Giorgio Trinchieri

94.1k total citations · 29 hit papers
434 papers, 67.5k citations indexed

About

Giorgio Trinchieri is a scholar working on Immunology, Molecular Biology and Oncology. According to data from OpenAlex, Giorgio Trinchieri has authored 434 papers receiving a total of 67.5k indexed citations (citations by other indexed papers that have themselves been cited), including 319 papers in Immunology, 93 papers in Molecular Biology and 81 papers in Oncology. Recurrent topics in Giorgio Trinchieri's work include Immune Cell Function and Interaction (195 papers), T-cell and B-cell Immunology (104 papers) and Immunotherapy and Immune Responses (93 papers). Giorgio Trinchieri is often cited by papers focused on Immune Cell Function and Interaction (195 papers), T-cell and B-cell Immunology (104 papers) and Immunotherapy and Immune Responses (93 papers). Giorgio Trinchieri collaborates with scholars based in United States, Italy and France. Giorgio Trinchieri's co-authors include B Perussia, Maria Wysocka, Alan Sher, D Santoli, Marek Kubin, Phillip Scott, Miguel Aste-Amézaga, Franca Gerosa, Xiaojing Ma and Carine Asselin‐Paturel and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Giorgio Trinchieri

429 papers receiving 65.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Interleukin-12 and the regulation of innate resistance and adaptive immunity

2003 3.1k citations Giorgio Trinchieri profile →
Biology of Natural Killer Cells

1989 2.5k citations Giorgio Trinchieri profile →
Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity

1995 2.1k citations Giorgio Trinchieri profile →
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.

1989 1.7k citations Giorgio Trinchieri et al. The Journal of Experimental Medicine profile →
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

1993 1.4k citations Giorgio Trinchieri et al. The Journal of Experimental Medicine profile →
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

1995 1.3k citations Giorgio Trinchieri et al. The Journal of Immunology profile →
Plasmacytoid dendritic cells in immunity

2004 1.3k citations Giorgio Trinchieri et al. profile →
Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.

1993 1.2k citations Marek Kubin, Giorgio Trinchieri et al. The Journal of Experimental Medicine profile →
Cooperation of Toll-like receptor signals in innate immune defence

2007 1.1k citations Giorgio Trinchieri et al. profile →
Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

1994 925 citations Giorgio Trinchieri profile →
Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.

1991 858 citations Howard A. Young, Giorgio Trinchieri et al. The Journal of Experimental Medicine profile →
Reciprocal Activating Interaction between Natural Killer Cells and Dendritic Cells

2002 829 citations Giorgio Trinchieri et al. The Journal of Experimental Medicine profile →
Compartmentalized Control of Skin Immunity by Resident Commensals

2012 820 citations Shruti Naik, Nicolas Bouladoux et al. Science profile →
Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

2001 814 citations Alain Vicari, Giorgio Trinchieri et al. profile →
In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α

1996 760 citations Giorgio Trinchieri et al. The Journal of Immunology profile →
The IL-12 Family of Heterodimeric Cytokines

2003 745 citations Giorgio Trinchieri et al. profile →
Microbiota: a key orchestrator of cancer therapy

2017 677 citations Giorgio Trinchieri et al. profile →
Type I interferon: friend or foe?

2010 667 citations Giorgio Trinchieri The Journal of Experimental Medicine profile →
The Adjuvant Effect of Interleukin-12 in a Vaccine Against Leishmania major

1994 603 citations Giorgio Trinchieri et al. Science profile →
Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and antagonistic inhibition of susceptibility of target cells to lysis.

1978 590 citations Giorgio Trinchieri, D Santoli The Journal of Experimental Medicine profile →
Parasite-induced IL-12 stimulates early IFN- gamma synthesis and resistance during acute infection with Toxoplasma gondii .

1994 588 citations Giorgio Trinchieri et al. The Journal of Immunology profile →
Immune interferon: a pleiotropic lymphokine with multiple effects

1985 583 citations Giorgio Trinchieri et al. profile →
The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells.

1996 574 citations Giorgio Trinchieri et al. The Journal of Experimental Medicine profile →
Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance

2017 571 citations Jonathan H. Badger, Giorgio Trinchieri et al. profile →
Interleukin-12 in anti-tumor immunity and immunotherapy

2002 567 citations Mario P. Colombo, Giorgio Trinchieri profile →
Response of resting human peripheral blood natural killer cells to interleukin 2.

1984 539 citations Giorgio Trinchieri et al. The Journal of Experimental Medicine profile →
Human dermal mast cells contain and release tumor necrosis factor alpha, which induces endothelial leukocyte adhesion molecule 1.

1991 519 citations Giorgio Trinchieri et al. profile →
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts

2006 506 citations Giorgio Trinchieri et al. profile →
Targeting the gut microbiota for cancer therapy

2022 181 citations Giorgio Trinchieri et al. profile →

Peers

Countries citing papers authored by Giorgio Trinchieri

Since Specialization

Citations

This map shows the geographic impact of Giorgio Trinchieri's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Giorgio Trinchieri with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Giorgio Trinchieri more than expected).

Fields of papers citing papers by Giorgio Trinchieri

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Giorgio Trinchieri. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Giorgio Trinchieri. The network helps show where Giorgio Trinchieri may publish in the future.

Co-authorship network of co-authors of Giorgio Trinchieri

This figure shows the co-authorship network connecting the top 25 collaborators of Giorgio Trinchieri. A scholar is included among the top collaborators of Giorgio Trinchieri based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Giorgio Trinchieri. Giorgio Trinchieri is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Microbiota and adipocyte mitochondrial damage in type 2 diabetes are linked by Mmp12+ macrophages 2022 ·The Journal of Experimental Medicine ·Zhipeng Li, Manoj Gurung, Richard R. Rodrigues, Jyothi Padiadpu, Nolan K. Newman, Nathan P. Manes, (unknown), Renee L. Greer, Stephany Vasquez‐Perez, (unknown), (unknown), (unknown), (unknown), Dominic De Nardo, Amiran Dzutsev, Aleksandra Nita‐Lazar, Giorgio Trinchieri, Natalia Shulzhenko, Andrey Morgun	38
2	The systemic anti-microbiota IgG repertoire can identify gut bacteria that translocate across gut barrier surfaces 2022 ·Science Translational Medicine ·Ivan Vujkovic-Cvijin, Hugh C. Welles, Connie Ha, (unknown), Shreni Mistry, Jason M. Brenchley, Giorgio Trinchieri, Suzanne Devkota, Yasmine Belkaid	43
3	The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019 2020 ·Journal for ImmunoTherapy of Cancer ·Paolo A. Ascierto, Carlo Bifulco, (unknown), Claus Garbe, Samir N. Khleif, Jennifer L. McQuade, Kunle Odunsi, Hideho Okada, Chrystal M. Paulos, Sergio A. Quezada, Hussein A. Tawbi, John M. Timmerman, Giorgio Trinchieri, Lisa H. Butterfield, Igor Puzanov	2
4	The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance 2018 ·The Journal of Immunology ·Teizo Yoshimura, Mairi H McLean, Amiran Dzutsev, Xiaohong Yao, Keqiang Chen, Jiaqiang Huang, Wanghua Gong, Jiamin Zhou, Yi Xiang, Jonathan H. Badger, Colm Ó’hUigín, Vishal Thovarai, Lino Tessarollo, Scott K. Durum, Giorgio Trinchieri, Xiu‐Wu Bian, Jiming Wang	62
5	Cutting Edge: Quantitative Determination of CD40L Threshold for IL-12 and IL-23 Production from Dendritic Cells 2018 ·The Journal of Immunology ·Kaveh Abdi, Karen Laky, Kartika Padhan, Constantinos Petrovas, Jeff Skinner, Juraj Kabát, David W. Dorward, Joseph Brzostowski, Eric O. Long, Giorgio Trinchieri, Rajat Varma	10
6	NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay 2015 ·Cancer Research ·Lisa A. Ridnour, Robert Y.S. Cheng, Jonathan M. Weiss, Sukhbir Kaur, David R. Soto‐Pantoja, Debashree Basudhar, Julie L. Heinecke, Charles A. Stewart, William DeGraff, Anastasia L. Sowers, Angela Thetford, Aparna H. Kesarwala, David D. Roberts, Howard A. Young, James B. Mitchell, Giorgio Trinchieri, Robert H. Wiltrout, David A. Wink	35
7	Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells 2015 ·Cancer Research ·Monica Bodogai, Kanako Moritoh, Catalina Lee-Chang, Christine Hollander, Cheryl A. Sherman‐Baust, Robert P. Wersto, Yoshihiko Araki, Ichiro Miyoshi, Yang Li, Giorgio Trinchieri, Arya Biragyn	122
8	TGF-β Signaling in Myeloid Cells Is Required for Tumor Metastasis 2013 ·Cancer Discovery ·Yanli Pang, Sudheer Kumar Gara, Bhagelu R. Achyut, Zhaoyang Li, Hannah H. Yan, Chi‐Ping Day, Jonathan M. Weiss, Giorgio Trinchieri, John C. Morris, Yang Li	129
9	Compartmentalized Control of Skin Immunity by Resident Commensals breakdown → 2012 ·Science ·Shruti Naik, Nicolas Bouladoux, Christoph Wilhelm, Michael J. Molloy, Rosalba Salcedo, Wolfgang Kastenmüller, Clayton Deming, Mariam Quiñones, Lily Y. Koo, Sean Conlan, Sean P. Spencer, Jason A. Hall, Amiran Dzutsev, Heidi H. Kong, Daniel Campbell, Giorgio Trinchieri, Julia A. Segre, Yasmine Belkaid	820
10	The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma 2012 ·Cancer Research ·Juan Wu, Jiaqi Li, Rosalba Salcedo, Nahid F. Mivechi, Giorgio Trinchieri, Anatolij Horuzsko	194
11	Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis 2010 ·Cancer Research ·Sabina Sangaletti, Claudio Tripodo, Chiara Ratti, Silvia Piconese, Rossana Porcasi, Rosalba Salcedo, Giorgio Trinchieri, Mario P. Colombo, Claudia Chiodoni	31
12	Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts 2010 ·Cancer Research ·Sid P. Kerkar, Pawel Muranski, Andrew Kaiser, Andrea Boni, Luis Sánchez-Pérez, Zhiya Yu, Douglas C. Palmer, Robert Reger, Zachary A. Borman, Ling Zhang, Richard A. Morgan, Luca Gattinoni, Steven A. Rosenberg, Giorgio Trinchieri, Nicholas P. Restifo	207
13	MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18 2010 ·The Journal of Experimental Medicine ·Rosalba Salcedo, Andrea Worschech, Marco Cardone, Yava Jones‐Hall, (unknown), Ren‐Ming Dai, Ena Wang, (unknown), Diana C. Haines, Colm Ó’hUigín, Francesco M. Marincola, Giorgio Trinchieri	358
14	A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells 2005 ·The Journal of Experimental Medicine ·Grégory Gautier, Martine Humbert, Florence Deauvieau, (unknown), John Hiscott, Elizabeth E. M. Bates, Giorgio Trinchieri, Christophe Caux, Pierre Garrone	429
15	Redirecting In vivo Elicited Tumor Infiltrating Macrophages and Dendritic Cells towards Tumor Rejection 2005 ·Cancer Research ·Cristiana Guiducci, Alain Vicari, Sabina Sangaletti, Giorgio Trinchieri, Mario P. Colombo	436
16	Association between HIV-specific T helper responses and CTL activities in pediatric AIDS 2000 ·European Journal of Immunology ·(unknown), Andrzej Wierzbicki, Valerie E. Whiteman, Giorgio Trinchieri, Harold W. Lischner, Danuta Kozbor	26
17	Association between HIV-specific T helper responses and CTL activities in pediatric AIDS 2000 ·European Journal of Immunology ·(unknown), Andrzej Wierzbicki, Valerie E. Whiteman, Giorgio Trinchieri, Harold W. Lischner, Danuta Kozbor	4
18	Detection of the production of interleukin (IL) 12 by human keratinocytes 1994 ·Journal of Investigative Dermatology ·Yoshinori Aragane, Helge Riemann, Ranjit Bhardwaj, Agatha Schwarz, Thomas A. Luger, Marek Kubin, Giorgio Trinchieri, Thomas Schwarz	2
19	Spontaneous cell-mediated cytotoxicity in humans. Distribution and characterization of the effector cell. 1978 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·D Santoli, Giorgio Trinchieri, Lorenzo Moretta, Chester M. Zmijewski, Hilary Koprowski	53
20	Cell-mediated cytotoxicity against virus-infected target cells in humans. I. Characterization of the effector lymphocyte. 1978 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·D Santoli, Giorgio Trinchieri, Florence S. Lief	105

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