Yihai Cao

40.2k total citations · 17 hit papers
274 papers, 28.5k citations indexed

About

Yihai Cao is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Yihai Cao has authored 274 papers receiving a total of 28.5k indexed citations (citations by other indexed papers that have themselves been cited), including 184 papers in Molecular Biology, 89 papers in Cancer Research and 60 papers in Oncology. Recurrent topics in Yihai Cao's work include Angiogenesis and VEGF in Cancer (119 papers), Cancer, Hypoxia, and Metabolism (65 papers) and Lymphatic System and Diseases (29 papers). Yihai Cao is often cited by papers focused on Angiogenesis and VEGF in Cancer (119 papers), Cancer, Hypoxia, and Metabolism (65 papers) and Lymphatic System and Diseases (29 papers). Yihai Cao collaborates with scholars based in Sweden, China and United States. Yihai Cao's co-authors include Renhai Cao, Ebba Bråkenhielm, Takahiro Seki, Yunlong Yang, Sharon Lim, Kari Alitalo, Kayoko Hosaka, Henrich Cheng, Róbert Langer and Lasse D. Jensen and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Yihai Cao

269 papers receiving 28.0k citations

Hit Papers

Monitoring Drug Target Engagement i... 1996 2026 2006 2016 2013 2018 2000 1997 1996 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
    2013 1.5k citations Daniel Martinez Molina, Rozbeh Jafari et al. Science profile →
  2. Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy
    2018 730 citations Yihai Cao et al. Proceedings of the National Academy of Sciences profile →
  3. Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I
    2000 653 citations Zhongjun Zhou, Renhai Cao et al. Proceedings of the National Academy of Sciences profile →
  4. Proteolytic processing regulates receptor specificity and activity of VEGF-C
    1997 628 citations Yihai Cao et al. profile →
  5. Spinal Cord Repair in Adult Paraplegic Rats: Partial Restoration of Hind Limb Function
    1996 615 citations Yihai Cao et al. Science profile →
  6. Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis
    2004 593 citations Ebba Bråkenhielm, Renhai Cao et al. Proceedings of the National Academy of Sciences profile →
  7. Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2
    2003 590 citations Renhai Cao, Ebba Bråkenhielm et al. profile →
  8. Angiogenesis modulates adipogenesis and obesity
    2007 568 citations Yihai Cao profile →
  9. Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression
    2001 524 citations Renhai Cao, Yihai Cao et al. profile →
  10. Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
    2021 370 citations Wei Chen, Yihai Cao et al. Nature Reviews Cardiology profile →
  11. Adipocyte and lipid metabolism in cancer drug resistance
    2019 356 citations Yihai Cao profile →
  12. The landscape of mRNA nanomedicine
    2022 339 citations Xiangang Huang, Na Kong et al. profile →
  13. In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment
    2020 308 citations Zhongmin Tang, Na Kong et al. Proceedings of the National Academy of Sciences profile →
  14. The impact of VEGF on cancer metastasis and systemic disease
    2022 183 citations Yunlong Yang, Yihai Cao profile →
  15. Targeting angiogenesis in oncology, ophthalmology and beyond
    2023 173 citations Yihai Cao et al. profile →
  16. Brown-fat-mediated tumour suppression by cold-altered global metabolism
    2022 148 citations Takahiro Seki, Yunlong Yang et al. profile →
  17. Intravesical delivery of KDM6A -mRNA via mucoadhesive nanoparticles inhibits the metastasis of bladder cancer
    2022 128 citations Na Kong, Gongwei Wu et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Yihai Cao Sweden 93 15.7k 6.9k 6.5k 3.3k 2.9k 274 28.5k
Gou Young Koh South Korea 86 16.6k 1.1× 4.8k 0.7× 3.5k 0.5× 4.7k 1.4× 3.2k 1.1× 274 29.2k
Hong Wu United States 89 16.6k 1.1× 7.2k 1.0× 4.5k 0.7× 2.0k 0.6× 3.1k 1.1× 204 26.2k
Doménico Ribatti Italy 93 17.8k 1.1× 8.6k 1.3× 5.8k 0.9× 2.2k 0.7× 7.1k 2.5× 872 35.3k
Gerry Melino Italy 97 22.1k 1.4× 11.0k 1.6× 7.1k 1.1× 2.7k 0.8× 3.5k 1.2× 625 36.9k
Michael Detmar Switzerland 88 14.6k 0.9× 14.0k 2.0× 4.3k 0.7× 3.2k 1.0× 4.3k 1.5× 292 31.7k
Chu‐Xia Deng United States 119 31.1k 2.0× 9.0k 1.3× 5.5k 0.8× 5.3k 1.6× 2.7k 1.0× 414 47.2k
Shahin Rafii United States 99 21.4k 1.4× 10.8k 1.6× 6.9k 1.1× 1.7k 0.5× 6.1k 2.1× 304 39.1k
Jian Wang China 79 14.5k 0.9× 5.6k 0.8× 6.6k 1.0× 1.2k 0.4× 4.4k 1.6× 1.1k 28.6k
Lena Claesson‐Welsh Sweden 87 22.2k 1.4× 6.9k 1.0× 5.8k 0.9× 1.7k 0.5× 3.5k 1.2× 256 32.3k
Murray Korc United States 89 14.7k 0.9× 12.3k 1.8× 5.5k 0.8× 1.4k 0.4× 2.5k 0.9× 370 26.5k

Countries citing papers authored by Yihai Cao

Since Specialization
Citations

This map shows the geographic impact of Yihai Cao's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yihai Cao with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yihai Cao more than expected).

Fields of papers citing papers by Yihai Cao

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yihai Cao. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yihai Cao. The network helps show where Yihai Cao may publish in the future.

Co-authorship network of co-authors of Yihai Cao

This figure shows the co-authorship network connecting the top 25 collaborators of Yihai Cao. A scholar is included among the top collaborators of Yihai Cao based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yihai Cao. Yihai Cao is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Zhou, Zhuoming, Wei Chen, Yihai Cao, Reza Abdi, & Wei Tao. (2024). Nanomedicine-based strategies for the treatment of vein graft disease. Nature Reviews Cardiology. 22(4). 255–272. 3 indexed citations
2.
Sun, Xiaoting, Wenhai Sui, Zepeng Mu, et al.. (2023). Mirabegron displays anticancer effects by globally browning adipose tissues. Nature Communications. 14(1). 7610–7610. 15 indexed citations
3.
Liu, Haijun, Wei Chen, Gongwei Wu, et al.. (2023). Glutathione‐Scavenging Nanoparticle‐Mediated PROTACs Delivery for Targeted Protein Degradation and Amplified Antitumor Effects. Advanced Science. 10(16). e2207439–e2207439. 57 indexed citations
4.
Thijssen, Victor L., Patrycja Nowak‐Sliwinska, Katrin Deumelandt, et al.. (2018). Targeting PDGF‐mediated recruitment of pericytes blocks vascular mimicry and tumor growth. The Journal of Pathology. 246(4). 447–458. 75 indexed citations
5.
Zhang, Yunjian, Sharon Lim, Kayoko Hosaka, et al.. (2017). A Zebrafish Model Discovers a Novel Mechanism of Stromal Fibroblast-Mediated Cancer Metastasis. Clinical Cancer Research. 23(16). 4769–4779. 66 indexed citations
6.
Jia, Min, Trygve Andreassen, Lasse D. Jensen, et al.. (2016). Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism. Cancer Research. 76(19). 5634–5646. 49 indexed citations
7.
Svensson, Susanne, Annelie Abrahamsson, Gabriela Vazquez Rodriguez, et al.. (2015). CCL2 and CCL5 Are Novel Therapeutic Targets for Estrogen-Dependent Breast Cancer. Clinical Cancer Research. 21(16). 3794–3805. 178 indexed citations
8.
Cao, Renhai, Hong Ji, Yunlong Yang, & Yihai Cao. (2015). Collaborative effects between the TNFα-TNFR1-macrophage axis and the VEGF-C-VEGFR3 signaling in lymphangiogenesis and metastasis. OncoImmunology. 4(3). e989777–e989777. 10 indexed citations
9.
Zheng, Xiaowei, Alex‐Xianghua Zhou, Pegah Rouhi, et al.. (2014). Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response. Proceedings of the National Academy of Sciences. 111(7). 2560–2565. 63 indexed citations
10.
Zhao, Chunyan, Yichun Qiao, Philip Jonsson, et al.. (2014). Genome-wide Profiling of AP-1–Regulated Transcription Provides Insights into the Invasiveness of Triple-Negative Breast Cancer. Cancer Research. 74(14). 3983–3994. 104 indexed citations
11.
Wang, Jian, Ziquan Cao, Xing‐Mei Zhang, et al.. (2014). Novel Mechanism of Macrophage-Mediated Metastasis Revealed in a Zebrafish Model of Tumor Development. Cancer Research. 75(2). 306–315. 113 indexed citations
12.
Honek, Jennifer, Sharon Lim, Carina Fischer, et al.. (2014). Brown adipose tissue, thermogenesis, angiogenesis: pathophysiological aspects. Hormone Molecular Biology and Clinical Investigation. 19(1). 5–11. 15 indexed citations
13.
Molina, Daniel Martinez, Rozbeh Jafari, Marina Ignatushchenko, et al.. (2013). Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay. Science. 341(6141). 84–87. 1510 indexed citations breakdown →
14.
Tang, Zhongshu, Pachiappan Arjunan, Chunsik Lee, et al.. (2010). Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3β phosphorylation. The Journal of Experimental Medicine. 207(4). 867–880. 94 indexed citations
15.
Xue, Yuan, Piotr Religa, Renhai Cao, et al.. (2008). Anti-VEGF agents confer survival advantages to tumor-bearing mice by improving cancer-associated systemic syndrome. Proceedings of the National Academy of Sciences. 105(47). 18513–18518. 57 indexed citations
16.
Clasper, Steven, Daniel Royston, Dilair Baban, et al.. (2008). A Novel Gene Expression Profile in Lymphatics Associated with Tumor Growth and Nodal Metastasis. Cancer Research. 68(18). 7293–7303. 90 indexed citations
17.
Cao, Yihai. (2008). Why and How Do Tumors Stimulate Lymphangiogenesis?. Lymphatic Research and Biology. 6(3-4). 145–148. 19 indexed citations
18.
Religa, Piotr, Renhai Cao, Meit A. Björndahl, et al.. (2005). Presence of bone marrow–derived circulating progenitor endothelial cells in the newly formed lymphatic vessels. Blood. 106(13). 4184–4190. 108 indexed citations
19.
Björndahl, Meit A., Renhai Cao, Jeremy B. Burton, et al.. (2005). Vascular Endothelial Growth Factor-A Promotes Peritumoral Lymphangiogenesis and Lymphatic Metastasis. Cancer Research. 65(20). 9261–9268. 152 indexed citations
20.
Zhou, Zhongjun, Masayuki Doi, Jianming Wang, et al.. (2004). Deletion of Laminin-8 Results in Increased Tumor Neovascularization and Metastasis in Mice. Cancer Research. 64(12). 4059–4063. 31 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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