Tom L. Blundell

61.6k total citations · 11 hit papers
505 papers, 45.7k citations indexed

About

Tom L. Blundell is a scholar working on Molecular Biology, Materials Chemistry and Infectious Diseases. According to data from OpenAlex, Tom L. Blundell has authored 505 papers receiving a total of 45.7k indexed citations (citations by other indexed papers that have themselves been cited), including 422 papers in Molecular Biology, 171 papers in Materials Chemistry and 59 papers in Infectious Diseases. Recurrent topics in Tom L. Blundell's work include Enzyme Structure and Function (167 papers), Protein Structure and Dynamics (150 papers) and RNA and protein synthesis mechanisms (69 papers). Tom L. Blundell is often cited by papers focused on Enzyme Structure and Function (167 papers), Protein Structure and Dynamics (150 papers) and RNA and protein synthesis mechanisms (69 papers). Tom L. Blundell collaborates with scholars based in United Kingdom, United States and South Sudan. Tom L. Blundell's co-authors include Andrej Săli, David B. Ascher, Douglas E. V. Pires, Kenji Mizuguchi, B. L. Sibanda, Jiye Shi, Chris Abell, Janet M. Thornton, Dimitri Y. Chirgadze and John P. Overington and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Tom L. Blundell

497 papers receiving 44.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Comparative Protein Modelling by Satisfaction of Spatial Restraints

1993 10.9k citations Tom L. Blundell et al. profile →
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

2015 3.6k citations Tom L. Blundell, David B. Ascher et al. Journal of Medicinal Chemistry profile →
FUGUE: sequence-structure homology recognition using environment-specific substitution tables and structure-dependent gap penalties11Edited by B. Honig

2001 1.0k citations Tom L. Blundell et al. profile →
The TRANSPARENT TESTA GLABRA1 Locus, Which Regulates Trichome Differentiation and Anthocyanin Biosynthesis in Arabidopsis, Encodes a WD40 Repeat Protein

1999 781 citations Tom L. Blundell et al. profile →
mCSM: predicting the effects of mutations in proteins using graph-based signatures

2013 738 citations David B. Ascher, Tom L. Blundell et al. profile →
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

2000 567 citations Tom L. Blundell et al. profile →
Insights into DNA recombination from the structure of a RAD51–BRCA2 complex

2002 540 citations Tom L. Blundell et al. profile →
Knowledge-based prediction of protein structures and the design of novel molecules

1987 505 citations Tom L. Blundell, B. L. Sibanda et al. profile →
Structure of Rhombohedral 2 Zinc Insulin Crystals

1969 372 citations Tom L. Blundell et al. profile →
Machine learning-aided generative molecular design

2024 68 citations Tom L. Blundell et al. profile →
Structure-based drug design with equivariant diffusion models

2024 52 citations Tom L. Blundell et al. profile →

Peers

Countries citing papers authored by Tom L. Blundell

Since Specialization

Citations

This map shows the geographic impact of Tom L. Blundell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tom L. Blundell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tom L. Blundell more than expected).

Fields of papers citing papers by Tom L. Blundell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tom L. Blundell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tom L. Blundell. The network helps show where Tom L. Blundell may publish in the future.

Co-authorship network of co-authors of Tom L. Blundell

This figure shows the co-authorship network connecting the top 25 collaborators of Tom L. Blundell. A scholar is included among the top collaborators of Tom L. Blundell based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tom L. Blundell. Tom L. Blundell is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	A Fragment‐Based Competitive ¹⁹F LB‐NMR Platform For Hotspot‐Directed Ligand Profiling 2024 ·Angewandte Chemie International Edition ·William J. McCarthy, S.E. Thomas, (unknown), (unknown), R. Andres Floto, Glyn Williams, Tom L. Blundell, Anthony G. Coyne, Chris Abell	0
2	A Fragment‐Based Competitive ¹⁹F LB‐NMR Platform For Hotspot‐Directed Ligand Profiling 2024 ·Angewandte Chemie ·William J. McCarthy, S.E. Thomas, (unknown), (unknown), R. Andres Floto, Glyn Williams, Tom L. Blundell, Anthony G. Coyne, Chris Abell	1
3	Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference** 2023 ·Angewandte Chemie International Edition ·Jamal El Bakali, M. Błaszczyk, Joanna C. Evans, (unknown), William J. McCarthy, (unknown), M.V.B. Dias, Eachan O. Johnson, Anthony G. Coyne, Valerie Mizrahi, Tom L. Blundell, Chris Abell, Christina Spry	8
4	Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference** 2023 ·Angewandte Chemie ·Jamal El Bakali, M. Błaszczyk, Joanna C. Evans, (unknown), William J. McCarthy, (unknown), M.V.B. Dias, Eachan O. Johnson, Anthony G. Coyne, Valerie Mizrahi, Tom L. Blundell, Chris Abell, Christina Spry	1
5	Unheeded SARS-CoV-2 proteins? A deep look into negative-sense RNA 2022 ·Briefings in Bioinformatics ·Martin Bartas, (unknown), Christopher A. Beaudoin, Ebbe Toftgaard Poulsen, Jiří Červeň, Václav Brázda, Vladimı́r Špunda, Tom L. Blundell, Petr Pečínka	17
6	Mycobacterium abscessus pathogenesis identified by phenogenomic analyses 2022 ·Nature Microbiology ·Lucas Boeck, Sophie Burbaud, Marcin J. Skwark, William H. Pearson, (unknown), (unknown), (unknown), Aaron Weimann, Isobel Everall, Josephine M. Bryant, Sony Malhotra, Bridget P. Bannerman, Katrin Kierdorf, Tom L. Blundell, Marc Dionne, Julian Parkhill, R. Andrés Floto	24
7	SAP domain forms a flexible part of DNA aperture in Ku70/80 2021 ·FEBS Journal ·Aleš Hnı́zda, Petr Těšina, Thanh Nguyen, Zdeněk Kukačka, Lukas Kater, Amanda K. Chaplin, Roland Beckmann, David B. Ascher, Petr Novák, Tom L. Blundell	11
8	Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4′-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity 2021 ·ACS Infectious Diseases ·Joanna C. Evans, (unknown), John Post, V. Mendes, Zhe Wang, Navid Nahiyaan, (unknown), Stephen Thompson, Simon R. Green, Peter C. Ray, Jeannine Hess, Christina Spry, Anthony G. Coyne, Chris Abell, Helena I. Boshoff, Paul G. Wyatt, Kyu Y. Rhee, Tom L. Blundell, Clifton E. Barry, Valerie Mizrahi	6
9	Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification 2020 ·Nucleic Acids Research ·S.E. Thomas, Andrew Whitehouse, Karen Brown, Sophie Burbaud, Juan M. Belardinelli, (unknown), Ramanuj Lahiri, M. Daben J. Libardo, Pooja Gupta, Sony Malhotra, Helena I. Boshoff, Mary Jackson, Chris Abell, Anthony G. Coyne, Tom L. Blundell, R. Andres Floto, V. Mendes	18
10	ProCarbDB: a database of carbohydrate-binding proteins 2019 ·Nucleic Acids Research ·(unknown), Pedro Henrique Monteiro Torres, David B. Ascher, Tom L. Blundell, Sony Malhotra	24
11	Mabellini: a genome-wide database for understanding the structural proteome and evaluating prospective antimicrobial targets of the emerging pathogen Mycobacterium abscessus 2019 ·Database ·Marcin J. Skwark, Pedro Henrique Monteiro Torres, (unknown), Bridget P. Bannerman, R. Andres Floto, Tom L. Blundell	14
12	Development of Inhibitors against Mycobacterium abscessus tRNA (m ¹ G37) Methyltransferase (TrmD) Using Fragment-Based Approaches 2019 ·Journal of Medicinal Chemistry ·Andrew Whitehouse, S.E. Thomas, Karen Brown, Alexander Fanourakis, Daniel Shiu‐Hin Chan, M. Daben J. Libardo, V. Mendes, Helena I. Boshoff, R. Andres Floto, Chris Abell, Tom L. Blundell, Anthony G. Coyne	33
13	Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae 2018 ·Scientific Reports ·Sundeep Chaitanya Vedithi, Sony Malhotra, (unknown), (unknown), Nanda Kishore, (unknown), (unknown), Lakshmi Rajan, (unknown), David B. Ascher, Eddy Arnold, Tom L. Blundell	38
14	DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair 2017 ·Science ·B. L. Sibanda, Dimitri Y. Chirgadze, David B. Ascher, Tom L. Blundell	140
15	PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair 2015 ·Science ·Takashi Ochi, Andrew N. Blackford, Julia Coates, Satpal S. Jhujh, Shahid Mehmood, Naoka Tamura, Jon Travers, Qian Wu, Viji M. Draviam, Carol V. Robinson, Tom L. Blundell, Stephen P. Jackson	237
16	Developing Antagonists for the Met-HGF/SF Protein–Protein Interaction Using a Fragment-Based Approach 2015 ·Molecular Cancer Therapeutics ·Anja Winter, Anna Sigurdardottir, Danielle DiCara, Giovanni Valenti, Tom L. Blundell, Ermanno Gherardi	7
17	Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding 2015 ·Chemical Science ·Anna Sigurdardottir, Anja Winter, (unknown), Marco Fragai, Dimitri Y. Chirgadze, David B. Ascher, Tom L. Blundell, Ermanno Gherardi	18
18	Targeting LMO2 with a Peptide Aptamer Establishes a Necessary Function in Overt T-Cell Neoplasia 2009 ·Cancer Research ·Alex Appert, Chang‐Hoon Nam, (unknown), Eva‐María Priego, Ricardo Núñez Miguel, Tom L. Blundell, Lesley Drynan, (unknown), Tomoyuki Tanaka, Terence H. Rabbitts	36
19	Atomic Interactions and Profile of Small Molecules Disrupting Protein–Protein Interfaces: the TIMBAL Database 2009 ·Chemical Biology & Drug Design ·Alícia P. Higueruelo, Adrian Schreyer, G. Richard Bickerton, William R. Pitt, Colin R. Groom, Tom L. Blundell	129
20	Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics 2009 ·Molecular BioSystems ·Semin Lee, Alan Brown, William R. Pitt, Alícia P. Higueruelo, Sungsam Gong, G. Richard Bickerton, Adrian Schreyer, (unknown), Alison J. Baylay, Tom L. Blundell	8

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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