Douglas E. Befroy

12.5k total citations · 8 hit papers
38 papers, 9.9k citations indexed

About

Douglas E. Befroy is a scholar working on Physiology, Molecular Biology and Epidemiology. According to data from OpenAlex, Douglas E. Befroy has authored 38 papers receiving a total of 9.9k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Physiology, 17 papers in Molecular Biology and 9 papers in Epidemiology. Recurrent topics in Douglas E. Befroy's work include Adipose Tissue and Metabolism (16 papers), Advanced MRI Techniques and Applications (8 papers) and Mitochondrial Function and Pathology (7 papers). Douglas E. Befroy is often cited by papers focused on Adipose Tissue and Metabolism (16 papers), Advanced MRI Techniques and Applications (8 papers) and Mitochondrial Function and Pathology (7 papers). Douglas E. Befroy collaborates with scholars based in United States, United Kingdom and Denmark. Douglas E. Befroy's co-authors include Gerald I. Shulman, Kitt Falk Petersen, Sylvie Dufour, Gary W. Cline, Douglas L. Rothman, Charlotte E. Ariyan, James Dziura, Loretta DiPietro, Stefan Bilz and Varman T. Samuel and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Douglas E. Befroy

38 papers receiving 9.6k citations

Hit Papers

Impaired Mitochondrial Activity in the Insulin-Resistant ... 2002 2026 2010 2018 2004 2003 2004 2005 2002 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
    2004 1.7k citations Kitt Falk Petersen, Sylvie Dufour et al. New England Journal of Medicine profile →
  2. Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
    2003 1.7k citations Kitt Falk Petersen, Douglas E. Befroy et al. Science profile →
  3. Mechanism of Hepatic Insulin Resistance in Non-alcoholic Fatty Liver Disease
    2004 1.0k citations Varman T. Samuel, Xianqin Qu et al. Journal of Biological Chemistry profile →
  4. Reversal of Nonalcoholic Hepatic Steatosis, Hepatic Insulin Resistance, and Hyperglycemia by Moderate Weight Reduction in Patients With Type 2 Diabetes
    2005 688 citations Kitt Falk Petersen, Sylvie Dufour et al. Diabetes profile →
  5. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
    2002 581 citations Kitt Falk Petersen, Elif A Oral et al. Journal of Clinical Investigation profile →
  6. The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome
    2007 558 citations Kitt Falk Petersen, Sylvie Dufour et al. Proceedings of the National Academy of Sciences profile →
  7. The Effects of Rosiglitazone on Insulin Sensitivity, Lipolysis, and Hepatic and Skeletal Muscle Triglyceride Content in Patients With Type 2 Diabetes
    2002 536 citations Sylvie Dufour, Douglas E. Befroy et al. Diabetes profile →
  8. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
    2002 503 citations Kitt Falk Petersen, Elif A Oral et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Douglas E. Befroy United States 29 5.2k 4.2k 3.5k 2.2k 1.1k 38 9.9k
Kurt Højlund Denmark 54 6.6k 1.3× 4.9k 1.2× 2.4k 0.7× 1.6k 0.7× 1.0k 0.9× 214 11.5k
Dongyan Zhang United States 42 4.0k 0.8× 4.6k 1.1× 3.3k 0.9× 2.2k 1.0× 1.6k 1.4× 63 9.1k
Niels Jessen Denmark 53 4.2k 0.8× 3.8k 0.9× 1.6k 0.5× 2.1k 0.9× 1.7k 1.6× 234 9.4k
P. Nowotny Austria 49 4.0k 0.8× 3.3k 0.8× 2.2k 0.6× 2.9k 1.3× 1.6k 1.4× 204 9.2k
David B. Savage United Kingdom 47 3.5k 0.7× 4.3k 1.0× 3.0k 0.9× 1.7k 0.8× 1.3k 1.1× 96 8.9k
A. B. Jenkins Australia 46 5.0k 1.0× 2.8k 0.7× 1.7k 0.5× 2.3k 1.0× 1.1k 1.0× 114 9.0k
Jürgen Machann Germany 61 4.8k 0.9× 2.5k 0.6× 4.6k 1.3× 2.7k 1.2× 1.7k 1.5× 234 11.7k
Gianluca Perseghin Italy 48 3.4k 0.7× 2.2k 0.5× 3.7k 1.1× 3.0k 1.4× 1.7k 1.5× 193 9.6k
Gary Sweeney Canada 57 3.8k 0.7× 3.7k 0.9× 3.5k 1.0× 987 0.4× 1.3k 1.1× 180 9.9k
Yves Deshaies Canada 47 3.5k 0.7× 2.2k 0.5× 2.2k 0.6× 1.4k 0.6× 867 0.8× 181 7.3k

Countries citing papers authored by Douglas E. Befroy

Since Specialization
Citations

This map shows the geographic impact of Douglas E. Befroy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas E. Befroy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas E. Befroy more than expected).

Fields of papers citing papers by Douglas E. Befroy

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas E. Befroy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas E. Befroy. The network helps show where Douglas E. Befroy may publish in the future.

Co-authorship network of co-authors of Douglas E. Befroy

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas E. Befroy. A scholar is included among the top collaborators of Douglas E. Befroy based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas E. Befroy. Douglas E. Befroy is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lievens, Eline, et al.. (2021). CORP: quantification of human skeletal muscle carnosine concentration by proton magnetic resonance spectroscopy. Journal of Applied Physiology. 131(1). 250–264. 12 indexed citations
2.
Krššák, Martin, Lucas Lindeboom, Vera B. Schrauwen‐Hinderling, et al.. (2020). Proton magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations. NMR in Biomedicine. 34(5). e4266–e4266. 55 indexed citations
3.
Rutkowsky, Jennifer M., Michelle Puchowicz, Mari S. Golub, et al.. (2018). Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet. PLoS ONE. 13(2). e0191909–e0191909. 48 indexed citations
4.
Petersen, Kitt Falk, Douglas E. Befroy, Sylvie Dufour, Douglas L. Rothman, & Gerald I. Shulman. (2016). Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by 13C Magnetic Resonance Spectroscopy. Cell Metabolism. 24(1). 167–171. 61 indexed citations
5.
Befroy, Douglas E., Rachel J. Perry, Nimit Jain, et al.. (2013). Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy. Nature Medicine. 20(1). 98–102. 72 indexed citations
6.
Befroy, Douglas E., Douglas L. Rothman, Kitt Falk Petersen, & Gerald I. Shulman. (2012). 31P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism. Diabetes. 61(11). 2669–2678. 44 indexed citations
7.
Alves, Tiago C., Douglas E. Befroy, Richard G. Kibbey, et al.. (2011). Regulation of hepatic fat and glucose oxidation in rats with lipid-induced hepatic insulin resistance. Hepatology. 53(4). 1175–1181. 41 indexed citations
8.
Savage, David B., Sylvie Dufour, Nadia Schoenmakers, et al.. (2010). Resistance to thyroid hormone is associated with raised energy expenditure, muscle mitochondrial uncoupling, and hyperphagia. Journal of Clinical Investigation. 120(4). 1345–1354. 90 indexed citations
9.
Tevald, Michael A., Ian R. Lanza, Douglas E. Befroy, & Jane A. Kent‐Braun. (2009). Intramyocellular oxygenation during ischemic muscle contractions in vivo. European Journal of Applied Physiology. 106(3). 333–343. 9 indexed citations
10.
Befroy, Douglas E., Kitt Falk Petersen, Douglas L. Rothman, & Gerald I. Shulman. (2009). Chapter 21 Assessment of In Vivo Mitochondrial Metabolism by Magnetic Resonance Spectroscopy. Methods in enzymology on CD-ROM/Methods in enzymology. 457. 373–393. 32 indexed citations
11.
Befroy, Douglas E., Kitt Falk Petersen, Sylvie Dufour, et al.. (2008). Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals. Proceedings of the National Academy of Sciences. 105(43). 16701–16706. 80 indexed citations
12.
Choi, Cheol Soo, Douglas E. Befroy, Roberto Codella, et al.. (2008). Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism. Proceedings of the National Academy of Sciences. 105(50). 19926–19931. 228 indexed citations
13.
Petersen, Kitt Falk, Sylvie Dufour, David B. Savage, et al.. (2007). The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proceedings of the National Academy of Sciences. 104(31). 12587–12594. 558 indexed citations breakdown →
14.
Lanza, Ian R., Danielle M. Wigmore, Douglas E. Befroy, & Jane A. Kent‐Braun. (2006). In vivo ATP production during free‐flow and ischaemic muscle contractions in humans. The Journal of Physiology. 577(1). 353–367. 76 indexed citations
15.
Lanza, Ian R., Douglas E. Befroy, & Jane A. Kent‐Braun. (2005). Age-related changes in ATP-producing pathways in human skeletal muscle in vivo. Journal of Applied Physiology. 99(5). 1736–1744. 151 indexed citations
16.
Petersen, Kitt Falk, et al.. (2004). Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes. New England Journal of Medicine. 350(7). 664–671. 1701 indexed citations breakdown →
17.
Samuel, Varman T., Xianqin Qu, Benjamin D. Elder, et al.. (2004). Mechanism of Hepatic Insulin Resistance in Non-alcoholic Fatty Liver Disease. Journal of Biological Chemistry. 279(31). 32345–32353. 1040 indexed citations breakdown →
18.
Petersen, Kitt Falk, Douglas E. Befroy, Sylvie Dufour, et al.. (2003). Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance. Science. 300(5622). 1140–1142. 1657 indexed citations breakdown →
19.
Petersen, Kitt Falk, Elif A Oral, Sylvie Dufour, et al.. (2002). Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. Journal of Clinical Investigation. 109(10). 1345–1350. 44 indexed citations
20.
Petersen, Kitt Falk, Elif A Oral, Sylvie Dufour, et al.. (2002). Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. Journal of Clinical Investigation. 109(10). 1345–1350. 503 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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