Douglas L. Rothman

50.6k total citations · 13 hit papers
408 papers, 38.9k citations indexed

About

Douglas L. Rothman is a scholar working on Radiology, Nuclear Medicine and Imaging, Cellular and Molecular Neuroscience and Molecular Biology. According to data from OpenAlex, Douglas L. Rothman has authored 408 papers receiving a total of 38.9k indexed citations (citations by other indexed papers that have themselves been cited), including 200 papers in Radiology, Nuclear Medicine and Imaging, 128 papers in Cellular and Molecular Neuroscience and 92 papers in Molecular Biology. Recurrent topics in Douglas L. Rothman's work include Advanced MRI Techniques and Applications (195 papers), Neuroscience and Neuropharmacology Research (115 papers) and Advanced NMR Techniques and Applications (66 papers). Douglas L. Rothman is often cited by papers focused on Advanced MRI Techniques and Applications (195 papers), Neuroscience and Neuropharmacology Research (115 papers) and Advanced NMR Techniques and Applications (66 papers). Douglas L. Rothman collaborates with scholars based in United States, Denmark and Canada. Douglas L. Rothman's co-authors include Robert G. Shulman, Gerald I. Shulman, Kevin L. Behar, Fahmeed Hyder, Graeme F. Mason, Kitt Falk Petersen, Gary W. Cline, Ognen A. C. Petroff, Robin A. de Graaf and Sylvie Dufour and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Douglas L. Rothman

399 papers receiving 38.1k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance

2003 1.7k citations Kitt Falk Petersen, Douglas E. Befroy et al. profile →
Mechanism of free fatty acid-induced insulin resistance in humans.

1996 1.2k citations Thomas B. Price, Douglas L. Rothman et al. Journal of Clinical Investigation profile →
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1 H NMR spectroscopy study

1999 996 citations Kitt Falk Petersen, Douglas L. Rothman et al. profile →
Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by¹³C Nuclear Magnetic Resonance Spectroscopy

1990 988 citations Gerald I. Shulman, Douglas L. Rothman et al. profile →
Effects of free fatty acids on glucose transport and IRS-1–associated phosphatidylinositol 3-kinase activity

1999 974 citations Sylvie Dufour, Gary W. Cline et al. Journal of Clinical Investigation profile →
Energy on Demand

1999 900 citations Douglas L. Rothman, Robert G. Shulman et al. profile →
Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

1998 665 citations Graeme F. Mason, Douglas L. Rothman et al. Proceedings of the National Academy of Sciences profile →
Subtype-Specific Alterations of γ-Aminobutyric Acid and Glutamatein Patients With Major Depression

2004 649 citations Gerard Sanacora, Ralitza Gueorguieva et al. profile →
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.

1992 612 citations Douglas L. Rothman, Robert G. Shulman et al. Journal of Clinical Investigation profile →
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome

2007 558 citations Kitt Falk Petersen, Sylvie Dufour et al. Proceedings of the National Academy of Sciences profile →
Increased Glucose Transport–Phosphorylation and Muscle Glycogen Synthesis after Exercise Training in Insulin-Resistant Subjects

1996 520 citations Thomas B. Price, Kitt Falk Petersen et al. profile →
Impaired Glucose Transport as a Cause of Decreased Insulin-Stimulated Muscle Glycogen Synthesis in Type 2 Diabetes

1999 515 citations Gary W. Cline, Kitt Falk Petersen et al. profile →
Reduced Cortical γ-Aminobutyric Acid Levels in Depressed Patients Determined by Proton Magnetic Resonance Spectroscopy

1999 514 citations Gerard Sanacora, Graeme F. Mason et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Douglas L. Rothman United States	99	11.2k	11.2k	10.8k	9.3k	5.8k	408	38.9k
Robert G. Shulman United States	82	7.6k 0.7×	7.8k 0.7×	3.9k 0.4×	4.7k 0.5×	4.0k 0.7×	256	22.4k
Benjamin F. Cravatt United States	128	2.3k 0.2×	26.4k 2.4×	4.7k 0.4×	11.6k 1.2×	4.3k 0.7×	583	60.0k
Henrik Zetterberg Sweden	135	5.0k 0.4×	26.3k 2.4×	46.4k 4.3×	10.8k 1.2×	7.3k 1.2×	2.0k	96.1k
Colin L. Masters Australia	135	3.9k 0.4×	31.1k 2.8×	52.1k 4.8×	9.5k 1.0×	5.4k 0.9×	1.1k	82.7k
Kaj Blennow Sweden	158	6.7k 0.6×	33.4k 3.0×	65.7k 6.1×	13.3k 1.4×	10.5k 1.8×	2.0k	122.7k
David M. Holtzman United States	166	4.8k 0.4×	27.2k 2.4×	53.8k 5.0×	15.7k 1.7×	13.2k 2.3×	580	99.8k
Bo K. Siesjö Sweden	98	4.0k 0.4×	12.3k 1.1×	6.3k 0.6×	13.2k 1.4×	1.4k 0.2×	438	36.2k
Brian K. Kobilka United States	128	7.1k 0.6×	51.2k 4.6×	4.4k 0.4×	29.9k 3.2×	898 0.2×	363	61.3k
Bryan L. Roth United States	112	2.1k 0.2×	27.6k 2.5×	4.0k 0.4×	24.1k 2.6×	5.0k 0.9×	503	50.5k
Bradley T. Hyman United States	156	9.0k 0.8×	32.6k 2.9×	60.6k 5.6×	23.1k 2.5×	18.4k 3.2×	730	114.1k

Countries citing papers authored by Douglas L. Rothman

Since Specialization

Citations

This map shows the geographic impact of Douglas L. Rothman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas L. Rothman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas L. Rothman more than expected).

Fields of papers citing papers by Douglas L. Rothman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas L. Rothman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas L. Rothman. The network helps show where Douglas L. Rothman may publish in the future.

Co-authorship network of co-authors of Douglas L. Rothman

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas L. Rothman. A scholar is included among the top collaborators of Douglas L. Rothman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas L. Rothman. Douglas L. Rothman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Mangia, Silvia, Mauro DiNuzzo, Sara Ponticorvo, et al.. (2025). Reduced removal of waste products from energy metabolism takes center stage in human brain aging. Scientific Reports. 15(1). 8127–8127.

Swanberg, Kelley M., Hetty Prinsen, Christopher L. Averill, et al.. (2024). Medial prefrontal cortex neurotransmitter abnormalities in posttraumatic stress disorder with and without comorbidity to major depression. NMR in Biomedicine. 37(11). e5220–e5220.

DiNuzzo, Mauro, Gerald A. Dienel, Kevin L. Behar, et al.. (2023). Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO₂, and pO₂. Journal of Neurochemistry. 168(5). 632–662. 17 indexed citations

Rothman, Douglas L., Peter B. Moore, & Robert G. Shulman. (2023). The impact of metabolism on the adaptation of organisms to environmental change. Frontiers in Cell and Developmental Biology. 11. 1197226–1197226. 9 indexed citations

Averill, Lynnette A., Lihong Jiang, Prerana Purohit, et al.. (2022). Prefrontal Glutamate Neurotransmission in PTSD: A Novel Approach to Estimate Synaptic Strength in Vivo in Humans. SHILAP Revista de lepidopterología. 6. 2290714494–2290714494. 13 indexed citations

Averill, Lynnette A., Chadi G. Abdallah, Lisa R. Fenton, et al.. (2020). Early life stress and glutamate neurotransmission in major depressive disorder. European Neuropsychopharmacology. 35. 71–80. 16 indexed citations

Nozaki, Yuichi, Max C. Petersen, Dongyan Zhang, et al.. (2020). Metabolic control analysis of hepatic glycogen synthesis in vivo. Proceedings of the National Academy of Sciences. 117(14). 8166–8176. 64 indexed citations

Walsh, John J., Yuegao Huang, John W. Simmons, et al.. (2019). Dynamic Thermal Mapping of Localized Therapeutic Hypothermia in the Brain. Journal of Neurotrauma. 37(1). 55–65. 9 indexed citations

Abdallah, Chadi G., Lihong Jiang, Henk M. De Feyter, et al.. (2014). Glutamate Metabolism in Major Depressive Disorder. American Journal of Psychiatry. 171(12). 1320–1327. 132 indexed citations

10.

Pugh, Kenneth R., Stephen J. Frost, Douglas L. Rothman, et al.. (2014). Glutamate and Choline Levels Predict Individual Differences in Reading Ability in Emergent Readers. Journal of Neuroscience. 34(11). 4082–4089. 62 indexed citations

11.

Befroy, Douglas E., Douglas L. Rothman, Kitt Falk Petersen, & Gerald I. Shulman. (2012). 31P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism. Diabetes. 61(11). 2669–2678. 44 indexed citations

12.

Hyder, Fahmeed, Péter Hermán, Basavaraju G. Sanganahalli, et al.. (2011). Role of Ongoing, Intrinsic Activity of Neuronal Populations for Quantitative Neuroimaging of Functional Magnetic Resonance Imaging–Based Networks. Brain Connectivity. 1(3). 185–193. 11 indexed citations

13.

Savage, David B., Sylvie Dufour, Nadia Schoenmakers, et al.. (2010). Resistance to thyroid hormone is associated with raised energy expenditure, muscle mitochondrial uncoupling, and hyperphagia. Journal of Clinical Investigation. 120(4). 1345–1354. 90 indexed citations

14.

Boumezbeur, Fawzi, Graeme F. Mason, Robin A. de Graaf, et al.. (2009). Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy. Journal of Cerebral Blood Flow & Metabolism. 30(1). 211–221. 182 indexed citations

15.

Chahboune, Halima, Laura R. Ment, William Stewart, et al.. (2009). Hypoxic Injury during Neonatal Development in Murine Brain: Correlation between In Vivo DTI Findings and Behavioral Assessment. Cerebral Cortex. 19(12). 2891–2901. 50 indexed citations

16.

Befroy, Douglas E., Kitt Falk Petersen, Sylvie Dufour, et al.. (2008). Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals. Proceedings of the National Academy of Sciences. 105(43). 16701–16706. 80 indexed citations

17.

Sanacora, Gerard, Lisa R. Fenton, Madonna Fasula, et al.. (2005). Cortical γ-Aminobutyric Acid Concentrations in Depressed Patients Receiving Cognitive Behavioral Therapy. Biological Psychiatry. 59(3). 284–286. 70 indexed citations

18.

Shulman, Robert G. & Douglas L. Rothman. (2005). Metabolomics by in vivo NMR. J. Wiley eBooks. 8 indexed citations

19.

Price, Thomas B., Douglas L. Rothman, & Robert G. Shulman. (1999). NMR of glycogen in exercise. Proceedings of The Nutrition Society. 58(4). 851–859. 21 indexed citations

20.

Rothman, Douglas L., et al.. (1990). 13C NMR studies of glucose disposal in normal and non-insulin-dependent diabetic humans. Philosophical Transactions of the Royal Society of London Series A Physical and Engineering Sciences. 333(1632). 525–529. 4 indexed citations

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