Julie A. Frearson

3.8k citations

43 papers · 2.2k indexed · 1 hit paper · h-index 25

Public Health, Environmental and Occupational Health top 2%
- Research on Leishmaniasis Studies 15
Organic Chemistry top 5%
- Synthesis and Biological Evaluation 9
Computational Theory and Mathematics top 1%
- Computational Drug Discovery Methods 5
Epidemiology top 5%
- Trypanosoma species research and implications 23
Toxicology top 5%
Molecular Biology
- Biochemical and Molecular Research 9
- Protein Tyrosine Phosphatases 5
- Enzyme function and inhibition 4
Immunology
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms 4

Co-authors: Paul G. Wyatt Ian H. Gilbert Denis R. Alexander Ruth Brenk Alan H. Fairlamb Alessandro Schipani Iain T. Collie Emma Shanks
Cited by: Public Health, Environmental and Occupational Health Organic Chemistry Computational Theory and Mathematics
Journals: Journal of Biological Chemistry (2 papers)The Journal of Experimental Medicine (1 paper)PLoS ONE (2 papers)
Partner nations: United Kingdom Norway United States

In The Last Decade

Julie A. Frearson

43 papers receiving 2.1k citations

Hit Papers

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Peers

Countries citing papers authored by Julie A. Frearson

Since Specialization

Citations

This map shows the geographic impact of Julie A. Frearson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Julie A. Frearson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Julie A. Frearson more than expected).

Fields of papers citing papers by Julie A. Frearson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Julie A. Frearson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Julie A. Frearson. The network helps show where Julie A. Frearson may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Julie A. Frearson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Julie A. Frearson Line = papers co-authored together Julie A. Frearson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N -Myristoyltransferase Inhibitors Journal of Medicinal Chemistry ·Justin R. Harrison,Stephen Brand,Victoria Smith,David A. Robinson,Stephen Thompson,Alasdair Smith,Kenneth Davies,N. Yi Mok,Leah S. Torrie,Iain T. Collie,Irene Hallyburton,Suzanne Norval,Frederick R. C. Simeons,Laste Stojanovski,Julie A. Frearson,Ruth Brenk,Paul G. Wyatt,Ian H. Gilbert,Kevin D. Read	2018	46
2	Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors Journal of Medicinal Chemistry ·Tracy Bayliss,David A. Robinson,Victoria Smith,Stephen Brand,Stuart P. McElroy,Leah S. Torrie,Chido Mpamhanga,Suzanne Norval,Laste Stojanovski,Ruth Brenk,Julie A. Frearson,Kevin D. Read,Ian H. Gilbert,Paul G. Wyatt	2017	16
3	Screening a protein kinase inhibitor library against Plasmodium falciparum Malaria Journal ·Irene Hallyburton,Raffaella Grimaldi,Andrew Woodland,Beatriz Baragaña,Torsten Luksch,Daniel Spinks,Daniel James,Didier Leroy,David Waterson,Alan H. Fairlamb,Paul G. Wyatt,Ian H. Gilbert,Julie A. Frearson	2017	16
4	Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay Antimicrobial Agents and Chemotherapy ·Manu De Rycker,Irene Hallyburton,John Thomas,Lorna Campbell,Susan Wyllie,Dhananjay Joshi,Scott Cameron,Ian H. Gilbert,Paul G. Wyatt,Julie A. Frearson,Alan H. Fairlamb,David W. Gray	2013	108
5	From On‐Target to Off‐Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti‐Trypanosoma brucei Drug Discovery Lead Molecules ChemMedChem ·Andrew Woodland,Raffaella Grimaldi,Torsten Luksch,Laura A. T. Cleghorn,Kayode K. Ojo,Wesley C. Van Voorhis,Ruth Brenk,Julie A. Frearson,Ian H. Gilbert,Paul G. Wyatt	2013	22
6	Optimizing the use of CROs by academia and small companies Nature Reviews Drug Discovery ·Rachel Lane,Lauren G. Friedman,Curtis T. Keith,Steven P. Braithwaite,Julie A. Frearson,David A. Lowe,Frank M. Longo,Lorenzo M. Refolo,D. Martin Watterson,Katya Tsaioun,Diana W. Shineman,Howard Fillit	2013	2
7	Assessment of Pseudomonas aeruginosa N5,N10-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target PLoS ONE ·T.C. Eadsforth,Mary Gardiner,Fernando V. Maluf,Stuart P. McElroy,Daniel James,Julie A. Frearson,David W. Gray,William N. Hunter	2012	18
8	Design, Synthesis and Biological Evaluation of Trypanosoma brucei Trypanothione Synthetase Inhibitors ChemMedChem ·Daniel Spinks,Leah S. Torrie,Stephen Thompson,Justin R. Harrison,Julie A. Frearson,Kevin D. Read,Alan H. Fairlamb,Paul G. Wyatt,Ian H. Gilbert	2011	36
9	Optimisation of the Anti‐Trypanosoma brucei Activity of the Opioid Agonist U50488 ChemMedChem ·Victoria Smith,Laura A. T. Cleghorn,Andrew Woodland,Daniel Spinks,Irene Hallyburton,Iain T. Collie,N. Yi Mok,Suzanne Norval,Ruth Brenk,Alan H. Fairlamb,Julie A. Frearson,Kevin D. Read,Ian H. Gilbert,Paul G. Wyatt	2011	6
10	Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening? Current Topics in Medicinal Chemistry ·Ian H. Gilbert,Didier Leroy,Julie A. Frearson	2011	19
11	Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1 ChemMedChem ·Daniel Spinks,Han B. Ong,Chidochangu P. Mpamhanga,Emma Shanks,David A. Robinson,Iain T. Collie,Kevin D. Read,Julie A. Frearson,Paul G. Wyatt,Ruth Brenk,Alan H. Fairlamb,Ian H. Gilbert	2010	32
12	Nuclear DBF-2-related Kinases Are Essential Regulators of Cytokinesis in Bloodstream Stage Trypanosoma brucei Journal of Biological Chemistry ·Jiangtao Ma,Corinna Benz,Raffaella Grimaldi,Christopher Stockdale,Paul G. Wyatt,Julie A. Frearson,Tansy C. Hammarton	2010	29
13	Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis Biochemical Pharmacology ·Deuan C. Jones,Irene Hallyburton,Laste Stojanovski,Kevin D. Read,Julie A. Frearson,Alan H. Fairlamb	2010	56
14	Acetazolamide-based fungal chitinase inhibitors Bioorganic & Medicinal Chemistry ·Alexander W. Schüttelkopf,Ludovic Gros,D.E. Blair,Julie A. Frearson,Daan M. F. van Aalten,Ian H. Gilbert	2010	42
15	HTS and hit finding in academia – from chemical genomics to drug discovery Drug Discovery Today ·Julie A. Frearson,Iain T. Collie	2009	64
16	Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductase Analytical Biochemistry ·Emma Shanks,Han B. Ong,David A. Robinson,Stephen Thompson,Natasha Sienkiewicz,Alan H. Fairlamb,Julie A. Frearson	2009	18
17	Synthesis and Evaluation of 1‐(1‐(Benzo[b]thiophen‐2‐yl)cyclohexyl)piperidine (BTCP) Analogues as Inhibitors of Trypanothione Reductase ChemMedChem ·Stephen Patterson,Deuan C. Jones,Emma Shanks,Julie A. Frearson,Ian H. Gilbert,Paul G. Wyatt,Alan H. Fairlamb	2009	42
18	Target assessment for antiparasitic drug discovery Trends in Parasitology ·Julie A. Frearson,Paul G. Wyatt,Ian H. Gilbert,Alan H. Fairlamb	2007	108
19	The role of phosphotyrosine phosphatases in haematopoietic cell signal transduction BioEssays ·Julie A. Frearson,Denis R. Alexander	1997	59
20	A tyrosine‐phosphorylated 110–120‐kDa protein associates with the C‐terminal SH2 domain of phosphotyrosine phosphatase‐1D in T cell receptor‐stimulated T cells European Journal of Immunology ·Julie A. Frearson,Taolin Yi,Denis R. Alexander	1996	21

About Julie A. Frearson

Julie A. Frearson is a scholar working on Epidemiology, Public Health, Environmental and Occupational Health and Toxicology, having authored 43 papers that have together received 2.2k indexed citations. Recurring topics across this work include Trypanosoma species research and implications (23 papers), Research on Leishmaniasis Studies (15 papers), Biochemical and Molecular Research (9 papers), Synthesis and Biological Evaluation (9 papers), Computational Drug Discovery Methods (5 papers), Protein Tyrosine Phosphatases (5 papers), Enzyme function and inhibition (4 papers) and Neutrophil, Myeloperoxidase and Oxidative Mechanisms (4 papers). The work is most often cited by research in Public Health, Environmental and Occupational Health (723 citations), Organic Chemistry (707 citations) and Computational Theory and Mathematics (373 citations). Julie A. Frearson has collaborated with scholars based in United Kingdom, Norway and United States. Frequent co-authors include Paul G. Wyatt, Ian H. Gilbert, Denis R. Alexander, Ruth Brenk, Alan H. Fairlamb, Alessandro Schipani, Iain T. Collie, Emma Shanks, Deuan C. Jones and Irene Hallyburton. Their work appears in journals such as Journal of Biological Chemistry, The Journal of Experimental Medicine and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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