David B. Savage

21.5k citations

96 papers · 8.9k indexed · 3 hit papers · h-index 47

Impact in

Biochemistry top 0.1%
- Lipid metabolism and biosynthesis
Physiology top 0.5%
- Adipose Tissue and Metabolism

Papers in

Biochemistry 19
- Lipid metabolism and biosynthesis 19
Physiology 48
- Adipose Tissue and Metabolism 42

Co-authors: Stephen O’Rahilly Gerald I. Shulman Kitt Falk Petersen Robert K. Semple Krishna Chatterjee Antonio Vidal‐Puig Ciaran Sewter Phillip Görden
Journals: The Journal of Clinical Endocrinology & Metabolism (10 papers)Diabetes (7 papers)Journal of Clinical Investigation (7 papers)Proceedings of the National Academy of Sciences (5 papers)Cell Reports (3 papers)
Partner nations: United Kingdom United States France

In The Last Decade

David B. Savage

95 papers receiving 8.7k citations

Hit Papers

align trajectories log scale

The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome 2007 · 558 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2007 Proceedings of the National Academy of Sciences
2007 Physiological Reviews
2001 Diabetes

Peers

Countries citing papers authored by David B. Savage

Since Specialization

Citations

This map shows the geographic impact of David B. Savage's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David B. Savage with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David B. Savage more than expected).

Fields of papers citing papers by David B. Savage

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David B. Savage. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David B. Savage. The network helps show where David B. Savage may publish in the future.

Co-authors

The 25 scholars most cited alongside David B. Savage, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David B. Savage Line = papers co-authored together David B. Savage links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The role of lipid droplet associated proteins in inherited human disorders FEBS Letters ·Xiaowen Duan, David B. Savage	2023	4
2	The architecture of Cidec-mediated interfaces between lipid droplets Cell Reports ·Iva Ganeva, Koini Lim, Jérôme Boulanger, Patrick C. Hoffmann, Olivia Muriel, Alicia C. Borgeaud, Wim J. H. Hagen, David B. Savage, Wanda Kukulski	2023	12
3	Dual binding motifs underpin the hierarchical association of perilipins1–3 with lipid droplets Molecular Biology of the Cell ·Dalila Ajjaji, Kalthoum Ben M’Barek, Michael L. Mimmack, Cheryl England, Haya Herscovitz, Liang Dong, Richard G. Kay, Satish Patel, Vladimı́r Saudek, Donald Small, David B. Savage, Abdou Rachid Thiam	2019	44
4	Lipase tug of war: PNPLA3 sequesters ABHD5 from ATGL Nature Metabolism ·Stefano Romeo, David B. Savage	2019	5
5	Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis Scientific Reports ·Ajay Thankamony, Graham J. Kemp, Albert Koulman, Vlada Bokii, David B. Savage, Chris Boesch, Leanne Hodson, David B. Dunger, Alison Sleigh	2018	5
6	European paediatric non-alcoholic fatty liver disease registry (EU-PNAFLD): Design and rationale Contemporary Clinical Trials ·Jake P. Mann, Anita Vreugdenhil, Piotr Socha, Wojciech Jańczyk, Ulrich Baumann, Sanjay Rajwal, Thomas Casswall, Claude Marcus, Indra van Mourik, Stephen O’Rahilly, David B. Savage, G. Noble-Jamieson, Florence Lacaille, M. Dabbas, Béatrice Dubern, Déirdre Kelly, Valério Nobili, Quentin M. Anstee	2018	11
7	PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress Developmental Cell ·Afreen Haider, Yu‐Chen Wei, Koini Lim, António Daniel Barbosa, Che Liu, Ursula Weber, Marek Mlodzik, Kadri Oras, Simon Collier, M. Mahmood Hussain, Liang Dong, Satish Patel, Anna Álvarez-Guaita, Vladimı́r Saudek, Benjamin Jenkins, Albert Koulman, Marcus K. Dymond, Roger Hardie, Symeon Siniossoglou, David B. Savage	2018	105
8	The genetics of lipid storage and human lipodystrophies Trends in Molecular Medicine ·Ann L. Robbins, David B. Savage	2015	56
9	Familial partial lipodystrophy linked to a novel peroxisome proliferator activator receptor-[gamma] mutation, H449L Endocrine Abstracts ·Tevfik Demir, Hüseyin Önay, David B. Savage, Ayse Kubat Kuruuzum, Şenay Savaş Erdeve, Canan Altay, Samim Özen, Leyla Demir, Ümit Çavdar, Barış Akıncı	2015	1
10	Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance Journal of Clinical Investigation ·Felicity Payne, Rita Colnaghi, Nuno Rocha, Asha Seth, J. Ieuan Harris, Gillian Carpenter, William Bottomley, Eleanor Wheeler, Stephen Q. Wong, Vladimı́r Saudek, David B. Savage, Stephen O’Rahilly, Jean‐Claude Carel, Inês Barroso, Mark O’Driscoll, Robert K. Semple	2014	72
11	An Activating Mutation of AKT2 and Human Hypoglycemia Science ·Khalid Hussain, Benjamin Challis, Nuno Rocha, Felicity Payne, Marina Minic, Alastair Thompson, Allan Daly, Clare L. Scott, Jeffrey R. Harris, B. J. L. Smillie, David B. Savage, Uma Ramaswami, Pascale de Lonlay, Stephen O’Rahilly, Inês Barroso, Robert K. Semple	2011	114
12	Resistance to thyroid hormone is associated with raised energy expenditure, muscle mitochondrial uncoupling, and hyperphagia Journal of Clinical Investigation ·Catherine S. Mitchell, David B. Savage, Sylvie Dufour, Nadia Schoenmakers, Peter R. Murgatroyd, Douglas E. Befroy, David Halsall, Samantha Northcott, Philippa Raymond‐Barker, Suzanne Curran, Elana Henning, Julia M. Keogh, Penny Owen, John H. Lazarus, Douglas L. Rothman, I. Sadaf Farooqi, Gerald I. Shulman, Krishna Chatterjee, Kitt Falk Petersen	2010	90
13	Lipodystrophy: metabolic insights from a rare disorder Journal of Endocrinology ·Isabel Huang‐Doran, Alison Sleigh, Justin J. Rochford, Stephen O’Rahilly, David B. Savage	2010	156
14	A Prevalent Variant in PPP1R3A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice Oxford University Research Archive (ORA) (University of Oxford) ·David B. Savage, Lanmin Zha, Ravikumar Balasubramanian, Cheol Soo Choi, J.E.M. Snaar, Amanda C McGuire, Sung-Eun Wou, Gema Medina‐Gómez, Sheene Kim, Cheryl B. Bock, Dyann M. Segvich, Antonio Vidal‐Puig, Nicholas J. Wareham, Gerald I. Shulman, Fredrik Karpe, Roy Taylor, Bartholomew A. Pederson, Peter J. Roach, Stephen O’Rahilly, Anna Depaoli-Roach	2008	15
15	A Prevalent Variant in PPP1R3A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice PLoS Medicine ·David B. Savage, Lanmin Zhai, Ravikumar Balasubramanian, Cheol Soo Choi, J.E.M. Snaar, Amanda C McGuire, Sung-Eun Wou, Gema Medina‐Gómez, Sheene Kim, Cheryl B. Bock, Dyann M. Segvich, Antonio Vidal‐Puig, Nicholas J. Wareham, Gerald I. Shulman, Fredrik Karpe, Roy Taylor, Bartholomew A. Pederson, Peter J. Roach, Stephen O’Rahilly, Anna Depaoli-Roach	2008	41
16	The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome Proceedings of the National Academy of Sciences ·Kitt Falk Petersen, Sylvie Dufour, David B. Savage, Stefan Bilz, Gina Solomon, Shin Yonemitsu, Gary W. Cline, Douglas E. Befroy, Laura Zemany, Barbara B. Kahn, Xenophon Papademetris, Douglas L. Rothman, Gerald I. Shulman Hit paper breakdown →	2007	558
17	Suppression of Diacylglycerol Acyltransferase-2 (DGAT2), but Not DGAT1, with Antisense Oligonucleotides Reverses Diet-induced Hepatic Steatosis and Insulin Resistance Journal of Biological Chemistry ·Cheol Soo Choi, David B. Savage, Ameya Kulkarni, Xing Yu, Zhenxiang Liu, Katsutaro Morino, Sheene Kim, Alberto Distefano, Varman T. Samuel, Susanne Neschen, Dongyan Zhang, Amy Wang, Xian‐Man Zhang, Mario Kahn, Gary W. Cline, Sanjay K. Pandey, John G. Geisler, Sanjay Bhanot, Brett P. Monia, Gerald I. Shulman	2007	312
18	Disordered Lipid Metabolism and the Pathogenesis of Insulin Resistance Physiological Reviews ·David B. Savage, Kitt Falk Petersen, Gerald I. Shulman Hit paper breakdown →	2007	826
19	Activation of the farnesoid X receptor improves lipid metabolism in combined hyperlipidemic hamsters American Journal of Physiology-Endocrinology and Metabolism ·Stefan Bilz, Varman T. Samuel, Katsutaro Morino, David B. Savage, Cheol Soo Choi, Gerald I. Shulman	2005	76
20	Leptin: a novel therapeutic role in lipodystrophy Journal of Clinical Investigation ·David B. Savage, Stephen O’Rahilly	2002	22

About David B. Savage

David B. Savage is a scholar working on Biochemistry, Physiology, Endocrine and Autonomic Systems, Molecular Biology and Cell Biology, having authored 96 papers that have together received 8.9k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (42 papers), Nuclear Structure and Function (31 papers), Metabolism, Diabetes, and Cancer (22 papers), Lipid metabolism and biosynthesis (19 papers), Peroxisome Proliferator-Activated Receptors (15 papers), Adipokines, Inflammation, and Metabolic Diseases (10 papers), Liver Disease Diagnosis and Treatment (10 papers) and Diabetes and associated disorders (9 papers). The work is most often cited by research in Biochemistry (1.3k citations), Physiology (3.5k citations), Endocrine and Autonomic Systems (715 citations), Endocrinology, Diabetes and Metabolism (1.7k citations) and Epidemiology (3.0k citations). David B. Savage has collaborated with scholars based in United Kingdom, United States and France. Frequent co-authors include Stephen O’Rahilly, Gerald I. Shulman, Kitt Falk Petersen, Robert K. Semple, Krishna Chatterjee, Antonio Vidal‐Puig, Ciaran Sewter, Phillip Görden, Elaine Cochran and Robert V. Considine. Their work appears in journals such as The Journal of Clinical Endocrinology & Metabolism, Diabetes, Journal of Clinical Investigation, Proceedings of the National Academy of Sciences and Cell Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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