Jean E. Lachowicz

5.4k citations

84 papers · 4.3k indexed · h-index 33

Impact in

Physiology top 0.5%
- Adenosine and Purinergic Signaling
Cellular and Molecular Neuroscience top 0.5%
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology

Papers in

Physiology 13
- Adenosine and Purinergic Signaling 13
Cellular and Molecular Neuroscience 39
- Neuropeptides and Animal Physiology 20
- Neuroscience and Neuropharmacology Research 17
- Neurotransmitter Receptor Influence on Behavior 13

Co-authors: David R. Sibley Frederick J. Monsma John Drago Ruth A. Duffy C R Gerfen Heinz Steiner Mark W. Hamblin Geoffrey B. Varty
Journals: Bioorganic & Medicinal Chemistry Letters (37 papers)Journal of Medicinal Chemistry (3 papers)Cancer Research (3 papers)Journal of Clinical Investigation (2 papers)Proceedings of the National Academy of Sciences (2 papers)
Partner nations: United States United Kingdom Canada

In The Last Decade

Jean E. Lachowicz

83 papers receiving 4.1k citations

Peers

Countries citing papers authored by Jean E. Lachowicz

Since Specialization

Citations

This map shows the geographic impact of Jean E. Lachowicz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean E. Lachowicz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean E. Lachowicz more than expected).

Fields of papers citing papers by Jean E. Lachowicz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean E. Lachowicz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean E. Lachowicz. The network helps show where Jean E. Lachowicz may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jean E. Lachowicz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jean E. Lachowicz Line = papers co-authored together Jean E. Lachowicz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Cigarette Smoke-Induced Oxidative Stress and Autophagy in Human Alveolar Epithelial Cell Line (A549 Cells) Advances in experimental medicine and biology ·BM Scalet, Jean E. Lachowicz, Mayra Reyes Becerra, Jolanta Ignatowska, Adrian P. Rybak, P Camara, Adam Hołownia	2019	9
2	Cytotoxicity, Oxidative Stress, and Autophagy in Human Alveolar Epithelial Cell Line (A549 Cells) Exposed to Standardized Urban Dust Advances in experimental medicine and biology ·Jolanta Ignatowska, Mayra Reyes Becerra, Martina Parente, BM Scalet, Jean E. Lachowicz, Adam Hołownia	2019	10
3	ANG4043, a Novel Brain-Penetrant Peptide–mAb Conjugate, Is Efficacious against HER2-Positive Intracranial Tumors in Mice Molecular Cancer Therapeutics ·Anthony Régina, Michel Demeule, Sasmita Tripathy, Simon Lord‐Dufour, Jean-Christophe Currie, 宇津木聡, Borhane Annabi, Jean‐Paul Castaigne, Jean E. Lachowicz	2014	88
4	Synthesis and structure–activity relationship (SAR) study of 4-azabenzoxazole analogues as H3 antagonists Bioorganic & Medicinal Chemistry Letters ·Ning Shao, Robert Aslanian, Robert E. West, Shirley M. Williams, Renlong Wu, Joyce Hwa, Jeremiah Conway, Jean E. Lachowicz, Anandan Palani	2012	4
5	Fused bicycles as arylketone bioisosteres leading to potent, orally active thiadiazole H3 antagonists Bioorganic & Medicinal Chemistry Letters ·Dong Xiao, Anandan Palani, I Chramtsov, Robert Aslanian, Robert E. West, Shirley M. Williams, Renlong Wu, Joyce Hwa, Jeremiah Conway, Jean E. Lachowicz, Walter A. Korfmacher	2012	3
6	Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1) Bioorganic & Medicinal Chemistry Letters ·Yongqi Deng, Zhiwei Yang, Gerald W. Shipps, Adriana Flores-López, Robert West, Joyce Hwa, Shuqin Zheng, Constance Farley, Jean E. Lachowicz, Margaret van Heek, Alan Bass, Dinesh P. Sinha, Adrian Lison, Mark E. Cartwright	2012	15
7	Lead optimization of a pyridine-carboxamide series as DGAT-1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Pauline C. Ting, Vanessa Moll, Nicolas F. Zorn, Hyunjin M. Kim, Robert Aslanian, Mingxiang Lin, Michelle Smith, Scott S. Walker, John A. Cook, Margaret van Heek, Jean E. Lachowicz	2012	8
8	Discovery of a series of potent, orally active α,α-disubstituted piperidine NK1 antagonists Bioorganic & Medicinal Chemistry Letters ·Dong Xiao, Cheng Wang, Anandan Palani, Hon‐Chung Tsui, Gregory A. Reichard, Sunil Paliwal, Neng‐Yang Shih, Robert Aslanian, Ruth A. Duffy, Jean E. Lachowicz, Geoffrey B. Varty, Cynthia A. Morgan, Fei Liu, Amin A. Nomeir	2010	10
9	Synthesis and structure–activity relationships of 2-(1,4′-bipiperidin-1′-yl)thiazolopyridine as H3 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Y Kristianto, Anandan Palani, Xiao Cheng, Ying Huang, Robert Aslanian, Robert E. West, Shirley M. Williams, Renlong Wu, Joyce Hwa, Jeremiah Conway, Jean E. Lachowicz	2009	32
10	Characterization of the Potent and Highly Selective A2A Receptor Antagonists Preladenant and SCH 412348 [7-[2-[4-2,4-Difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in Rodent Models of Movement Disorders and Depression Journal of Pharmacology and Experimental Therapeutics ·Robert A. Hodgson, Rosalia Bertorelli, Geoffrey B. Varty, Jean E. Lachowicz, A Forlani, Silva Fredduzzi, Mary Cohen-Williams, Guy A. Higgins, Francesco Impagnatiello, Kuei-Yu Chen, Leonard E. Parra, Carolyn Foster, Ying Zhai, Ian D. Stewart, Andrew W. Stamford, Eric M. Parker, Angelo Reggiani, John C. Hunter	2009	128
11	Cyclobutane derivatives as potent NK1 selective antagonists Bioorganic & Medicinal Chemistry Letters ·Marvelous Aigbedion, Gregory A. Reichard, Sunil Paliwal, Sapna Shah, Hon‐Chung Tsui, Ruth A. Duffy, Jean E. Lachowicz, Cynthia A. Morgan, Geoffrey B. Varty, Neng‐Yang Shih	2006	45
12	Cyclic urea derivatives as potent NK1 selective antagonists Bioorganic & Medicinal Chemistry Letters ·Ho‐Jane Shue, Xiao Chen, Neng‐Yang Shih, David J. Blythin, Sunil Paliwal, Ling Lin, Aurelia Genco, Ye.N. Rosenvasser, Sapna Shah, Gregory A. Reichard, John J. Piwinski, Ruth A. Duffy, Jean E. Lachowicz, Vicki L. Coffin, Fei Liu, Amin A. Nomeir, Cynthia A. Morgan, Geoffrey B. Varty	2005	40
13	WGA-Coated Yttrium Oxide Beads Enable an Imaging-Based Adenosine 2a Receptor Binding Scintillation Proximity Assay Suitable for High Throughput Screening Assay and Drug Development Technologies ·Robert W. Bryant, 正人長嶋, 素女浅野, L. H. Michael, 直樹内野, Corina Panaitescu, Reginald P.R. Pascoe Am DVSc FRCVSm FACVSc, Ying Zhai, Jean E. Lachowicz	2004	8
14	Phenotypic analysis of dopamine receptor knockout mice; recent insights into the functional specificity of dopamine receptor subtypes Neuropharmacology ·Andrew Holmes, Jean E. Lachowicz, David R. Sibley	2004	97
15	Synthesis and structure–Activity relationships of M2-Selective muscarinic receptor ligands in the 1-[4-(4-Arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family Bioorganic & Medicinal Chemistry Letters ·Stuart W. McCombie, B. G. Lopes, Jayaram R. Tagat, Dennis V. Nazareno, Susan F. Vice, Jennifer Lynn Ford, Theodros Asberom, Tetsuo MATSMOTO, Joseph A. Kozlowski, Guowei Zhou, Vilma Ruperto, Ruth A. Duffy, Jean E. Lachowicz	2002	8
16	Correlation of Neurokinin (NK) 1 Receptor Occupancy in Gerbil Striatum with Behavioral Effects of NK1 Antagonists Journal of Pharmacology and Experimental Therapeutics ·Ruth A. Duffy, Geoffrey B. Varty, Cynthia A. Morgan, Jean E. Lachowicz	2002	47
17	ADP Is the Cognate Ligand for the Orphan G Protein-coupled Receptor SP1999 Journal of Biological Chemistry ·Fang L. Zhang, Lin Luo, Eric L. Gustafson, Jean E. Lachowicz, Michelle Smith, Xudong Qiao, Yan‐Hui Liu, Guodong Chen, Birendra Pramanik, Thomas M. Laz, Silverio de Santa Teresa, Marvin Bayne, Frederick J. Monsma	2001	178
18	Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs Journal of Clinical Investigation ·Carolyn Foster, Iwona Foryś, I. Trautschold, Ying Zhai, Michelle Smith, Jean E. Lachowicz, Fang L. Zhang, Eric L. Gustafson, Frederick J. Monsma, Maria Wiekowski, Susan J. Abbondanzo, Donald N. Cook, Marvin Bayne, Sérgio A. Lira, Madhu Chintala	2001	330
19	SCH 57790: A novel M2 receptor selective antagonist Life Sciences ·Jean E. Lachowicz, Derek Lowe, Ruth A. Duffy, Vilma Ruperto, Lisa A. Taylor, Henry Guzik, Eleonora Troiani, Joel G. Berger, 황명현, Xie Kele, Joseph A. Kozlowski, John W. Clader, Catherine D. Strader, Nicholas Murgolo	1999	19
20	The D2S and D2L dopamine receptor isoforms are differentially regulated in Chinese hamster ovary cells. Molecular Pharmacology ·W.L. Liu, Jean E. Lachowicz, David R. Sibley	1994	66

About Jean E. Lachowicz

Jean E. Lachowicz is a scholar working on Physiology, Cellular and Molecular Neuroscience, Molecular Biology, Biochemistry and Organic Chemistry, having authored 84 papers that have together received 4.3k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (41 papers), Neuropeptides and Animal Physiology (20 papers), Neuroscience and Neuropharmacology Research (17 papers), Neurotransmitter Receptor Influence on Behavior (13 papers), Adenosine and Purinergic Signaling (13 papers), Pharmacological Receptor Mechanisms and Effects (11 papers), Synthesis and Biological Evaluation (6 papers) and Phenothiazines and Benzothiazines Synthesis and Activities (6 papers). The work is most often cited by research in Physiology (551 citations), Cellular and Molecular Neuroscience (1.9k citations), Molecular Biology (2.1k citations), Endocrine and Autonomic Systems (188 citations) and Organic Chemistry (764 citations). Jean E. Lachowicz has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include David R. Sibley, Frederick J. Monsma, John Drago, Ruth A. Duffy, C R Gerfen, Heinz Steiner, Mark W. Hamblin, Geoffrey B. Varty, Yong Shen and Michelle Smith. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Cancer Research, Journal of Clinical Investigation and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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