Kelvin C. Luk

15.4k total citations · 7 hit papers
102 papers, 10.5k citations indexed

About

Kelvin C. Luk is a scholar working on Neurology, Cellular and Molecular Neuroscience and Physiology. According to data from OpenAlex, Kelvin C. Luk has authored 102 papers receiving a total of 10.5k indexed citations (citations by other indexed papers that have themselves been cited), including 87 papers in Neurology, 46 papers in Cellular and Molecular Neuroscience and 35 papers in Physiology. Recurrent topics in Kelvin C. Luk's work include Parkinson's Disease Mechanisms and Treatments (87 papers), Alzheimer's disease research and treatments (34 papers) and Neurological disorders and treatments (34 papers). Kelvin C. Luk is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (87 papers), Alzheimer's disease research and treatments (34 papers) and Neurological disorders and treatments (34 papers). Kelvin C. Luk collaborates with scholars based in United States, Canada and Finland. Kelvin C. Luk's co-authors include Virginia M.‐Y. Lee, John Q. Trojanowski, Patrick O’Brien, Bin Zhang, Victoria Kehm, Laura A. Volpicelli‐Daley, Jenna C. Carroll, Anna Stieber, Abbas F. Sadikot and John Q. Trojanowski and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Kelvin C. Luk

102 papers receiving 10.4k citations

Hit Papers

Pathological α-Synuclein Transmission Initiates Parkinson... 2009 2026 2014 2020 2012 2011 2012 2009 2014 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
    2012 1.9k citations Kelvin C. Luk, Victoria Kehm et al. Science profile →
  2. Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
    2011 1.2k citations Kelvin C. Luk, Anna Stieber et al. profile →
  3. Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
    2012 819 citations Kelvin C. Luk, Victoria Kehm et al. The Journal of Experimental Medicine profile →
  4. Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
    2009 742 citations Kelvin C. Luk, Patrick O’Brien et al. Proceedings of the National Academy of Sciences profile →
  5. Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
    2014 502 citations Kelvin C. Luk, Virginia M.‐Y. Lee et al. profile →
  6. Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies
    2018 439 citations Chao Peng, Ronald J. Gathagan et al. Nature profile →
  7. Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration
    2015 285 citations Kelvin C. Luk, Fredric P. Manfredsson et al. Neurobiology of Disease profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Kelvin C. Luk United States 42 7.6k 4.0k 3.5k 2.8k 2.3k 102 10.5k
Makoto Hashimoto Japan 49 6.1k 0.8× 3.8k 0.9× 3.6k 1.0× 2.5k 0.9× 2.2k 1.0× 126 9.9k
Tammaryn Lashley United Kingdom 48 4.7k 0.6× 1.9k 0.5× 4.4k 1.3× 3.3k 1.2× 2.1k 0.9× 158 9.1k
Michael G. Schlossmacher United States 47 6.9k 0.9× 3.3k 0.8× 5.0k 1.4× 3.7k 1.3× 1.8k 0.8× 81 11.6k
William T. Dauer United States 39 6.2k 0.8× 4.5k 1.1× 1.6k 0.5× 3.5k 1.3× 1.2k 0.5× 91 10.6k
Robert L. Nussbaum United States 39 9.6k 1.3× 5.2k 1.3× 4.2k 1.2× 4.4k 1.6× 2.3k 1.0× 54 14.1k
Pamela J. McLean United States 55 6.4k 0.8× 3.7k 0.9× 4.3k 1.2× 4.3k 1.5× 1.7k 0.7× 112 12.0k
Jada Lewis United States 45 3.3k 0.4× 3.9k 1.0× 7.9k 2.3× 5.0k 1.8× 2.6k 1.1× 95 12.5k
Yaping Chu United States 39 4.1k 0.5× 4.1k 1.0× 1.7k 0.5× 2.8k 1.0× 1.2k 0.5× 70 8.2k
Mel Β. Feany United States 54 5.2k 0.7× 4.8k 1.2× 4.8k 1.4× 5.4k 1.9× 1.8k 0.8× 106 13.4k
Asa Abeliovich United States 30 3.4k 0.4× 3.6k 0.9× 1.6k 0.5× 4.1k 1.5× 1.3k 0.6× 46 8.4k

Countries citing papers authored by Kelvin C. Luk

Since Specialization
Citations

This map shows the geographic impact of Kelvin C. Luk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kelvin C. Luk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kelvin C. Luk more than expected).

Fields of papers citing papers by Kelvin C. Luk

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kelvin C. Luk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kelvin C. Luk. The network helps show where Kelvin C. Luk may publish in the future.

Co-authorship network of co-authors of Kelvin C. Luk

This figure shows the co-authorship network connecting the top 25 collaborators of Kelvin C. Luk. A scholar is included among the top collaborators of Kelvin C. Luk based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kelvin C. Luk. Kelvin C. Luk is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Naseri, Nima, Sarshan R. Pather, Erinc Hallacli, et al.. (2024). Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science Advances. 10(6). eadj4767–eadj4767. 5 indexed citations
3.
Xu, Hong, Qi Qiu, Peng Hu, et al.. (2024). MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons. Acta Neuropathologica. 147(1). 55–55. 3 indexed citations
4.
Kemp, Christopher J., Joseph R. Patterson, Nathan C. Kuhn, et al.. (2024). Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition. Journal of Neuroinflammation. 21(1). 108–108. 5 indexed citations
5.
Balana, Aaron T., Anne‐Laure Mahul‐Mellier, Binh A. Nguyen, et al.. (2024). O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology. Nature Chemical Biology. 20(5). 646–655. 40 indexed citations
6.
Janssen, Bieneke, Guilong Tian, Zsofia Lengyel‐Zhand, et al.. (2023). Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search. Molecular Imaging and Biology. 25(4). 704–719. 8 indexed citations
7.
Kuhn, Nathan C., Joseph R. Patterson, S. Zimmerman, et al.. (2023). Developmental exposure to the Parkinson’s disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice. Toxicological Sciences. 196(1). 99–111. 12 indexed citations
8.
Wie, Jinhong, Zhenjiang Liu, Thomas F. Tropea, et al.. (2021). A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology. Nature. 591(7850). 431–437. 86 indexed citations
9.
Albert, Katrina, Anne Panhelainen, Ave Eesmaa, et al.. (2021). Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo. Molecular Therapy. 29(9). 2821–2840. 27 indexed citations
10.
Bhatia, Tarun N., Patrick G. Needham, Xiaoming Hu, et al.. (2021). Heat Shock Protein 70 as a Sex-Skewed Regulator of α-Synucleinopathy. Neurotherapeutics. 18(4). 2541–2564. 6 indexed citations
11.
Stackhouse, Teresa L., Kateri J. Spinelli, Sydney Weber Boutros, et al.. (2021). Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies. Journal of Biological Chemistry. 296. 100273–100273. 25 indexed citations
12.
Wie, Jinhong, Zhenjiang Liu, Thomas F. Tropea, et al.. (2021). Author Correction: A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology. Nature. 592(7855). E10–E10. 3 indexed citations
13.
Hoban, Deirdre B., Bengt Mattsson, Ludivine S. Breger, et al.. (2020). Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD. Proceedings of the National Academy of Sciences. 117(26). 15209–15220. 47 indexed citations
14.
Manfredsson, Fredric P., Kelvin C. Luk, Matthew J. Benskey, et al.. (2018). Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology. Neurobiology of Disease. 112. 106–118. 139 indexed citations
15.
Peng, Chao, Ronald J. Gathagan, Dustin J. Covell, et al.. (2018). Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies. Nature. 557(7706). 558–563. 439 indexed citations breakdown →
16.
Haenseler, Walther, Heyne Lee, Jane Vowles, et al.. (2017). Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages. Scientific Reports. 7(1). 9003–9003. 93 indexed citations
17.
Rey, Nolwen L., Jennifer A. Steiner, Nazia Maroof, et al.. (2016). Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease. The Journal of Experimental Medicine. 213(9). 1759–1778. 288 indexed citations
18.
Luk, Kelvin C., Victoria Kehm, Jenna C. Carroll, et al.. (2012). Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice. Science. 338(6109). 949–953. 1855 indexed citations breakdown →
19.
Watt, Brenda, Guillaume van Niel, Douglas M. Fowler, et al.. (2009). N-terminal Domains Elicit Formation of Functional Pmel17 Amyloid Fibrils. Journal of Biological Chemistry. 284(51). 35543–35555. 90 indexed citations
20.
Luk, Kelvin C., Timothy E. Kennedy, & Abbas F. Sadikot. (2003). Glutamate Promotes Proliferation of Striatal Neuronal Progenitors by an NMDA Receptor-Mediated Mechanism. Journal of Neuroscience. 23(6). 2239–2250. 104 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Makoto Hashimoto Breakdown of academic impact, for papers by Tammaryn Lashley Breakdown of academic impact, for papers by Michael G. Schlossmacher Breakdown of academic impact, for papers by William T. Dauer Breakdown of academic impact, for papers by Robert L. Nussbaum Breakdown of academic impact, for papers by Pamela J. McLean Breakdown of academic impact, for papers by Jada Lewis Breakdown of academic impact, for papers by Yaping Chu Breakdown of academic impact, for papers by Mel Β. Feany Breakdown of academic impact, for papers by Asa Abeliovich
Rankless by CCL
2026