Lyle W. Ostrow

6.5k total citations · 4 hit papers
33 papers, 2.8k citations indexed

About

Lyle W. Ostrow is a scholar working on Neurology, Molecular Biology and Genetics. According to data from OpenAlex, Lyle W. Ostrow has authored 33 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Neurology, 11 papers in Molecular Biology and 9 papers in Genetics. Recurrent topics in Lyle W. Ostrow's work include Amyotrophic Lateral Sclerosis Research (15 papers), Neurogenetic and Muscular Disorders Research (9 papers) and Nitric Oxide and Endothelin Effects (4 papers). Lyle W. Ostrow is often cited by papers focused on Amyotrophic Lateral Sclerosis Research (15 papers), Neurogenetic and Muscular Disorders Research (9 papers) and Nitric Oxide and Endothelin Effects (4 papers). Lyle W. Ostrow collaborates with scholars based in United States, United Kingdom and Argentina. Lyle W. Ostrow's co-authors include Jeffrey D. Rothstein, Frederick Sachs, Avindra Nath, Timothy M. Miller, Masahiro Fukaya, Shin Hyeok Kang, Ileana Lorenzini, Don W. Cleveland, Dwight E. Bergles and Ying Li and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Communications and Neuron.

In The Last Decade

Lyle W. Ostrow

33 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia

2013 577 citations Timothy M. Miller, Lyle W. Ostrow et al. profile →
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

2013 492 citations Timothy M. Miller, Alan Pestronk et al. The Lancet Neurology profile →
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

2013 449 citations Lyle W. Ostrow, Jeffrey D. Rothstein et al. Nature Neuroscience profile →
Human endogenous retrovirus-K contributes to motor neuron disease

2015 340 citations Andrew L. Mammen, Lyle W. Ostrow et al. Science Translational Medicine profile →

Peers

Lyle W. Ostrow

NEURO

GENET

CMN

NEURO

Fenghua Hu United States

Dhruv Sareen United States

Mary G. Sweeney United Kingdom

Wendy Yang United States

Laura Sánchez Spain

Jennifer C. Moore United States

Rico Laage Germany

Conrad L. Leung United States

Michelle L. Hastings United States

Peter Hackman Finland

Fenghua Hu United States

Lyle W. Ostrow

2.3k ×1.6

1.4k ×1.1

NEURO

387 ×0.5

GENET

466 ×1.0

CMN

429 ×1.2

NEURO

Citations per year, relative to Lyle W. Ostrow Lyle W. Ostrow (= 1×) peers Fenghua Hu

Countries citing papers authored by Lyle W. Ostrow

Since Specialization

Citations

This map shows the geographic impact of Lyle W. Ostrow's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lyle W. Ostrow with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lyle W. Ostrow more than expected).

Fields of papers citing papers by Lyle W. Ostrow

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lyle W. Ostrow. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lyle W. Ostrow. The network helps show where Lyle W. Ostrow may publish in the future.

Co-authorship network of co-authors of Lyle W. Ostrow

This figure shows the co-authorship network connecting the top 25 collaborators of Lyle W. Ostrow. A scholar is included among the top collaborators of Lyle W. Ostrow based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lyle W. Ostrow. Lyle W. Ostrow is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Merler, Michele, Carla Agurto, Marcos A. Trevisan, et al.. (2025). Clinical assessment and interpretation of dysarthria in ALS using attention based deep learning AI models. npj Digital Medicine. 8(1). 260–260. 1 indexed citations

Agurto, Carla, Michele Merler, Marcos A. Trevisan, et al.. (2024). Harnessing Remote Speech Tasks for Early ALS Biomarker Identification. 161–168. 1 indexed citations

Wang, Loo Chien, Jin Zhu, Kathleen Wilsbach, et al.. (2024). TDP43 aggregation at ER-exit sites impairs ER-to-Golgi transport. Nature Communications. 15(1). 9026–9026. 4 indexed citations

Li, Ang, Jianxun Yi, Xuejun Li, et al.. (2024). Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice. eLife. 12. 2 indexed citations

Li, Yini, Xiaoyang Dou, Jun Liu, et al.. (2023). Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration. Nature Neuroscience. 26(8). 1328–1338. 38 indexed citations

Li, Ang, Jianxun Yi, Xuejun Li, et al.. (2023). Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice. eLife. 12. 3 indexed citations

Britson, Kyla A., Jonathan P. Ling, Kerstin E. Braunstein, et al.. (2022). Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis. Science Translational Medicine. 14(628). eabi9196–eabi9196. 34 indexed citations

Wang, Shaopeng, Zhe Zhang, Bo Huang, et al.. (2021). Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD. Nature Communications. 12(1). 4908–4908. 48 indexed citations

Mayer, Jens, Laura Sánchez, Gavin Pereira, et al.. (2018). Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins. Molecular Neurodegeneration. 13(1). 39–39. 47 indexed citations

10.

Pereira, Gavin, Laura Sánchez, Paul Schaughency, et al.. (2018). Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis. Mobile DNA. 9(1). 35–35. 38 indexed citations

11.

Antinone, Sarah E., Ghanashyam D. Ghadge, Lyle W. Ostrow, Raymond P. Roos, & William N. Green. (2017). S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects. Scientific Reports. 7(1). 41141–41141. 17 indexed citations

12.

Ayers, Jacob I., Susan Fromholt, Ahmad Galaleldeen, et al.. (2016). Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS. Acta Neuropathologica. 132(6). 827–840. 38 indexed citations

13.

Lamitina, Todd, Nicole F. Liachko, Mariangela Sabatella, et al.. (2015). Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance. Journal of Neuroscience. 35(42). 14286–14306. 20 indexed citations

14.

Miller, Timothy M., Alan Pestronk, William David, et al.. (2013). An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study. The Lancet Neurology. 12(5). 435–442. 492 indexed citations breakdown →

15.

Ostrow, Lyle W., Andrea M. Corse, Brett M. Morrison, et al.. (2012). Expanding the spectrum of monoclonal light chain deposition disease in muscle. Muscle & Nerve. 45(5). 755–761. 13 indexed citations

16.

Williams, Kirsten M., Lyle W. Ostrow, David M. Loeb, et al.. (2011). Immunohistochemistry of affected tissue may guide cGVHD treatment decisions. Bone Marrow Transplantation. 47(5). 731–733. 4 indexed citations

17.

Tan, Kevin, et al.. (2009). PML-IRIS in patients with HIV infection. Neurology. 72(17). 1458–1464. 259 indexed citations

18.

Gottlieb, Philip A., Thomas M. Suchyna, Lyle W. Ostrow, & Frederick Sachs. (2004). Mechanosensitive Ion Channels as Drug Targets. PubMed. 3(4). 287–295. 36 indexed citations

19.

Ostrow, Lyle W. & Frederick Sachs. (2004). Mechanosensation and endothelin in astrocytes—hypothetical roles in CNS pathophysiology. Brain Research Reviews. 48(3). 488–508. 78 indexed citations

20.

Ostrow, Lyle W., Thomas J. Langan, & Frederick Sachs. (2000). Stretch-Induced Endothelin-1 Production by Astrocytes. Journal of Cardiovascular Pharmacology. 36(Supplement 1). S274–S277. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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