Bruce Beutler

83.6k citations
444 papers · 71.5k · 30 hit papers · h-index 117

Impact in

  • Immunology top 0.01%
    • Immune Response and Inflammation
    • Immune Cell Function and Interaction
    • interferon and immune responses
    • Immunotherapy and Immune Responses
    • T-cell and B-cell Immunology
  • Microbiology top 0.02%
    • Antimicrobial Peptides and Activities

Papers in

    • Immune Response and Inflammation 175
    • Immune Cell Function and Interaction 87
    • T-cell and B-cell Immunology 39
    • interferon and immune responses 37
    • Immunotherapy and Immune Responses 30
    • Antimicrobial Peptides and Activities 32

Bruce Beutler

433 papers receiving 68.4k citations

Bruce Beutler's Hit Papers

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component 2015 · 645 citations
6450+12+24Years since publication2.0k4.0k6.0k

Peers

Bruce Beutler
Comparison fields: 5 of 190
  • Immunology 39.5k
  • Microbiology 4.4k
  • Cancer Research 5.9k
  • Epidemiology 11.0k
  • Immunology and Allergy 1.8k
Replace Ruslan M. Medzhitov with:
Ruslan M. Medzhitov United States
Kiyoshi Takeda Japan
Douglas Taylor Golenbock United States
Siamon Gordon United Kingdom
Gabriel Núñez United States
Carl Nathan United States
Taro Kawai Japan
Osamu Takeuchi Japan
Luke A.J. O'Neill Ireland
Charles A. Janeway United States
Bruce Beutler relative to Ruslan M. Medzhitov United States Ruslan M. Medzhitov's profile →
Citations per field
00.5×1.5×
Ruslan M. Medzhitov · 1×
Citations per year

Countries citing papers authored by Bruce Beutler

Since Specialization
Citations

This map shows the geographic impact of Bruce Beutler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce Beutler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce Beutler more than expected).

Fields of papers citing papers by Bruce Beutler

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce Beutler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce Beutler. The network helps show where Bruce Beutler may publish in the future.

Co-authors

The 25 scholars most cited alongside Bruce Beutler, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bruce Beutler Line = papers co-authored together Bruce Beutler links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 444 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
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19986644
2
Shock and Tissue Injury Induced by Recombinant Human Cachectin
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19862288
3
Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin
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19852105
4
The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response
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19891525
5
Cachectin and tumour necrosis factor as two sides of the same biological coin
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19861487
6
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.
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19861418
7
Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.
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19861345
8
Cachectin: More Than a Tumor Necrosis Factor
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19871309
9
Inferences, questions and possibilities in Toll-like receptor signalling
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20041248
10
Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance
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19861166
11
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.
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19851128
12
Innate immune sensing and its roots: the story of endotoxin
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20031117
13
Intracellular Toll-like Receptors
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20101082
14
The Tumor Necrosis Factor Ligand and Receptor Families
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19961075
15
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
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20031074
16
TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY
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20041029
17
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
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2006972
18
Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
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1985965
19
Innate immunity: an overview
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2003961
20
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
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2005939

About Bruce Beutler

Bruce Beutler is a scholar working on Immunology, Microbiology, Molecular Biology, Cancer Research and Epidemiology, having authored 444 papers that have together received 71.5k indexed citations. Recurring topics across this work include Immune Response and Inflammation (175 papers), Immune Cell Function and Interaction (87 papers), T-cell and B-cell Immunology (39 papers), interferon and immune responses (37 papers), Antimicrobial Peptides and Activities (32 papers), NF-κB Signaling Pathways (30 papers), Immunotherapy and Immune Responses (30 papers) and Adipokines, Inflammation, and Metabolic Diseases (20 papers). The work is most often cited by research in Immunology (39.5k citations), Microbiology (4.4k citations), Cancer Research (5.9k citations), Epidemiology (11.0k citations) and Immunology and Allergy (1.8k citations). Bruce Beutler has collaborated with scholars based in United States, France and Germany. Frequent co-authors include Anthony Cerami, Xin Du, Kasper H. N. Hoebe, Alexander N. Poltorak, Christophe Van Huffel, Flavia Bazzoni, Irina Smirnova, Amanda L. Blasius, Paola Ricciardi‐Castagnoli and Marina A. Freudenberg. Their work appears in journals such as Proceedings of the National Academy of Sciences, The Journal of Experimental Medicine, The Journal of Immunology, Science and Nature Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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