Patrick G. Needham

1.5k total citations · 1 hit paper
29 papers, 1.1k citations indexed

About

Patrick G. Needham is a scholar working on Molecular Biology, Cell Biology and Genetics. According to data from OpenAlex, Patrick G. Needham has authored 29 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 9 papers in Cell Biology and 6 papers in Genetics. Recurrent topics in Patrick G. Needham's work include Endoplasmic Reticulum Stress and Disease (8 papers), Heat shock proteins research (7 papers) and Virus-based gene therapy research (3 papers). Patrick G. Needham is often cited by papers focused on Endoplasmic Reticulum Stress and Disease (8 papers), Heat shock proteins research (7 papers) and Virus-based gene therapy research (3 papers). Patrick G. Needham collaborates with scholars based in United States, United Kingdom and Germany. Patrick G. Needham's co-authors include Jeffrey L. Brodsky, Christopher J. Guerriero, Bryan Hurtle, Amanda M. Gleixner, Zachary P. Wills, Lin Guo, Udai Bhan Pandey, Christopher J. Donnelly, James Shorter and Jacob R. Mann and has published in prestigious journals such as Science, Journal of Biological Chemistry and Neuron.

In The Last Decade

Patrick G. Needham

28 papers receiving 1.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

2019 365 citations Jacob R. Mann, Amanda M. Gleixner et al. Neuron profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Patrick G. Needham United States	16	717	312	199	165	107	29	1.1k
Marco Piccinini Italy	18	564 0.8×	124 0.4×	205 1.0×	105 0.6×	118 1.1×	50	1.0k
Tomás Aragón Spain	14	667 0.9×	752 2.4×	56 0.3×	372 2.3×	38 0.4×	23	1.2k
Fumi Kano Japan	25	1.3k 1.8×	732 2.3×	38 0.2×	198 1.2×	33 0.3×	57	1.9k
Douglas J. Lamont United Kingdom	22	829 1.2×	100 0.3×	117 0.6×	176 1.1×	345 3.2×	38	1.4k
J. Thomas Cribbs United States	12	1.4k 1.9×	201 0.6×	89 0.4×	225 1.4×	11 0.1×	12	1.6k
Yahui Yan United Kingdom	14	361 0.5×	249 0.8×	13 0.1×	116 0.7×	39 0.4×	22	714
Brenda Kostelecky United Kingdom	11	1.2k 1.7×	201 0.6×	50 0.3×	335 2.0×	21 0.2×	11	1.4k
Neysan Donnelly Germany	10	892 1.2×	548 1.8×	23 0.1×	205 1.2×	22 0.2×	11	1.3k
Andres Hurtado‐Lorenzo United States	13	677 0.9×	205 0.7×	57 0.3×	249 1.5×	15 0.1×	27	1.2k
Yonghua Liu China	19	688 1.0×	85 0.3×	84 0.4×	62 0.4×	54 0.5×	84	1.1k

Countries citing papers authored by Patrick G. Needham

Since Specialization

Citations

This map shows the geographic impact of Patrick G. Needham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick G. Needham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick G. Needham more than expected).

Fields of papers citing papers by Patrick G. Needham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick G. Needham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick G. Needham. The network helps show where Patrick G. Needham may publish in the future.

Co-authorship network of co-authors of Patrick G. Needham

This figure shows the co-authorship network connecting the top 25 collaborators of Patrick G. Needham. A scholar is included among the top collaborators of Patrick G. Needham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick G. Needham. Patrick G. Needham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Needham, Patrick G., Richard C. Page, & Kevin Yehl. (2024). Phage-layer interferometry: a companion diagnostic for phage therapy and a bacterial testing platform. Scientific Reports. 14(1). 6026–6026. 2 indexed citations

Wright, Bradley W., et al.. (2024). IbpAB small heat shock proteins are not host factors for bacteriophage ϕX174 replication. Virology. 597. 110169–110169. 1 indexed citations

Needham, Patrick G., et al.. (2023). Differential regulation of MAP2 by phosphorylation events in proline‐rich versus C‐terminal domains. The FASEB Journal. 37(10). e23194–e23194. 5 indexed citations

Bhatia, Tarun N., Patrick G. Needham, Xiaoming Hu, et al.. (2021). Heat Shock Protein 70 as a Sex-Skewed Regulator of α-Synucleinopathy. Neurotherapeutics. 18(4). 2541–2564. 6 indexed citations

Cui, Yixian, Muhammad Zahoor, Patrick G. Needham, et al.. (2019). A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science. 365(6448). 53–60. 120 indexed citations

Mann, Jacob R., Amanda M. Gleixner, Jocelyn C. Mauna, et al.. (2019). RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron. 102(2). 321–338.e8. 365 indexed citations breakdown →

Needham, Patrick G., Christopher J. Guerriero, & Jeffrey L. Brodsky. (2019). Chaperoning Endoplasmic Reticulum–Associated Degradation (ERAD) and Protein Conformational Diseases. Cold Spring Harbor Perspectives in Biology. 11(8). a033928–a033928. 97 indexed citations

Kolb, Alexander, Patrick G. Needham, Christopher Szent-Györgyi, et al.. (2018). Select α-arrestins control cell-surface abundance of the mammalian Kir2.1 potassium channel in a yeast model. Journal of Biological Chemistry. 293(28). 11006–11021. 15 indexed citations

Chiang, Annette, Antonio Dominguez‐Meijide, Jennifer L. Goeckeler-Fried, et al.. (2018). Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorganic & Medicinal Chemistry. 27(1). 79–91. 17 indexed citations

10.

Needham, Patrick G., et al.. (2017). Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase. Scientific Reports. 7(1). 1789–1789. 19 indexed citations

11.

Needham, Patrick G., et al.. (2016). Dihydropyrimidinones and -thiones with improved activity against human polyomavirus family members. Bioorganic & Medicinal Chemistry Letters. 26(20). 5087–5091. 22 indexed citations

12.

Needham, Patrick G., Hardik J. Patel, Gabriela Chiosis, Patrick H. Thibodeau, & Jeffrey L. Brodsky. (2015). Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions. Journal of Molecular Biology. 427(18). 2948–2965. 16 indexed citations

13.

Needham, Patrick G., et al.. (2014). Loss of Ypk1, the Yeast Homolog to the Human Serum- and Glucocorticoid-induced Protein Kinase, Accelerates Phospholipase B1-mediated Phosphatidylcholine Deacylation. Journal of Biological Chemistry. 289(45). 31591–31604. 13 indexed citations

14.

Kolb, Alexander, et al.. (2013). ESCRT regulates surface expression of the Kir2.1 potassium channel. Molecular Biology of the Cell. 25(2). 276–289. 29 indexed citations

15.

Needham, Patrick G., et al.. (2011). The Thiazide-sensitive NaCl Cotransporter Is Targeted for Chaperone-dependent Endoplasmic Reticulum-associated Degradation. Journal of Biological Chemistry. 286(51). 43611–43621. 41 indexed citations

16.

Chiang, Annette, Patrick G. Needham, Linda L. Stephens, et al.. (2010). Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock. Cell Stress and Chaperones. 16(4). 389–401. 43 indexed citations

17.

Needham, Patrick G. & Daniel C. Masison. (2008). Prion-impairing mutations in Hsp70 chaperone Ssa1: Effects on ATPase and chaperone activities. Archives of Biochemistry and Biophysics. 478(2). 167–174. 23 indexed citations

18.

Needham, Patrick G., et al.. (2006). Adeno-associated virus interactions with B23/Nucleophosmin: Identification of sub-nucleolar virion regions. Virology. 357(1). 102–113. 48 indexed citations

19.

Needham, Patrick G. & Robert Trumbly. (2006). In vitro characterization of the Mig1 repressor from Saccharomyces cerevisiae reveals evidence for monomeric and higher molecular weight forms. Yeast. 23(16). 1151–1166. 5 indexed citations

20.

Viegas, O. A. C., et al.. (1982). Dietary protein energy supplementation of pregnant Asian mothers at Sorrento, Birmingham. II: Selective during third trimester only.. BMJ. 285(6342). 592–595. 73 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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