Yichin Liu

5.8k citations

33 papers · 2.3k indexed · 1 hit paper · h-index 21

Molecular Biology top 5%
Oncology top 10%
Physiology top 5%
Neurology top 5%
Radiology, Nuclear Medicine and Imaging top 5%

Co-authors: Peter T. Lansbury Hilal A. Lashuel Zhihua Liu Lara Fallon John D. McCarter Ryan J. Watts Weiru Wang Jasvinder K. Atwal
Topics: Monoclonal and Polyclonal Antibodies Research (6 papers)Mass Spectrometry Techniques and Applications (5 papers)HER2/EGFR in Cancer Research (4 papers)
Cited by: Biological Psychiatry Neurology Molecular Biology
Journals: Cell Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States France United Kingdom

In The Last Decade

Yichin Liu

33 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The UCH-L1 Gene Encodes Two Opposing Enzymatic Activities that Affect α-Synuclein Degradation and Parkinson's Disease Susceptibility

2002 652 citations Yichin Liu, Lara Fallon et al. Cell profile →

Peers

Countries citing papers authored by Yichin Liu

Since Specialization

Citations

This map shows the geographic impact of Yichin Liu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yichin Liu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yichin Liu more than expected).

Fields of papers citing papers by Yichin Liu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yichin Liu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yichin Liu. The network helps show where Yichin Liu may publish in the future.

Co-authorship network of co-authors of Yichin Liu

This figure shows the co-authorship network connecting the top 25 collaborators of Yichin Liu. A scholar is included among the top collaborators of Yichin Liu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yichin Liu. Yichin Liu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Improved translation of stability for conjugated antibodies using an in vitro whole blood assay 2020 ·mAbs ·Aimee Fourie-O’Donohue,(unknown),Josefa Chuh,(unknown),Siao Ping Tsai,John C. Tran,William S. Sawyer,Dian Su,Carl Ng,Keyang Xu,Shang‐Fan Yu,Thomas H. Pillow,Jack Sadowsky,Peter S. Dragovich,Yichin Liu,Katherine R. Kozak	8
2	Catalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug Conjugates 2019 ·Drug Metabolism and Disposition ·Donglu Zhang,Aimee Fourie-O’Donohue,Peter S. Dragovich,Thomas H. Pillow,Jack Sadowsky,Katherine R. Kozak,Robert Cass,Liling Liu,Yuzhong Deng,Yichin Liu,Cornelis E. C. A. Hop,S. Cyrus Khojasteh	36
3	Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2) 2018 ·ACS Medicinal Chemistry Letters ·Zhonghua Pei,Rohan Mendonca,Lewis Gazzard,Richard Pastor,(unknown),Amy Gustafson,Erica C. VanderPorten,Georgia Hatzivassiliou,Kevin DeMent,Robert Cass,Po‐wai Yuen,Yamin Zhang,Guosheng Wu,Xingyu Lin,Yichin Liu,Benjamin D. Sellers	34
4	Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody–Drug Conjugates 2017 ·Cancer Research ·(unknown),Josefa Chuh,Yong Ma,Donglu Zhang,Katherine R. Kozak,Yichin Liu,Thomas H. Pillow,Jack Sadowsky,Tommy K. Cheung,Qui Phung,Benjamin Haley,(unknown),Robert W. Akita,Mark X. Sliwkowski,Andrew G. Polson	98
5	Identification of Small-Molecule Noncovalent Binders Utilizing SAMDI Technology 2017 ·SLAS DISCOVERY ·Erica C. VanderPorten,Michael D. Scholle,John Sherrill,John C. Tran,Yichin Liu	15
6	Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors 2016 ·Bioorganic & Medicinal Chemistry Letters ·Sharada S. Labadie,Peter S. Dragovich,Richard Cummings,Gauri Deshmukh,Amy Gustafson,Ning Han,Jean-Christophe Harmange,James R. Kiefer,Yue Li,Jun Liang,Bianca M. Liederer,Yichin Liu,Wanda Manieri,(unknown),Lesley Murray,Daniel F. Ortwine,Patrick Trojer,Erica C. VanderPorten,Maia Vinogradova,Li Wen	17
7	Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N -(1 H -Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) 2015 ·Journal of Medicinal Chemistry ·Snahel Patel,Seth F. Harris,Paul Gibbons,Gauri Deshmukh,Amy Gustafson,(unknown),Han Lin,Xingrong Liu,Yanzhou Liu,Yichin Liu,(unknown),Kimberly Scearce‐Levie,Arundhati Sengupta Ghosh,Young G. Shin,Hilda Solanoy,Jian Wang,Bei Wang,Jianping Yin,Michael Siu,Joseph W. Lewcock	45
8	Identification of 12/15-Lipoxygenase as a Regulator of Axon Degeneration through High-Content Screening 2015 ·Journal of Neuroscience ·York Rudhard,Arundhati Sengupta Ghosh,(unknown),Alexander Böcker,(unknown),(unknown),Hai Ngu,Oded Foreman,Yichin Liu,Joseph W. Lewcock	12
9	Small-Molecule Library Subset Screening as an Aid for Accelerating Lead Identification 2014 ·SLAS DISCOVERY ·Maureen H. Beresini,Yichin Liu,(unknown),Kevin Clark,(unknown),(unknown),(unknown),Steven W. Jones,(unknown),(unknown),(unknown),Daniel P. Gross,Nicholas J. Skelton	12
10	Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors 2014 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Jason D. Burch,Steven Magnuson,Daniel F. Ortwine,Yuan Chen,(unknown),Xiao Ding,Charles Eigenbrot,Adam R. Johnson,Marya Liimatta,Yichin Liu,Steven Shia,Xiaolu Wang,Lawren C. Wu,Zhonghua Pei	13
11	Molecular Mechanisms of Alzheimer Disease Protection by the A673T Allele of Amyloid Precursor Protein 2014 ·Journal of Biological Chemistry ·Janice Maloney,Travis W. Bainbridge,Amy Gustafson,Shuo Zhang,(unknown),Pascal Steiner,Marcel van der Brug,Yichin Liu,James A. Ernst,Ryan J. Watts,Jasvinder K. Atwal	142
12	Allosteric inhibition of BACE1 by an exosite-binding antibody 2013 ·Current Opinion in Structural Biology ·Weiru Wang,Yichin Liu,Robert A. Lazarus	29
13	Assessment of the Integrity of Compounds Stored in Assay-Ready Plates Using a Kinase Sentinel Assay 2013 ·Combinatorial Chemistry & High Throughput Screening ·Ada Chen,Xiaoning Zhao,Laina D. Mercer,(unknown),Leeanne Zalameda,Yichin Liu,(unknown),(unknown),(unknown),(unknown),Xiaoyang Xia,Stephen Young,Shou-Hua Xiao,John D. McCarter	2
14	Label-free high-throughput assays to screen and characterize novel lactate dehydrogenase inhibitors 2013 ·Analytical Biochemistry ·Erica C. VanderPorten,Lauren E. Frick,(unknown),(unknown),William A. LaMarr,Yichin Liu	20
15	Discovery of Selective LRRK2 Inhibitors Guided by Computational Analysis and Molecular Modeling 2012 ·Journal of Medicinal Chemistry ·Huifen Chen,Bryan Chan,Jason Drummond,Anthony A. Estrada,Janet Gunzner-Toste,Xingrong Liu,Yichin Liu,John G. Moffat,Daniel G. Shore,Zachary K. Sweeney,Thuy Tran,Shumei Wang,Gui‐Ling Zhao,Haitao Zhu,Daniel J. Burdick	60
16	Case Studies of Minimizing Nonspecific Inhibitors in HTS Campaigns That Use Assay-Ready Plates 2011 ·SLAS DISCOVERY ·Yichin Liu,Maureen H. Beresini,Adam R. Johnson,Robert A. Mintzer,(unknown),Kevin Clark,(unknown),Cristina Lewis,Marya Liimatta,Linda O. Elliott,Amy Gustafson,Christopher E. Heise	7
17	High-throughput assays for sirtuin enzymes: A microfluidic mobility shift assay and a bioluminescence assay 2008 ·Analytical Biochemistry ·Yichin Liu,(unknown),John Y. Wu,Trace S. Tsuruda,John D. McCarter	44
18	Discovery of Acetyl-Coenzyme A Carboxylase 2 Inhibitors: Comparison of a Fluorescence Intensity-Based Phosphate Assay and a Fluorescence Polarization-Based ADP Assay for High-Throughput Screening 2007 ·Assay and Drug Development Technologies ·Yichin Liu,Leeanne Zalameda,Ki Won Kim,Minghan Wang,John D. McCarter	15
19	Discovery of Inhibitors that Elucidate the Role of UCH-L1 Activity in the H1299 Lung Cancer Cell Line 2003 ·Chemistry & Biology ·Yichin Liu,Hilal A. Lashuel,Sung‐Woon Choi,Xuechao Xing,April Case,Jake Ni,Li-An Yeh,Gregory D. Cuny,Ross L. Stein,Peter T. Lansbury	220
20	The UCH-L1 Gene Encodes Two Opposing Enzymatic Activities that Affect α-Synuclein Degradation and Parkinson's Disease Susceptibilitybreakdown → 2002 ·Cell ·Yichin Liu,Lara Fallon,Hilal A. Lashuel,Zhihua Liu,Peter T. Lansbury	652

About Yichin Liu

Yichin Liu is a scholar working on Biological Psychiatry, Geriatrics and Gerontology and Oncology, having authored 33 papers that have together received 2.3k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (6 papers), Mass Spectrometry Techniques and Applications (5 papers) and HER2/EGFR in Cancer Research (4 papers). The work is most often cited by research in Biological Psychiatry (120 citations), Neurology (359 citations) and Molecular Biology (1.3k citations). Yichin Liu has collaborated with scholars based in United States, France and United Kingdom. Frequent co-authors include Peter T. Lansbury, Hilal A. Lashuel, Zhihua Liu, Lara Fallon, John D. McCarter, Ryan J. Watts, Weiru Wang, Jasvinder K. Atwal, Xuechao Xing and Gregory D. Cuny. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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