John R. Engen

17.1k total citations · 4 hit papers
194 papers, 11.3k citations indexed

About

John R. Engen is a scholar working on Molecular Biology, Spectroscopy and Materials Chemistry. According to data from OpenAlex, John R. Engen has authored 194 papers receiving a total of 11.3k indexed citations (citations by other indexed papers that have themselves been cited), including 133 papers in Molecular Biology, 59 papers in Spectroscopy and 23 papers in Materials Chemistry. Recurrent topics in John R. Engen's work include Mass Spectrometry Techniques and Applications (57 papers), Protein Structure and Dynamics (35 papers) and Analytical Chemistry and Chromatography (33 papers). John R. Engen is often cited by papers focused on Mass Spectrometry Techniques and Applications (57 papers), Protein Structure and Dynamics (35 papers) and Analytical Chemistry and Chromatography (33 papers). John R. Engen collaborates with scholars based in United States, Germany and United Kingdom. John R. Engen's co-authors include Thomas E. Wales, Steven A. Berkowitz, Roxana E. Iacob, Damian J. Houde, Thomas E. Smithgall, David D. Weis, Graham B. Jones, Jeffrey R. Mazzeo, Nathanael S. Gray and Kasper D. Rand and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

John R. Engen

193 papers receiving 11.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

2009 785 citations Wenjun Zhou, Dalia Ercan et al. Nature profile →
Hydrogen exchange mass spectrometry for the analysis of protein dynamics

2005 682 citations Thomas E. Wales, John R. Engen profile →
Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems

2021 183 citations John R. Engen, Miklós Guttman et al. profile →
Structural mechanism of a drug-binding process involving a large conformational change of the protein target

2023 59 citations Roxana E. Iacob, John R. Engen et al. profile →

Peers

Countries citing papers authored by John R. Engen

Since Specialization

Citations

This map shows the geographic impact of John R. Engen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John R. Engen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John R. Engen more than expected).

Fields of papers citing papers by John R. Engen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John R. Engen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John R. Engen. The network helps show where John R. Engen may publish in the future.

Co-authorship network of co-authors of John R. Engen

This figure shows the co-authorship network connecting the top 25 collaborators of John R. Engen. A scholar is included among the top collaborators of John R. Engen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John R. Engen. John R. Engen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Rigorous Analysis of Multimodal HDX-MS Spectra 2025 ·Journal of the American Society for Mass Spectrometry ·Lisa M. Tuttle, (unknown), Florian Georgescauld, Thomas E. Wales, David D. Weis, John R. Engen, Abhinav Nath, Rachel E. Klevit, Miklós Guttman	4
2	Resolving chaperone-assisted protein folding on the ribosome at the peptide level 2024 ·Nature Structural & Molecular Biology ·Thomas E. Wales, Aleksandra Pajak, (unknown), (unknown), Steven Howell, Svend Kjær, F. Ulrich Hartl, John R. Engen, David Balchin	9
3	Dynamic conformational equilibria in the active states of KRAS and NRAS 2024 ·RSC Chemical Biology ·(unknown), Chrystèle Henry, Callum J. Dickson, Florian Georgescauld, Thomas E. Wales, Dirk Erdmann, Simona Cotesta, Sauveur-Michel Maira, Richard Sedrani, Saskia M. Brachmann, Nils Ostermann, John R. Engen, Lewis E. Kay, Kim S. Beyer, Rainer Wilcken, Wolfgang Jahnke	7
4	An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck 2024 ·Journal of Biological Chemistry ·(unknown), (unknown), (unknown), Thomas E. Wales, Shiying Cui, (unknown), John R. Engen, Carlos J. Camacho, Rieko Ishima, Thomas E. Smithgall	0
5	The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction 2024 ·Proceedings of the National Academy of Sciences ·Ju Rang Woo, (unknown), Thomas E. Wales, John R. Engen, Jongsoon Lee, Hyonchol Jang, SangYoun Park	13
6	Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states 2023 ·eLife ·David Yin-wei Lin, (unknown), Puneet Juneja, Thomas E. Wales, John R. Engen, Amy H. Andreotti	4
7	Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change 2022 ·Journal of Biological Chemistry ·Yang Su, Roxana E. Iacob, Jing Li, John R. Engen, Timothy A. Springer	17
8	Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase 2021 ·Molecular Cell ·Zhejian Ji, Hao Li, Daniele Peterle, João A. Paulo, Scott B. Ficarro, Thomas E. Wales, Jarrod A. Marto, Steven P. Gygi, John R. Engen, Tom A. Rapoport	55
9	Identification of a Structural Determinant for Selective Targeting of HDMX 2020 ·Structure ·Yael Ben‐Nun, Hyuk‐Soo Seo, (unknown), (unknown), Thomas E. Wales, (unknown), (unknown), John R. Engen, Sirano Dhe‐Paganon, Loren D. Walensky	6
10	Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding 2019 ·Science ·Edward C. Twomey, Zhejian Ji, Thomas E. Wales, (unknown), Scott B. Ficarro, Jarrod A. Marto, John R. Engen, Tom A. Rapoport	221
11	Remodeling of the Binding Site of Nucleoside Diphosphate Kinase Revealed by X-ray Structure and H/D Exchange 2019 ·Biochemistry ·Alain Dautant, Julien Henri, Thomas E. Wales, Philippe Meyer, John R. Engen, Florian Georgescauld	2
12	Tolloid cleavage activates latent GDF8 by priming the pro‐complex for dissociation 2018 ·The EMBO Journal ·Viet Q. Le, Roxana E. Iacob, Yuan Tian, (unknown), Justin Jackson, Yang Su, Bo Zhao, John R. Engen, Michelle Pirruccello, Timothy A. Springer	27
13	Mechanism of Enzyme Repair by the AAA+ Chaperone Rubisco Activase 2017 ·Molecular Cell ·Javaid Y. Bhat, Goran Miličić, (unknown), Andreas Bracher, (unknown), (unknown), Oliver Mueller‐Cajar, John R. Engen, F. Ulrich Hartl, Petra Wendler, Manajit Hayer‐Hartl	52
14	Steric gate residues of Y-family DNA polymerases DinB and pol kappa are crucial for dNTP-induced conformational change 2015 ·DNA repair ·(unknown), John R. Engen, Penny J. Beuning	16
15	Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes 2012 ·Structure ·Sung Hee Choi, Thomas E. Wales, Yunsun Nam, Daniel J. O’Donovan, Piotr Sliz, John R. Engen, Stephen C. Blacklow	46
16	Validation of an Ion Mobility Hydrogen/Deuterium Exchange Mass Spectrometry System. 2011 ·Journal of Biomolecular Techniques JBT ·Thomas E. Wales, Martha Stapels, Michael J. Eggertson, John R. Engen, Keith E. Fadgen	1
17	Hydrogen exchange mass spectrometry: what is it and what can it tell us? 2010 ·Analytical and Bioanalytical Chemistry ·Sean R. Marcsisin, John R. Engen	150
18	Novel mutant-selective EGFR kinase inhibitors against EGFR T790M breakdown → 2009 ·Nature ·Wenjun Zhou, Dalia Ercan, Liang Chen, Cai‐Hong Yun, Danan Li, Marzia Capelletti, Alexis B. Cortot, Lucian R. Chirieac, Roxana E. Iacob, Robert F. Padera, John R. Engen, Kwok‐Kin Wong, Michael J. Eck, Nathanael S. Gray, Pasi A. Jänne	785
19	Aspartic proteinases in Antarctic fish 2009 ·Marine Genomics ·Viviana De Luca, (unknown), (unknown), Giuliana Catara, Vincenzo Carginale, (unknown), Antonio Capasso, Elio Parisi, Sébastien Brier, John R. Engen, Clemente Capasso	16
20	Purification and characterization of pepsins A1 and A2 from the Antarctic rock cod Trematomus bernacchii 2007 ·FEBS Journal ·Sébastien Brier, (unknown), Vincenzo Carginale, Antonio Capasso, Yan Wu, Robert M. Taylor, Nicholas B. Borotto, Clemente Capasso, John R. Engen	39

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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