Frank McCormick

80.5k citations

381 papers · 57.5k indexed · 28 hit papers · h-index 118

Impact in

Molecular Biology top 0.01%
- Protein Kinase Regulation and GTPase Signaling
- PI3K/AKT/mTOR signaling in cancer
- Wnt/β-catenin signaling in development and cancer
- Melanoma and MAPK Pathways
- Cancer-related gene regulation
Cell Biology top 0.02%
- Cellular transport and secretion

Papers in

Oncology 125
- Cancer-related Molecular Pathways 70
Molecular Biology 291
- Protein Kinase Regulation and GTPase Signaling 125
- Melanoma and MAPK Pathways 50
- PI3K/AKT/mTOR signaling in cancer 48
- Cell death mechanisms and regulation 32
- Wnt/β-catenin signaling in development and cancer 25

Co-authors: Osamu Tetsu Henry R. Bourne D.A.R. Sanders Mark S. Boguski Charles J. Sherr Meg Trahey Simon J. Cook Gideon Bollag
Journals: Molecular and Cellular Biology (27 papers)Proceedings of the National Academy of Sciences (27 papers)Journal of Biological Chemistry (25 papers)Science (18 papers)Oncogene (15 papers)
Partner nations: United States United Kingdom Japan

In The Last Decade

Frank McCormick

374 papers receiving 56.0k citations

Hit Papers

15 papers align trajectories log scale

The metabolic landscape of RAS-driven cancers from biology to therapy 2021 · 190 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Nature Cancer
2020 Nature Reviews Drug Discovery
2017 Cell
2017 Nature
2014 Nature reviews. Cancer
2014 Cancer Cell
2013 Cancer Cell
2003 Nature Genetics
2002 Cancer Cell
1999 Nature
1998 Science
1997 Nature Medicine
1997 Science
1996 Science
1996 Cell
1995 Nature
1995 Nature
1993 Nature
1993 Science
1992 Cell
1991 Nature
1990 Science
1990 Nature
1990 Cell
1990 Cell
1990 Nature
1988 Proceedings of the National Academy of Sciences
1987 Science

Peers

Countries citing papers authored by Frank McCormick

Since Specialization

Citations

This map shows the geographic impact of Frank McCormick's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank McCormick with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank McCormick more than expected).

Fields of papers citing papers by Frank McCormick

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank McCormick. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank McCormick. The network helps show where Frank McCormick may publish in the future.

Co-authors

The 25 scholars most cited alongside Frank McCormick, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frank McCormick Line = papers co-authored together Frank McCormick links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome–associated cardiac hypertrophy Science Advances ·Antonio Cuevas-Navarro, Juan Pablo Afanador, Kendry Socovoski, Monalisa Swain, Gülzade Uysal, John Columbus, 徐绍史, Alice Cheng, Simon Messing, Thomas J. Turbyville, Dhirendra K. Simanshu, Matthew J. Sale, Frank McCormick, Andrew G. Stephen, Pau Castel	2023	12
2	Structure of the SHOC2–MRAS–PP1C complex provides insights into RAF activation and Noonan syndrome Nature Structural & Molecular Biology ·Daniel A. Bonsor, Patrick Alexander, Kelly Snead, Nicole Hartig, Matthew Drew, Simon Messing, Lorenzo I. Finci, Dwight V. Nissley, Frank McCormick, Dominic Esposito, Pablo Rodriguez‐Viciana, Andrew G. Stephen, Dhirendra K. Simanshu	2022	27
3	KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation Nature Communications ·Timothy H. Tran, Albert H. Chan, Lucy C. Young, Lakshman Bindu, Chris Neale, Simon Messing, Srisathiyanarayanan Dharmaiah, Troy Taylor, John-Paul Denson, Dominic Esposito, Dwight V. Nissley, Andrew G. Stephen, Frank McCormick, Dhirendra K. Simanshu	2021	139
4	UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth Proceedings of the National Academy of Sciences ·Andrew L. Wolfe, Qingwen Zhou, Eneda Toska, Jacqueline Galeas, Angel A. Ku, Richard P. Koche, Sourav Bandyopadhyay, Maurizio Scaltriti, Carlito B. Lebrilla, Frank McCormick, Sung Eun Kim	2021	35
5	Undermining Glutaminolysis Bolsters Chemotherapy While NRF2 Promotes Chemoresistance in KRAS-Driven Pancreatic Cancers Cancer Research ·Suman Mukhopadhyay, Debanjan Goswami, Pavan P. Adiseshaiah, William Burgan, Ming Yi, Theresa M. Guerin, С. В. Козлов, Dwight V. Nissley, Frank McCormick	2020	193
6	Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders Proceedings of the National Academy of Sciences ·CATHERINE MORGAN, Nikki K. Lytle, Seth T. Gammon, Amanda de Farias Santos, Tikvah K. Hayes, Margie N. Sutton, Robert C. Bast, Channing J. Der, David Piwnica‐Worms, Frank McCormick, Geoffrey M. Wahl	2020	12
7	Integration of multiple biological contexts reveals principles of synthetic lethality that affect reproducibility Nature Communications ·Angel A. Ku, محمود اردهامی, Xin Zhao, Khyati N. Shah, Sameera Kongara, Di Wu, Frank McCormick, Allan Balmain, Sourav Bandyopadhyay	2020	27
8	Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF-Driven Tumors through Autocrine FGFR Pathway Activation Clinical Cancer Research ·Victoria E. Wang, Jenny Y. Xue, Dennie T. Frederick, Yi Cao, Eva Lin, Catherine Wilson, Anatoly Urisman, David P. Carbone, Keith T. Flaherty, René Bernards, Piro Lito, Jeff Settleman, Frank McCormick	2019	37
9	RIT1 oncoproteins escape LZTR1-mediated proteolysis Science ·Pau Castel, Alice Cheng, Antonio Cuevas-Navarro, David B. Everman, Alex G. Papageorge, Dhirendra K. Simanshu, Alexandra T. Tankka, Jacqueline Galeas, Anatoly Urisman, Frank McCormick	2019	57
10	Romidepsin Plus Liposomal Doxorubicin Is Safe and Effective in Patients with Relapsed or Refractory T-Cell Lymphoma: Results of a Phase I Dose-Escalation Study Clinical Cancer Research ·Khoan Vu, Murray Elkins, Chen‐Yen Yang, 陈新梅, Kuan Hsu-Chiang, Andréa VENTURA, S E Landrum, Laura B. Pincus, Matthew J. Wieduwilt, Basem M. William, Charalambos Andreadis, Catur Suheri, Frank McCormick, Pierluigi Porcu, Jonathan E. Brammer, Weiyun Z. Ai	2019	33
11	Enhanced MET Translation and Signaling Sustains K-Ras–Driven Proliferation under Anchorage-Independent Growth Conditions Cancer Research ·G. P. Robb, Jacqueline Galeas, Morgan Truitt, Cameron Pitt, Anatoly Urisman, Sourav Bandyopadhyay, Davide Ruggero, Frank McCormick	2015	38
12	Vemurafenib Cooperates with HPV to Promote Initiation of Cutaneous Tumors Cancer Research ·Matthew Holderfield, Edward Lorenzana, Ben Weisburd, S. Nonogaki, Lise Boussemart, Ludovic Lacroix, Gorana Tomasic, Michel Fãvre, Stéphan Vagner, Caroline Robert, Majid Ghoddusi, 由朗坂崎, Nancy Pryer, Frank McCormick, Darrin D. Stuart	2014	20
13	Development of siRNA Payloads to Target KRAS -Mutant Cancer Cancer Discovery ·Tina L. Yuan, Christof Fellmann, Chih-Shia Lee, 資亜利野澤, Vishal Thapar, Liam C. Lee, Dennis Hsu, Danielle Grace, Mele Coleman, Johannes Zuber, Ji Luo, Frank McCormick, Scott W. Lowe	2014	93
14	Epithelial-to-Mesenchymal Transition Rewires the Molecular Path to PI3K-Dependent Proliferation Cancer Discovery ·Megan B. Salt, Sourav Bandyopadhyay, Frank McCormick	2013	85
15	Oncogenic and Wild-type Ras Play Divergent Roles in the Regulation of Mitogen-Activated Protein Kinase Signaling Cancer Discovery ·Amy Young, Peter Berczik, Frank McCormick	2012	163
16	PIK3CA Cooperates with Other Phosphatidylinositol 3′-Kinase Pathway Mutations to Effect Oncogenic Transformation Cancer Research ·Katsutoshi Oda, Sun Liqin, Luika Timmerman, Pablo Rodriguez‐Viciana, David Stokoe, Keiko Shoji, Yuji Taketani, Hiroyuki Kuramoto, Zachary A. Knight, Kevan M. Shokat, Frank McCormick	2008	136
17	Germline Mutations in Genes Within the MAPK Pathway Cause Cardio-facio-cutaneous Syndrome Science ·Pablo Rodriguez‐Viciana, Osamu Tetsu, William E. Tidyman, Anne L. Estep, احمد دایا, Megan Bullock, Frank McCormick, Katherine A. Rauen	2006	418
18	High Frequency of Coexistent Mutations of PIK3CA and PTEN Genes in Endometrial Carcinoma Cancer Research ·Katsutoshi Oda, David Stokoe, Yuji Taketani, Frank McCormick	2005	345
19	SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer Proceedings of the National Academy of Sciences ·Biao He, Liang You, Kazutsugu Uematsu, Keling Zang, Zhidong Xu, Amie Y. Lee, J Costello, Frank McCormick, David M. Jablons	2003	312
20	Transforming Growth Factor Alpha and its Receptor in Human Mammary Epithelial Cells: Modulation of Epidermal Growth Factor Receptor Function with Oncogenic Transformation eScholarship (California Digital Library) ·J. Alexander, Eva M. Valverius, Т. Б. Гершкович, R Clark, Frank McCormick, 愛知県経営者協会, M. E. Lippman, George Atsaves	1989	3

About Frank McCormick

Frank McCormick is a scholar working on Oncology, Molecular Biology, Cell Biology, Biotechnology and Neurology, having authored 381 papers that have together received 57.5k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (125 papers), Cancer-related Molecular Pathways (70 papers), Melanoma and MAPK Pathways (50 papers), PI3K/AKT/mTOR signaling in cancer (48 papers), Virus-based gene therapy research (38 papers), Cell death mechanisms and regulation (32 papers), Wnt/β-catenin signaling in development and cancer (25 papers) and Neurofibromatosis and Schwannoma Cases (25 papers). The work is most often cited by research in Molecular Biology (42.8k citations), Cell Biology (9.3k citations), Oncology (14.4k citations), Cancer Research (5.6k citations) and Immunology and Allergy (2.0k citations). Frank McCormick has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include Osamu Tetsu, Henry R. Bourne, D.A.R. Sanders, Mark S. Boguski, Charles J. Sherr, Meg Trahey, Simon J. Cook, Gideon Bollag, Marc Symons and Dwight V. Nissley. Their work appears in journals such as Molecular and Cellular Biology, Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Science and Oncogene.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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