Paul E. Fraser

19.1k total citations · 3 hit papers
153 papers, 13.7k citations indexed

About

Paul E. Fraser is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Paul E. Fraser has authored 153 papers receiving a total of 13.7k indexed citations (citations by other indexed papers that have themselves been cited), including 100 papers in Physiology, 92 papers in Molecular Biology and 22 papers in Cellular and Molecular Neuroscience. Recurrent topics in Paul E. Fraser's work include Alzheimer's disease research and treatments (96 papers), Prion Diseases and Protein Misfolding (24 papers) and Protein Structure and Dynamics (20 papers). Paul E. Fraser is often cited by papers focused on Alzheimer's disease research and treatments (96 papers), Prion Diseases and Protein Misfolding (24 papers) and Protein Structure and Dynamics (20 papers). Paul E. Fraser collaborates with scholars based in Canada, United States and United Kingdom. Paul E. Fraser's co-authors include Louise C. Serpell, Margaret Sunde, Mark B. Pepys, Colin Blake, JoAnne McLaurin, Daniel A. Kirschner, Mark Bartlam, Véronique Dorval, Avijit Chakrabartty and Jack Nguyen and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Paul E. Fraser

153 papers receiving 13.5k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Common core structure of amyloid fibrils by synchrotron X-ray diffraction 1 1Edited by F. E. Cohen

1997 1.4k citations Margaret Sunde, Louise C. Serpell et al. profile →
The cellular prion protein binds copper in vivo

1997 1.0k citations Paul E. Fraser et al. profile →
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

1997 891 citations Margaret Sunde, Paul E. Fraser et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Paul E. Fraser	8.6k	7.4k	1.7k	1.6k	1.5k	153	13.7k
Mario Salmona	9.6k 1.1×	4.7k 0.6×	2.5k 1.5×	2.0k 1.3×	956 0.7×	437	17.1k
Hironobu Naiki	8.2k 1.0×	8.1k 1.1×	769 0.5×	992 0.6×	805 0.6×	217	13.8k
Massimo Stefani	9.9k 1.1×	6.5k 0.9×	718 0.4×	767 0.5×	1.5k 1.1×	183	14.5k
David Schubert	11.0k 1.3×	6.8k 0.9×	1.4k 0.8×	767 0.5×	2.1k 1.4×	196	20.4k
Daniel A. Kirschner	6.6k 0.8×	5.5k 0.8×	1.1k 0.6×	496 0.3×	1.1k 0.7×	158	11.2k
Roberto Cappai	6.9k 0.8×	9.1k 1.2×	1.7k 1.0×	3.6k 2.2×	1.1k 0.7×	235	15.9k
Robert D. Moir	8.9k 1.0×	10.2k 1.4×	1.7k 1.0×	3.2k 2.0×	2.1k 1.4×	121	19.6k
Claudio Soto	13.4k 1.6×	8.4k 1.1×	4.4k 2.6×	2.8k 1.7×	1.8k 1.3×	239	21.5k
Louise C. Serpell	11.0k 1.3×	8.4k 1.1×	1.2k 0.7×	726 0.5×	1.1k 0.7×	174	17.2k
Jorge Ghiso	8.5k 1.0×	11.8k 1.6×	2.8k 1.7×	943 0.6×	1.2k 0.8×	213	17.3k

Countries citing papers authored by Paul E. Fraser

Since Specialization

Citations

This map shows the geographic impact of Paul E. Fraser's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul E. Fraser with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul E. Fraser more than expected).

Fields of papers citing papers by Paul E. Fraser

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul E. Fraser. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul E. Fraser. The network helps show where Paul E. Fraser may publish in the future.

Co-authorship network of co-authors of Paul E. Fraser

This figure shows the co-authorship network connecting the top 25 collaborators of Paul E. Fraser. A scholar is included among the top collaborators of Paul E. Fraser based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul E. Fraser. Paul E. Fraser is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Fioriti, Luana, Nadeeja Wijesekara, Elentina K. Argyrousi, et al.. (2025). Genetic and pharmacologic enhancement of SUMO2 conjugation prevents and reverses cognitive impairment and synaptotoxicity in a preclinical model of Alzheimer's disease. Alzheimer s & Dementia. 21(3). e70030–e70030. 2 indexed citations

He, Chunsheng, Azhar Z. Abbasi, Meng Tian, et al.. (2025). Brain microenvironment-remodeling nanomedicine improves cerebral glucose metabolism, mitochondrial activity and synaptic function in a mouse model of Alzheimer's disease. Biomaterials. 318. 123142–123142. 6 indexed citations

Orsini, Franca, Massimiliano De Paola, Rosaria Pascente, et al.. (2024). SARS-CoV-2 Nucleocapsid Protein Induces Tau Pathological Changes That Can Be Counteracted by SUMO2. International Journal of Molecular Sciences. 25(13). 7169–7169. 3 indexed citations

Carlessi, Rodrigo, Miheer Sabale, Janina E. E. Tirnitz‐Parker, et al.. (2023). Quantitative comparison of presenilin protein expression reveals greater activity of PS2‐γ‐secretase. The FASEB Journal. 38(1). e23396–e23396. 2 indexed citations

He, Chunsheng, Azhar Z. Abbasi, Taksim Ahmed, et al.. (2023). Brain‐Penetrating and Disease Site‐Targeting Manganese Dioxide‐Polymer‐Lipid Hybrid Nanoparticles Remodel Microenvironment of Alzheimer's Disease by Regulating Multiple Pathological Pathways. Advanced Science. 10(12). e2207238–e2207238. 28 indexed citations

Joshi, Pranav, Masahiro Enomoto, Seema Qamar, et al.. (2021). Differential interaction with TREM2 modulates microglial uptake of modified Aβ species. Glia. 69(12). 2917–2932. 12 indexed citations

Xu, Jie, Nadeeja Wijesekara, Dana Al Rijjal, et al.. (2021). Pancreatic β cell–selective zinc transporter 8 insufficiency accelerates diabetes associated with islet amyloidosis. JCI Insight. 6(10). 19 indexed citations

Puzzo, Daniela, Elentina K. Argyrousi, Agnieszka Staniszewski, et al.. (2020). Tau is not necessary for amyloid-β–induced synaptic and memory impairments. Journal of Clinical Investigation. 130(9). 4831–4844. 36 indexed citations

Audrain, Mickaël, Jean‐Vianney Haure‐Mirande, Justyna Mleczko, et al.. (2020). Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice. Alzheimer s & Dementia. 17(2). 149–163. 36 indexed citations

10.

Puzzo, Daniela, Roberto Piacentini, Mauro Fà, et al.. (2017). LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent. eLife. 6. 127 indexed citations

11.

Knock, Erin, Shinsuke Matsuzaki, Hironori Takamura, et al.. (2017). SUMO1 impact on Alzheimer disease pathology in an amyloid-depositing mouse model. Neurobiology of Disease. 110. 154–165. 28 indexed citations

12.

Matsuzaki, Shinsuke, Linda Lee, Erin Knock, et al.. (2015). SUMO1 Affects Synaptic Function, Spine Density and Memory. Scientific Reports. 5(1). 55 indexed citations

13.

Potter, Kathryn J., Heather C. Denroche, Joel Montané, et al.. (2015). Amyloid Formation in Human Islets Is Enhanced by Heparin and Inhibited by Heparinase. American Journal of Transplantation. 15(6). 1519–1530. 28 indexed citations

14.

Scholz, Jan, Jacob Ellegood, Lindsay S. Cahill, et al.. (2014). Altered brain development in an early-onset murine model of Alzheimer's disease. Neurobiology of Aging. 36(2). 638–647. 14 indexed citations

15.

Kisilevsky, Robert & Paul E. Fraser. (2007). Proteoglycans and Amyloid Fibrillogenesis. Novartis Foundation symposium. 199. 58–72. 5 indexed citations

16.

Fraser, Paul E., Audrey A. Darabie, & JoAnne McLaurin. (2001). Amyloid-β Interactions with Chondroitin Sulfate-derived Monosaccharides and Disaccharides. Journal of Biological Chemistry. 276(9). 6412–6419. 63 indexed citations

17.

Serpell, Louise C., Paul E. Fraser, & Margaret Sunde. (1999). [34] X-Ray fiber diffraction of amyloid fibrils. Methods in enzymology on CD-ROM/Methods in enzymology. 309. 526–536. 105 indexed citations

18.

Kisilevsky, Robert, et al.. (1999). New clothes for amyloid enhancing factor (AEF): Silk as AEF. Amyloid. 6(2). 98–106. 45 indexed citations

19.

Lévesque, Lyne, Willem Annaert, Katleen Craessaerts, et al.. (1999). Developmental Expression of Wild-Type and Mutant Presenilin-1 in Hippocampal Neurons from Transgenic Mice: Evidence for Novel Species-Specific Properties of Human Presenilin-1. Molecular Medicine. 5(8). 542–554. 27 indexed citations

20.

Kisilevsky, Robert, Laura J. Lemieux, Paul E. Fraser, et al.. (1995). Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease. Nature Medicine. 1(2). 143–148. 280 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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