Gavin Thurston

31.0k total citations · 16 hit papers
168 papers, 22.1k citations indexed

About

Gavin Thurston is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Gavin Thurston has authored 168 papers receiving a total of 22.1k indexed citations (citations by other indexed papers that have themselves been cited), including 109 papers in Molecular Biology, 64 papers in Oncology and 33 papers in Cancer Research. Recurrent topics in Gavin Thurston's work include Angiogenesis and VEGF in Cancer (86 papers), Lipid metabolism and disorders (24 papers) and Cancer, Hypoxia, and Metabolism (24 papers). Gavin Thurston is often cited by papers focused on Angiogenesis and VEGF in Cancer (86 papers), Lipid metabolism and disorders (24 papers) and Cancer, Hypoxia, and Metabolism (24 papers). Gavin Thurston collaborates with scholars based in United States, Canada and United Kingdom. Gavin Thurston's co-authors include Donald M. McDonald, George D. Yancopoulos, Peter Bałuk, Nicholas W. Gale, Hellmut G. Augustin, Kari Alitalo, Christopher Daly, Joyce McClain, Chitra Suri and Gou Young Koh and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Gavin Thurston

164 papers receiving 21.7k citations

Hit Papers

Openings between Defectiv... 1998 2026 2007 2016 2000 1999 2009 2000 2006 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness
    2000 1.3k citations Gavin Thurston, Donald M. McDonald et al. profile →
  2. Leakage-Resistant Blood Vessels in Mice Transgenically Overexpressing Angiopoietin-1
    1999 1.1k citations Gavin Thurston, George D. Yancopoulos et al. profile →
  3. Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
    2009 1.1k citations Hellmut G. Augustin, Gavin Thurston et al. profile →
  4. Angiopoietin-1 protects the adult vasculature against plasma leakage
    2000 1.1k citations Gavin Thurston, John S. Rudge et al. profile →
  5. Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
    2006 824 citations Irene Noguera‐Troise, Christopher Daly et al. profile →
  6. Angiopoietin-2 Is Required for Postnatal Angiogenesis and Lymphatic Patterning, and Only the Latter Role Is Rescued by Angiopoietin-1
    2002 785 citations Nicholas W. Gale, Gavin Thurston et al. profile →
  7. Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation
    2006 741 citations Ulrike Fiedler, Gavin Thurston et al. profile →
  8. CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors
    2008 731 citations Andrew Murphy, David M. Valenzuela et al. Journal of Clinical Investigation profile →
  9. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
    2010 719 citations Gavin Thurston et al. profile →
  10. Increased Vascularization in Mice Overexpressing Angiopoietin-1
    1998 680 citations Gavin Thurston, Donald M. McDonald et al. profile →
  11. VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
    2005 630 citations Barbara Sennino, Gavin Thurston et al. American Journal of Physiology-Heart and Circulatory Physiology profile →
  12. Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting
    2007 597 citations Ivan B. Lobov, Nicholas W. Gale et al. Proceedings of the National Academy of Sciences profile →
  13. Inhibition of Vascular Endothelial Growth Factor (VEGF) Signaling in Cancer Causes Loss of Endothelial Fenestrations, Regression of Tumor Vessels, and Appearance of Basement Membrane Ghosts
    2004 589 citations Fabienne Baffert, Dana D. Hu‐Lowe et al. profile →
  14. The Tie-2 ligand Angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies
    2004 585 citations Ulrike Fiedler, Gavin Thurston et al. profile →
  15. Vascular endothelial–cadherin is an important determinant of microvascular integrityinvivo
    1999 561 citations Gavin Thurston, Donald M. McDonald et al. Proceedings of the National Academy of Sciences profile →
  16. Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice
    2001 518 citations Gavin Thurston, Donald M. McDonald et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Gavin Thurston 13.8k 5.5k 4.1k 2.3k 2.3k 168 22.1k
Hellmut G. Augustin 11.0k 0.8× 4.3k 0.8× 3.4k 0.8× 1.4k 0.6× 2.7k 1.1× 206 19.0k
Michael Zeisberg 10.6k 0.8× 5.6k 1.0× 3.6k 0.9× 3.3k 1.4× 2.1k 0.9× 105 21.1k
Patrìcia A. D'Amore 17.0k 1.2× 3.6k 0.7× 3.9k 0.9× 2.2k 0.9× 2.5k 1.1× 233 30.0k
M. Luisa Iruela‐Arispe 12.5k 0.9× 3.1k 0.6× 5.0k 1.2× 1.9k 0.8× 2.8k 1.2× 202 21.4k
Hans‐Peter Gerber 12.1k 0.9× 5.7k 1.0× 4.6k 1.1× 2.5k 1.1× 2.2k 1.0× 91 21.1k
Lawrence F. Brown 13.7k 1.0× 6.1k 1.1× 5.2k 1.2× 2.4k 1.0× 2.7k 1.2× 111 23.2k
David Lyden 12.7k 0.9× 7.0k 1.3× 6.5k 1.6× 2.4k 1.0× 3.2k 1.4× 104 21.4k
Alexandra Aicher 11.9k 0.9× 5.3k 1.0× 3.5k 0.8× 1.5k 0.6× 2.9k 1.3× 86 19.9k
Rolf A. Brekken 9.3k 0.7× 6.4k 1.2× 4.4k 1.1× 1.7k 0.7× 3.5k 1.5× 271 19.5k
Eli Keshet 13.3k 1.0× 2.9k 0.5× 6.5k 1.6× 2.5k 1.1× 3.2k 1.4× 117 23.4k

Countries citing papers authored by Gavin Thurston

Since Specialization
Citations

This map shows the geographic impact of Gavin Thurston's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gavin Thurston with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gavin Thurston more than expected).

Fields of papers citing papers by Gavin Thurston

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gavin Thurston. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gavin Thurston. The network helps show where Gavin Thurston may publish in the future.

Co-authorship network of co-authors of Gavin Thurston

This figure shows the co-authorship network connecting the top 25 collaborators of Gavin Thurston. A scholar is included among the top collaborators of Gavin Thurston based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gavin Thurston. Gavin Thurston is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kim, Sungsoo, Subrata Chowdhury, Carrie J. Shawber, et al.. (2023). Angiopoietin-2–Dependent Spatial Vascular Destabilization Promotes T-cell Exclusion and Limits Immunotherapy in Melanoma. Cancer Research. 83(12). 1968–1983. 24 indexed citations
2.
Chowdhury, Subrata, Sungsoo Kim, Richard A. Friedman, et al.. (2023). Angiopoietin-2 blockade suppresses growth of liver metastases from pancreatic neuroendocrine tumors by promoting T cell recruitment. Journal of Clinical Investigation. 133(20). 8 indexed citations
3.
Chiu, Danica, Richard Tavaré, Lauric Haber, et al.. (2020). A PSMA-Targeting CD3 Bispecific Antibody Induces Antitumor Responses that Are Enhanced by 4-1BB Costimulation. Cancer Immunology Research. 8(5). 596–608. 33 indexed citations
4.
Young, Tara M., Claudia Reyes, Elizabeth Pasnikowski, et al.. (2020). Autophagy protects tumors from T cell–mediated cytotoxicity via inhibition of TNFα-induced apoptosis. Science Immunology. 5(54). 79 indexed citations
5.
DaSilva, John O., Andrés E. Perez Bay, Julian Andreev, et al.. (2019). A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models. Clinical Cancer Research. 26(6). 1408–1419. 23 indexed citations
6.
Burova, Elena, Aynur Hermann, Jie Dai, et al.. (2019). Preclinical Development of the Anti-LAG-3 Antibody REGN3767: Characterization and Activity in Combination with the Anti-PD-1 Antibody Cemiplimab in Human PD-1xLAG-3 –Knockin Mice. Molecular Cancer Therapeutics. 18(11). 2051–2062. 62 indexed citations
7.
Zhao, Qi, Alexandra Eichten, Asma Parveen, et al.. (2018). Single-Cell Transcriptome Analyses Reveal Endothelial Cell Heterogeneity in Tumors and Changes following Antiangiogenic Treatment. Cancer Research. 78(9). 2370–2382. 142 indexed citations
8.
Kelly, Marcus P., Carlos Hickey, Sosina Makonnen, et al.. (2017). Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody–Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers. Molecular Cancer Therapeutics. 16(7). 1299–1311. 19 indexed citations
9.
Eichten, Alexandra, Alexander P. Adler, Li Zhang, et al.. (2016). Resistance to Anti-VEGF Therapy Mediated by Autocrine IL6/STAT3 Signaling and Overcome by IL6 Blockade. Cancer Research. 76(8). 2327–2339. 47 indexed citations
10.
Cheung, Eunice, Angela Sun, Frank Kuhnert, et al.. (2016). An assessment of the angiogenic effects of VEGF-A and ANGPTL4 in the mouse retina.. Investigative Ophthalmology & Visual Science. 57(12). 121–121. 2 indexed citations
11.
Kuhnert, Frank, Guoying Chen, Sandra Coetzee, et al.. (2015). Dll4 Blockade in Stromal Cells Mediates Antitumor Effects in Preclinical Models of Ovarian Cancer. Cancer Research. 75(19). 4086–4096. 37 indexed citations
12.
Zhang, Li, Carla Castanaro, Jeanette Fairhurst, et al.. (2014). ERBB3/HER2 Signaling Promotes Resistance to EGFR Blockade in Head and Neck and Colorectal Cancer Models. Molecular Cancer Therapeutics. 13(5). 1345–1355. 42 indexed citations
13.
Bouleti, Claire, Thomas Mathivet, Bérard Coqueran, et al.. (2013). Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke. European Heart Journal. 34(47). 3657–3668. 61 indexed citations
14.
Daly, Christopher, Alexandra Eichten, Carla Castanaro, et al.. (2012). Angiopoietin-2 Functions as a Tie2 Agonist in Tumor Models, Where It Limits the Effects of VEGF Inhibition. Cancer Research. 73(1). 108–118. 180 indexed citations
15.
Perdiguero, Elisa Gomez, Ariane Galaup, Mélanie Durand, et al.. (2011). Alteration of Developmental and Pathological Retinal Angiogenesis in angptl4-deficient Mice. Journal of Biological Chemistry. 286(42). 36841–36851. 62 indexed citations
16.
Nasarre, Patrick, Markus Thomas, Karoline Kruse, et al.. (2009). Host-Derived Angiopoietin-2 Affects Early Stages of Tumor Development and Vessel Maturation but Is Dispensable for Later Stages of Tumor Growth. Cancer Research. 69(4). 1324–1333. 140 indexed citations
17.
Li, Zhe, Hui Huang, Patricia Boland, et al.. (2009). Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis. Proceedings of the National Academy of Sciences. 106(52). 22399–22404. 28 indexed citations
18.
Adler, Alexander P., Alexandra Eichten, Yi Wei, et al.. (2008). Identifying tumor vascular genes regulated by Aflibercept (VEGF Trap). Cancer Research. 68. 2497–2497. 1 indexed citations
19.
Adler, Alexander P., et al.. (2007). Rapid effects of VEGF Trap on angiogenesis and tumor cell proliferation. Cancer Research. 67. 2127–2127. 1 indexed citations
20.
Baffert, Fabienne, Tom Le, Barbara Sennino, et al.. (2005). Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling. American Journal of Physiology-Heart and Circulatory Physiology. 290(2). H547–H559. 277 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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