Julie A. Frearson

3.8k total citations · 1 hit paper
43 papers, 2.2k citations indexed

About

Julie A. Frearson is a scholar working on Molecular Biology, Epidemiology and Public Health, Environmental and Occupational Health. According to data from OpenAlex, Julie A. Frearson has authored 43 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 23 papers in Epidemiology and 18 papers in Public Health, Environmental and Occupational Health. Recurrent topics in Julie A. Frearson's work include Trypanosoma species research and implications (23 papers), Research on Leishmaniasis Studies (15 papers) and Biochemical and Molecular Research (9 papers). Julie A. Frearson is often cited by papers focused on Trypanosoma species research and implications (23 papers), Research on Leishmaniasis Studies (15 papers) and Biochemical and Molecular Research (9 papers). Julie A. Frearson collaborates with scholars based in United Kingdom, Norway and United States. Julie A. Frearson's co-authors include Paul G. Wyatt, Ian H. Gilbert, Denis R. Alexander, Ruth Brenk, Alan H. Fairlamb, Alessandro Schipani, Iain T. Collie, Emma Shanks, Deuan C. Jones and Irene Hallyburton and has published in prestigious journals such as Journal of Biological Chemistry, The Journal of Experimental Medicine and PLoS ONE.

In The Last Decade

Julie A. Frearson

43 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases

2007 482 citations Ruth Brenk, Ian H. Gilbert et al. ChemMedChem profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Julie A. Frearson United Kingdom	25	998	723	714	707	373	43	2.2k
Kohei Yokoyama United States	30	1.5k 1.5×	510 0.7×	389 0.5×	754 1.1×	250 0.7×	68	2.6k
Simon A. Osborne United Kingdom	20	628 0.6×	425 0.6×	416 0.6×	360 0.5×	165 0.4×	42	1.5k
Roberta Ettari Italy	27	991 1.0×	494 0.7×	447 0.6×	742 1.0×	204 0.5×	93	2.1k
Bryan T. Mott United States	22	1.3k 1.3×	316 0.4×	284 0.4×	370 0.5×	284 0.8×	44	2.1k
Anang A. Shelat United States	30	1.7k 1.7×	375 0.5×	354 0.5×	447 0.6×	417 1.1×	82	2.9k
S.K. Puri India	31	720 0.7×	878 1.2×	180 0.3×	1.5k 2.2×	276 0.7×	95	2.9k
Robert T. Jacobs United States	27	755 0.8×	413 0.6×	515 0.7×	625 0.9×	100 0.3×	43	1.9k
Arnulf Dorn Switzerland	19	1.0k 1.0×	1.1k 1.5×	137 0.2×	494 0.7×	438 1.2×	27	2.4k
Richard J. Sciotti United States	25	537 0.5×	543 0.8×	347 0.5×	623 0.9×	95 0.3×	48	1.6k
Yew Mun Lee Singapore	20	825 0.8×	362 0.5×	235 0.3×	237 0.3×	211 0.6×	33	1.7k

Countries citing papers authored by Julie A. Frearson

Since Specialization

Citations

This map shows the geographic impact of Julie A. Frearson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Julie A. Frearson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Julie A. Frearson more than expected).

Fields of papers citing papers by Julie A. Frearson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Julie A. Frearson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Julie A. Frearson. The network helps show where Julie A. Frearson may publish in the future.

Co-authorship network of co-authors of Julie A. Frearson

This figure shows the co-authorship network connecting the top 25 collaborators of Julie A. Frearson. A scholar is included among the top collaborators of Julie A. Frearson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Julie A. Frearson. Julie A. Frearson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Harrison, Justin R., Stephen Brand, Victoria Smith, et al.. (2018). A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N -Myristoyltransferase Inhibitors. Journal of Medicinal Chemistry. 61(18). 8374–8389. 46 indexed citations

Bayliss, Tracy, David A. Robinson, Victoria Smith, et al.. (2017). Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors. Journal of Medicinal Chemistry. 60(23). 9790–9806. 16 indexed citations

Hallyburton, Irene, Raffaella Grimaldi, Andrew Woodland, et al.. (2017). Screening a protein kinase inhibitor library against Plasmodium falciparum. Malaria Journal. 16(1). 446–446. 16 indexed citations

Rycker, Manu De, Irene Hallyburton, John Thomas, et al.. (2013). Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay. Antimicrobial Agents and Chemotherapy. 57(7). 2913–2922. 108 indexed citations

Woodland, Andrew, Raffaella Grimaldi, Torsten Luksch, et al.. (2013). From On‐Target to Off‐Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti‐Trypanosoma brucei Drug Discovery Lead Molecules. ChemMedChem. 8(7). 1127–1137. 22 indexed citations

Lane, Rachel, Lauren G. Friedman, Curtis T. Keith, et al.. (2013). Optimizing the use of CROs by academia and small companies. Nature Reviews Drug Discovery. 12(7). 487–488. 2 indexed citations

Gardiner, Mary, Stuart P. McElroy, Daniel James, et al.. (2012). Assessment of Pseudomonas aeruginosa N5,N10-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target. PLoS ONE. 7(4). e35973–e35973. 18 indexed citations

Spinks, Daniel, Leah S. Torrie, Stephen Thompson, et al.. (2011). Design, Synthesis and Biological Evaluation of Trypanosoma brucei Trypanothione Synthetase Inhibitors. ChemMedChem. 7(1). 95–106. 36 indexed citations

Smith, Victoria, Laura A. T. Cleghorn, Andrew Woodland, et al.. (2011). Optimisation of the Anti‐Trypanosoma brucei Activity of the Opioid Agonist U50488. ChemMedChem. 6(10). 1832–1840. 6 indexed citations

10.

Gilbert, Ian H., Didier Leroy, & Julie A. Frearson. (2011). Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?. Current Topics in Medicinal Chemistry. 11(10). 1284–1291. 19 indexed citations

11.

Spinks, Daniel, Han B. Ong, Chidochangu P. Mpamhanga, et al.. (2010). Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1. ChemMedChem. 6(2). 302–308. 32 indexed citations

12.

Ma, Jiangtao, Corinna Benz, Raffaella Grimaldi, et al.. (2010). Nuclear DBF-2-related Kinases Are Essential Regulators of Cytokinesis in Bloodstream Stage Trypanosoma brucei. Journal of Biological Chemistry. 285(20). 15356–15368. 29 indexed citations

13.

Jones, Deuan C., Irene Hallyburton, Laste Stojanovski, et al.. (2010). Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis. Biochemical Pharmacology. 80(10). 1478–1486. 56 indexed citations

14.

Schüttelkopf, Alexander W., et al.. (2010). Acetazolamide-based fungal chitinase inhibitors. Bioorganic & Medicinal Chemistry. 18(23). 8334–8340. 42 indexed citations

15.

Frearson, Julie A. & Iain T. Collie. (2009). HTS and hit finding in academia – from chemical genomics to drug discovery. Drug Discovery Today. 14(23-24). 1150–1158. 64 indexed citations

16.

Shanks, Emma, Han B. Ong, David A. Robinson, et al.. (2009). Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductase. Analytical Biochemistry. 396(2). 194–203. 18 indexed citations

17.

Patterson, Stephen, Deuan C. Jones, Emma Shanks, et al.. (2009). Synthesis and Evaluation of 1‐(1‐(Benzo[b]thiophen‐2‐yl)cyclohexyl)piperidine (BTCP) Analogues as Inhibitors of Trypanothione Reductase. ChemMedChem. 4(8). 1341–1353. 42 indexed citations

18.

Frearson, Julie A., Paul G. Wyatt, Ian H. Gilbert, & Alan H. Fairlamb. (2007). Target assessment for antiparasitic drug discovery. Trends in Parasitology. 23(12). 589–595. 108 indexed citations

19.

Frearson, Julie A. & Denis R. Alexander. (1997). The role of phosphotyrosine phosphatases in haematopoietic cell signal transduction. BioEssays. 19(5). 417–427. 59 indexed citations

20.

Frearson, Julie A., Taolin Yi, & Denis R. Alexander. (1996). A tyrosine‐phosphorylated 110–120‐kDa protein associates with the C‐terminal SH2 domain of phosphotyrosine phosphatase‐1D in T cell receptor‐stimulated T cells. European Journal of Immunology. 26(7). 1539–1543. 21 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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