Brian D. Sykes

36.8k total citations · 9 hit papers
468 papers, 28.5k citations indexed

About

Brian D. Sykes is a scholar working on Molecular Biology, Spectroscopy and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Brian D. Sykes has authored 468 papers receiving a total of 28.5k indexed citations (citations by other indexed papers that have themselves been cited), including 303 papers in Molecular Biology, 111 papers in Spectroscopy and 100 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Brian D. Sykes's work include Protein Structure and Dynamics (110 papers), Cardiomyopathy and Myosin Studies (91 papers) and RNA and protein synthesis mechanisms (76 papers). Brian D. Sykes is often cited by papers focused on Protein Structure and Dynamics (110 papers), Cardiomyopathy and Myosin Studies (91 papers) and RNA and protein synthesis mechanisms (76 papers). Brian D. Sykes collaborates with scholars based in Canada, United States and United Kingdom. Brian D. Sykes's co-authors include David S. Wishart, F.M. Richards, Robert S. Hodges, Monica X. Li, Peter L. Davies, Frank D. Sönnichsen, John L. Markley, William E. Hull, Arne Holm and Stéphane M. Gagné and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Brian D. Sykes

465 papers receiving 27.4k citations

Hit Papers

1H, 13C and 15N chemical ... 1991 2026 2002 2014 1995 1992 1991 1995 1995 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. 1H, 13C and 15N chemical shift referencing in biomolecular NMR
    1995 2.0k citations David S. Wishart, H. Jane Dyson et al. Journal of Biomolecular NMR profile →
  2. The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy
    1992 1.8k citations David S. Wishart, Brian D. Sykes et al. Biochemistry profile →
  3. Relationship between nuclear magnetic resonance chemical shift and protein secondary structure
    1991 1.7k citations David S. Wishart, Brian D. Sykes et al. profile →
  4. 1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects
    1995 1.5k citations David S. Wishart, Robert S. Hodges et al. Journal of Biomolecular NMR profile →
  5. 1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects
    1995 946 citations David S. Wishart, A. Holm et al. Journal of Biomolecular NMR profile →
  6. [12] Chemical shifts as a tool for structure determination
    1994 748 citations David S. Wishart, Brian D. Sykes Methods in enzymology on CD-ROM/Methods in enzymology profile →
  7. Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide
    1992 532 citations Frank D. Sönnichsen, Robert S. Hodges et al. Biochemistry profile →
  8. Recommendations for the presentation of NMR structures of proteins and nucleic acids – IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy
    1998 398 citations Brian D. Sykes et al. Journal of Biomolecular NMR profile →
  9. Recommendations for the presentation of NMR structures of proteins and nucleic acids (IUPAC Recommendations 1998)
    1998 336 citations Brian D. Sykes et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Brian D. Sykes Canada 74 19.2k 4.6k 4.2k 3.1k 2.4k 468 28.5k
Robert S. Hodges Canada 84 19.0k 1.0× 4.1k 0.9× 2.2k 0.5× 1.8k 0.6× 1.3k 0.6× 392 25.6k
Mitsuhiko Ikura Canada 86 22.1k 1.1× 3.2k 0.7× 4.0k 0.9× 1.2k 0.4× 836 0.4× 305 29.8k
William F. DeGrado United States 111 32.1k 1.7× 4.5k 1.0× 6.7k 1.6× 734 0.2× 1.3k 0.6× 538 43.5k
Gregory S. Couch United States 8 28.6k 1.5× 1.2k 0.3× 4.3k 1.0× 1.4k 0.4× 2.8k 1.2× 11 44.5k
Stephan Grzesiek Switzerland 66 22.5k 1.2× 6.0k 1.3× 6.0k 1.4× 626 0.2× 838 0.4× 171 29.5k
Elaine C. Meng United States 29 32.3k 1.7× 1.4k 0.3× 4.9k 1.2× 1.5k 0.5× 3.0k 1.3× 35 50.0k
Richard A. Lerner United States 95 22.2k 1.2× 1.7k 0.4× 1.9k 0.5× 973 0.3× 1.6k 0.7× 417 38.4k
Brian T. Chait United States 112 36.6k 1.9× 12.7k 2.8× 2.7k 0.6× 3.7k 1.2× 1.1k 0.4× 434 55.5k
Conrad C. Huang United States 31 31.3k 1.6× 1.4k 0.3× 4.9k 1.2× 1.5k 0.5× 3.0k 1.3× 48 49.3k
Alexander Rich United States 110 36.0k 1.9× 2.1k 0.5× 2.9k 0.7× 974 0.3× 3.6k 1.5× 450 43.6k

Countries citing papers authored by Brian D. Sykes

Since Specialization
Citations

This map shows the geographic impact of Brian D. Sykes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian D. Sykes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian D. Sykes more than expected).

Fields of papers citing papers by Brian D. Sykes

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian D. Sykes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian D. Sykes. The network helps show where Brian D. Sykes may publish in the future.

Co-authorship network of co-authors of Brian D. Sykes

This figure shows the co-authorship network connecting the top 25 collaborators of Brian D. Sykes. A scholar is included among the top collaborators of Brian D. Sykes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian D. Sykes. Brian D. Sykes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kampourakis, Thomas, et al.. (2023). Conversion of a Cardiac Muscle Modulator from an Inhibitor to an Activator. ACS Medicinal Chemistry Letters. 14(4). 530–533. 2 indexed citations
2.
Kampourakis, Thomas, et al.. (2022). Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7. ACS Chemical Biology. 17(6). 1495–1504. 1 indexed citations
3.
Kampourakis, Thomas, et al.. (2021). A Potent Fluorescent Reversible-Covalent Inhibitor of Cardiac Muscle Contraction. ACS Medicinal Chemistry Letters. 12(9). 1503–1507. 1 indexed citations
4.
Robertson, Ian M., et al.. (2020). The Role of Electrostatics in the Mechanism of Cardiac Thin Filament Based Sensitizers. ACS Chemical Biology. 15(8). 2289–2298. 5 indexed citations
5.
Daude, Nathalie, Charles E. Mays, Serene Wohlgemuth, et al.. (2018). A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles. PLoS Pathogens. 14(1). e1006826–e1006826. 17 indexed citations
6.
Robertson, Ian M., et al.. (2015). The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q. Journal of Molecular and Cellular Cardiology. 87. 257–269. 16 indexed citations
7.
Robertson, Ian M., et al.. (2014). In Vitro and in Situ Structure and Function of the Cardiac Troponin C Familial Hypertrophic Cardiomyopathy-Linked Mutation, L29Q. Biophysical Journal. 106(2). 723a–724a. 1 indexed citations
8.
Szeto, Samuel S.W., Stacey N. Reinke, Kayode S. Oyedotun, Brian D. Sykes, & Bernard D. Lemire. (2012). Expression of Saccharomyces cerevisiae Sdh3p and Sdh4p Paralogs Results in Catalytically Active Succinate Dehydrogenase Isoenzymes. Journal of Biological Chemistry. 287(27). 22509–22520. 12 indexed citations
9.
Robertson, Ian M., Monica X. Li, & Brian D. Sykes. (2009). Solution Structure of Human Cardiac Troponin C in Complex with the Green Tea Polyphenol, (−)-Epigallocatechin 3-Gallate. Journal of Biological Chemistry. 284(34). 23012–23023. 52 indexed citations
10.
Saude, Erik J., Ray Somorjai, Brion Dolenko, et al.. (2008). Metabolomic Biomarkers in a Model of Asthma Exacerbation. American Journal of Respiratory and Critical Care Medicine. 179(1). 25–34. 54 indexed citations
11.
Gillis, Todd E., Tharin M. A. Blumenschein, Brian D. Sykes, & Glen F. Tibbits. (2002). Site I binds Ca2+ in trout cardiac troponin C. Biophysical Journal. 82(1). 1 indexed citations
12.
Saude, Erik J., et al.. (2002). Kinetic studies of calcium and cardiac troponin I peptide binding to human cardiac troponin C using NMR spectroscopy. European Biophysics Journal. 31(4). 245–256. 39 indexed citations
13.
Sykes, Brian D.. (1999). The Human inheritance : genes, language, and evolution. DigitalGeorgetown (Georgetown University Library). 10 indexed citations
14.
Houston, Michael E., Heman Chao, Robert S. Hodges, et al.. (1998). Binding of an Oligopeptide to a Specific Plane of Ice. Journal of Biological Chemistry. 273(19). 11714–11718. 66 indexed citations
15.
Rajarathnam, Krishnakumar, Cyril M. Kay, Ian Clark‐Lewis, & Brian D. Sykes. (1997). Characterization of quaternary structure of interleukin-8 and functional implications. Methods in enzymology on CD-ROM/Methods in enzymology. 287. 89–105. 24 indexed citations
16.
Sia, Samuel K., Monica X. Li, Leo Spyracopoulos, et al.. (1997). Structure of Cardiac Muscle Troponin C Unexpectedly Reveals a Closed Regulatory Domain. Journal of Biological Chemistry. 272(29). 18216–18221. 165 indexed citations
17.
Campbell, A. Patricia, Brian D. Sykes, Erling Norrby, Nuria Assa‐Munt, & H. Jane Dyson. (1996). Solution conformation of an immunogenic peptide derived from the principal neutralizing determinant of the HIV-2 envelope glycoprotein gp125. PubMed. 1(2). 157–165. 8 indexed citations
18.
Wishart, David S., et al.. (1995). 1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects. Journal of Biomolecular NMR. 5(3). 332–332. 946 indexed citations breakdown →
19.
20.
Sanders, Clive, Brian D. Sykes, & Lawrence B. Smillie. (1988). Comparison of the structure and dynamics of chicken gizzard and rabbit cardiac tropomyosins: proton NMR spectroscopy and measurement of amide hydrogen exchange rates. Biochemistry. 27(18). 7000–7008. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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