Edward C. Twomey

1.5k total citations · 1 hit paper
23 papers, 1.1k citations indexed

About

Edward C. Twomey is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Sensory Systems. According to data from OpenAlex, Edward C. Twomey has authored 23 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 13 papers in Cellular and Molecular Neuroscience and 3 papers in Sensory Systems. Recurrent topics in Edward C. Twomey's work include Neuroscience and Neuropharmacology Research (13 papers), Ion channel regulation and function (7 papers) and Lipid Membrane Structure and Behavior (6 papers). Edward C. Twomey is often cited by papers focused on Neuroscience and Neuropharmacology Research (13 papers), Ion channel regulation and function (7 papers) and Lipid Membrane Structure and Behavior (6 papers). Edward C. Twomey collaborates with scholars based in United States, Russia and Spain. Edward C. Twomey's co-authors include Alexander I. Sobolevsky, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, Appu K. Singh, Luke L. McGoldrick, John R. Engen, Tom A. Rapoport, Scott B. Ficarro and Zhejian Ji and has published in prestigious journals such as Nature, Science and Nature Communications.

In The Last Decade

Edward C. Twomey

20 papers receiving 1.1k citations

Hit Papers

Channel opening and gating mechanism in AMPA-subtype glut... 2017 2026 2020 2023 2017 50 100 150
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Channel opening and gating mechanism in AMPA-subtype glutamate receptors
    2017 183 citations Edward C. Twomey, Maria V. Yelshanskaya et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Edward C. Twomey United States 10 798 514 172 146 84 23 1.1k
Franck C. Chatelain France 19 1.3k 1.6× 569 1.1× 184 1.1× 98 0.7× 60 0.7× 29 1.6k
Manu Ben‐Johny United States 21 1.1k 1.4× 535 1.0× 102 0.6× 132 0.9× 50 0.6× 51 1.4k
Nathaniel Calloway United States 9 582 0.7× 434 0.8× 234 1.4× 168 1.2× 26 0.3× 9 1.1k
George Shapovalov France 20 704 0.9× 268 0.5× 436 2.5× 74 0.5× 58 0.7× 31 1.1k
Yanrui Yang China 16 639 0.8× 323 0.6× 91 0.5× 348 2.4× 52 0.6× 23 1.2k
Amal Kanti Bera India 22 1.1k 1.3× 320 0.6× 44 0.3× 59 0.4× 51 0.6× 59 1.5k
Kimberly A. Clark United States 12 1.0k 1.3× 516 1.0× 129 0.8× 45 0.3× 28 0.3× 18 1.2k
Svetlana B. Tikunova United States 22 937 1.2× 235 0.5× 413 2.4× 96 0.7× 120 1.4× 49 1.6k
Navid Paknejad United States 13 415 0.5× 182 0.4× 164 1.0× 114 0.8× 41 0.5× 17 696
Tsukasa Kusakizako Japan 21 878 1.1× 166 0.3× 199 1.2× 42 0.3× 125 1.5× 33 1.3k

Countries citing papers authored by Edward C. Twomey

Since Specialization
Citations

This map shows the geographic impact of Edward C. Twomey's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward C. Twomey with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward C. Twomey more than expected).

Fields of papers citing papers by Edward C. Twomey

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward C. Twomey. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward C. Twomey. The network helps show where Edward C. Twomey may publish in the future.

Co-authorship network of co-authors of Edward C. Twomey

This figure shows the co-authorship network connecting the top 25 collaborators of Edward C. Twomey. A scholar is included among the top collaborators of Edward C. Twomey based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward C. Twomey. Edward C. Twomey is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Twomey, Edward C., et al.. (2026). Structural basis for activation and conformational plasticity of the GluA4 AMPA receptor. Nature Communications. 17(1).
2.
Qiu, Zhaozhu, et al.. (2025). Structure of transmembrane AMPA receptor regulatory protein subunit γ2. Nature Communications. 16(1). 671–671. 2 indexed citations
3.
Carrillo, Elisa, et al.. (2025). Memantine inhibits calcium-permeable AMPA receptors. Nature Communications. 16(1). 5576–5576.
4.
Ahmed, Fahim, et al.. (2025). Delta-type glutamate receptors are ligand-gated ion channels. Nature. 647(8091). 1063–1071.
5.
Carrillo, Elisa, et al.. (2025). Glutamate gating of AMPA-subtype iGluRs at physiological temperatures. Nature. 641(8063). 788–796. 3 indexed citations
6.
Jayaraman, Vasanthi, et al.. (2024). Allosteric competition and inhibition in AMPA receptors. Nature Structural & Molecular Biology. 31(11). 1669–1679. 5 indexed citations
7.
Twomey, Edward C., et al.. (2023). C-SPAM: an open-source time-resolved specimen vitrification device with light-activated molecules. IUCrJ. 11(1). 16–22. 4 indexed citations
8.
Twomey, Edward C.. (2021). Aboard the ISS: intersubunit signaling revealed in the p97 ATPase. Nature Structural & Molecular Biology. 28(7). 538–539. 1 indexed citations
9.
Twomey, Edward C., Zhejian Ji, Thomas E. Wales, et al.. (2019). Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science. 365(6452). 221 indexed citations
10.
Singh, Appu K., Luke L. McGoldrick, Edward C. Twomey, & Alexander I. Sobolevsky. (2018). Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6. Science Advances. 4(8). eaau6088–eaau6088. 81 indexed citations
11.
Twomey, Edward C., Maria V. Yelshanskaya, Alexander A. Vassilevski, & Alexander I. Sobolevsky. (2018). Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron. 99(5). 956–968.e4. 79 indexed citations
12.
McGoldrick, Luke L., Appu K. Singh, Kei Saotome, et al.. (2017). Opening of the human epithelial calcium channel TRPV6. Nature. 553(7687). 233–237. 157 indexed citations
13.
Twomey, Edward C., Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, & Alexander I. Sobolevsky. (2017). Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron. 94(3). 569–580.e5. 92 indexed citations
14.
Twomey, Edward C., Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, & Alexander I. Sobolevsky. (2017). Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature. 549(7670). 60–65. 183 indexed citations breakdown →
15.
Twomey, Edward C., Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, & Alexander I. Sobolevsky. (2016). Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy. Science. 353(6294). 83–86. 107 indexed citations
16.
Wei, Yufeng & Edward C. Twomey. (2014). NMR spectroscopic characterization of death domain superfamily proteins: Structures, dynamics and interactions. 83–110. 1 indexed citations
17.
18.
Twomey, Edward C., et al.. (2013). Substantial Conformational Change Mediated by Charge-Triad Residues of the Death Effector Domain in Protein-Protein Interactions. PLoS ONE. 8(12). e83421–e83421. 5 indexed citations
19.
Twomey, Edward C. & Yufeng Wei. (2012). High-definition NMR structure of PED/PEA-15 death effector domain reveals details of key polar side chain interactions. Biochemical and Biophysical Research Communications. 424(1). 141–146. 11 indexed citations
20.
Twomey, Edward C., et al.. (2012). Profound conformational changes of PED/PEA-15 in ERK2 complex revealed by NMR backbone dynamics. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1824(12). 1382–1393. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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