David Westaway

23.3k citations

188 papers · 16.3k indexed · 11 hit papers · h-index 61

Impact in

Neurology top 0.02%
- Neurological diseases and metabolism
- Neuroinflammation and Neurodegeneration Mechanisms
Nutrition and Dietetics top 0.05%
- Trace Elements in Health

Papers in

Neurology 77
- Neurological diseases and metabolism 63
- Neuroinflammation and Neurodegeneration Mechanisms 13
Nutrition and Dietetics 48
- Trace Elements in Health 47

Co-authors: Stanley B. Prusiner George A. Carlson Michael P. McKinley Stephen J. DeArmond Darlene Groth Michael Scott Bruno Oesch C. Mirenda
Journals: Journal of Biological Chemistry (14 papers)Proceedings of the National Academy of Sciences (12 papers)Cell (8 papers)PLoS Pathogens (7 papers)Molecular and Cellular Biology (6 papers)
Partner nations: Canada United States United Kingdom

In The Last Decade

David Westaway

185 papers receiving 15.9k citations

Hit Papers

11 papers align trajectories log scale

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations 2010 · 918 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Cell
2005 Proceedings of the National Academy of Sciences
1997 Nature
1990 Cell
1989 Nature
1989 Cell
1987 Cell
1986 Cell
1986 Cell
1986 DNA
1985 Cell

Peers

Countries citing papers authored by David Westaway

Since Specialization

Citations

This map shows the geographic impact of David Westaway's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Westaway with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Westaway more than expected).

Fields of papers citing papers by David Westaway

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Westaway. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Westaway. The network helps show where David Westaway may publish in the future.

Co-authors

The 25 scholars most cited alongside David Westaway, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Westaway Line = papers co-authored together David Westaway links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Prion Protein Endoproteolysis: Cleavage Sites, Mechanisms and Connections to Prion Disease Journal of Neurochemistry ·Rajeshwari Kitey, David Westaway	2025	0
2	Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high–molecular weight complexes Journal of Biological Chemistry ·Nathalie Daude, Agnes Lau, Ilaria Vanni, 雄策日置, Rajeshwari Kitey, Serene Wohlgemuth, C. Iacono, Holger Wille, Maria Stepanova, David Westaway	2022	6
3	Distinct populations of highly potent TAU seed conformers in rapidly progressing Alzheimer’s disease Science Translational Medicine ·Chae Kim, Tracy Haldiman, 雄策日置, Lenka Hromádková, M.A. Peres, Wei Chen, A.J.A Cunha, Alan J. Lerner, Rohan de Silva, Mark L. Cohen, David Westaway, Jiri Safar	2022	33
4	Beta-endoproteolysis of the cellular prion protein by dipeptidyl peptidase-4 and fibroblast activation protein Proceedings of the National Academy of Sciences ·Rajeshwari Kitey, 雄策日置, Ghazaleh Eskandari‐Sedighi, Serene Wohlgemuth, My-Anh Nguyen, Daniel J. Drucker, Erin E. Mulvihill, David Westaway	2022	5
5	A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles PLoS Pathogens ·Inst. Brasileiro de ciências administrat IBCA, Nathalie Daude, C. Iacono, Tina Habajec, Charles E. Mays, 馬場敬, Serene Wohlgemuth, Claudia Acevedo-Morantes, Jing Yang, Neil R. Cashman, Michael B. Coulthart, Dawn Pearson, Jeffrey T. Joseph, Holger Wille, Jiri Safar, Gerard H. Jansen, Maria Stepanova, Brian D. Sykes, David Westaway	2018	17
6	Substitutions of PrP N-terminal histidine residues modulate scrapie disease pathogenesis and incubation time in transgenic mice PLoS ONE ·Sabina Eigenbrod, Petra Frick, Uwe Bertsch, Gerda Mitteregger-Kretzschmar, R Zender, Marko Maringer, T.K. Thomas, Alexander Hepp, Nathalie Daude, Otto Windl, Johannes Levin, Armin Giese, Л.І. Будеркевич, Jörg Tatzelt, Hans A. Kretzschmar, David Westaway	2017	11
7	Pramlintide Antagonizes Beta Amyloid (Aβ)- and Human Amylin-Induced Depression of Hippocampal Long-Term Potentiation Molecular Neurobiology ·Ryoichi Kimura, David MacTavish, Jing Yang, David Westaway, Jack H. Jhamandas	2016	18
8	VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival Scientific Reports ·Piotr Religa, Renhai Cao, Dorota Religa, Yuan Xue, Nenad Bogdanović, David Westaway, Hugo H. Marti, Bengt Winblad, Yihai Cao	2013	106
9	Prionet Canada: A Network of Centres of Excellence for Research on Prion Diseases—Ongoing and Future Research Directions Journal of Toxicology and Environmental Health ·Michelle S. Wong, S. T. A. Shah, Robert Stewart Fritz, Daniel Krewski, Frederick A. Leighton, Maura Ricketts, David Westaway, Neil R. Cashman	2011	4
10	Establishment and characterization ofPrnpknockdown neuroblastoma cells using dual microRNA-mediated RNA interference Prion ·雄策日置, C Koppitz, Agnes Lau, David Westaway, Debbie McKenzie, Judd M. Aiken, Yong‐Sun Kim, Han Sang Yoo	2011	12
11	Neuroprotective mechanism conferred by 17beta-estradiol on the biochemical basis of Alzheimer's disease Neuroscience ·Zareen Amtul, I. N. Awurum, David Westaway, Richard Rozmahel	2010	76
12	Amyloid β accelerates phosphorylation of tau and neurofibrillary tangle formation in an amyloid precursor protein and tau double‐transgenic mouse model Journal of Neuroscience Research ·Yusuke Seino, Takeshi Kawarabayashi, Laan E., Masao Watanabe, Ayumi Takamura, Rosana Camilo da Rosa, Tomoko Kurata, Kōji Abe, Masaki Ikeda, David Westaway, Tetsuro Murakami, Peter St George‐Hyslop, Etsuro Matsubara, Mikio Shoji	2010	27
13	Frequent Missense and Insertion/Deletion Polymorphisms in the Ovine Shadoo Gene Parallel Species-Specific Variation in PrP PLoS ONE ·Nathalie Daude, Serene Wohlgemuth, Ekaterina Rogaeva, Roslyn Weissz, Michael P. Heaton, David Westaway	2009	16
14	Proteinase-Activated Receptor-2 Exerts Protective and Pathogenic Cell Type-Specific Effects in Alzheimer’s Disease The Journal of Immunology ·Jean Figarella, Farshid Noorbakhsh, Anatolii Fedorovich Maksimov, Nathalie Vergnolle, David Westaway, Jack H. Jhamandas, Patricia Andrade‐Gordon, Morley D. Hollenberg, Yuenian Shen, Richard H. Dyck, Christopher Power	2007	53
15	Genetic Control of Prion Incubation Period in Mice Novartis Foundation symposium ·George A. Carlson, David Westaway, Patricia A. Goodman, Achmad Maqsudi, Susan T. Marshall, Stanley B. Prusiner	2007	3
16	Accumulation of Filamentous Tau in the Cerebral Cortex of Human Tau R406W Transgenic Mice American Journal Of Pathology ·Masaki Ikeda, Toshitaka Kawarai, Takeshi Kawarabayashi, Etsuro Matsubara, Tetsuro Murakami, Atsushi Sasaki, Yasushi Tomidokoro, Yasushi Ikarashi, Hisashi Kuribara, Koichi Ishiguro, Masato Hasegawa, Shu‐Hui Yen, M. Azhar Chishti, Yasuo Harigaya, Kōji Abe, Koichi Okamoto, Peter St George‐Hyslop, David Westaway, Mikio Shoji	2005	88
17	Mouse models of Alzheimer's disease: The long and filamentous road Neurological Research ·Amie L. Phinney, Patrick Horne, Jing Yang, Толок Е.С., Catherine Bergeron, David Westaway	2003	35
18	Syrian hamster prion protein (PrPC) is expressed in photoreceptor cells of the adult retina Neuroscience Letters ·M. Azhar Chishti, Robert Strome, George A. Carlson, David Westaway	1997	20
19	Genetics of prion diseases and prion diversity in mice Philosophical Transactions of the Royal Society B Biological Sciences ·George A. Carlson, S. J. DeArmond, Marilyn Torchia, David Westaway, S. B. Prusiner	1994	6
20	Molecular Cloning of a Human Prion Protein cDNA DNA ·Hans A. Kretzschmar, Linda Stowring, David Westaway, Z. A. Liu, Stanley B. Prusiner, Stephen J. DeArmond Hit paper breakdown →	1986	256

About David Westaway

David Westaway is a scholar working on Neurology, Nutrition and Dietetics, Physiology, Biological Psychiatry and Molecular Biology, having authored 188 papers that have together received 16.3k indexed citations. Recurring topics across this work include Prion Diseases and Protein Misfolding (107 papers), Alzheimer's disease research and treatments (70 papers), Neurological diseases and metabolism (63 papers), Trace Elements in Health (47 papers), RNA regulation and disease (14 papers), Cholinesterase and Neurodegenerative Diseases (14 papers), Neuroinflammation and Neurodegeneration Mechanisms (13 papers) and Computational Drug Discovery Methods (12 papers). The work is most often cited by research in Neurology (6.4k citations), Nutrition and Dietetics (4.9k citations), Physiology (4.5k citations), Molecular Biology (11.7k citations) and Biological Psychiatry (291 citations). David Westaway has collaborated with scholars based in Canada, United States and United Kingdom. Frequent co-authors include Stanley B. Prusiner, George A. Carlson, Michael P. McKinley, Stephen J. DeArmond, Darlene Groth, Michael Scott, Bruno Oesch, C. Mirenda, Charles Weissmann and Marilyn Torchia. Their work appears in journals such as Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Cell, PLoS Pathogens and Molecular and Cellular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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