Frederick Sachs

19.2k total citations · 3 hit papers
201 papers, 14.8k citations indexed

About

Frederick Sachs is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Physiology. According to data from OpenAlex, Frederick Sachs has authored 201 papers receiving a total of 14.8k indexed citations (citations by other indexed papers that have themselves been cited), including 137 papers in Molecular Biology, 59 papers in Cellular and Molecular Neuroscience and 55 papers in Physiology. Recurrent topics in Frederick Sachs's work include Ion channel regulation and function (107 papers), Erythrocyte Function and Pathophysiology (47 papers) and Cardiac electrophysiology and arrhythmias (33 papers). Frederick Sachs is often cited by papers focused on Ion channel regulation and function (107 papers), Erythrocyte Function and Pathophysiology (47 papers) and Cardiac electrophysiology and arrhythmias (33 papers). Frederick Sachs collaborates with scholars based in United States, China and Japan. Frederick Sachs's co-authors include Philip A. Gottlieb, Thomas M. Suchyna, Chilman Bae, Anthony Auerbach, Fanjie Meng, Wade J. Sigurdson, Sergei Sukharev, A. Ruknudin, Hai Hu and Radhakrishnan Gnanasambandam and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Frederick Sachs

200 papers receiving 14.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Stretch‐activated single ion channel currents in tissue‐cultured embryonic chick skeletal muscle.

1984 760 citations Frederick Sachs et al. profile →
Block of Stretch-Activated Ion Channels in Xenopus Oocytes by Gadolinium and Calcium Ions

1989 722 citations Frederick Sachs et al. profile →
Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

2016 380 citations Lynn Ziegler, Frederick Sachs et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Frederick Sachs United States	68	9.7k	4.7k	3.4k	2.6k	2.4k	201	14.8k
Avril V. Somlyo United States	68	12.1k 1.3×	4.5k 1.0×	2.7k 0.8×	4.3k 1.7×	3.3k 1.4×	196	18.1k
Boris Martinac Australia	55	10.0k 1.0×	5.3k 1.1×	1.8k 0.5×	617 0.2×	1.9k 0.8×	228	13.5k
David P. Corey United States	77	8.9k 0.9×	2.6k 0.5×	6.1k 1.8×	1.4k 0.5×	1.5k 0.6×	151	19.8k
James T. Stull United States	70	10.1k 1.0×	2.6k 0.6×	1.4k 0.4×	5.8k 2.2×	3.3k 1.4×	209	15.0k
Michael J. Davis United States	64	4.4k 0.5×	4.5k 0.9×	1.8k 0.5×	3.6k 1.4×	1.5k 0.6×	252	13.4k
Masahiro Sokabe Japan	55	4.6k 0.5×	1.8k 0.4×	1.5k 0.5×	591 0.2×	2.4k 1.0×	252	9.5k
Owen P. Hamill United States	31	17.7k 1.8×	2.4k 0.5×	13.2k 3.9×	5.1k 2.0×	1.1k 0.4×	65	22.0k
Vann Bennett United States	91	13.9k 1.4×	9.9k 2.1×	5.9k 1.7×	2.8k 1.1×	7.3k 3.0×	218	24.3k
Robert Adelstein United States	80	12.0k 1.2×	1.5k 0.3×	1.6k 0.5×	5.6k 2.2×	8.1k 3.4×	206	19.6k
Peter Lipp Germany	52	10.0k 1.0×	1.5k 0.3×	4.6k 1.4×	2.9k 1.1×	1.7k 0.7×	189	14.9k

Countries citing papers authored by Frederick Sachs

Since Specialization

Citations

This map shows the geographic impact of Frederick Sachs's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frederick Sachs with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frederick Sachs more than expected).

Fields of papers citing papers by Frederick Sachs

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frederick Sachs. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frederick Sachs. The network helps show where Frederick Sachs may publish in the future.

Co-authorship network of co-authors of Frederick Sachs

This figure shows the co-authorship network connecting the top 25 collaborators of Frederick Sachs. A scholar is included among the top collaborators of Frederick Sachs based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frederick Sachs. Frederick Sachs is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Pak, On Shun, et al.. (2023). Effects of membrane viscoelasticity on the red blood cell dynamics in a microcapillary. Biophysical Journal. 122(11). 2230–2241. 10 indexed citations

Gottlieb, Philip A., et al.. (2019). Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells. Journal of Cell Science. 132(11). 49 indexed citations

Maneshi, Mohammad Mehdi, Lynn Ziegler, Frederick Sachs, Susan Z. Hua, & Philip A. Gottlieb. (2018). Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1. Scientific Reports. 8(1). 14267–14267. 62 indexed citations

Suchyna, Thomas M., Fanjie Meng, Frederick Sachs, & Wilma A. Hofmann. (2018). Nuclear Lamina Stress Measured with FRET Based Stress Sensor. Biophysical Journal. 114(3). 513a–513a. 2 indexed citations

Shi, Xiangyan, Dian Xu, Chengchen Guo, et al.. (2018). Investigating the interaction of Grammostola rosea venom peptides and model lipid bilayers with solid-state NMR and electron microscopy techniques. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1861(1). 151–160. 3 indexed citations

Han, Huazhi, Avia Rosenhouse‐Dantsker, Radhakrishnan Gnanasambandam, Frederick Sachs, & Irena Levitan. (2016). Cross-Talk between Cholesterol, PIP2 and Caveolin in Regulating Kir2 Channels. Biophysical Journal. 110(3). 608a–608a. 1 indexed citations

Lee, Whasil, Holly A. Leddy, Yong Chen, et al.. (2014). Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proceedings of the National Academy of Sciences. 111(47). E5114–22. 352 indexed citations

Guo, Jun, et al.. (2013). Fluorescence-Based Force/Tension Sensors: A Novel Tool to Visualize Mechanical Forces in Structural Proteins in Live Cells. Antioxidants and Redox Signaling. 20(6). 986–999. 48 indexed citations

Gnanasambandam, Radhakrishnan, Kazuhisa Nishizawa, Frederick Sachs, & Thomas M. Suchyna. (2013). Positively Charged Residues on GsMTx4 are Crucial for Inhibition of the Mechanosensitive Ion Channel Piezo1. Biophysical Journal. 104(2). 467a–467a. 2 indexed citations

10.

Sukharev, Sergei & Frederick Sachs. (2012). Molecular force transduction by ion channels – diversity and unifying principles. Journal of Cell Science. 125(Pt 13). 3075–83. 125 indexed citations

11.

Meng, Fanjie & Frederick Sachs. (2011). Investigating the Mechanical Forces in Non Erythrocytic Spectrin with a New Force Sensor. Biophysical Journal. 100(3). 304a–304a. 1 indexed citations

12.

Meng, Fanjie, Thomas M. Suchyna, & Frederick Sachs. (2010). Real Time Detection of Mechanical Stress in Specific Cytoskeletal Proteins. Biophysical Journal. 98(3). 753a–753a. 1 indexed citations

13.

Kamaraju, Kishore, Philip A. Gottlieb, Frederick Sachs, & Sergei Sukharev. (2010). Effects of GsMTx4 on Bacterial Mechanosensitive Channels in Inside-Out Patches from Giant Spheroplasts. Biophysical Journal. 99(9). 2870–2878. 37 indexed citations

14.

Suchyna, Thomas M., Vladislav S. Markin, & Frederick Sachs. (2009). Biophysics and Structure of the Patch and the Gigaseal. Biophysical Journal. 97(3). 738–747. 148 indexed citations

15.

Bowman, Charles L., et al.. (2006). Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: History, properties, mechanisms and pharmacology. Toxicon. 49(2). 249–270. 151 indexed citations

16.

Köhl, Peter, Frederick Sachs, & Michael R. Franz. (2005). Cardiac mechano-electric feedback and arrhythmias : from pipette to patient. Elsevier eBooks. 53 indexed citations

17.

Li, Bao, Frederick Sachs, & Gerhard Dahl. (2004). Connexins are mechanosensitive. American Journal of Physiology-Cell Physiology. 287(5). C1389–C1395. 134 indexed citations

18.

Zhang, Pingcheng, A.M. Keleshian, & Frederick Sachs. (2001). Voltage-induced membrane movement. Nature. 413(6854). 428–432. 173 indexed citations

19.

Qin, Feng, Anthony Auerbach, & Frederick Sachs. (2000). A Direct Optimization Approach to Hidden Markov Modeling for Single Channel Kinetics. Biophysical Journal. 79(4). 1915–1927. 166 indexed citations

20.

Sachs, Frederick. (1987). Baroreceptor mechanisms at the cellular level.. PubMed. 46(1). 12–6. 81 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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