Paul E. Fraser

19.1k total citations · 3 hit papers
153 papers, 13.7k citations indexed

About

Paul E. Fraser is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Paul E. Fraser has authored 153 papers receiving a total of 13.7k indexed citations (citations by other indexed papers that have themselves been cited), including 100 papers in Physiology, 92 papers in Molecular Biology and 22 papers in Cellular and Molecular Neuroscience. Recurrent topics in Paul E. Fraser's work include Alzheimer's disease research and treatments (96 papers), Prion Diseases and Protein Misfolding (24 papers) and Protein Structure and Dynamics (20 papers). Paul E. Fraser is often cited by papers focused on Alzheimer's disease research and treatments (96 papers), Prion Diseases and Protein Misfolding (24 papers) and Protein Structure and Dynamics (20 papers). Paul E. Fraser collaborates with scholars based in Canada, United States and United Kingdom. Paul E. Fraser's co-authors include Louise C. Serpell, Margaret Sunde, Mark B. Pepys, Colin Blake, JoAnne McLaurin, Daniel A. Kirschner, Mark Bartlam, Véronique Dorval, Avijit Chakrabartty and Jack Nguyen and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Paul E. Fraser

153 papers receiving 13.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Common core structure of amyloid fibrils by synchrotron X-ray diffraction 1 1Edited by F. E. Cohen

1997 1.4k citations Margaret Sunde, Louise C. Serpell et al. profile →
The cellular prion protein binds copper in vivo

1997 1.0k citations Paul E. Fraser et al. Nature profile →
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

1997 891 citations David R. Booth, Margaret Sunde et al. Nature profile →

Peers

Countries citing papers authored by Paul E. Fraser

Since Specialization

Citations

This map shows the geographic impact of Paul E. Fraser's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul E. Fraser with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul E. Fraser more than expected).

Fields of papers citing papers by Paul E. Fraser

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul E. Fraser. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul E. Fraser. The network helps show where Paul E. Fraser may publish in the future.

Co-authorship network of co-authors of Paul E. Fraser

This figure shows the co-authorship network connecting the top 25 collaborators of Paul E. Fraser. A scholar is included among the top collaborators of Paul E. Fraser based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul E. Fraser. Paul E. Fraser is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Brain microenvironment-remodeling nanomedicine improves cerebral glucose metabolism, mitochondrial activity and synaptic function in a mouse model of Alzheimer's disease 2025 ·Biomaterials ·(unknown), Chunsheng He, Azhar Z. Abbasi, Meng Tian, (unknown), Li‐Ting Wang, John Georgiou, Graham L. Collingridge, Paul E. Fraser, Jeffrey T. Henderson, Xiao Yu Wu	6
2	SARS-CoV-2 Nucleocapsid Protein Induces Tau Pathological Changes That Can Be Counteracted by SUMO2 2024 ·International Journal of Molecular Sciences ·Franca Orsini, (unknown), (unknown), Massimiliano De Paola, (unknown), Rosaria Pascente, Gianluigi Forloni, Paul E. Fraser, Ottavio Arancio, Luana Fioriti	3
3	Brain‐Penetrating and Disease Site‐Targeting Manganese Dioxide‐Polymer‐Lipid Hybrid Nanoparticles Remodel Microenvironment of Alzheimer's Disease by Regulating Multiple Pathological Pathways 2023 ·Advanced Science ·(unknown), (unknown), Chunsheng He, Azhar Z. Abbasi, Taksim Ahmed, Warren D. Foltz, R. Michael O'Flaherty, (unknown), Robert P. Bonin, Andrew M. Rauth, Paul E. Fraser, Jeffrey T. Henderson, Xiao Yu Wu	28
4	Differential interaction with TREM2 modulates microglial uptake of modified Aβ species 2021 ·Glia ·Pranav Joshi, (unknown), (unknown), Masahiro Enomoto, Seema Qamar, Hannah Scheiblich, (unknown), Sathish Kumar, (unknown), Samira Parhizkar, Christian Haass, Michael T. Heneka, Paul E. Fraser, Peter St George‐Hyslop, Jochen Walter	12
5	Pancreatic β cell–selective zinc transporter 8 insufficiency accelerates diabetes associated with islet amyloidosis 2021 ·JCI Insight ·Jie Xu, Nadeeja Wijesekara, (unknown), Dana Al Rijjal, (unknown), (unknown), Anne Wu, Alpana Bhattacharjee, Ying Liu, Lucy Marzban, Jonathan V. Rocheleau, Paul E. Fraser, Feihan F. Dai, Cheng Hu, Michael B. Wheeler	19
6	Tau is not necessary for amyloid-β–induced synaptic and memory impairments 2020 ·Journal of Clinical Investigation ·Daniela Puzzo, Elentina K. Argyrousi, Agnieszka Staniszewski, Hong Zhang, Elisa Calcagno, (unknown), Erica Acquarone, Mauro Fà, Domenica Donatella Li Puma, Claudio Grassi, Luciano D'adamio, Nicholas M. Kanaan, Paul E. Fraser, Ottavio Arancio	36
7	Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau 2018 ·Molecular Psychiatry ·Mickaël Audrain, Jean‐Vianney Haure‐Mirande, Minghui Wang, Soong Ho Kim, Tomas Fanutza, Paramita Chakrabarty, Paul E. Fraser, Peter St George‐Hyslop, Todd E. Golde, Robert D. Blitzer, Eric E. Schadt, Bin Zhang, Michelle E. Ehrlich, Sam Gandy	52
8	LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent 2017 ·eLife ·Daniela Puzzo, Roberto Piacentini, Mauro Fà, Walter Gulisano, Domenica Donatella Li Puma, Agnes Staniszewski, Hong Zhang, Maria Rosaria Tropea, Sara Cocco, Agostino Palmeri, Paul E. Fraser, Luciano D'adamio, Claudio Grassi, Ottavio Arancio	127
9	SUMO1 impact on Alzheimer disease pathology in an amyloid-depositing mouse model 2017 ·Neurobiology of Disease ·Erin Knock, Shinsuke Matsuzaki, Hironori Takamura, (unknown), (unknown), Kyung Ho Han, Hong Zhang, Agnieszka Staniszewski, Taiichi Katayama, Ottavio Arancio, Paul E. Fraser	28
10	SUMO1 Affects Synaptic Function, Spine Density and Memory 2015 ·Scientific Reports ·Shinsuke Matsuzaki, Linda Lee, Erin Knock, Tharan Srikumar, Mikako Sakurai, Lili‐Naz Hazrati, Taiichi Katayama, Agnieszka Staniszewski, Brian Raught, Ottavio Arancio, Paul E. Fraser	55
11	Amyloid Formation in Human Islets Is Enhanced by Heparin and Inhibited by Heparinase 2015 ·American Journal of Transplantation ·Kathryn J. Potter, (unknown), Heather C. Denroche, Joel Montané, Annette Plesner, (unknown), (unknown), Galina Soukhatcheva, Garth L. Warnock, José Oberholzer, Paul E. Fraser, C. Bruce Verchere	28
12	Altered brain development in an early-onset murine model of Alzheimer's disease 2014 ·Neurobiology of Aging ·(unknown), Jan Scholz, Jacob Ellegood, Lindsay S. Cahill, Christine Laliberté, Paul E. Fraser, Sheena A. Josselyn, John G. Sled, Jason P. Lerch	14
13	The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin 2011 ·Cell stem cell ·Simon R. Smukler, (unknown), Rozita Razavi, George Bikopoulos, Phillip Karpowicz, Raewyn M. Seaberg, Feihan F. Dai, Simon Lee, Rosemary Ahrens, Paul E. Fraser, Michael B. Wheeler, Derek van der Kooy	168
14	Proteoglycans and Amyloid Fibrillogenesis 2007 ·Novartis Foundation symposium ·Robert Kisilevsky, Paul E. Fraser	5
15	[34] X-Ray fiber diffraction of amyloid fibrils 1999 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Louise C. Serpell, Paul E. Fraser, Margaret Sunde	105
16	New clothes for amyloid enhancing factor (AEF): Silk as AEF 1999 ·Amyloid ·Robert Kisilevsky, (unknown), (unknown), (unknown), Paul E. Fraser	45
17	A sulfated proteoglycan aggregation factor mediates amyloid-β peptide fibril formation and neurotoxicity 1999 ·Amyloid ·JoAnne McLaurin, (unknown), William J. Kuhns, Paul E. Fraser	30
18	Developmental Expression of Wild-Type and Mutant Presenilin-1 in Hippocampal Neurons from Transgenic Mice: Evidence for Novel Species-Specific Properties of Human Presenilin-1 1999 ·Molecular Medicine ·Lyne Lévesque, Willem Annaert, Katleen Craessaerts, Paul M. Mathews, Mary Seeger, Ralph A. Nixon, (unknown), Sam Gandy, David Westaway, Peter St George‐Hyslop, Bart De Strooper, Paul E. Fraser	27
19	Structural Transitions Associated with the Interaction of Alzheimer β-Amyloid Peptides with Gangliosides 1998 ·Journal of Biological Chemistry ·JoAnne McLaurin, (unknown), Paul E. Fraser, Avijit Chakrabartty	152
20	Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis breakdown → 1997 ·Nature ·David R. Booth, Margaret Sunde, Vittorio Bellotti, Carol V. Robinson, Winston L. Hutchinson, Paul E. Fraser, Philip N. Hawkins, Christopher M. Dobson, Sheena E. Radford, Colin Blake, Mark B. Pepys	891

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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