Thomas E. Wales

6.8k total citations · 1 hit paper
89 papers, 3.8k citations indexed

About

Thomas E. Wales is a scholar working on Molecular Biology, Spectroscopy and Oncology. According to data from OpenAlex, Thomas E. Wales has authored 89 papers receiving a total of 3.8k indexed citations (citations by other indexed papers that have themselves been cited), including 63 papers in Molecular Biology, 23 papers in Spectroscopy and 14 papers in Oncology. Recurrent topics in Thomas E. Wales's work include Mass Spectrometry Techniques and Applications (22 papers), Protein Structure and Dynamics (19 papers) and Analytical Chemistry and Chromatography (14 papers). Thomas E. Wales is often cited by papers focused on Mass Spectrometry Techniques and Applications (22 papers), Protein Structure and Dynamics (19 papers) and Analytical Chemistry and Chromatography (14 papers). Thomas E. Wales collaborates with scholars based in United States, United Kingdom and France. Thomas E. Wales's co-authors include John R. Engen, Keith E. Fadgen, Geoff C. Gerhardt, Loren D. Walensky, Thomas E. Smithgall, David D. Weis, Jamie A. Moroco, Tom A. Rapoport, Zhejian Ji and Jarrod A. Marto and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Thomas E. Wales

87 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hydrogen exchange mass spectrometry for the analysis of protein dynamics

2005 682 citations Thomas E. Wales, John R. Engen profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thomas E. Wales United States	31	2.6k	951	457	358	316	89	3.8k
Rasmus H. Fogh United Kingdom	16	2.8k 1.1×	450 0.5×	335 0.7×	606 1.7×	175 0.6×	27	3.6k
John H. Bushweller United States	44	4.9k 1.9×	503 0.5×	657 1.4×	453 1.3×	545 1.7×	113	6.1k
Perttu Permi Finland	35	2.0k 0.8×	564 0.6×	585 1.3×	488 1.4×	137 0.4×	147	3.6k
Vincent Madison United States	40	3.2k 1.2×	667 0.7×	208 0.5×	340 0.9×	489 1.5×	97	4.7k
Daiwen Yang Singapore	38	3.3k 1.3×	1.3k 1.3×	358 0.8×	953 2.7×	238 0.8×	151	4.4k
Simone Lemeer Netherlands	34	3.5k 1.3×	2.1k 2.2×	465 1.0×	198 0.6×	429 1.4×	55	4.7k
Steven M. Pascal United States	19	2.6k 1.0×	486 0.5×	331 0.7×	569 1.6×	207 0.7×	44	3.2k
N. Rama Krishna United States	31	2.4k 0.9×	563 0.6×	418 0.9×	340 0.9×	204 0.6×	127	3.9k
Michael C. Fitzgerald United States	35	2.5k 1.0×	1.6k 1.7×	332 0.7×	493 1.4×	241 0.8×	123	3.9k
John Ionides United Kingdom	6	2.3k 0.9×	292 0.3×	281 0.6×	466 1.3×	155 0.5×	9	2.9k

Countries citing papers authored by Thomas E. Wales

Since Specialization

Citations

This map shows the geographic impact of Thomas E. Wales's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas E. Wales with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas E. Wales more than expected).

Fields of papers citing papers by Thomas E. Wales

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas E. Wales. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas E. Wales. The network helps show where Thomas E. Wales may publish in the future.

Co-authorship network of co-authors of Thomas E. Wales

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas E. Wales. A scholar is included among the top collaborators of Thomas E. Wales based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas E. Wales. Thomas E. Wales is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tuttle, Lisa M., Florian Georgescauld, Thomas E. Wales, et al.. (2025). Rigorous Analysis of Multimodal HDX-MS Spectra. Journal of the American Society for Mass Spectrometry. 36(2). 416–423. 4 indexed citations

Adhikary, Utsarga, Kyle J. Korshavn, Hyuk‐Soo Seo, et al.. (2025). Structural insights into chemoresistance mutants of BCL-2 and their targeting by stapled BAD BH3 helices. Nature Communications. 16(1). 8623–8623.

Joseph, R, Thomas E. Wales, Sandrine Jayne, et al.. (2024). Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia. eLife. 13. 5 indexed citations

Wales, Thomas E., Shiying Cui, John R. Engen, et al.. (2024). An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck. Journal of Biological Chemistry. 301(1). 108088–108088.

Wales, Thomas E., Aleksandra Pajak, Steven Howell, et al.. (2024). Resolving chaperone-assisted protein folding on the ribosome at the peptide level. Nature Structural & Molecular Biology. 31(12). 1888–1897. 9 indexed citations

Henry, Chrystèle, Callum J. Dickson, Florian Georgescauld, et al.. (2024). Dynamic conformational equilibria in the active states of KRAS and NRAS. RSC Chemical Biology. 6(1). 106–118. 7 indexed citations

Valle‐Argos, Beatriz, Thomas E. Wales, R Joseph, et al.. (2024). Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story. Journal of Medicinal Chemistry. 67(16). 13572–13593. 2 indexed citations

Woo, Ju Rang, Thomas E. Wales, John R. Engen, et al.. (2024). The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction. Proceedings of the National Academy of Sciences. 121(17). 13 indexed citations

Klimtchuk, Elena S., Tatiana Prokaeva, Brian Spencer, et al.. (2024). Conformational Differences in the Light Chain Constant Domain of Immunoglobulin G and Free Light Chain May Influence Proteolysis in AL Amyloidosis. Journal of Molecular Biology. 436(23). 168837–168837. 3 indexed citations

10.

Lin, David Yin-wei, et al.. (2023). Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. eLife. 12. 4 indexed citations

11.

Ji, Zhejian, Hao Li, Daniele Peterle, et al.. (2021). Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase. Molecular Cell. 82(3). 570–584.e8. 55 indexed citations

12.

Ben‐Nun, Yael, Hyuk‐Soo Seo, Thomas E. Wales, et al.. (2020). Identification of a Structural Determinant for Selective Targeting of HDMX. Structure. 28(7). 847–857.e5. 6 indexed citations

13.

Twomey, Edward C., Zhejian Ji, Thomas E. Wales, et al.. (2019). Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science. 365(6452). 221 indexed citations

14.

Dautant, Alain, Julien Henri, Thomas E. Wales, et al.. (2019). Remodeling of the Binding Site of Nucleoside Diphosphate Kinase Revealed by X-ray Structure and H/D Exchange. Biochemistry. 58(10). 1440–1449. 2 indexed citations

15.

Tsukamoto, Kosuke, Thomas E. Wales, Kathleen Daniels, et al.. (2013). Noncanonical Role of the PDZ4 Domain of the Adaptor Protein PDZK1 in the Regulation of the Hepatic High Density Lipoprotein Receptor Scavenger Receptor Class B, Type I (SR-BI). Journal of Biological Chemistry. 288(27). 19845–19860. 13 indexed citations

16.

Choi, Sung Hee, Thomas E. Wales, Yunsun Nam, et al.. (2012). Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes. Structure. 20(2). 340–349. 46 indexed citations

17.

Wales, Thomas E., Martha Stapels, Michael J. Eggertson, John R. Engen, & Keith E. Fadgen. (2011). Validation of an Ion Mobility Hydrogen/Deuterium Exchange Mass Spectrometry System.. Journal of Biomolecular Techniques JBT. 22. 1 indexed citations

18.

Engen, John R., Thomas E. Wales, James Michael Hochrein, et al.. (2008). Structure and dynamic regulation of Src-family kinases. Cellular and Molecular Life Sciences. 65(19). 3058–3073. 145 indexed citations

19.

Wang, Min, Thomas E. Wales, & Michael C. Fitzgerald. (2006). Conserved thermodynamic contributions of backbone hydrogen bonds in a protein fold. Proceedings of the National Academy of Sciences. 103(8). 2600–2604. 31 indexed citations

20.

Powell, Kendall D., Thomas E. Wales, & Michael C. Fitzgerald. (2002). Thermodynamic stability measurements on multimeric proteins using a new H/D exchange‐ and matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry‐based method. Protein Science. 11(4). 841–851. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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