Claudio Soto

30.3k total citations · 9 hit papers
239 papers, 21.5k citations indexed

About

Claudio Soto is a scholar working on Molecular Biology, Physiology and Neurology. According to data from OpenAlex, Claudio Soto has authored 239 papers receiving a total of 21.5k indexed citations (citations by other indexed papers that have themselves been cited), including 168 papers in Molecular Biology, 100 papers in Physiology and 64 papers in Neurology. Recurrent topics in Claudio Soto's work include Prion Diseases and Protein Misfolding (127 papers), Alzheimer's disease research and treatments (99 papers) and Neurological diseases and metabolism (57 papers). Claudio Soto is often cited by papers focused on Prion Diseases and Protein Misfolding (127 papers), Alzheimer's disease research and treatments (99 papers) and Neurological diseases and metabolism (57 papers). Claudio Soto collaborates with scholars based in United States, Chile and Spain. Claudio Soto's co-authors include Joaquı́n Castilla, Sandra Pritzkow, Paula Saá, Rodrigo Morales, Gabriela P. Saborı́o, Blas Frangione, Lisbell D. Estrada, Bruno Permanne, Claudio Hetz and Inés Moreno‐González and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Claudio Soto

237 papers receiving 20.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Unfolding the role of protein misfolding in neurodegenerative diseases

2003 1.2k citations Claudio Soto profile →
Acetylcholinesterase Accelerates Assembly of Amyloid-β-Peptides into Alzheimer's Fibrils: Possible Role of the Peripheral Site of the Enzyme

1996 965 citations Claudio Soto et al. profile →
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding

2001 961 citations Claudio Soto et al. profile →
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases

2018 798 citations Claudio Soto, Sandra Pritzkow profile →
β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy

1998 742 citations Claudio Soto et al. Nature Medicine profile →
In Vitro Generation of Infectious Scrapie Prions

2005 611 citations Joaquı́n Castilla, Paula Saá et al. Cell profile →
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy

2020 535 citations Abhisek Mukherjee, Sandra Pritzkow et al. profile →
Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid

2016 348 citations Claudia Trenkwalder, Brit Mollenhauer et al. profile →
Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid

2023 113 citations Sandra Pritzkow, Claudio Soto et al. profile →

Peers

Countries citing papers authored by Claudio Soto

Since Specialization

Citations

This map shows the geographic impact of Claudio Soto's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Claudio Soto with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Claudio Soto more than expected).

Fields of papers citing papers by Claudio Soto

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Claudio Soto. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Claudio Soto. The network helps show where Claudio Soto may publish in the future.

Co-authorship network of co-authors of Claudio Soto

This figure shows the co-authorship network connecting the top 25 collaborators of Claudio Soto. A scholar is included among the top collaborators of Claudio Soto based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Claudio Soto. Claudio Soto is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Toward a biological definition of neuronal and glial synucleinopathies 2025 ·Nature Medicine ·Claudio Soto, Brit Mollenhauer, Oskar Hansson, Un Jung Kang, Roy N. Alcalay, David G. Standaert, Claudia Trenkwalder, Kenneth Marek, Douglas Galasko, Kathleen L. Poston	5
2	Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer’s disease 2025 ·Science Advances ·Andi Liu, (unknown), (unknown), Xian Chen, (unknown), (unknown), (unknown), Astrid M. Manuel, (unknown), Brisa S. Fernandes, Meifang Yu, Paul E. Schulz, Lukas M. Simon, Claudio Soto, Zhongming Zhao	0
3	Donation After Circulatory Death Heart Transplantation - Withdrawal Practices and Location Matter! 2024 ·The Journal of Heart and Lung Transplantation ·(unknown), (unknown), (unknown), Jeanette E. Villanueva, Seungchan Kim, (unknown), Claudio Soto, (unknown), (unknown), (unknown), Emily Granger, P. Jansz, (unknown)	1
4	Adaptation of the protein misfolding cyclic amplification (PMCA) technique for the screening of anti‐prion compounds 2024 ·The FASEB Journal ·(unknown), (unknown), (unknown), (unknown), (unknown), Claudio Soto, Rodrigo Morales	1
5	Detection of prions in the urine of patients affected by sporadic Creutzfeldt–Jakob disease 2023 ·Annals of Clinical and Translational Neurology ·Sandra Pritzkow, (unknown), (unknown), Paul E. Schulz, Brian S. Appleby, Fabio Moda, Santiago Ramírez, Silvio Notari, Pierluigi Gambetti, Claudio Soto	4
6	Plasma Exchange Reduces Aβ Levels in Plasma and Decreases Amyloid Plaques in the Brain in a Mouse Model of Alzheimer’s Disease 2023 ·International Journal of Molecular Sciences ·Santiago Ramírez, (unknown), (unknown), (unknown), (unknown), Tyler Allison, Natália Pessoa Rocha, (unknown), Claudio Soto	7
7	Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease 2022 ·Acta Neuropathologica Communications ·Natalia Salvadores, Inés Moreno‐González, Nazaret Gamez, (unknown), (unknown), (unknown), Sebastián Jiménez, Javier Vitórica, Antonia Gutiérrez, Claudio Soto, Felipe A. Court	51
8	Preventive and therapeutic reduction of amyloid deposition and behavioral impairments in a model of Alzheimer’s disease by whole blood exchange 2022 ·Molecular Psychiatry ·Akihiko Urayama, Inés Moreno‐González, Diego Morales‐Scheihing, (unknown), Sandra Pritzkow, Claudio Soto	21
9	Longitudinal Assessment of Tau-Associated Pathology by 18F-THK5351 PET Imaging: A Histological, Biochemical, and Behavioral Study 2021 ·Diagnostics ·Inés Moreno‐González, George A. Edwards, Omar Hasan, Nazaret Gamez, (unknown), Juan José Fernandez-Valenzuela, Antonia Gutiérrez, Claudio Soto, Paul E. Schulz	3
10	The ecology of chronic wasting disease in wildlife 2019 ·Biological reviews/Biological reviews of the Cambridge Philosophical Society ·Luis E. Escobar, Sandra Pritzkow, (unknown), Daniel A. Grear, (unknown), (unknown), Gustavo Machado, A. Townsend Peterson, Claudio Soto	49
11	Peripheral Delivery of Neural Precursor Cells Ameliorates Parkinson’s Disease-Associated Pathology 2019 ·Cells ·George A. Edwards, Nazaret Gamez, Enrique Armijo, (unknown), Rodrigo Morales, (unknown), Paul E. Schulz, Claudio Soto, Inés Moreno‐González	7
12	1,2,4‐trihydroxynaphthalene‐2‐O‐β‐D‐glucopyranoside delays amyloid‐β₄₂ aggregation and reduces amyloid cytotoxicity 2018 ·BioFactors ·(unknown), Manuela Leri, Monica Bucciantini, Massimo Stefani, (unknown), Borhane Mahjoub, Hichem Ben Jannet, Jérôme Guillard, Riadh Ksouri, Moufida Saïdani Tounsi, Claudio Soto, El Akrem Hayouni	4
13	Strain-dependent profile of misfolded prion protein aggregates 2016 ·Scientific Reports ·Rodrigo Morales, Ping Ping Hu, Claudia Duran‐Aniotz, Fabio Moda, Rodrigo Díaz‐Espinoza, Baian Chen, Javiera Bravo‐Alegria, Natallia Makarava, Ilia V. Baskakov, Claudio Soto	32
14	Correction: De Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype 2013 ·PLoS Pathogens ·Marcelo A. Barria, Abhisek Mukherjee, Dennisse Gonzalez-Romero, Rodrigo Morales, Claudio Soto	1
15	High-resolution structure of infectious prion protein: the final frontier 2012 ·Nature Structural & Molecular Biology ·Rodrigo Díaz‐Espinoza, Claudio Soto	98
16	Correction: Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress 2011 ·PLoS ONE ·Mauricio Torres, Karen Castillo, (unknown), (unknown), Claudio Soto, Claudio Hetz	3
17	Abnormal calcium homeostasis and protein folding stress at the ER 2011 ·Communicative & Integrative Biology ·Mauricio Torres, (unknown), Claudio Soto, Claudio Hetz	30
18	Crossing the Species Barrier by PrPSc Replication In Vitro Generates Unique Infectious Prions 2008 ·Cell ·Joaquı́n Castilla, Dennisse Gonzalez-Romero, Paula Saá, Rodrigo Morales, Jorge de Castro, Claudio Soto	158
19	Presymptomatic Detection of Prions in Blood 2006 ·Science ·Paula Saá, Joaquı́n Castilla, Claudio Soto	174
20	Protein Misfolding Cyclic Amplification for Diagnosis and Prion Propagation Studies 2006 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Joaquı́n Castilla, Paula Saá, Rodrigo Morales, Karim Abid, Kinsey Maundrell, Claudio Soto	114

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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