C. Frank Bennett

46.7k total citations · 23 hit papers
227 papers, 30.1k citations indexed

About

C. Frank Bennett is a scholar working on Molecular Biology, Genetics and Cellular and Molecular Neuroscience. According to data from OpenAlex, C. Frank Bennett has authored 227 papers receiving a total of 30.1k indexed citations (citations by other indexed papers that have themselves been cited), including 183 papers in Molecular Biology, 55 papers in Genetics and 36 papers in Cellular and Molecular Neuroscience. Recurrent topics in C. Frank Bennett's work include Neurogenetic and Muscular Disorders Research (53 papers), RNA Interference and Gene Delivery (52 papers) and RNA Research and Splicing (48 papers). C. Frank Bennett is often cited by papers focused on Neurogenetic and Muscular Disorders Research (53 papers), RNA Interference and Gene Delivery (52 papers) and RNA Research and Splicing (48 papers). C. Frank Bennett collaborates with scholars based in United States, Canada and United Kingdom. C. Frank Bennett's co-authors include Eric E. Swayze, Frank Rigo, Stanley T. Crooke, Adrian R. Krainer, Susan M. Freier, Yimin Hua, Brenda F. Baker, Gene Hung, Daniel A. Norris and Don W. Cleveland and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

C. Frank Bennett

224 papers receiving 29.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

2010 1.7k citations C. Frank Bennett et al. profile →
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

2006 1.7k citations C. Frank Bennett et al. profile →
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

2010 1.1k citations C. Frank Bennett et al. profile →
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

2011 959 citations C. Frank Bennett, Don W. Cleveland et al. profile →
MicroRNA-143 Regulates Adipocyte Differentiation

2004 831 citations Eric G. Marcusson, Seongjoon Koo et al. Journal of Biological Chemistry profile →
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study

2016 736 citations Richard S. Finkel, Claudia A. Chiriboga et al. profile →
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

2013 670 citations Frank Rigo, C. Frank Bennett et al. Neuron profile →
Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides

2015 647 citations C. Frank Bennett et al. profile →
RNA-Targeted Therapeutics

2018 612 citations Stanley T. Crooke, C. Frank Bennett et al. profile →
Regulating Gene Expression through RNA Nuclear Retention

2005 569 citations C. Frank Bennett et al. profile →
Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

2012 563 citations Gene Hung, C. Frank Bennett et al. Neuron profile →
Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

2011 556 citations Yimin Hua, Kentaro Sahashi et al. Nature profile →
Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

1999 526 citations C. Frank Bennett et al. profile →
Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides.

1992 525 citations C. Frank Bennett et al. profile →
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model

2010 501 citations Yimin Hua, Kentaro Sahashi et al. profile →
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion

2013 493 citations Frank Rigo, C. Frank Bennett et al. profile →
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

2013 492 citations Timothy M. Miller, C. Frank Bennett et al. profile →
Results from a phase 1 study of nusinersen (ISIS-SMN _Rx ) in children with spinal muscular atrophy

2016 460 citations Claudia A. Chiriboga, Basil T. Darras et al. profile →
Therapeutic Antisense Oligonucleotides Are Coming of Age

2019 416 citations C. Frank Bennett profile →
Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

2014 378 citations Seung Chun, C. Frank Bennett et al. Nature profile →
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy

2017 362 citations Sarah L. DeVos, C. Frank Bennett et al. profile →
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration

2019 339 citations C. Frank Bennett, Frank Rigo et al. profile →
Antisense Oligonucleotide Therapies for Neurodegenerative Diseases

2019 242 citations C. Frank Bennett, Adrian R. Krainer et al. Annual Review of Neuroscience profile →

Peers

Countries citing papers authored by C. Frank Bennett

Since Specialization

Citations

This map shows the geographic impact of C. Frank Bennett's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. Frank Bennett with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. Frank Bennett more than expected).

Fields of papers citing papers by C. Frank Bennett

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. Frank Bennett. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. Frank Bennett. The network helps show where C. Frank Bennett may publish in the future.

Co-authorship network of co-authors of C. Frank Bennett

This figure shows the co-authorship network connecting the top 25 collaborators of C. Frank Bennett. A scholar is included among the top collaborators of C. Frank Bennett based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with C. Frank Bennett. C. Frank Bennett is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Tool to Resolve Distortions in Elemental and Isotopic Imaging 2024 ·Journal of the American Chemical Society ·(unknown), Chen Gu, Wenxin Song, Kai Chen, (unknown), Mehran Nikan, Paul Guagliardo, C. Frank Bennett, Punit P. Seth, K. Swaminathan Iyer, Stephen G. Young, Xiaojuan Qi, Haibo Jiang	0
2	Antisense drugs for rare and ultra-rare genetic neurological diseases 2023 ·Neuron ·(unknown), C. Frank Bennett	9
3	Long-Term SMN- and Ncald-ASO Combinatorial Therapy in SMA Mice and NCALD-ASO Treatment in hiPSC-Derived Motor Neurons Show Protective Effects 2023 ·International Journal of Molecular Sciences ·(unknown), (unknown), Karen Ling, (unknown), Frank Rigo, C. Frank Bennett, Brunhilde Wirth	7
4	ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth 2021 ·Cancer Research ·Wai Kit, (unknown), Juergen Scharner, Ana S.H. Costa, Kuan‐Ting Lin, Hyun Yong Jeon, John E. Wilkinson, Michaela Jackson, Frank Rigo, C. Frank Bennett, Adrian R. Krainer	79
5	Antisense Oligonucleotide Therapies for Neurodegenerative Diseases breakdown → 2019 ·Annual Review of Neuroscience ·C. Frank Bennett, Adrian R. Krainer, Don W. Cleveland	242
6	SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage 2017 ·Proceedings of the National Academy of Sciences ·Mohini Jangi, Christina Fleet, Patrick Cullen, (unknown), Shila Mekhoubad, Eric Chiao, Norm Allaire, C. Frank Bennett, Frank Rigo, Adrian R. Krainer, Jessica A. Hurt, John P. Carulli, John F. Staropoli	91
7	Efficacy and safety of nusinersen in children with later-onset spinal muscular atrophy (SMA): results of the phase 3 CHERISH study 2017 ·Neuropediatrics ·Janbernd Kirschner, Eugenio Mercuri, Richard S. Finkel, Claudia A. Chiriboga, Nancy L. Kuntz, Basil T. Darras, Perry B. Shieh, Kayoko Saito, Darryl C. De Vivo, Elena Mazzone, Jacqueline Montes, Qingqing Yang, Zhenshao Zhong, Sarah Gheuens, C. Frank Bennett, Eugene Schneider, Wildon Farwell	0
8	Effects on Murine Behavior and Lifespan of Selectively Decreasing Expression of Mutant Huntingtin Allele by Supt4h Knockdown 2015 ·PLoS Genetics ·(unknown), Yijuang Chern, (unknown), (unknown), (unknown), Seung Chun, Frank Rigo, C. Frank Bennett, Ning Deng, Yanan Feng, Chyuan‐Sheng Lin, Yu‐Ting Yan, Stanley N. Cohen, Tzu‐Hao Cheng	40
9	DICER/AGO-dependent epigenetic silencing of D4Z4 repeats enhanced by exogenous siRNA suggests mechanisms and therapies for FSHD 2015 ·Human Molecular Genetics ·(unknown), Lauren Snider, Zizhen Yao, Rabi Tawil, Silvère M. van der Maarel, Frank Rigo, C. Frank Bennett, Galina N. Filippova, Stephen J. Tapscott	40
10	Antisense Reduction of Tau in Adult Mice Protects against Seizures 2013 ·Journal of Neuroscience ·Sarah L. DeVos, (unknown), Guojun Chen, (unknown), Kaoru Yamada, Floy R. Stewart, Dorothy R. Schuler, Susan E. Maloney, David F. Wozniak, Frank Rigo, C. Frank Bennett, John R. Cirrito, David M. Holtzman, Timothy M. Miller	250
11	Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing 2012 ·Nature Chemical Biology ·Frank Rigo, Yimin Hua, Seung Chun, Thazha P. Prakash, Adrian R. Krainer, C. Frank Bennett	89
12	Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model breakdown → 2011 ·Nature ·Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung, Guy Horev, C. Frank Bennett, Adrian R. Krainer	556
13	hsa-miR-191 Is a Candidate Oncogene Target for Hepatocellular Carcinoma Therapy 2010 ·Cancer Research ·Eran Elyakim, Einat Sitbon, Alexander Faerman, Sarit Tabak, (unknown), (unknown), Avital Dov, Eric G. Marcusson, C. Frank Bennett, Ayelet Chajut, Dalia Cohen, Noga Yerushalmi	126
14	Defining the transcriptome of accelerated and replicatively senescent keratinocytes reveals links to differentiation, interferon signaling, and Notch related pathways 2006 ·Journal of Cellular Biochemistry ·Ranjan J. Perera, Seongjoon Koo, C. Frank Bennett, Nicholas M. Dean, Nitin Gupta, Jian‐Zhong Qin, Brian J. Nickoloff	10
15	A Constitutive Cytoprotective Pathway Protects Endothelial Cells from Lipopolysaccharide-induced Apoptosis 2001 ·Journal of Biological Chemistry ·Douglas D. Bannerman, Joan C. Tupper, William A. Ricketts, C. Frank Bennett, Robert K. Winn, John M. Harlan	98
16	Intercellular Adhesion Molecule-1 Suppression in Skin by Topical Delivery of Anti-Sense Oligonucleotides 2000 ·Journal of Investigative Dermatology ·Rahul Mehta, (unknown), Scott Cooper, Michael V. Templin, Ya-Li Tsai, Thomas P. Condon, C. Frank Bennett, Gregory E. Hardee	37
17	Antisense oligonucleotides to the epidermal growth factor receptor 1999 ·Breast Cancer Research and Treatment ·Lois Witters, Rakesh Kumar, Mahitosh Mandal, C. Frank Bennett, Loren Miraglia, Allan Lipton	31
18	Effect of ICAM-1/1FA-1 blockade on pancreatic islet allograft survival, function, and early cytokine production 1997 ·Transplantation Proceedings ·Steven M. Katz, Ling Tian, S M Stepkowski, (unknown), C. Frank Bennett, B D Kahan	7
19	Expression of human group II PLA2 in transgenic mice results in epidermal hyperplasia in the absence of inflammatory infiltrate. 1996 ·Journal of Clinical Investigation ·David Grass, (unknown), (unknown), (unknown), Timo J. Nevalainen, C. Frank Bennett, Mark E. Swanson	150
20	Phosphorylation of PI-specific phospholipase C by protein kinase C in vivo 1987 ·Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States) ·C. Frank Bennett, (unknown), Stanley T. Crooke	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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