Lorenzo M. Refolo

4.3k total citations · 1 hit paper
41 papers, 3.4k citations indexed

About

Lorenzo M. Refolo is a scholar working on Physiology, Molecular Biology and Computational Theory and Mathematics. According to data from OpenAlex, Lorenzo M. Refolo has authored 41 papers receiving a total of 3.4k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Physiology, 16 papers in Molecular Biology and 9 papers in Computational Theory and Mathematics. Recurrent topics in Lorenzo M. Refolo's work include Alzheimer's disease research and treatments (26 papers), Computational Drug Discovery Methods (9 papers) and Endoplasmic Reticulum Stress and Disease (5 papers). Lorenzo M. Refolo is often cited by papers focused on Alzheimer's disease research and treatments (26 papers), Computational Drug Discovery Methods (9 papers) and Endoplasmic Reticulum Stress and Disease (5 papers). Lorenzo M. Refolo collaborates with scholars based in United States, United Kingdom and Spain. Lorenzo M. Refolo's co-authors include Miguel A. Pappolla, Karen Duff, Brian Malester, Kumar Sambamurti, John J. LaFrancois, Tara Bryant‐Thomas, G S Tint, Suzana Petanceska, Rong Wang and Nikolaos K. Robakis and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The EMBO Journal.

In The Last Decade

Lorenzo M. Refolo

41 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

2000 825 citations Lorenzo M. Refolo, Miguel A. Pappolla et al. Neurobiology of Disease profile →

Peers

Countries citing papers authored by Lorenzo M. Refolo

Since Specialization

Citations

This map shows the geographic impact of Lorenzo M. Refolo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lorenzo M. Refolo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lorenzo M. Refolo more than expected).

Fields of papers citing papers by Lorenzo M. Refolo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lorenzo M. Refolo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lorenzo M. Refolo. The network helps show where Lorenzo M. Refolo may publish in the future.

Co-authorship network of co-authors of Lorenzo M. Refolo

This figure shows the co-authorship network connecting the top 25 collaborators of Lorenzo M. Refolo. A scholar is included among the top collaborators of Lorenzo M. Refolo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lorenzo M. Refolo. Lorenzo M. Refolo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Optimizing the use of CROs by academia and small companies 2013 ·Nature Reviews Drug Discovery ·Rachel Lane, Lauren G. Friedman, Curtis T. Keith, Steven P. Braithwaite, Julie A. Frearson, (unknown), Frank M. Longo, Lorenzo M. Refolo, D. Martin Watterson, Katya Tsaioun, Diana W. Shineman, Howard Fillit	2
2	NIA Commentary: Translational Issues in Alzheimer’s Disease Drug Development 2011 ·Neuropsychopharmacology ·Neil Buckholtz, Laurie Ryan, Suzana Petanceska, Lorenzo M. Refolo	6
3	Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies 2011 ·Alzheimer s Research & Therapy ·Diana W. Shineman, Guriqbal S. Basi, Jennifer L. Bizon, Carol A. Colton, Barry Greenberg, Beth Hollister, John Lincecum, Gabrielle G. Leblanc, (unknown), Feng Luo, Dave Morgan, (unknown), Lorenzo M. Refolo, David Riddell, Kimberly Scearce‐Levie, Patrick Sweeney, Juha Yrjänheikki, Howard Fillit	104
4	Partnerships Between Philanthropy, Government and Investors are Needed to Advance Drug Discovery for Neurodegenerative Diseases 2006 ·Current Alzheimer Research ·Lorenzo M. Refolo, Howard Fillit	5
5	Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid β peptide levels 2006 ·Neurobiology of Disease ·Javier Pacheco‐Quinto, Elena Turco, Steven DeRosa, (unknown), Felix Cruz-Sánchez, Kumar Sambamurti, Lorenzo M. Refolo, Suzana Petanceska, Miguel A. Pappolla	100
6	Apolipoprotein E4 as a Target for Developing New Therapeutics for Alzheimer's Disease 2004 ·Journal of Molecular Neuroscience ·Lorenzo M. Refolo, Howard Fillit	15
7	Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease 2003 ·Journal of Neurochemistry ·Etsuro Matsubara, Tara Bryant‐Thomas, (unknown), Tracey L. Henry, Burkhard Pöeggeler, Donald E. Herbert, Felix Cruz-Sánchez, (unknown), Mark A. Smith, George Perry, Mikio Shoji, Kōji Abe, Anna Leone, (unknown), (unknown), Jorge Ghiso, Christina Williams, Lorenzo M. Refolo, Miguel A. Pappolla	275
8	Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology 2003 ·Neurology ·Miguel A. Pappolla, Tara Bryant‐Thomas, David Herbert, J. Pacheco, Marcos F Garcia, (unknown), Xavier Gironès, Tracey L. Henry, E. Matsubara, Daniel Zambón, Benjamin Wolozin, Mary Sano, F. F. Cruz-Sánchez, L. J. Thal, Suzana Petanceska, Lorenzo M. Refolo	258
9	Cholesterol, oxidative stress, and Alzheimer’s disease: expanding the horizons of pathogenesis1 1This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal. 2002 ·Free Radical Biology and Medicine ·Miguel A. Pappolla, Mark A. Smith, Tara Bryant‐Thomas, (unknown), Suzana Petanceska, George Perry, Leon J. Thal, Mary Sano, Lorenzo M. Refolo	68
10	Statin therapy for Alzheimer’s disease 2002 ·Journal of Molecular Neuroscience ·Suzana Petanceska, Steven DeRosa, Vicki Olm, Nichole Diaz, Ali Sharma, (unknown), Karen Duff, Miguel A. Pappolla, Lorenzo M. Refolo	129
11	A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease 2001 ·Neurobiology of Disease ·Lorenzo M. Refolo, Miguel A. Pappolla, John J. LaFrancois, Brian Malester, Stephen D. Schmidt, (unknown), G S Tint, (unknown), Marc Mercken, Suzana Petanceska, Karen Duff	441
12	Modulation of Aβ peptides by estrogen in mouse models 2001 ·Journal of Neurochemistry ·Hui Zheng, Huaxi Xu, Sacha Uljon, Rachel S. Gross, (unknown), James S. Gaynor, John J. LaFrancois, James Simpkins, Lorenzo M. Refolo, Suzana Petanceska, (unknown), Karen Duff	143
13	Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model breakdown → 2000 ·Neurobiology of Disease ·Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester, John J. LaFrancois, Tara Bryant‐Thomas, Rong Wang, G S Tint, Kumar Sambamurti, Karen Duff	825
14	Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization 1995 ·Journal of Neuroscience Research ·Lorenzo M. Refolo, Kumar Sambamurti, Spiros Efthimiopoulos, Miguel A. Pappolla, Nikolaos K. Robakis	51
15	Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins 1995 ·Neuroscience Letters ·Miguel A. Pappolla, Kumar Sambamurti, Spiros Efthimiopoulos, Lorenzo M. Refolo, Rosmarıa Omar, N.K. Robakis	7
16	Study of the phorbol ester effect on Alzheimer amyloid precursor processing: Sequence requirements and involvement of a Cholera toxin sensitive protein 1994 ·Journal of Neuroscience Research ·Spiros Efthimiopoulos, Kevin M. Felsenstein, Kumar Sambamurti, Nikolaos K. Robakis, Lorenzo M. Refolo	29
17	Altered expression and phosphorylation of amyloid precursor protein in heat shocked neuronal PC12 cells 1993 ·Molecular Brain Research ·(unknown), Lorenzo M. Refolo, Carl R. Merril, William Wallace	14
18	Reversible phosphorylation of tau to form A68 in heat-shocked neuronal PC12 cells 1993 ·Molecular Brain Research ·William Wallace, (unknown), J. Sugár, Carl R. Merril, Lorenzo M. Refolo	14
19	The Alzheimer's Amyloid Precursor Is Cleaved Intracellularly in the Trans‐Golgi Network or in a Post‐Golgi Compartment ^a 1992 ·Annals of the New York Academy of Sciences ·Kumar Sambamurti, Lorenzo M. Refolo, Junichi Shioi, Miguel A. Pappolla, Nikolaos K. Robakis	22
20	The Alzheimer's amyloid precursor protein is produced by type I astrocytes in primary cultures of rat neuroglia 1990 ·Journal of Neuroscience Research ·F. Berkenbosch, Lorenzo M. Refolo, Victor L. Friedrich, Diana Casper, Mariann Blum, Nikolaos K. Robakis	51

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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