Rainer Wilcken

3.2k total citations · 1 hit paper
28 papers, 2.3k citations indexed

About

Rainer Wilcken is a scholar working on Molecular Biology, Computational Theory and Mathematics and Organic Chemistry. According to data from OpenAlex, Rainer Wilcken has authored 28 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 10 papers in Computational Theory and Mathematics and 8 papers in Organic Chemistry. Recurrent topics in Rainer Wilcken's work include Computational Drug Discovery Methods (10 papers), Cancer-related Molecular Pathways (8 papers) and Crystallography and molecular interactions (6 papers). Rainer Wilcken is often cited by papers focused on Computational Drug Discovery Methods (10 papers), Cancer-related Molecular Pathways (8 papers) and Crystallography and molecular interactions (6 papers). Rainer Wilcken collaborates with scholars based in Germany, United Kingdom and Switzerland. Rainer Wilcken's co-authors include Frank M. Boeckler, Andreas C. Joerger, Markus O. Zimmermann, Andreas Lange, Alan R. Fersht, Xiangrui Liu, Trevor J. Rutherford, John Spencer, Matthias R. Bauer and Stefan Zahn and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Nucleic Acids Research.

In The Last Decade

Rainer Wilcken

27 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology

2012 1.1k citations Rainer Wilcken, Markus O. Zimmermann et al. Journal of Medicinal Chemistry profile →

Peers

Rainer Wilcken

PTC

ONCOL

Markus O. Zimmermann Germany

M. Stihle Switzerland

Frank M. Boeckler Germany

Zhicai Shang China

Ralf Thoma Switzerland

Yong‐Jun Jiang China

James F. Blake United States

Manuel Ellermann Switzerland

Jian‐Wei Zou China

Bernard Gsell Switzerland

Markus O. Zimmermann Germany

Rainer Wilcken

601 ×0.6

795 ×1.1

743 ×1.1

PTC

190 ×0.4

ONCOL

336 ×0.9

Citations per year, relative to Rainer Wilcken Rainer Wilcken (= 1×) peers Markus O. Zimmermann

Countries citing papers authored by Rainer Wilcken

Since Specialization

Citations

This map shows the geographic impact of Rainer Wilcken's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rainer Wilcken with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rainer Wilcken more than expected).

Fields of papers citing papers by Rainer Wilcken

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rainer Wilcken. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rainer Wilcken. The network helps show where Rainer Wilcken may publish in the future.

Co-authorship network of co-authors of Rainer Wilcken

This figure shows the co-authorship network connecting the top 25 collaborators of Rainer Wilcken. A scholar is included among the top collaborators of Rainer Wilcken based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rainer Wilcken. Rainer Wilcken is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ertl, Peter, Eva Altmann, & Rainer Wilcken. (2025). Ring systems in medicinal chemistry: A cheminformatics analysis of ring popularity in drug discovery over time. European Journal of Medicinal Chemistry. 300. 118178–118178.

Henry, Chrystèle, Callum J. Dickson, Florian Georgescauld, et al.. (2024). Dynamic conformational equilibria in the active states of KRAS and NRAS. RSC Chemical Biology. 6(1). 106–118. 7 indexed citations

Schleberger, Christian, Irina Cornaciu, Rainer Wilcken, et al.. (2020). Fragment‐Based Discovery of Non‐bisphosphonate Binders of Trypanosoma brucei Farnesyl Pyrophosphate Synthase. ChemBioChem. 21(21). 3096–3111. 11 indexed citations

Reinisch, Jens, Michael Diedenhofen, Rainer Wilcken, Anikó Udvarhelyi, & Andreas Glöß. (2019). Benchmarking Different QM Levels for Usage with COSMO-RS. Journal of Chemical Information and Modeling. 59(11). 4806–4813. 25 indexed citations

Pracht, Philipp, Rainer Wilcken, Anikó Udvarhelyi, Stephane Rodde, & Stefan Grimme. (2018). High accuracy quantum-chemistry-based calculation and blind prediction of macroscopic pKa values in the context of the SAMPL6 challenge. Journal of Computer-Aided Molecular Design. 32(10). 1139–1149. 53 indexed citations

Hoegenauer, Klemens, Nicolas Soldermann, Gregory J. Hollingworth, et al.. (2016). Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties. Bioorganic & Medicinal Chemistry Letters. 26(23). 5657–5662. 17 indexed citations

Keller, Marco, Christoph Müller, Rainer Wilcken, et al.. (2015). Arylpiperidines as a new class of oxidosqualene cyclase inhibitors. European Journal of Medicinal Chemistry. 109. 13–22. 9 indexed citations

Joerger, Andreas C., Matthias R. Bauer, Rainer Wilcken, et al.. (2015). Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant p53. Structure. 23(12). 2246–2255. 49 indexed citations

Wilcken, Rainer, Markus O. Zimmermann, Matthias R. Bauer, et al.. (2015). Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere. ACS Chemical Biology. 10(12). 2725–2732. 21 indexed citations

10.

Hurth, Konstanze, et al.. (2015). Regioselective nitration of 3-fluoro-2-substituted benzoic acids. Tetrahedron Letters. 56(22). 2860–2862. 3 indexed citations

11.

Rupp, Matthias, Matthias R. Bauer, Rainer Wilcken, et al.. (2014). Machine Learning Estimates of Natural Product Conformational Energies. PLoS Computational Biology. 10(1). e1003400–e1003400. 30 indexed citations

12.

Zimmermann, Markus O., Andreas Lange, Rainer Wilcken, et al.. (2014). Halogen-Enriched Fragment Libraries as Chemical Probes for Harnessing Halogen Bonding in Fragment-Based Lead Discovery. Future Medicinal Chemistry. 6(6). 617–639. 41 indexed citations

13.

Joerger, Andreas C., Rainer Wilcken, & Antonina Andreeva. (2014). Tracing the Evolution of the p53 Tetramerization Domain. Structure. 22(9). 1301–1310. 30 indexed citations

14.

Liu, Xiangrui, Rainer Wilcken, Andreas C. Joerger, et al.. (2013). Small molecule induced reactivation of mutant p53 in cancer cells. Nucleic Acids Research. 41(12). 6034–6044. 192 indexed citations

15.

Liu, Xiangrui, et al.. (2013). Abstract 2472: Small-molecule-induced reactivation of mutant p53 in cancer cells.. Cancer Research. 73(8_Supplement). 2472–2472. 1 indexed citations

16.

Wilcken, Rainer, Markus O. Zimmermann, Andreas Lange, Stefan Zahn, & Frank M. Boeckler. (2012). Using halogen bonds to address the protein backbone: a systematic evaluation. Journal of Computer-Aided Molecular Design. 26(8). 935–945. 88 indexed citations

17.

Wilcken, Rainer, Markus O. Zimmermann, Andreas Lange, Andreas C. Joerger, & Frank M. Boeckler. (2012). Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology. Journal of Medicinal Chemistry. 56(4). 1363–1388. 1050 indexed citations breakdown →

18.

Wilcken, Rainer, Xiangrui Liu, Markus O. Zimmermann, et al.. (2012). Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53. Journal of the American Chemical Society. 134(15). 6810–6818. 197 indexed citations

19.

Wilcken, Rainer, Markus O. Zimmermann, Andreas Lange, et al.. (2011). Addressing Methionine in Molecular Design through Directed Sulfur–Halogen Bonds. Journal of Chemical Theory and Computation. 7(7). 2307–2315. 48 indexed citations

20.

Mohamed, Heba A., Rainer Wilcken, Matthias R. Bauer, et al.. (2010). Synthesis and Molecular Modeling of Novel Tetrahydro-β-carboline Derivatives with Phosphodiesterase 5 Inhibitory and Anticancer Properties. Journal of Medicinal Chemistry. 54(2). 495–509. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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