Porto Lobianco, Jean-François Martini, Yanke Yu, Kenneth A. Kern, Teresa Macarulla	2022	5
6	International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer Molecular Cancer Therapeutics ·Gilles Vassal, Peter J. Houghton, Stefan M. Pfister, Malcolm A. Smith, Huib N. Caron, Xiao‐Nan Li, David J. Shields, Olaf Witt, Jan J. Molenaar, Sara Colombetti, Julia Schüler, Wahdian Adjami Adjami	2021	16
7	CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma Cancer Cell ·Vinod H Thourani, Mónica Álvarez‐Fernández, Daniel A. Pauly, Aicha El Bakkali, Camino Menéndez, Pedro P. López‐Casas, Tomás Di Domenico, Tao Xie, Todd VanArsdale, David J. Shields, Manuel Hidalgo, Marcos Malumbres	2020	116
8	Errors with Manual Phenotype Validation: Case Study and Implications. AMIA ·Polina Kukhareva, Catherine J. Staes, Volker Sellin, Phillip B. Warner, David J. Shields, 阿如旱, P. M. ENDRENY, Kensaku Kawamoto	2015	1
9	Mechanism of Action for Combined CDK4/6 and Er Inhibition in ER Positive Breast Cancer Annals of Oncology ·María Koehler, Todd VanArsdale, David J. Shields, Kim Arndt, Jing Yuan, C Sebban, Myles Dworkin, John Chionis, Joan Cao, Cory L. Painter	2014	5
10	The Id3/E47 Axis Mediates Cell-Cycle Control in Human Pancreatic Ducts and Adenocarcinoma Molecular Cancer Research ·Seung Hee Lee, Ergeng Hao, Niloofar Borghei Razavi, James Shapiro, David J. Shields, Andrew M. Lowy, Fred Levine, Pamela Itkin‐Ansari	2011	21
11	IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration Carcinogenesis ·榎吉寿夫, Peter T. Yu, David J. Shields, Randall P. French, K Telezynska, Sherry Niessen, Heather Hoover, David A. Cheresh, Ben Cravatt, Andrew M. Lowy	2011	37
12	MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis Nature Medicine ·Sudarshan Anand, Bharat K. Majeti, Lisette M. Acevedo, Eric A. Murphy, Rajesh Mukthavaram, Lea Scheppke, Miller Huang, David J. Shields, Jeffrey N. Lindquist, Philip E. Lapinski, Philip D. King, Sara M. Weis, David A. Cheresh	2010	418
13	Caspase-8 Association with the Focal Adhesion Complex Promotes Tumor Cell Migration and Metastasis Cancer Research ·Simone Barbero, Ainhoa Mielgo, Vicente A. Torres, Tal Teitz, David J. Shields, David Mikolon, Matthew Bogyo, Daniela Barilá, Jill M. Lahti, David D. Schlaepfer, Dwayne G. Stupack	2009	112
14	RBBP9: A tumor-associated serine hydrolase activity required for pancreatic neoplasia Proceedings of the National Academy of Sciences ·David J. Shields, Sherry Niessen, Eric A. Murphy, Ainhoa Mielgo, Jay S. Desgrosellier, Steven Lau, Leo A. Barnes, Jacqueline Lesperance, Michael Bouvet, David G. Jackson, Benjamin F. Cravatt, David A. Cheresh	2009	52
15	An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression Nature Medicine ·Jay S. Desgrosellier, Leo A. Barnes, David J. Shields, Miller Huang, Steven Lau, Nicolas Prévost, David G. Jackson, Sanford J. Shattil, David A. Cheresh	2009	235
16	The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion Journal of Lipid Research ·Henkjan J. Verkade, Rick Havinga, David J. Shields, Henk Wolters, Vincent W. Bloks, Folkert Kuipers, Dennis E. Vance, Luis B. Agellon	2007	15
17	Membrane Topography of Human Phosphatidylethanolamine N-Methyltransferase Journal of Biological Chemistry ·David J. Shields, Richard Lehner, Luis B. Agellon, Dennis E. Vance	2003	38
18	Structure, expression profile and alternative processing of the human phosphatidylethanolamine N-methyltransferase (PEMT) gene1Sequence data from this article have been deposited with the GenBank Data Library under accession numbers AF294460–AF294468 inclusive.1 Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·David J. Shields, Luis B. Agellon, Dennis E. Vance	2001	30
19	Hematologic Disorders Associated With Deletions of Chromosome 20q:A Clinicopathologic Study of 107 Patients American Journal of Clinical Pathology ·Paul J. Kurtin, Gordon W. Dewald, David J. Shields, Curtis A. Hanson	1996	66
20	Pulmonary hypertension attributable to neoplastic emboli: An autopsy study of 20 cases and a review of literature Cardiovascular Pathology ·David J. Shields, William D. Edwards	1992	38

About David J. Shields

David J. Shields is a scholar working on Immunology and Allergy, Genetics, Oncology, Cell Biology and Hematology, having authored 44 papers that have together received 3.2k indexed citations. Recurring topics across this work include Pancreatic and Hepatic Oncology Research (8 papers), Advanced Breast Cancer Therapies (6 papers), Hemoglobinopathies and Related Disorders (5 papers), Cell Adhesion Molecules Research (4 papers), DNA Repair Mechanisms (3 papers), Cancer-related Molecular Pathways (3 papers), Angiogenesis and VEGF in Cancer (3 papers) and Advanced biosensing and bioanalysis techniques (3 papers). The work is most often cited by research in Hematology (520 citations), Cancer Research (634 citations), Immunology and Allergy (227 citations), Genetics (275 citations) and Molecular Biology (1.7k citations). David J. Shields has collaborated with scholars based in United States, Canada and Spain. Frequent co-authors include David A. Cheresh, Nancy A. Dawson, William J. Edenfield, John C. Byrd, Eric A. Murphy, Lea Scheppke, Lisette M. Acevedo, Miller Huang, Joshua I. Greenberg and Christian Stockmann. Their work appears in journals such as Cancer Research, Journal of Biological Chemistry, PLoS ONE, Nature Medicine and Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.

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