David M. Valenzuela

31.4k total citations · 13 hit papers
110 papers, 21.8k citations indexed

About

David M. Valenzuela is a scholar working on Molecular Biology, Immunology and Cellular and Molecular Neuroscience. According to data from OpenAlex, David M. Valenzuela has authored 110 papers receiving a total of 21.8k indexed citations (citations by other indexed papers that have themselves been cited), including 63 papers in Molecular Biology, 27 papers in Immunology and 16 papers in Cellular and Molecular Neuroscience. Recurrent topics in David M. Valenzuela's work include Immune Cell Function and Interaction (10 papers), Angiogenesis and VEGF in Cancer (9 papers) and Pluripotent Stem Cells Research (8 papers). David M. Valenzuela is often cited by papers focused on Immune Cell Function and Interaction (10 papers), Angiogenesis and VEGF in Cancer (9 papers) and Pluripotent Stem Cells Research (8 papers). David M. Valenzuela collaborates with scholars based in United States, Switzerland and Germany. David M. Valenzuela's co-authors include George D. Yancopoulos, Andrew Murphy, David J. Glass, Trevor N. Stitt, Thomas M. DeChiara, William Poueymirou, Richard A. Flavell, Margaret Karow, Sean Stevens and Esther Latres and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

David M. Valenzuela

110 papers receiving 21.5k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

2001 2.8k citations Sue C. Bodine, Esther Latres et al. Science profile →
Regulation of the Germinal Center Response by MicroRNA-155

2007 1.2k citations Andrew Murphy, David Frendewey et al. Science profile →
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation

2007 1.0k citations David B. Lombard, Frederick W. Alt et al. Molecular and Cellular Biology profile →
SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

2006 930 citations Marcia C. Haigis, Raúl Mostoslavsky et al. profile →
The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 749 citations Thomas M. DeChiara, David C. Bowen et al. profile →
Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis

1996 731 citations Nicholas W. Gale, David M. Valenzuela et al. profile →
CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors

2008 731 citations Andrew Murphy, David M. Valenzuela et al. Journal of Clinical Investigation profile →
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1991 722 citations Trevor N. Stitt, David J. Glass et al. profile →
Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease

2008 674 citations Lauren A. Zenewicz, George D. Yancopoulos et al. Immunity profile →
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

2012 583 citations Lauren A. Zenewicz, Andrew Murphy et al. profile →
Agrin Acts via a MuSK Receptor Complex

1996 557 citations David J. Glass, David C. Bowen et al. profile →
Interleukin-22 but Not Interleukin-17 Provides Protection to Hepatocytes during Acute Liver Inflammation

2007 522 citations Lauren A. Zenewicz, George D. Yancopoulos et al. Immunity profile →
The Receptor for Ciliary Neurotrophic Factor

1991 516 citations David M. Valenzuela, George D. Yancopoulos et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David M. Valenzuela United States	60	11.3k	4.2k	3.9k	3.3k	2.4k	110	21.8k
Stefan Offermanns Germany	91	18.1k 1.6×	3.5k 0.9×	5.1k 1.3×	6.3k 1.9×	2.4k 1.0×	376	31.8k
Tetsuo Noda Japan	80	15.6k 1.4×	2.7k 0.6×	2.1k 0.6×	1.8k 0.6×	2.9k 1.2×	260	24.3k
Shigeyoshi Itohara Japan	84	10.2k 0.9×	4.6k 1.1×	7.2k 1.9×	2.4k 0.7×	2.6k 1.1×	277	25.4k
Daniel Metzger France	85	16.5k 1.5×	3.5k 0.8×	2.3k 0.6×	2.8k 0.9×	3.9k 1.6×	200	26.8k
Nigel W. Bunnett United States	87	9.3k 0.8×	3.1k 0.8×	8.4k 2.2×	6.3k 1.9×	2.2k 0.9×	358	29.5k
Lino Tessarollo United States	79	11.0k 1.0×	2.6k 0.6×	5.6k 1.5×	1.7k 0.5×	2.2k 0.9×	247	21.2k
Hartwig Wolburg Germany	75	10.9k 1.0×	1.6k 0.4×	3.8k 1.0×	2.7k 0.8×	2.5k 1.0×	279	22.1k
Anthony Wynshaw‐Boris United States	85	18.8k 1.7×	2.5k 0.6×	3.3k 0.9×	2.0k 0.6×	4.1k 1.7×	204	27.9k
Stanley J. Wiegand United States	71	13.8k 1.2×	1.8k 0.4×	7.3k 1.9×	2.3k 0.7×	3.9k 1.6×	150	29.2k
Min Lü United States	81	13.2k 1.2×	2.1k 0.5×	1.1k 0.3×	2.1k 0.6×	1.9k 0.8×	227	21.4k

Countries citing papers authored by David M. Valenzuela

Since Specialization

Citations

This map shows the geographic impact of David M. Valenzuela's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David M. Valenzuela with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David M. Valenzuela more than expected).

Fields of papers citing papers by David M. Valenzuela

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David M. Valenzuela. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David M. Valenzuela. The network helps show where David M. Valenzuela may publish in the future.

Co-authorship network of co-authors of David M. Valenzuela

This figure shows the co-authorship network connecting the top 25 collaborators of David M. Valenzuela. A scholar is included among the top collaborators of David M. Valenzuela based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David M. Valenzuela. David M. Valenzuela is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Coyago-Cruz, Elena, et al.. (2024). Bioactive Compound Profiling and Antioxidant Activity of Phytelephas tenuicaulis and Other Amazonian Fruits. Foods. 13(13). 2151–2151. 5 indexed citations

Morris, Melanie, et al.. (2018). Developmental nicotine exposure affects larval brain size and the adult dopaminergic system of Drosophila melanogaster. BMC Developmental Biology. 18(1). 13–13. 14 indexed citations

Lai, Ka‐Man Venus, Guochun Gong, Amanda Atanasio, et al.. (2015). Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs. PLoS ONE. 10(4). e0125522–e0125522. 49 indexed citations

Bouleti, Claire, Thomas Mathivet, Bérard Coqueran, et al.. (2013). Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke. European Heart Journal. 34(47). 3657–3668. 61 indexed citations

McGee, Heather M., Barbara Schmidt, Carmen J. Booth, et al.. (2012). IL-22 Promotes Fibroblast-Mediated Wound Repair in the Skin. Journal of Investigative Dermatology. 133(5). 1321–1329. 132 indexed citations

Perdiguero, Elisa Gomez, Ariane Galaup, Mélanie Durand, et al.. (2011). Alteration of Developmental and Pathological Retinal Angiogenesis in angptl4-deficient Mice. Journal of Biological Chemistry. 286(42). 36841–36851. 62 indexed citations

Zhao, Tong‐Jin, Guosheng Liang, Xuefen Xie, et al.. (2010). Ghrelin O -acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice. Proceedings of the National Academy of Sciences. 107(16). 7467–7472. 358 indexed citations

Demaria, Olivier, Philippe P. Pagni, Stephanie Traub, et al.. (2010). TLR8 deficiency leads to autoimmunity in mice. Journal of Clinical Investigation. 120(10). 3651–62. 154 indexed citations

Cohen, Shenhav, Jeffrey J. Brault, Steven P. Gygi, et al.. (2009). During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. The Journal of Cell Biology. 185(6). 1083–1095. 472 indexed citations

10.

Li, Zhe, Hui Huang, Patricia Boland, et al.. (2009). Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis. Proceedings of the National Academy of Sciences. 106(52). 22399–22404. 28 indexed citations

11.

Leppkes, Moritz, Christoph Becker, Ivaylo I. Ivanov, et al.. (2008). RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F. Gastroenterology. 136(1). 257–267. 366 indexed citations

12.

Weigmann, Benno, Hans A. Lehr, George D. Yancopoulos, et al.. (2008). The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis. The Journal of Experimental Medicine. 205(9). 2099–2110. 90 indexed citations

13.

Zenewicz, Lauren A., George D. Yancopoulos, David M. Valenzuela, et al.. (2007). Interleukin-22 but Not Interleukin-17 Provides Protection to Hepatocytes during Acute Liver Inflammation. Immunity. 27(4). 647–659. 522 indexed citations breakdown →

14.

Lombard, David B., Frederick W. Alt, Hwei-Ling Cheng, et al.. (2007). Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation. Molecular and Cellular Biology. 27(24). 8807–8814. 1011 indexed citations breakdown →

15.

Tanaka, Mari, Tomohiko Okuda, Aris N. Economides, et al.. (2007). Expression of BMP-7 and USAG-1 (a BMP antagonist) in kidney development and injury. Kidney International. 73(2). 181–191. 60 indexed citations

16.

Becker, Christoph, Heike Dornhoff, Clemens Neufert, et al.. (2006). Cutting Edge: IL-23 Cross-Regulates IL-12 Production in T Cell-Dependent Experimental Colitis. The Journal of Immunology. 177(5). 2760–2764. 186 indexed citations

17.

Hogan, Simon P., Luqman Seidu, Carine Blanchard, et al.. (2006). Resistin-like molecule β regulates innate colonic function: Barrier integrity and inflammation susceptibility. Journal of Allergy and Clinical Immunology. 118(1). 257–268. 131 indexed citations

18.

Bodine, Sue C., Esther Latres, Susanne Baumhueter, et al.. (2001). Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy. Science. 294(5547). 1704–1708. 2828 indexed citations breakdown →

19.

Bowen, David C., John S. Park, Sue C. Bodine, et al.. (1998). Localization and Regulation of MuSK at the Neuromuscular Junction. Developmental Biology. 199(2). 309–319. 80 indexed citations

20.

Raychaudhuri, Pradip, E A Stringer, David M. Valenzuela, & Umadas Maitra. (1984). Ribosomal subunit antiassociation activity in rabbit reticulocyte lysates. Evidence for a low molecular weight ribosomal subunit antiassociation protein factor (Mr = 25,000).. Journal of Biological Chemistry. 259(19). 11930–11935. 37 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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