Bruce A. Lefker

2.6k total citations
40 papers, 1.3k citations indexed

About

Bruce A. Lefker is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Bruce A. Lefker has authored 40 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 14 papers in Organic Chemistry and 9 papers in Oncology. Recurrent topics in Bruce A. Lefker's work include Asymmetric Synthesis and Catalysis (9 papers), Bone health and treatments (6 papers) and Estrogen and related hormone effects (6 papers). Bruce A. Lefker is often cited by papers focused on Asymmetric Synthesis and Catalysis (9 papers), Bone health and treatments (6 papers) and Estrogen and related hormone effects (6 papers). Bruce A. Lefker collaborates with scholars based in United States, Russia and Bulgaria. Bruce A. Lefker's co-authors include A. I. MEYERS, T G Gabig, Mark A. Seefeld, Theodore G. Gabig, David D. Thompson, James F. Blake, Kimberly O. Cameron, Thomas A. Owen, Vishwas Paralkar and Thomas A. Brown and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Bruce A. Lefker

40 papers receiving 1.2k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Bruce A. Lefker United States 22 539 452 195 193 151 40 1.3k
Sonia Lamontagne Canada 19 525 1.0× 314 0.7× 87 0.4× 463 2.4× 191 1.3× 22 1.3k
Karl F. Erhard United States 22 772 1.4× 262 0.6× 136 0.7× 62 0.3× 205 1.4× 43 1.4k
Jean‐Michel Rondeau Switzerland 23 843 1.6× 300 0.7× 182 0.9× 245 1.3× 259 1.7× 43 1.6k
Peppi Prasit United States 21 592 1.1× 242 0.5× 120 0.6× 189 1.0× 126 0.8× 44 1.2k
Thomas Buhl Switzerland 18 314 0.6× 294 0.7× 83 0.4× 60 0.3× 179 1.2× 25 879
David Thomson United States 20 361 0.7× 265 0.6× 198 1.0× 233 1.2× 80 0.5× 59 1.1k
Dilip Amin United States 14 529 1.0× 212 0.5× 67 0.3× 102 0.5× 280 1.9× 26 1.6k
Ruth A. Henderson United States 12 329 0.6× 213 0.5× 262 1.3× 90 0.5× 242 1.6× 15 1.4k
John H. Hutchinson United States 26 882 1.6× 654 1.4× 146 0.7× 279 1.4× 147 1.0× 90 1.9k
Dennis S. Yamashita United States 22 1.6k 2.9× 466 1.0× 59 0.3× 125 0.6× 326 2.2× 38 2.2k

Countries citing papers authored by Bruce A. Lefker

Since Specialization
Citations

This map shows the geographic impact of Bruce A. Lefker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce A. Lefker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce A. Lefker more than expected).

Fields of papers citing papers by Bruce A. Lefker

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce A. Lefker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce A. Lefker. The network helps show where Bruce A. Lefker may publish in the future.

Co-authorship network of co-authors of Bruce A. Lefker

This figure shows the co-authorship network connecting the top 25 collaborators of Bruce A. Lefker. A scholar is included among the top collaborators of Bruce A. Lefker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bruce A. Lefker. Bruce A. Lefker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Ratnayake, Anokha S., Mark E. Flanagan, Timothy L. Foley, et al.. (2021). Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS). Bioorganic & Medicinal Chemistry. 41. 116205–116205. 11 indexed citations
2.
Shraga, Amit, Payam Khoshkenar, Nicolas Germain, et al.. (2018). Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor. Cell chemical biology. 26(1). 98–108.e5. 47 indexed citations
3.
Rose, Colin R., et al.. (2016). Practical synthesis of capromorelin, a growth hormone secretagogue, via a crystallization-induced dynamic resolution. Bioorganic & Medicinal Chemistry. 25(3). 1000–1003. 4 indexed citations
4.
Kalgutkar, Amit S., Kosea S. Frederick, Heather L. Hatch, et al.. (2013). Identification of a novel, non-tetrahydroquinoline variant of the cholesteryl ester transfer protein (CETP) inhibitor torcetrapib, with improved aqueous solubility. Xenobiotica. 44(7). 591–605. 2 indexed citations
5.
Mascitti, Vincent, Benjamin D. Stevens, Chulho Choi, et al.. (2011). Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor. Bioorganic & Medicinal Chemistry Letters. 21(5). 1306–1309. 21 indexed citations
6.
Liu, Kevin K.‐C., Bruce A. Lefker, Mark A. Dombroski, et al.. (2010). Orally active and brain permeable proline amides as highly selective 5HT2c agonists for the treatment of obesity. Bioorganic & Medicinal Chemistry Letters. 20(7). 2365–2369. 7 indexed citations
7.
Cameron, Kimberly O., Bruce A. Lefker, Hua Zhu Ke, et al.. (2009). Discovery of CP-533536: An EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. Bioorganic & Medicinal Chemistry Letters. 19(7). 2075–2078. 24 indexed citations
8.
Mitchell, Lorna H., Lain‐Yen Hu, Maria Nguyen, et al.. (2009). Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production. Bioorganic & Medicinal Chemistry Letters. 19(8). 2176–2178. 7 indexed citations
9.
Hu, Lain‐Yen, Catherine R. Kostlan, Bruce A. Lefker, et al.. (2007). Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production. Bioorganic & Medicinal Chemistry Letters. 17(20). 5529–5532. 9 indexed citations
10.
Cameron, Kimberly O., Bruce A. Lefker, Margaret Y. Chu‐Moyer, et al.. (2006). Discovery of highly selective EP4 receptor agonists that stimulate new bone formation and restore bone mass in ovariectomized rats. Bioorganic & Medicinal Chemistry Letters. 16(7). 1799–1802. 19 indexed citations
11.
Ke, Hua Zhu, David T. Crawford, Hong Qi, et al.. (2006). A Nonprostanoid EP4 Receptor Selective Prostaglandin E2 Agonist Restores Bone Mass and Strength in Aged, Ovariectomized Rats. Journal of Bone and Mineral Research. 21(4). 565–575. 51 indexed citations
12.
Chesworth, Richard, Michael P. Zawistoski, Bruce A. Lefker, et al.. (2004). Tetrahydroisoquinolines as subtype selective estrogen agonists/antagonists. Bioorganic & Medicinal Chemistry Letters. 14(11). 2729–2733. 32 indexed citations
13.
Pan, Lydia C., Philip A. Carpino, Bruce A. Lefker, et al.. (2001). Preclinical Pharmacology of CP-424,391, an Orally Active Pyrazolidinone-Piperidine Growth Hormone Secretagogue. Endocrine. 14(1). 121–132. 33 indexed citations
14.
MEYERS, A. I., Mark A. Seefeld, Bruce A. Lefker, James F. Blake, & Paul G. Williard. (1998). ChemInform Abstract: Stereoselective Alkylations in Rigid Systems. Effect of Remote Substituents on π‐Facial Additions to Lactam Enolates. Stereoselectronic and Steric Effects.. ChemInform. 29(49). 4 indexed citations
15.
Hoover, Dennis J., Bruce A. Lefker, Robert L. Rosati, et al.. (1995). Discovery of Inhibitors of Human Renin with High Oral Bioavailability. Advances in experimental medicine and biology. 362. 167–180. 11 indexed citations
16.
Lefker, Bruce A., William H. Martin, Ingrid A. Stock, et al.. (1995). Rational design, synthesis, and X-ray structure of renin inhibitors with extended P1 sidechains. Bioorganic & Medicinal Chemistry Letters. 5(22). 2623–2626. 7 indexed citations
17.
18.
MEYERS, A. I. & Bruce A. Lefker. (1986). Chiral bicyclic lactams for asymmetric synthesis of quaternary carbons. The total synthesis of (-)-.alpha.-cuparenone. The Journal of Organic Chemistry. 51(9). 1541–1544. 41 indexed citations
19.
Gabig, Theodore G. & Bruce A. Lefker. (1986). [18] NADPH oxidase from polymorphonuclear cells. Methods in enzymology on CD-ROM/Methods in enzymology. 132. 355–364. 5 indexed citations
20.
Gabig, Theodore G. & Bruce A. Lefker. (1984). Catalytic properties of the resolved flavoprotein and cytochrome B components of the NADPH dependent O2−• generating oxidase from human neutrophils. Biochemical and Biophysical Research Communications. 118(2). 430–436. 50 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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