Marina A. Freudenberg

26.2k total citations · 5 hit papers
170 papers, 20.9k citations indexed

About

Marina A. Freudenberg is a scholar working on Immunology, Molecular Biology and Epidemiology. According to data from OpenAlex, Marina A. Freudenberg has authored 170 papers receiving a total of 20.9k indexed citations (citations by other indexed papers that have themselves been cited), including 122 papers in Immunology, 39 papers in Molecular Biology and 22 papers in Epidemiology. Recurrent topics in Marina A. Freudenberg's work include Immune Response and Inflammation (106 papers), Immune Cell Function and Interaction (29 papers) and Immunotherapy and Immune Responses (17 papers). Marina A. Freudenberg is often cited by papers focused on Immune Response and Inflammation (106 papers), Immune Cell Function and Interaction (29 papers) and Immunotherapy and Immune Responses (17 papers). Marina A. Freudenberg collaborates with scholars based in Germany, United States and Switzerland. Marina A. Freudenberg's co-authors include Chris Galanos, Bruce Beutler, Xin Du, Alexander Poltorak, Irina Smirnova, Erica Alejos, Paola Ricciardi‐Castagnoli, Christophe Van Huffel, Maria João Silva and Xiaolong He and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Marina A. Freudenberg

170 papers receiving 20.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 6.3k citations Alexander Poltorak, Irina Smirnova et al. profile →
Impaired immune and acute-phase responses in interleukin-6-deficient mice

1994 1.5k citations Marina A. Freudenberg et al. Nature profile →
Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

2002 1.1k citations Christian Termeer, Frauke Benedix et al. The Journal of Experimental Medicine profile →
Galactosamine-induced sensitization to the lethal effects of endotoxin.

1979 836 citations Chris Galanos, Marina A. Freudenberg et al. Proceedings of the National Academy of Sciences profile →
CD14 is required for MyD88-independent LPS signaling

2005 534 citations Christoph Kalis, Simone Keck et al. profile →

Peers

Countries citing papers authored by Marina A. Freudenberg

Since Specialization

Citations

This map shows the geographic impact of Marina A. Freudenberg's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marina A. Freudenberg with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marina A. Freudenberg more than expected).

Fields of papers citing papers by Marina A. Freudenberg

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marina A. Freudenberg. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marina A. Freudenberg. The network helps show where Marina A. Freudenberg may publish in the future.

Co-authorship network of co-authors of Marina A. Freudenberg

This figure shows the co-authorship network connecting the top 25 collaborators of Marina A. Freudenberg. A scholar is included among the top collaborators of Marina A. Freudenberg based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Marina A. Freudenberg. Marina A. Freudenberg is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Sulfatides are endogenous ligands for the TLR4–MD-2 complex 2021 ·Proceedings of the National Academy of Sciences ·Lijing Su, Muhammad Athamna, Ying Wang, Junmei Wang, Marina A. Freudenberg, Tao Yue, Jianhui Wang, Eva Marie Y. Moresco, (unknown), Tsaffrir Zor, Bruce Beutler	40
2	Lung macrophage scavenger receptor SR-A6 (MARCO) is an adenovirus type-specific virus entry receptor 2018 ·PLoS Pathogens ·(unknown), Maarit Suomalainen, Justin W. Flatt, Markus Schmid, Martin Pačesa, Silvio Hemmi, Wolfgang Jungraithmayr, (unknown), Marina A. Freudenberg, Andreas Plückthun, Tobias May, Mario Köster, György Fejér, Urs F. Greber	57
3	Nontransformed, GM-CSF–dependent macrophage lines are a unique model to study tissue macrophage functions 2013 ·Proceedings of the National Academy of Sciences ·György Fejér, (unknown), Ildikó Győry, Idan Cohen, Peggy Engelhard, Elena Voronov, Thomas Manke, Zsolt Ruzsics, Lars Dölken, Olivia Prazeres da Costa, Nora Branzk, Michael Huber, Antje Prasse, Robert C. Schneider, Ron N. Apte, Chris Galanos, Marina A. Freudenberg	82
4	Activation of Murine Macrophages via TLR2 and TLR4 Is Negatively Regulated by a Lyn/PI3K Module and Promoted by SHIP1 2010 ·The Journal of Immunology ·Simone Keck, Marina A. Freudenberg, Michael Huber	65
5	TLR4-induced IFN-γ production increases TLR2 sensitivity and drives Gram-negative sepsis in mice 2008 ·The Journal of Experimental Medicine ·(unknown), Greg Elson, Ruth Ferstl, Stefan Dreher, Thomas Mueller, Marina A. Freudenberg, Bruno Daubeuf, Hermann Wagner, Carsten J. Kirschning	100
6	Key Role of Splenic Myeloid DCs in the IFN-αβ Response to Adenoviruses In Vivo 2008 ·PLoS Pathogens ·György Fejér, (unknown), Jan Liese, Ulrike Schleicher, Zsolt Ruzsics, (unknown), Urs F. Greber, Simone Keck, Bernd Hildenbrand, Anne Krug, Christian Bogdan, Marina A. Freudenberg	132
7	TLR4 Up-Regulation at Protein or Gene Level Is Pathogenic for Lupus-Like Autoimmune Disease 2006 ·The Journal of Immunology ·Bei Liu, Yi Yang, Jie Dai, Ruslan Medzhitov, Marina A. Freudenberg, Ping L. Zhang, Zihai Li	117
8	Stage of primary infection with lymphocytic choriomeningitis virus determines predisposition or resistance of mice to secondary bacterial infections 2006 ·Medical Microbiology and Immunology ·Marina Gumenscheimer, Sandra Balkow, Markus M. Simon, Emilio Jirillo, Chris Galanos, Marina A. Freudenberg	9
9	Stimulation of mast cells via FcɛR1 and TLR2: The type of ligand determines the outcome 2006 ·Molecular Immunology ·(unknown), Fillip Port, (unknown), Christoph Kalis, Wolfgang G. Bessler, Chris Galanos, Gerald Krystal, Marina A. Freudenberg, Michael Huber	33
10	Requirement for TLR9 in the Immunomodulatory Activity of Propionibacterium acnes 2005 ·The Journal of Immunology ·Christoph Kalis, Marina Gumenscheimer, Nikolaus Freudenberg, Sandrine Tchaptchet, György Fejér, Antje Heit, Shizuo Akira, Chris Galanos, Marina A. Freudenberg	94
11	Influence of EDTA and heparin on lipopolysaccharide binding and cell activation, evaluated at single‐cell level in whole blood 2002 ·Cytometry ·Milena Karina Coló Brunialti, Esper G. Kallás, Marina A. Freudenberg, Chris Galanos, Reinaldo Salomão	27
12	Expression and role of CD14 in mice sensitized to lipopolysaccharide by Propionibacterium acnes 2002 ·European Journal of Immunology ·Thomas Merlin, (unknown), Colleen Fearns, Marina A. Freudenberg, Régine Landmann	16
13	Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4 breakdown → 2002 ·The Journal of Experimental Medicine ·Christian Termeer, Frauke Benedix, Jonathan P. Sleeman, Christina Fieber, Ursula Voith, Thomas Ahrens, Kensuke Miyake, Marina A. Freudenberg, C. Galanos, Jan C. Simon	1121
14	A Point Mutation in the IL-12R β2 Gene Underlies the IL-12 Unresponsiveness of Lps- Defective C57BL/10ScCr Mice 2001 ·The Journal of Immunology ·Alexander Poltorak, Thomas Merlin, Peter Nielsen, Olivier Sandra, Irina Smirnova, Ingo Schupp, Thomas Boehm, Chris Galanos, Marina A. Freudenberg	62
15	Defective LPS signaling in C3 H/HeJ and C57 BL/10 ScCr mice: Mutations in Tlr4 Gene 1999 ·Pneumologie ·Alexander Poltorak, (unknown), Irina Smirnova, (unknown), Christophe Van Huffel, Xing Du, (unknown), Erica Alejos, Mariana Suvá, C. Galanos, Marina A. Freudenberg, Paola Ricciardi‐Castagnoli, (unknown), Bruce Beutler	257
16	Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection 1997 ·Nature ·Robert Smail Jack, Xiaolong Fan, Martin Bernheiden, Gabriele M. Rune, Monika Ehlers, A. Weber, G. Kirsch, R Mentel, B Fürll, Marina A. Freudenberg, Gerd Schmitz, Felix Stelter, Christine Schütt	284
17	Lipopolysaccharide ofRhodospirillum salinarum 40: structural studies on the core and lipid A region 1995 ·Archives of Microbiology ·(unknown), Ulrich Seydel, Marina A. Freudenberg, J. Weckesser, Hubert Mayer	12
18	[The role of cytokines in endotoxic shock and in endotoxin hypersensitivity]. 1993 ·PubMed ·Marina A. Freudenberg, Traci L. Ness, Yoshio Kumazawa, Chris Galanos	9
19	Bacterial endotoxins: biological properties and mechanisms of action 1993 ·Mediators of Inflammation ·C. Galanos, Marina A. Freudenberg	39
20	Immunoblot Analysis of the R-form Lipopolysaccharide from Salmonella S forms 1992 ·Zentralblatt für Bakteriologie ·S Schlecht, Marina A. Freudenberg, Chris Galanos	6

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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