Sirano Dhe‐Paganon

14.0k total citations · 3 hit papers
111 papers, 8.8k citations indexed

About

Sirano Dhe‐Paganon is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Sirano Dhe‐Paganon has authored 111 papers receiving a total of 8.8k indexed citations (citations by other indexed papers that have themselves been cited), including 98 papers in Molecular Biology, 29 papers in Oncology and 13 papers in Cell Biology. Recurrent topics in Sirano Dhe‐Paganon's work include Ubiquitin and proteasome pathways (31 papers), Protein Degradation and Inhibitors (22 papers) and Peptidase Inhibition and Analysis (16 papers). Sirano Dhe‐Paganon is often cited by papers focused on Ubiquitin and proteasome pathways (31 papers), Protein Degradation and Inhibitors (22 papers) and Peptidase Inhibition and Analysis (16 papers). Sirano Dhe‐Paganon collaborates with scholars based in United States, Canada and Austria. Sirano Dhe‐Paganon's co-authors include Steven E. Shoelson, James E. Bradner, Joshiawa Paulk, Michael J. Eck, Dennis L. Buckley, John R. Walker, Justin M. Roberts, Amanda Souza, Georg E. Winter and Scott Pluskey and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Sirano Dhe‐Paganon

108 papers receiving 8.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Phthalimide conjugation as a strategy for in vivo target protein degradation

2015 1.3k citations Georg E. Winter, Dennis L. Buckley et al. Science profile →
Crystal Structure of the Tyrosine Phosphatase SHP-2

1998 786 citations Sirano Dhe‐Paganon, Steven E. Shoelson et al. Cell profile →
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease

2023 95 citations Raaj S. Mehta, Jared R. Mayers et al. Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sirano Dhe‐Paganon United States	47	7.4k	1.9k	1.1k	852	762	111	8.8k
Mikihiko Naito Japan	54	6.6k 0.9×	3.5k 1.8×	604 0.6×	648 0.8×	1.3k 1.7×	224	9.7k
Brian Leber Canada	49	6.3k 0.8×	1.3k 0.7×	1.2k 1.1×	576 0.7×	1.6k 2.1×	196	9.5k
Marketa Zvelebil United Kingdom	49	5.8k 0.8×	1.6k 0.8×	1.1k 1.0×	1.2k 1.4×	252 0.3×	102	8.2k
Aviv Gazit Israel	45	5.3k 0.7×	3.3k 1.7×	1.3k 1.2×	615 0.7×	1.0k 1.4×	99	9.7k
Marco Falasca Australia	51	5.4k 0.7×	2.1k 1.1×	862 0.8×	1.6k 1.8×	344 0.5×	183	8.7k
Matthieu Schapira Canada	46	8.2k 1.1×	1.1k 0.6×	559 0.5×	2.0k 2.3×	416 0.5×	114	10.4k
Edward Y. Skolnik United States	52	7.5k 1.0×	1.6k 0.8×	1.6k 1.5×	2.1k 2.5×	260 0.3×	84	11.2k
Roya Khosravi‐Far United States	44	6.8k 0.9×	1.9k 1.0×	975 0.9×	2.1k 2.5×	344 0.5×	80	8.7k
Namrata D. Udeshi United States	37	7.7k 1.0×	1.1k 0.6×	888 0.8×	3.0k 3.5×	763 1.0×	81	10.0k
Sarah J. Parsons United States	53	6.3k 0.8×	3.0k 1.6×	800 0.7×	1.7k 2.0×	387 0.5×	117	9.7k

Countries citing papers authored by Sirano Dhe‐Paganon

Since Specialization

Citations

This map shows the geographic impact of Sirano Dhe‐Paganon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sirano Dhe‐Paganon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sirano Dhe‐Paganon more than expected).

Fields of papers citing papers by Sirano Dhe‐Paganon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sirano Dhe‐Paganon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sirano Dhe‐Paganon. The network helps show where Sirano Dhe‐Paganon may publish in the future.

Co-authorship network of co-authors of Sirano Dhe‐Paganon

This figure shows the co-authorship network connecting the top 25 collaborators of Sirano Dhe‐Paganon. A scholar is included among the top collaborators of Sirano Dhe‐Paganon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sirano Dhe‐Paganon. Sirano Dhe‐Paganon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Gracia-Hernandez, Maria, Abootaleb Sedighi, Mulu Geletu, et al.. (2025). Improved Pharmacokinetic Profiles of HDAC6 Inhibitors via Cap Group Modifications. Journal of Medicinal Chemistry. 68(17). 18216–18229.

Adhikary, Utsarga, Kyle J. Korshavn, Hyuk‐Soo Seo, et al.. (2025). Structural insights into chemoresistance mutants of BCL-2 and their targeting by stapled BAD BH3 helices. Nature Communications. 16(1). 8623–8623.

Hwang, Grace H., Maria F. Pazyra‐Murphy, Hyuk‐Soo Seo, et al.. (2024). A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma. Cancer Research. 84(6). 872–886. 2 indexed citations

Mehta, Raaj S., Jared R. Mayers, Yancong Zhang, et al.. (2023). Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nature Medicine. 29(3). 700–709. 95 indexed citations breakdown →

Sewastianik, Tomasz, Hyuk‐Soo Seo, David Remillard, et al.. (2022). A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer. Science Advances. 8(17). eabm3108–eabm3108. 26 indexed citations

Johnson, Christian W., Hyuk‐Soo Seo, Elizabeth M. Terrell, et al.. (2022). Regulation of GTPase function by autophosphorylation. Molecular Cell. 82(5). 950–968.e14. 11 indexed citations

Fukuda, Yusuke, Maria F. Pazyra‐Murphy, Elizabeth S. Silagi, et al.. (2020). Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival. The Journal of Cell Biology. 220(1). 46 indexed citations

Gibson, William J., Meredith S. Brown, Jack A. Kosmicki, et al.. (2020). Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities. Nature Communications. 11(1). 2517–2517. 67 indexed citations

Manz, Theresa, Fleur M. Ferguson, Tinghu Zhang, et al.. (2020). Discovery and Structure–Activity Relationship Study of ( Z )-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Journal of Medicinal Chemistry. 63(9). 4880–4895. 18 indexed citations

10.

Manz, Theresa, Adam Yasgar, Matthew D. Hall, et al.. (2019). Structure–Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. ACS Medicinal Chemistry Letters. 11(3). 346–352. 13 indexed citations

11.

Valencia, Alfredo M., Clayton K. Collings, Hai T. Dao, et al.. (2019). Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. 179(6). 1342–1356.e23. 76 indexed citations

12.

Erb, Michael A., Thomas G. Scott, Bin E. Li, et al.. (2017). Transcription control by the ENL YEATS domain in acute leukaemia. RePEc: Research Papers in Economics. 1 indexed citations

13.

Winter, Georg E., Dennis L. Buckley, Joshiawa Paulk, et al.. (2015). Phthalimide conjugation as a strategy for in vivo target protein degradation. Science. 348(6241). 1376–1381. 1253 indexed citations breakdown →

14.

Honson, Nicolette S., Tara L. Davis, Sirano Dhe‐Paganon, et al.. (2014). Development of Fluorescent Substrates and Assays for the Key Autophagy-Related Cysteine Protease Enzyme, ATG4B. Assay and Drug Development Technologies. 12(3). 176–189. 30 indexed citations

15.

Colwill, Karen, et al.. (2013). MERTK Interactions with SH2-Domain Proteins in the Retinal Pigment Epithelium. PLoS ONE. 8(2). e53964–e53964. 21 indexed citations

16.

Syeda, Farisa, Rebecca L. Fagan, G.V. Avvakumov, et al.. (2011). The Replication Focus Targeting Sequence (RFTS) Domain Is a DNA-competitive Inhibitor of Dnmt1. Journal of Biological Chemistry. 286(17). 15344–15351. 98 indexed citations

17.

Himanen, Juha P., Peter W. Janes, John R. Walker, et al.. (2010). Architecture of Eph receptor clusters. Proceedings of the National Academy of Sciences. 107(24). 10860–10865. 208 indexed citations

18.

Kang, Gil Bu, Dong Yeon Shin, Ji-Hye Yun, et al.. (2010). Structural Basis of E2–25K/UBB+1 Interaction Leading to Proteasome Inhibition and Neurotoxicity. Journal of Biological Chemistry. 285(46). 36070–36080. 45 indexed citations

19.

Avvakumov, G.V., John R. Walker, Sheng Xue, et al.. (2006). Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). Journal of Biological Chemistry. 281(49). 38061–38070. 127 indexed citations

20.

Nishi, Masahiro, Eric D. Werner, Byung‐Chul Oh, et al.. (2005). Kinase Activation through Dimerization by Human SH2-B. Molecular and Cellular Biology. 25(7). 2607–2621. 49 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact