Stephen Orena

1.6k citations

23 papers · 1.2k indexed · 1 hit paper · h-index 14

Impact in

Endocrinology, Diabetes and Metabolism top 10%
- Diabetes Treatment and Management
Molecular Biology top 10%
- PI3K/AKT/mTOR signaling in cancer
- Metabolism, Diabetes, and Cancer

Papers in ⓘ

Molecular Biology 9
- Metabolism, Diabetes, and Cancer 3
Public Health, Environmental and Occupational Health 8
- Malaria Research and Control 8
- Mosquito-borne diseases and control 4
- Research on Leishmaniasis Studies 2

Co-authors: Robert S. Garofalo (4 shared papers)Audrey L. Hildebrandt (2 shared papers)Dominique Brees (2 shared papers)John D. McNeish (2 shared papers)Jeffrey L. Stock (2 shared papers)Kristina Rafidi (2 shared papers)Joan Wicks (2 shared papers)Kevin Coleman (2 shared papers)
Journals: Antimicrobial Agents and Chemotherapy (5 papers)Nature Communications (2 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)Journal of Clinical Investigation (2 papers)Biochemical and Biophysical Research Communications (2 papers)
Partner nations: United States Uganda Switzerland

In The Last Decade

Stephen Orena

21 papers receiving 1.2k citations

Hit Papers

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ 2003 · 594 citations

Peers

Countries citing papers authored by Stephen Orena

Since Specialization

Citations

This map shows the geographic impact of Stephen Orena's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen Orena with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen Orena more than expected).

Fields of papers citing papers by Stephen Orena

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen Orena. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen Orena. The network helps show where Stephen Orena may publish in the future.

Co-authors

The 25 scholars most cited alongside Stephen Orena, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Stephen Orena Line = papers co-authored together Stephen Orena links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ Journal of Clinical Investigation ·Robert S. Garofalo, Stephen Orena, Kristina Rafidi, Anthony J. Torchia, Jeffrey L. Stock, Audrey L. Hildebrandt, Timothy Coskran, Shawn C. Black, Dominique Brees, Joan Wicks, John D. McNeish, Kevin Coleman Hit paper breakdown →	2003	594
2	Inhibition of Glycogen-synthase Kinase 3 Stimulates Glycogen Synthase and Glucose Transport by Distinct Mechanisms in 3T3-L1 Adipocytes Journal of Biological Chemistry ·Stephen Orena, Anthony J. Torchia, Robert S. Garofalo	2000	98
3	Irisin levels correlate with energy expenditure in a subgroup of humans with energy expenditure greater than predicted by fat free mass Metabolism ·Andrew G. Swick, Stephen Orena, Annalouise O’Connor	2013	77
4	Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda Nature Communications ·Patrick K. Tumwebaze, Melissa D. Conrad, Martin Okitwi, Stephen Orena, Oswald Byaruhanga, Thomas Katairo, Jennifer Legac, Shreeya Garg, David Giesbrecht, Sawyer R. Smith, Frida G. Ceja, Samuel L. Nsobya, Jeffrey A. Bailey, Roland A. Cooper, Philip J. Rosenthal	2022	63
5	Binding and uptake of copper from ceruloplasmin Biochemical and Biophysical Research Communications ·Stephen Orena, Christina A. Goode, Maria C. Linder	1986	54
6	Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice Gastroenterology ·Hiroyuki Tsuchiya, Kerry-Ann da Costa, Sangmin Lee, Barbara Renga, Hartmut Jaeschke, Zhihong Yang, Stephen Orena, Michael Goedken, Yuxia Zhang, Bo Kong, Margitta Lebofsky, Swetha Rudraiah, Rana V. Smalling, Grace L. Guo, Stefano Fiorucci, Steven H. Zeisel, Li Wang	2015	48
7	PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathy Frontiers in Pharmacology ·Stephen Orena, Tristan S. Maurer, Li She, Rena J Eudy, Vincent Bernardo, Darla Dash, Paula M. Loria, Mary Ellen Banker, Meera Tugnait, Carlin V. Okerberg, Jessie Qian, Carine M. Boustany‐Kari	2013	44
8	Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study The Lancet Microbe ·Patrick K. Tumwebaze, Thomas Katairo, Martin Okitwi, Oswald Byaruhanga, Stephen Orena, Victor Asua, Marvin Duvalsaint, Jennifer Legac, Sevil Chelebieva, Frida G. Ceja, Stephanie A. Rasmussen, Melissa D. Conrad, Samuel L. Nsobya, Özkan Aydemir, Jeffrey A. Bailey, Brett R. Bayles, Philip J. Rosenthal, Roland A. Cooper	2021	38
9	Amylin and CGRP induce insulin resistance via a receptor distinct from cAMP-coupled CGRP receptor American Journal of Physiology-Endocrinology and Metabolism ·David K. Kreutter, Stephen Orena, Anthony J. Torchia, Leonard G. Contillo, Glenn C. Andrews, Ralph W. Stevenson	1993	37
10	(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: A potent, selective, orally active dipeptidyl peptidase IV inhibitor Bioorganic & Medicinal Chemistry Letters ·Mark Ammirati, Kim Andrews, David Boyer, Anne M. Brodeur, Dennis E. Danley, Shawn D. Doran, Bernard Hulin, Shenping Liu, R. Kirk McPherson, Stephen Orena, Janice C. Parker, Jana Polívková, Xiayang Qiu, Carolyn B. Soglia, Judith L. Treadway, Maria A. VanVolkenburg, Donald C. Wilder, David W. Piotrowski	2009	33
11	TNFα activation of PKCδ, mediated by NFκB and ER stress, cross-talks with the insulin signaling cascade Cellular Signalling ·Michael W. Greene, Mary S. Ruhoff, Christine M. Burrington, Robert S. Garofalo, Stephen Orena	2009	33
12	Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ Journal of Clinical Investigation ·Robert S. Garofalo, Stephen Orena, Kristina Rafidi, Anthony J. Torchia, Jeffrey L. Stock, Audrey L. Hildebrandt, Timothy Coskran, Shawn C. Black, Dominique Brees, Joan Wicks, John D. McNeish, Kevin Coleman	2003	33
13	cis-2,5-Dicyanopyrrolidine Inhibitors of Dipeptidyl Peptidase IV: Synthesis and in Vitro, in Vivo, and X-ray Crystallographic Characterization Journal of Medicinal Chemistry ·Stephen W. Wright, Mark Ammirati, Kim Andrews, Anne M. Brodeur, Dennis E. Danley, Shawn D. Doran, Jay S. Lillquist, Lester D. McClure, R. Kirk McPherson, Stephen Orena, Janice C. Parker, Jana Polívková, Xiayang Qiu, Walter C. Soeller, Carolyn B. Soglia, Judith L. Treadway, Maria A. VanVolkenburg, Hong Wang, Donald C. Wilder, Thanh V. Olson	2006	28
14	Suppression of insulin-Stimulated glucose transport in L6 myocytes by calcitonin gene-related peptide Biochemical and Biophysical Research Communications ·David K. Kreutter, Stephen Orena, Kim Andrews	1989	19
15	(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: Synthesis, in vitro, in vivo, and X-ray crystallographic characterization Bioorganic & Medicinal Chemistry Letters ·Stephen W. Wright, Mark Ammirati, Kim Andrews, Anne M. Brodeur, Dennis E. Danley, Shawn D. Doran, Jay S. Lillquist, Shenping Liu, Lester D. McClure, R. Kirk McPherson, Thanh V. Olson, Stephen Orena, Janice C. Parker, Benjamin N. Rocke, Walter C. Soeller, Carolyn B. Soglia, Judith L. Treadway, Maria A. VanVolkenburg, Zhengrong Zhao, Eric Cox	2007	13
16	Extracts of Fruits and Vegetables Activate the Antioxidant Response Element in IMR-32 Cells Journal of Nutrition ·Stephen Orena, Jennifer Owen, Fuxia Jin, Morgan Fabian, Nicholas D. Gillitt, Steven H. Zeisel	2015	10
17	Decreased Susceptibility to Dihydrofolate Reductase Inhibitors Associated With Genetic Polymorphisms in Ugandan Plasmodium falciparum Isolates The Journal of Infectious Diseases ·Oriana Kreutzfeld, Patrick K. Tumwebaze, Oswald Byaruhanga, Thomas Katairo, Martin Okitwi, Stephen Orena, Stephanie A. Rasmussen, Jennifer Legac, Melissa D. Conrad, Samuel L. Nsobya, Özkan Aydemir, Jeffrey A. Bailey, Maëlle Duffey, Roland A. Cooper, Philip J. Rosenthal	2021	4
18	Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors Antimicrobial Agents and Chemotherapy ·Shreeya Garg, Oriana Kreutzfeld, Sevil Chelebieva, Patrick K. Tumwebaze, Oswald Byaruhanga, Martin Okitwi, Stephen Orena, Thomas Katairo, Samuel L. Nsobya, Melissa D. Conrad, Özkan Aydemir, Jennifer Legac, Alexandra E. Gould, Brett R. Bayles, Jeffrey A. Bailey, Maëlle Duffey, Gang Lin, Laura A. Kirkman, Roland A. Cooper, Philip J. Rosenthal	2022	2
19	The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates Antimicrobial Agents and Chemotherapy ·Martin Okitwi, Douglas A. Shoue, Lisa A. Checkley, Stephen Orena, Frida G. Ceja, Yoweri Taremwa, Patrick K. Tumwebaze, Thomas Katairo, Oswald Byaruhanga, Mackenzie A. C. Sievert, Shreeya Garg, Oriana Kreutzfeld, Jennifer Legac, Jeffrey A. Bailey, Samuel L. Nsobya, Melissa D. Conrad, Philip J. Rosenthal, Michael T. Ferdig, Roland A. Cooper	2024	1
20	Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum Isolates Antimicrobial Agents and Chemotherapy ·Oriana Kreutzfeld, Stephanie A. Rasmussen, Aarti Ramanathan, Patrick K. Tumwebaze, Oswald Byaruhanga, Thomas Katairo, Victor Asua, Martin Okitwi, Stephen Orena, Jennifer Legac, Melissa D. Conrad, Samuel L. Nsobya, Özkan Aydemir, Jeffrey A. Bailey, Maëlle Duffey, Brett R. Bayles, Akhil B. Vaidya, Roland A. Cooper, Philip J. Rosenthal	2021	1

About Stephen Orena

Stephen Orena is a scholar working on Molecular Biology, Public Health, Environmental and Occupational Health, Endocrinology, Diabetes and Metabolism, Cellular and Molecular Neuroscience and Computational Theory and Mathematics, having authored 23 papers that have together received 1.2k indexed citations. Recurring topics across this work include Malaria Research and Control (8 papers), Computational Drug Discovery Methods (5 papers), Neuropeptides and Animal Physiology (5 papers), Diabetes Treatment and Management (5 papers), Mosquito-borne diseases and control (4 papers), Metabolism, Diabetes, and Cancer (3 papers), Peptidase Inhibition and Analysis (3 papers) and Research on Leishmaniasis Studies (2 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (178 citations), Molecular Biology (707 citations), Physiology (229 citations), Cell Biology (95 citations) and Endocrine and Autonomic Systems (36 citations). Stephen Orena has collaborated with scholars based in United States, Uganda and Switzerland. Frequent co-authors include Robert S. Garofalo, Audrey L. Hildebrandt, Dominique Brees, John D. McNeish, Jeffrey L. Stock, Kristina Rafidi, Joan Wicks, Kevin Coleman, Shawn C. Black and Timothy Coskran. Their work appears in journals such as Antimicrobial Agents and Chemotherapy, Nature Communications, Bioorganic & Medicinal Chemistry Letters, Journal of Clinical Investigation and Biochemical and Biophysical Research Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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