Roxana E. Iacob

5.3k total citations · 2 hit papers
34 papers, 2.4k citations indexed

About

Roxana E. Iacob is a scholar working on Molecular Biology, Radiology, Nuclear Medicine and Imaging and Spectroscopy. According to data from OpenAlex, Roxana E. Iacob has authored 34 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 23 papers in Molecular Biology, 10 papers in Radiology, Nuclear Medicine and Imaging and 8 papers in Spectroscopy. Recurrent topics in Roxana E. Iacob's work include Monoclonal and Polyclonal Antibodies Research (10 papers), Mass Spectrometry Techniques and Applications (8 papers) and Chronic Myeloid Leukemia Treatments (5 papers). Roxana E. Iacob is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (10 papers), Mass Spectrometry Techniques and Applications (8 papers) and Chronic Myeloid Leukemia Treatments (5 papers). Roxana E. Iacob collaborates with scholars based in United States, Germany and Romania. Roxana E. Iacob's co-authors include John R. Engen, Nathanael S. Gray, Kwok‐Kin Wong, Lucian R. Chirieac, Dalia Ercan, Robert F. Padera, Cai‐Hong Yun, Pasi A. Jänne, Michael J. Eck and Liang Chen and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Roxana E. Iacob

34 papers receiving 2.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

2009 785 citations Wenjun Zhou, Dalia Ercan et al. Nature profile →
Structural mechanism of a drug-binding process involving a large conformational change of the protein target

2023 59 citations Pelin Ayaz, Agatha Lyczek et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Roxana E. Iacob United States	24	1.6k	679	581	407	293	34	2.4k
Kimberly A. Lee United States	15	1.8k 1.1×	403 0.6×	183 0.3×	669 1.6×	120 0.4×	19	2.4k
Ricardo M. Attar United States	30	1.7k 1.1×	877 1.3×	827 1.4×	58 0.1×	385 1.3×	72	3.2k
Elżbieta Izbicka United States	31	2.1k 1.3×	748 1.1×	421 0.7×	120 0.3×	83 0.3×	96	3.1k
Wilson B. Knight United States	23	1.0k 0.7×	770 1.1×	253 0.4×	76 0.2×	290 1.0×	46	1.9k
Rafael de Llorens Spain	32	1.7k 1.1×	690 1.0×	233 0.4×	257 0.6×	316 1.1×	61	2.4k
Pamela L. Paris United States	30	2.0k 1.3×	853 1.3×	1.6k 2.8×	89 0.2×	150 0.5×	68	3.8k
Simon Bergqvist United States	25	1.5k 0.9×	599 0.9×	305 0.5×	63 0.2×	123 0.4×	35	2.3k
Katherine R. Kozak United States	24	965 0.6×	760 1.1×	126 0.2×	258 0.6×	674 2.3×	39	2.0k
Dennis R. Benjamin United States	18	1.0k 0.6×	1.2k 1.8×	87 0.1×	232 0.6×	1.0k 3.5×	41	2.3k
William T. Windsor United States	23	1.5k 0.9×	876 1.3×	212 0.4×	69 0.2×	226 0.8×	42	2.5k

Countries citing papers authored by Roxana E. Iacob

Since Specialization

Citations

This map shows the geographic impact of Roxana E. Iacob's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roxana E. Iacob with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roxana E. Iacob more than expected).

Fields of papers citing papers by Roxana E. Iacob

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roxana E. Iacob. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roxana E. Iacob. The network helps show where Roxana E. Iacob may publish in the future.

Co-authorship network of co-authors of Roxana E. Iacob

This figure shows the co-authorship network connecting the top 25 collaborators of Roxana E. Iacob. A scholar is included among the top collaborators of Roxana E. Iacob based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Roxana E. Iacob. Roxana E. Iacob is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sun, Yan, Damian J. Houde, Roxana E. Iacob, et al.. (2025). Hydrogen/Deuterium Exchange and Protein Oxidative Footprinting with Mass Spectrometry Collectively Discriminate the Binding of Small-Molecule Therapeutics to Bcl-2. Analytical Chemistry. 97(8). 4329–4340. 2 indexed citations

Ayaz, Pelin, Agatha Lyczek, Roxana E. Iacob, et al.. (2023). Structural mechanism of a drug-binding process involving a large conformational change of the protein target. Nature Communications. 14(1). 1885–1885. 59 indexed citations breakdown →

Su, Yang, Roxana E. Iacob, Jing Li, John R. Engen, & Timothy A. Springer. (2022). Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change. Journal of Biological Chemistry. 298(9). 102323–102323. 17 indexed citations

Le, Viet Q., Roxana E. Iacob, Bo Zhao, et al.. (2022). Protection of the Prodomain α1-Helix Correlates with Latency in the Transforming Growth Factor-β Family. Journal of Molecular Biology. 434(5). 167439–167439. 6 indexed citations

Bonazza, Klaus, Roxana E. Iacob, Nathan E. Hudson, et al.. (2022). Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N- and C-linker. eLife. 11. 8 indexed citations

Su, Yang, et al.. (2019). General structural features that regulate integrin affinity revealed by atypical αVβ8. Nature Communications. 10(1). 5481–5481. 27 indexed citations

Le, Viet Q., Roxana E. Iacob, Yuan Tian, et al.. (2018). Tolloid cleavage activates latent GDF8 by priming the pro‐complex for dissociation. The EMBO Journal. 37(3). 384–397. 27 indexed citations

Iacob, Roxana E., et al.. (2018). Hydrogen-Deuterium Exchange Mass Spectrometry to Study Protein Complexes. Methods in molecular biology. 1764. 153–171. 29 indexed citations

Lamberto, Ilaria, Xiaoxi Liu, Hyuk‐Soo Seo, et al.. (2017). Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Cell chemical biology. 24(12). 1490–1500.e11. 137 indexed citations

10.

Dong, Xianchi, Bo Zhao, Roxana E. Iacob, et al.. (2017). Force interacts with macromolecular structure in activation of TGF-β. Nature. 542(7639). 55–59. 208 indexed citations

11.

Iacob, Roxana E., Stanley R. Krystek, Richard Y.‐C. Huang, et al.. (2015). Hydrogen/deuterium exchange mass spectrometry applied to IL-23 interaction characteristics: potential impact for therapeutics. Expert Review of Proteomics. 12(2). 159–169. 25 indexed citations

12.

Moroco, Jamie A., Jodi K. Craigo, Roxana E. Iacob, et al.. (2014). Differential Sensitivity of Src-Family Kinases to Activation by SH3 Domain Displacement. PLoS ONE. 9(8). e105629–e105629. 30 indexed citations

13.

Panjarian, Shoghag, Roxana E. Iacob, Shugui Chen, et al.. (2013). Enhanced SH3/Linker Interaction Overcomes Abl Kinase Activation by Gatekeeper and Myristic Acid Binding Pocket Mutations and Increases Sensitivity to Small Molecule Inhibitors*. Journal of Biological Chemistry. 288(9). 6116–6129. 30 indexed citations

14.

Iacob, Roxana E., George M. Bou-Assaf, Lee Makowski, et al.. (2013). Investigating Monoclonal Antibody Aggregation Using a Combination of H/DX-MS and Other Biophysical Measurements. Journal of Pharmaceutical Sciences. 102(12). 4315–4329. 73 indexed citations

15.

Panjarian, Shoghag, Roxana E. Iacob, Shugui Chen, John R. Engen, & Thomas E. Smithgall. (2013). Structure and Dynamic Regulation of Abl Kinases*. Journal of Biological Chemistry. 288(8). 5443–5450. 97 indexed citations

16.

Iacob, Roxana E., Jianming Zhang, Nathanael S. Gray, & John R. Engen. (2011). Allosteric Interactions between the Myristate- and ATP-Site of the Abl Kinase. PLoS ONE. 6(1). e15929–e15929. 56 indexed citations

17.

Zhou, Wenjun, Dalia Ercan, Liang Chen, et al.. (2009). Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature. 462(7276). 1070–1074. 785 indexed citations breakdown →

18.

Iacob, Roxana E., et al.. (2009). Functional and Structural Characterization of Factor Xa Dimer in Solution. Biophysical Journal. 96(3). 974–986. 10 indexed citations

19.

Iacob, Roxana E., Zhen–Yong Keck, Oakley C. Olson, Steven K. H. Foung, & Kenneth B. Tomer. (2008). Structural elucidation of critical residues involved in binding of human monoclonal antibodies to hepatitis C virus E2 envelope glycoprotein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1784(3). 530–542. 15 indexed citations

20.

Iacob, Roxana E., James Peter Murphy, & John R. Engen. (2008). Ion mobility adds an additional dimension to mass spectrometric analysis of solution‐phase hydrogen/deuterium exchange. Rapid Communications in Mass Spectrometry. 22(18). 2898–2904. 58 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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