Siegfried Hapfelmeier

10.8k total citations · 6 hit papers
49 papers, 7.7k citations indexed

About

Siegfried Hapfelmeier is a scholar working on Molecular Biology, Food Science and Immunology. According to data from OpenAlex, Siegfried Hapfelmeier has authored 49 papers receiving a total of 7.7k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Molecular Biology, 14 papers in Food Science and 13 papers in Immunology. Recurrent topics in Siegfried Hapfelmeier's work include Gut microbiota and health (24 papers), Escherichia coli research studies (12 papers) and Salmonella and Campylobacter epidemiology (8 papers). Siegfried Hapfelmeier is often cited by papers focused on Gut microbiota and health (24 papers), Escherichia coli research studies (12 papers) and Salmonella and Campylobacter epidemiology (8 papers). Siegfried Hapfelmeier collaborates with scholars based in Switzerland, Germany and Canada. Siegfried Hapfelmeier's co-authors include Wolf‐Dietrich Hardt, Andrew J. Macpherson, Kathy D. McCoy, Marcus Kremer, Emma Slack, Bärbel Stecher, Markus B. Geuking, Melissa A. Lawson, Mathias Heikenwälder and Manja Barthel and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Siegfried Hapfelmeier

49 papers receiving 7.7k citations

Hit Papers

The maternal microbiota drives early ... 2003 2026 2010 2018 2016 2003 2011 2010 2015 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The maternal microbiota drives early postnatal innate immune development
    2016 860 citations Mercedes Gomez de Agüero, Stephanie C. Ganal‐Vonarburg et al. Science profile →
  2. Pretreatment of Mice with Streptomycin Provides aSalmonella entericaSerovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host
    2003 809 citations Manja Barthel, Siegfried Hapfelmeier et al. profile →
  3. Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses
    2011 648 citations Markus B. Geuking, Julia Cahenzli et al. Immunity profile →
  4. Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses
    2010 598 citations Siegfried Hapfelmeier, Melissa A. Lawson et al. Science profile →
  5. Gut Microbiota Orchestrates Energy Homeostasis during Cold
    2015 596 citations Siegfried Hapfelmeier et al. profile →
  6. Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
    2009 383 citations Emma Slack, Siegfried Hapfelmeier et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Siegfried Hapfelmeier Switzerland 31 4.0k 2.0k 1.8k 1.7k 1.1k 49 7.7k
Beth A. McCormick United States 52 3.5k 0.9× 1.7k 0.9× 2.7k 1.5× 2.0k 1.2× 1.9k 1.7× 148 9.3k
Manuela Raffatellu United States 44 3.0k 0.7× 1.8k 0.9× 1.6k 0.9× 2.5k 1.5× 1.5k 1.3× 81 7.6k
Emma Allen‐Vercoe Canada 42 5.8k 1.5× 2.5k 1.2× 1.6k 0.9× 1.5k 0.9× 421 0.4× 143 10.3k
Inna Sekirov Canada 17 4.1k 1.0× 2.2k 1.1× 599 0.3× 1.2k 0.7× 670 0.6× 52 6.6k
Nita H. Salzman United States 43 4.7k 1.2× 1.5k 0.8× 2.5k 1.4× 1.5k 0.8× 370 0.3× 97 9.2k
Mariana X. Byndloss United States 32 3.9k 1.0× 1.4k 0.7× 640 0.4× 1.3k 0.8× 545 0.5× 55 5.9k
Emma Slack Switzerland 40 3.3k 0.8× 1.8k 0.9× 3.5k 1.9× 801 0.5× 528 0.5× 70 8.0k
Blaise Corthésy Switzerland 47 3.3k 0.8× 1.5k 0.7× 3.2k 1.8× 833 0.5× 635 0.6× 124 8.4k
Mathias W. Hornef Germany 53 3.7k 0.9× 1.9k 0.9× 2.7k 1.5× 832 0.5× 518 0.5× 142 9.2k
Bärbel Stecher Germany 51 7.8k 1.9× 3.2k 1.6× 1.4k 0.8× 3.3k 1.9× 2.0k 1.8× 102 13.2k

Countries citing papers authored by Siegfried Hapfelmeier

Since Specialization
Citations

This map shows the geographic impact of Siegfried Hapfelmeier's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Siegfried Hapfelmeier with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Siegfried Hapfelmeier more than expected).

Fields of papers citing papers by Siegfried Hapfelmeier

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Siegfried Hapfelmeier. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Siegfried Hapfelmeier. The network helps show where Siegfried Hapfelmeier may publish in the future.

Co-authorship network of co-authors of Siegfried Hapfelmeier

This figure shows the co-authorship network connecting the top 25 collaborators of Siegfried Hapfelmeier. A scholar is included among the top collaborators of Siegfried Hapfelmeier based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Siegfried Hapfelmeier. Siegfried Hapfelmeier is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Jalil, Antoine, Alessia Perino, Yuan Dong, et al.. (2025). Bile acid 7α-dehydroxylating bacteria accelerate injury-induced mucosal healing in the colon. EMBO Molecular Medicine. 17(5). 889–908. 5 indexed citations
2.
Philip, Vivek M., Hailong Zhang, Jun Lü, et al.. (2025). Innate immune system signaling and intestinal dendritic cells migration to the brain underlie behavioral changes after microbial colonization in adult mice. Brain Behavior and Immunity. 127. 238–250. 4 indexed citations
3.
Artola-Borán, Mariela, Peter Leary, Mine Durusu Tanrıöver, et al.. (2024). IgA facilitates the persistence of the mucosal pathogen Helicobacter pylori. Mucosal Immunology. 18(1). 232–247. 1 indexed citations
4.
Mateo, Pierre, Tobias Züst, Valentin Gfeller, et al.. (2024). The lactonase BxdA mediates metabolic specialisation of maize root bacteria to benzoxazinoids. Nature Communications. 15(1). 6535–6535. 19 indexed citations
5.
Dong, Yuan, et al.. (2024). Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid. BMC Microbiology. 24(1). 286–286. 8 indexed citations
6.
Philip, Vivek M., Giada De Palma, Elena F. Verdú, et al.. (2023). A8 MICROBIAL ACTIVATION OF INTESTINAL DENDRITIC CELLS IS CRITICAL FOR THE ESTABLISHMENT OF NORMAL BEHAVIOR. Journal of the Canadian Association of Gastroenterology. 6(Supplement_1). 4–5. 1 indexed citations
7.
Hapfelmeier, Siegfried, Markus M. Heimesaat, Stefan Bereswill, et al.. (2023). Mouse models for bacterial enteropathogen infections: insights into the role of colonization resistance. Gut Microbes. 15(1). 2172667–2172667. 34 indexed citations
8.
Hapfelmeier, Siegfried, et al.. (2022). The stationary phase-specific sRNA FimR2 is a multifunctional regulator of bacterial motility, biofilm formation and virulence. Nucleic Acids Research. 50(20). 11858–11875. 14 indexed citations
9.
Yildiz, Soner, Matthieu Bergé, Víctor González‐Ruiz, et al.. (2020). Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization. eLife. 9. 27 indexed citations
10.
Dong, Yuan, Suresh Poudel, Laure Menin, et al.. (2020). Biogeography of microbial bile acid transformations along the murine gut. Journal of Lipid Research. 61(11). 1450–1463. 65 indexed citations
11.
Li, Hai, Julien Limenitakis, Victor Greiff, et al.. (2020). Mucosal or systemic microbiota exposures shape the B cell repertoire. Nature. 584(7820). 274–278. 138 indexed citations
12.
Menin, Laure, et al.. (2018). In vitro and in vivo characterization of Clostridium scindens bile acid transformations. Gut Microbes. 10(4). 481–503. 90 indexed citations
13.
Uchimura, Yasuhiro, Tobias Fuhrer, Hai Li, et al.. (2018). Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response. Immunity. 49(3). 545–559.e5. 115 indexed citations
14.
Agüero, Mercedes Gomez de, Stephanie C. Ganal‐Vonarburg, Tobias Fuhrer, et al.. (2016). The maternal microbiota drives early postnatal innate immune development. Science. 351(6279). 1296–1302. 860 indexed citations breakdown →
15.
Slack, Emma, Maria L. Balmer, Jörg H. Fritz, & Siegfried Hapfelmeier. (2012). Functional Flexibility of Intestinal IgA – Broadening the Fine Line. Frontiers in Immunology. 3. 100–100. 80 indexed citations
16.
Geuking, Markus B., Julia Cahenzli, Melissa A. Lawson, et al.. (2011). Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses. Immunity. 34(5). 794–806. 648 indexed citations breakdown →
17.
Hapfelmeier, Siegfried, Melissa A. Lawson, Emma Slack, et al.. (2010). Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses. Science. 328(5986). 1705–1709. 598 indexed citations breakdown →
18.
Slack, Emma, Siegfried Hapfelmeier, Bärbel Stecher, et al.. (2009). Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism. Science. 325(5940). 617–620. 383 indexed citations breakdown →
19.
Hapfelmeier, Siegfried, Bärbel Stecher, Manja Barthel, et al.. (2005). The Salmonella Pathogenicity Island (SPI)-2 and SPI-1 Type III Secretion Systems Allow Salmonella Serovar typhimurium to Trigger Colitis via MyD88-Dependent and MyD88-Independent Mechanisms. The Journal of Immunology. 174(3). 1675–1685. 311 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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