Ye Che

3.2k citations

43 papers · 2.4k · 1 hit paper · h-index 24

Impact in

Infectious Diseases top 5%
- SARS-CoV-2 and COVID-19 Research
Molecular Medicine top 5%

Papers in

Molecular Biology 29
- Chemical Synthesis and Analysis 13
- Protein Kinase Regulation and GTPase Signaling 3
Molecular Medicine 5
- Antibiotic Resistance in Bacteria 5

Co-authors: Garland R. Marshall (9 shared papers)Veerabahu Shanmugasundaram (6 shared papers)Bernard R. Brooks (3 shared papers)Seungil Han (4 shared papers)Mark C. Noe (2 shared papers)Robert Abel (1 shared paper)Woody Sherman (1 shared paper)Byungchan Kim (1 shared paper)
Journals: Journal of Medicinal Chemistry (7 papers)Genes (2 papers)The Journal of Organic Chemistry (2 papers)Biopolymers (2 papers)The AAPS Journal (2 papers)
Partner nations: United States China United Kingdom

In The Last Decade

Ye Che

43 papers receiving 2.3k citations

Ye Che's Hit Papers

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BNT162b vaccines protect rhesus macaques from SARS-CoV-2 2021 · 543 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2021 Nature

Peers

Countries citing papers authored by Ye Che

Since Specialization

Citations

This map shows the geographic impact of Ye Che's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ye Che with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ye Che more than expected).

Fields of papers citing papers by Ye Che

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ye Che. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ye Che. The network helps show where Ye Che may publish in the future.

Co-authors

The 25 scholars most cited alongside Ye Che, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ye Che Line = papers co-authored together Ye Che links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 43 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	BNT162b vaccines protect rhesus macaques from SARS-CoV-2 Nature ·Annette B. Vogel, Isis Kanevsky, Ye Che, Kena A. Swanson, Alexander Muik, Mathias Vormehr, Lena M. Kranz, Kerstin C. Walzer Hit paper breakdown →	2021	543
2	Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors Journal of Medicinal Chemistry ·Mark E. Flanagan, Joseph A. Abramite, Dennis P. Anderson, ANN E. AULABAUGH, Upendra P. Dahal, Adam M. Gilbert, Chao Li, Justin I. Montgomery	2014	283
3	Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans Journal of Medicinal Chemistry ·Atli Thorarensen, Martin E. Dowty, Mary Ellen Banker, Brian M. Juba, Jason M. Jussif, Tsung H. Lin, Fabien Vincent, Robert Czerwiński	2017	142
4	Thermodynamic analysis of water molecules at the surface of proteins and applications to binding site prediction and characterization Proteins Structure Function and Bioinformatics ·Thijs Beuming, Ye Che, Robert Abel, Byungchan Kim, Veerabahu Shanmugasundaram, Woody Sherman	2011	117
5	Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes Nature Chemical Biology ·James Schiemer, Reto Horst, Yilin Meng, Justin I. Montgomery, Yingrong Xu, Xidong Feng, Kris A. Borzilleri, Daniel P. Uccello	2020	92
6	Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections Journal of Medicinal Chemistry ·Justin I. Montgomery, Matthew F. Brown, Usa Datta Reilly, Loren M. Price, Joseph A. Abramite, Joel T. Arcari, Rose A. Barham, Ye Che	2012	88
7	Discovery of a Highly Selective Glycogen Synthase Kinase‐3 Inhibitor (PF‐04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging Angewandte Chemie International Edition ·Steven H. Liang, Jinshan Michael Chen, Marc D. Normandin, Jeanne S. Chang, George Chang, Christine K. Taylor, Patrick E. Trapa, Mark S. Plummer	2016	87
8	Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections Journal of Medicinal Chemistry ·Matthew F. Brown, Usa Datta Reilly, Joseph A. Abramite, Joel T. Arcari, Robert M. Oliver, Rose A. Barham, Ye Che, Jinshan Michael Chen	2011	83
9	Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20 Nature Communications ·David Jonathan Wasilko, Zachary Lee Johnson, Mark J. Ammirati, Ye Che, Matthew C. Griffor, Seungil Han, Huixian Wu	2020	82
10	Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion Science Advances ·Yuhang Liu, Kyle P. Heim, Ye Che, Xiaoyuan Chi, Xiayang Qiu, Seungil Han, Philip R. Dormitzer, Xinzhen Yang	2021	75
11	Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine Science Translational Medicine ·Ye Che, Alexey V. Gribenko, Xi Song, Luke D. Handke, Kari Sweeney Efferen, Kristin R. Tompkins, Srinivas Kodali, Lorna Nuñez	2023	71
12	Development of small molecules designed to modulate protein–protein interactions Journal of Computer-Aided Molecular Design ·Ye Che, Bernard R. Brooks, Garland R. Marshall	2006	61
13	Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation eLife ·Xiaodi Yu, Olga V. Plotnikova, Paul D. Bonin, Timothy A. Subashi, Thomas J. McLellan, Darren S. Dumlao, Ye Che, Yin Yao Dong	2019	61
14	Impact of Cis‐proline analogs on peptide conformation Biopolymers ·Ye Che, Garland R. Marshall	2005	57
15	Inducing protein-protein interactions with molecular glues Bioorganic & Medicinal Chemistry Letters ·Ye Che, Adam M. Gilbert, Veerabahu Shanmugasundaram, Mark C. Noe	2018	57
16	Engineering Cyclic Tetrapeptides Containing Chimeric Amino Acids as Preferred Reverse-Turn Scaffolds Journal of Medicinal Chemistry ·Ye Che, Garland R. Marshall	2005	53
17	Siderophore Receptor-Mediated Uptake of Lactivicin Analogues in Gram-Negative Bacteria Journal of Medicinal Chemistry ·Jeremy T. Starr, Matthew F. Brown, Lisa M. Aschenbrenner, Nicole L. Caspers, Ye Che, Brian S. Gerstenberger, Michael D. Huband, John D. Knafels	2014	52
18	Non-Traditional Antibacterial Screening Approaches for the Identification of Novel Inhibitors of the Glyoxylate Shunt in Gram-Negative Pathogens PLoS ONE ·Kelly C. Fahnoe, Mark E. Flanagan, Glenn Gibson, Veerabahu Shanmugasundaram, Ye Che, Andrew P. Tomaras	2012	48
19	Impact of Azaproline on Peptide Conformation The Journal of Organic Chemistry ·Ye Che, Garland R. Marshall	2004	44
20	Privileged scaffolds targeting reverse-turn and helix recognition Expert Opinion on Therapeutic Targets ·Ye Che, Garland R. Marshall	2007	32

About Ye Che

Ye Che is a scholar working on Molecular Biology, Molecular Medicine, Organic Chemistry, Infectious Diseases and Spectroscopy, having authored 43 papers that have together received 2.4k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (13 papers), Click Chemistry and Applications (5 papers), Monoclonal and Polyclonal Antibodies Research (5 papers), Antibiotic Resistance in Bacteria (5 papers), Analytical Chemistry and Chromatography (4 papers), Plant Molecular Biology Research (3 papers), Protein Kinase Regulation and GTPase Signaling (3 papers) and Plant Stress Responses and Tolerance (3 papers). The work is most often cited by research in Infectious Diseases (485 citations), Molecular Medicine (129 citations), Molecular Biology (1.3k citations), Organic Chemistry (508 citations) and Oncology (364 citations). Ye Che has collaborated with scholars based in United States, China and United Kingdom. Frequent co-authors include Garland R. Marshall, Veerabahu Shanmugasundaram, Bernard R. Brooks, Seungil Han, Mark C. Noe, Robert Abel, Woody Sherman, Byungchan Kim, Adam M. Gilbert and Thijs Beuming. Their work appears in journals such as Journal of Medicinal Chemistry, Genes, The Journal of Organic Chemistry, Biopolymers and The AAPS Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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