Lakshmi Changolkar

3.0k total citations · 1 hit paper
29 papers, 2.0k citations indexed

About

Lakshmi Changolkar is a scholar working on Physiology, Molecular Biology and Neurology. According to data from OpenAlex, Lakshmi Changolkar has authored 29 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Physiology, 17 papers in Molecular Biology and 7 papers in Neurology. Recurrent topics in Lakshmi Changolkar's work include Alzheimer's disease research and treatments (20 papers), Prion Diseases and Protein Misfolding (6 papers) and Neuroscience and Neuropharmacology Research (6 papers). Lakshmi Changolkar is often cited by papers focused on Alzheimer's disease research and treatments (20 papers), Prion Diseases and Protein Misfolding (6 papers) and Neuroscience and Neuropharmacology Research (6 papers). Lakshmi Changolkar collaborates with scholars based in United States, China and Switzerland. Lakshmi Changolkar's co-authors include Virginia M.‐Y. Lee, John Q. Trojanowski, Bin Zhang, Sneha Narasimhan, Jennifer D. McBride, John R. Pehrson, Zhuohao He, Jing Guo, Anna Stieber and Ronald J. Gathagan and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

In The Last Decade

Lakshmi Changolkar

29 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation

2017 449 citations Zhuohao He, Jing Guo et al. Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lakshmi Changolkar United States	20	1.3k	932	574	352	294	29	2.0k
Caitlin Commins United States	14	1.1k 0.9×	1.2k 1.3×	393 0.7×	501 1.4×	204 0.7×	21	2.1k
Sneha Narasimhan United States	18	1.3k 1.0×	638 0.7×	729 1.3×	456 1.3×	246 0.8×	23	2.0k
Dag Sehlin Sweden	33	1.6k 1.2×	1.3k 1.4×	619 1.1×	418 1.2×	301 1.0×	85	3.0k
Susanna Schraen‐Maschke France	25	1.2k 0.9×	812 0.9×	387 0.7×	481 1.4×	347 1.2×	66	2.0k
Yukio Matsuba Japan	14	1.6k 1.2×	841 0.9×	556 1.0×	493 1.4×	170 0.6×	25	2.3k
Allyson D. Roe United States	18	1.3k 1.0×	1.1k 1.2×	517 0.9×	435 1.2×	213 0.7×	22	2.2k
Thomas M. Wengenack United States	28	1.4k 1.0×	1.0k 1.1×	304 0.5×	406 1.2×	177 0.6×	40	2.3k
Simon Dujardin United States	19	1.7k 1.3×	1.5k 1.7×	625 1.1×	710 2.0×	352 1.2×	30	3.0k
Hwan‐Ching Tai Taiwan	19	1.1k 0.8×	1.1k 1.1×	365 0.6×	573 1.6×	162 0.6×	41	2.3k
Ayodeji A. Asuni United States	21	1.3k 1.0×	884 0.9×	519 0.9×	566 1.6×	246 0.8×	57	2.0k

Countries citing papers authored by Lakshmi Changolkar

Since Specialization

Citations

This map shows the geographic impact of Lakshmi Changolkar's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lakshmi Changolkar with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lakshmi Changolkar more than expected).

Fields of papers citing papers by Lakshmi Changolkar

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lakshmi Changolkar. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lakshmi Changolkar. The network helps show where Lakshmi Changolkar may publish in the future.

Co-authorship network of co-authors of Lakshmi Changolkar

This figure shows the co-authorship network connecting the top 25 collaborators of Lakshmi Changolkar. A scholar is included among the top collaborators of Lakshmi Changolkar based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lakshmi Changolkar. Lakshmi Changolkar is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Brynildsen, Julia K., Cheryl E. G. Leyns, Lakshmi Changolkar, et al.. (2024). LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression. Translational Neurodegeneration. 13(1). 13–13. 7 indexed citations

Xu, Hong, Qi Qiu, Peng Hu, et al.. (2024). MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons. Acta Neuropathologica. 147(1). 55–55. 3 indexed citations

Farber, Emmanuel, Lakshmi Changolkar, Bin Zhang, et al.. (2024). Targeting Endogenous Tau in Seeded Tauopathy Models Inhibits Tau Spread. Journal of Neuroscience. 44(48). e0877242024–e0877242024. 1 indexed citations

Duan, Pu, Aurelio J. Dregni, Hong Xu, et al.. (2024). Alzheimer’s disease seeded tau forms paired helical filaments yet lacks seeding potential. Journal of Biological Chemistry. 300(9). 107730–107730. 8 indexed citations

McBride, Jennifer D., et al.. (2022). Inhibition of CK2 mitigates Alzheimer’s tau pathology by preventing NR2B synaptic mislocalization. Acta Neuropathologica Communications. 10(1). 30–30. 18 indexed citations

Xu, Hong, Garrett S. Gibbons, Lakshmi Changolkar, et al.. (2021). In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics. Acta Neuropathologica. 141(2). 193–215. 40 indexed citations

Henderson, Michael X., Lakshmi Changolkar, John Q. Trojanowski, & Virginia M.‐Y. Lee. (2021). LRRK2 Kinase Activity Does Not Alter Cell-Autonomous Tau Pathology Development in Primary Neurons. Journal of Parkinson s Disease. 11(3). 1187–1196. 6 indexed citations

Narasimhan, Sneha, Zhuohao He, Lakshmi Changolkar, et al.. (2020). Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo. Journal of Neuropathology & Experimental Neurology. 79(9). 941–949. 10 indexed citations

Gibbons, Garrett S., Soojung Kim, Qihui Wu, et al.. (2020). Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease. Molecular Neurodegeneration. 15(1). 64–64. 30 indexed citations

10.

He, Zhuohao, Jennifer D. McBride, Hong Xu, et al.. (2020). Transmission of tauopathy strains is independent of their isoform composition. Nature Communications. 11(1). 7–7. 135 indexed citations

11.

Prokop, Stefan, Kelly R. Miller, Sneha Narasimhan, et al.. (2019). Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer’s disease patient brain samples. Acta Neuropathologica. 138(4). 613–630. 73 indexed citations

12.

Gibbons, Garrett S., Soojung Kim, John Robinson, et al.. (2019). Detection of Alzheimer’s disease (AD) specific tau pathology with conformation-selective anti-tau monoclonal antibody in co-morbid frontotemporal lobar degeneration-tau (FTLD-tau). Acta Neuropathologica Communications. 7(1). 34–34. 29 indexed citations

13.

Gibbons, Garrett S., Rachel A. Banks, Bumjin Kim, et al.. (2018). Detection of Alzheimer Disease (AD)-Specific Tau Pathology in AD and NonAD Tauopathies by Immunohistochemistry With Novel Conformation-Selective Tau Antibodies. Journal of Neuropathology & Experimental Neurology. 77(3). 216–228. 61 indexed citations

14.

Narasimhan, Sneha, Jing Guo, Lakshmi Changolkar, et al.. (2017). Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain. Journal of Neuroscience. 37(47). 11406–11423. 277 indexed citations

15.

Gibbons, Garrett S., Rachel A. Banks, Bumjin Kim, et al.. (2017). GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils. Journal of Neuroscience. 37(47). 11485–11494. 37 indexed citations

16.

He, Zhuohao, Jing Guo, Jennifer D. McBride, et al.. (2017). Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation. Nature Medicine. 24(1). 29–38. 449 indexed citations breakdown →

17.

Pehrson, John R., Lakshmi Changolkar, Carl Costanzi, & N. Adrian Leu. (2014). Mice without MacroH2A Histone Variants. Molecular and Cellular Biology. 34(24). 4523–4533. 61 indexed citations

18.

Baudino, Lucie, Lakshmi Changolkar, John R. Pehrson, & Shozo Izui. (2010). The Sgp3 locus derived from the 129 strain is responsible for enhanced endogenous retroviral expression in macroH2A1-deficient mice. Journal of Autoimmunity. 35(4). 398–403. 6 indexed citations

19.

Changolkar, Lakshmi, et al.. (2008). macroH2A1-Dependent Silencing of Endogenous Murine Leukemia Viruses. Molecular and Cellular Biology. 28(6). 2059–2065. 33 indexed citations

20.

Changolkar, Lakshmi & John R. Pehrson. (2003). Histone MacroH2A Purification and Nucleosome Reconstitution. Methods in enzymology on CD-ROM/Methods in enzymology. 375. 228–238. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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