K.A. Bennett

2.9k citations

18 papers · 2.2k indexed · 1 hit paper · h-index 13

Impact in

Physiology top 0.5%
- Adenosine and Purinergic Signaling
Cellular and Molecular Neuroscience top 2%
- Neuropeptides and Animal Physiology
- Neuroscience and Neuropharmacology Research

Papers in ⓘ

Physiology 5
- Adenosine and Purinergic Signaling 5
Cellular and Molecular Neuroscience 11
- Neuropeptides and Animal Physiology 7
- Neuroscience and Neuropharmacology Research 5

Co-authors: Christopher G. Tate (4 shared papers)Guillaume Lebon (3 shared papers)Christopher J. Langmead (3 shared papers)Fiona H. Marshall (7 shared papers)Tony Warne (1 shared paper)Patricia C. Edwards (1 shared paper)Andrew G. W. Leslie (1 shared paper)A.S. Dore (6 shared papers)
Journals: Nature (3 papers)Journal of Medicinal Chemistry (2 papers)Molecular Pharmacology (2 papers)ACS Pharmacology & Translational Science (1 paper)European Journal of Endocrinology (1 paper)
Partner nations: United Kingdom Italy United States

In The Last Decade

K.A. Bennett

18 papers receiving 2.1k citations

Hit Papers

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation 2011 · 700 citations

Peers

Countries citing papers authored by K.A. Bennett

Since Specialization

Citations

This map shows the geographic impact of K.A. Bennett's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by K.A. Bennett with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites K.A. Bennett more than expected).

Fields of papers citing papers by K.A. Bennett

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by K.A. Bennett. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by K.A. Bennett. The network helps show where K.A. Bennett may publish in the future.

Co-authors

The 25 scholars most cited alongside K.A. Bennett, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with K.A. Bennett Line = papers co-authored together K.A. Bennett links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation Nature ·Guillaume Lebon, Tony Warne, Patricia C. Edwards, K.A. Bennett, Christopher J. Langmead, Andrew G. W. Leslie, Christopher G. Tate Hit paper breakdown →	2011	700
2	Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine Structure ·A.S. Dore, N.J. Robertson, James C. Errey, Irene W. Ng, Kaspar Hollenstein, B.G. Tehan, Edward Hurrell, K.A. Bennett, Miles Congreve, Francesca Magnani, Christopher G. Tate, Malcolm Weir, Fiona H. Marshall	2011	453
3	Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain Nature ·A.S. Dore, Krzysztof Okrasa, Jayesh C. Patel, María J. Serrano‐Vega, K.A. Bennett, Roger Cooke, James C. Errey, Ali Jazayeri, Samir Khan, B.G. Tehan, Malcolm Weir, Giselle R. Wiggin, Fiona H. Marshall	2014	324
4	Intracellular allosteric antagonism of the CCR9 receptor Nature ·Christine Oswald, Mathieu Rappas, James Kean, A.S. Dore, James C. Errey, K.A. Bennett, Francesca Deflorian, J.A. Christopher, Ali Jazayeri, Jonathan S. Mason, Miles Congreve, Roger Cooke, Fiona H. Marshall	2016	196
5	Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu ₅ Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile) Journal of Medicinal Chemistry ·J.A. Christopher, Sarah J. Aves, K.A. Bennett, A.S. Dore, James C. Errey, Ali Jazayeri, Fiona H. Marshall, Krzysztof Okrasa, María J. Serrano‐Vega, Benjamin G. Tehan, Giselle R. Wiggin, Miles Congreve	2015	122
6	Thermostabilisation of an Agonist-Bound Conformation of the Human Adenosine A2A Receptor Journal of Molecular Biology ·Guillaume Lebon, K.A. Bennett, Ali Jazayeri, Christopher G. Tate	2011	103
7	Pharmacology and Structure of Isolated Conformations of the Adenosine A2A Receptor Define Ligand Efficacy Molecular Pharmacology ·K.A. Bennett, Benjamin G. Tehan, Guillaume Lebon, Christopher G. Tate, Malcolm Weir, Fiona H. Marshall, Christopher J. Langmead	2013	58
8	When simple agonism is not enough: Emerging modalities of GPCR ligands Molecular and Cellular Endocrinology ·Nicola J. Smith, K.A. Bennett, Graeme Milligan	2010	56
9	Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis Journal of Medicinal Chemistry ·Mathieu Rappas, A. Ali, K.A. Bennett, Jason Brown, S.J. Bucknell, Miles Congreve, Roger Cooke, G. Cseke, Chris de Graaf, A.S. Dore, James C. Errey, Ali Jazayeri, Fiona H. Marshall, Jonathan Mason, Richard F. Mould, Jayesh C. Patel, Benjamin G. Tehan, Malcolm Weir, J.A. Christopher	2019	54
10	Growth Hormone Secretagogues and Growth Hormone Releasing Peptides Act As Orthosteric Super-Agonists but Not Allosteric Regulators for Activation of the G Protein Gαo1 by the Ghrelin Receptor Molecular Pharmacology ·K.A. Bennett, Christopher J. Langmead, Alan Wise, Graeme Milligan	2009	31
11	Structures of mGluRs shed light on the challenges of drug development of allosteric modulators Current Opinion in Pharmacology ·K.A. Bennett, A.S. Dore, J.A. Christopher, Dahlia R. Weiss, Fiona H. Marshall	2014	26
12	Targeting the Type 5 Metabotropic Glutamate Receptor: A Potential Therapeutic Strategy for Neurodegenerative Diseases? Frontiers in Pharmacology ·Rebecca F. Budgett, Geor Bakker, Eugenia Sergeev, K.A. Bennett, Sophie J. Bradley	2022	20
13	Discovery and Characterization of Novel Antagonists of the Proinflammatory Orphan Receptor GPR84 ACS Pharmacology & Translational Science ·Laura Jenkins, Sara Marsango, Sarah J. Mancini, Zobaer Al Mahmud, Angus J. Morrison, Stuart P. McElroy, K.A. Bennett, Matt Barnes, Andrew B. Tobin, Irina G. Tikhonova, Graeme Milligan	2021	16
14	Structure-based discovery and development of metabotropic glutamate receptor 5 negative allosteric modulators Advances in pharmacology ·K.A. Bennett, J.A. Christopher, Benjamin G. Tehan	2020	7
15	Characterisation of inverse agonism of the orphan-G protein-coupled receptor GPR52 by cannabinoid ligands Cannabidiol and O-1918 Heliyon ·Lisa A. Stott, Cheryl A. Brighton, Jason Brown, Richard F. Mould, K.A. Bennett, Robert G. Newman, Heather Currinn, Flavia Autore, Alícia P. Higueruelo, Benjamin G. Tehan, Cliona MacSweeney, Michael A. O’Brien, Steve P. Watson	2021	6
16	A novel somatostatin receptor ligand for human ACTH – and GH –secreting pituitary adenomas European Journal of Endocrinology ·Daniela Regazzo, Serena Avallone, Cliona MacSweeney, Eugenia Sergeev, David Howe, A. Godwood, K.A. Bennett, Alastair Brown, Matt Barnes, Gianluca Occhi, Mattia Barbot, Diego Faggian, Maria Pia Tropeano, Marco Losa, Giovanni Lasio, Carla Scaroni, Francesca Pecori Giraldi	2023	3
17	Understanding Exposure-Receptor Occupancy Relationships for Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators across a Range of Preclinical and Clinical Studies Journal of Pharmacology and Experimental Therapeutics ·K.A. Bennett, Eugenia Sergeev, Cliona MacSweeney, Geor Bakker, Anne Cooper	2021	3
18	Effect of HTL0045725, a selective agonist of the orphan receptor GPR52, on kinase and transcription factor phosphorylation in striatal neurons Neuroscience Applied ·Eugenia Sergeev, Lisa A. Stott, S.J. Bradley, K.A. Bennett, A.J.H. Brown, Stephen P. Watson, Geor Bakker, D.M. Leite, F. Cavallo, E.M. Rosethorne, T. Phillips, C.P. MacSweeney	2022	2

About K.A. Bennett

K.A. Bennett is a scholar working on Physiology, Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Molecular Biology and Neurology, having authored 18 papers that have together received 2.2k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (12 papers), Neuropeptides and Animal Physiology (7 papers), Adenosine and Purinergic Signaling (5 papers), Neuroscience and Neuropharmacology Research (5 papers), Chemical Synthesis and Analysis (4 papers), Immune Cell Function and Interaction (2 papers), Pharmacological Receptor Mechanisms and Effects (2 papers) and Circadian rhythm and melatonin (1 paper). The work is most often cited by research in Physiology (490 citations), Cellular and Molecular Neuroscience (1.1k citations), Molecular Biology (1.9k citations), Computational Theory and Mathematics (253 citations) and Radiology, Nuclear Medicine and Imaging (361 citations). K.A. Bennett has collaborated with scholars based in United Kingdom, Italy and United States. Frequent co-authors include Christopher G. Tate, Guillaume Lebon, Christopher J. Langmead, Fiona H. Marshall, Tony Warne, Patricia C. Edwards, Andrew G. W. Leslie, A.S. Dore, James C. Errey and Ali Jazayeri. Their work appears in journals such as Nature, Journal of Medicinal Chemistry, Molecular Pharmacology, ACS Pharmacology & Translational Science and European Journal of Endocrinology.

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