Cristina Lewis

3.1k citations

26 papers · 1.4k indexed · 1 hit paper · h-index 16

Hepatology top 5%
- Hepatitis C virus research 5
Molecular Biology top 10%
- Biochemical and Molecular Research 6
- Signaling Pathways in Disease 4
Oncology top 10%
- Cancer-related Molecular Pathways 5
- Peptidase Inhibition and Analysis 3
Cell Biology top 10%
- Microtubule and mitosis dynamics 3
Infectious Diseases top 10%
- HIV/AIDS drug development and treatment 5
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 3

Co-authors: Hans E. Parge Laura A. Pelletier J. Ernest Villafranca Richard E. Showalter Vincent J. Kalish Daniel R. Knighton Charles R. Kissinger Kathleen D. Tucker
Cited by: Hepatology Molecular Biology Oncology
Partner nations: United States United Kingdom France

In The Last Decade

Cristina Lewis

26 papers receiving 1.4k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

1995 Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complex

Peers

Countries citing papers authored by Cristina Lewis

Since Specialization

Citations

This map shows the geographic impact of Cristina Lewis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cristina Lewis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cristina Lewis more than expected).

Fields of papers citing papers by Cristina Lewis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cristina Lewis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cristina Lewis. The network helps show where Cristina Lewis may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Cristina Lewis, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Cristina Lewis Line = papers co-authored together Cristina Lewis links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR Timothy P. Heffron,Chudi Ndubaku,Laurent Salphati,Bruno Alicke,Jonathan Cheong,Joy Drobnick,Kyle A. Edgar,Stephen E. Gould,Leslie B. Lee,John Lesnick,Cristina Lewis,Jim Nonomiya,Jodie Pang,Emile G. Plise,Steve Sideris,Jeffrey J. Wallin,Lan Wang,Xiaolin Zhang,Alan G. Olivero	2016	76
2	Identification of GNE-293, a potent and selective PI3Kδ inhibitor: Navigating in vitro genotoxicity while improving potency and selectivity Brian S. Safina,Zachary K. Sweeney,Jun Li,Bryan Chan,Angelina Bisconte,Diane E. Carrera,Georgette M. Castanedo,Michael Flagella,Robert A. Heald,Cristina Lewis,Jeremy Murray,Jim Nonomiya,Jodie Pang,Steve Price,Karin Reif,Laurent Salphati,Eileen M. Seward,BinQing Wei,Daniel P. Sutherlin	2013	25
3	Cis-Amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase Steven T. Staben,Nicole Blaquière,Vickie Tsui,Aleksandr Kolesnikov,Steven Do,Erin K. Bradley,Jenna Dotson,Richard Goldsmith,Timothy P. Heffron,John Lesnick,Cristina Lewis,Jeremy Murray,Jim Nonomiya,Alan G. Olivero,Jodie Pang,Lionel Rougé,Laurent Salphati,BinQing Wei,Christian Wiesmann,Ping Wu	2012	5
4	Case Studies of Minimizing Nonspecific Inhibitors in HTS Campaigns That Use Assay-Ready Plates Yichin Liu,Maureen H. Beresini,Adam R. Johnson,Robert A. Mintzer,Kinjalkumar Shah,Kevin Clark,Stephen Schmidt,Cristina Lewis,Marya Liimatta,Linda O. Elliott,Amy Gustafson,Christopher E. Heise	2011	7
5	Discovery of (R)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor Hui Li,John Tatlock,Angelica Linton,Javier González,Tanya Jewell,Leena Patel,Sarah Ludlum,Matthew Drowns,Sadayappan V. Rahavendran,Heather Skor,R. Hunter,Stephanie T. Shi,Koleen J. Herlihy,Hans E. Parge,Michael J. Hickey,Xiu Yu,Fannie Chau,Jim Nonomiya,Cristina Lewis	2009	93
6	Structure of the Catalytic Domain of Human Polo-like Kinase 1^, Michael Kothe,Darcy Kohls,Simon Low,Rocco Coli,Alan C. Cheng,Suzanne L. Jacques,Theresa Johnson,Cristina Lewis,Christine Loh,Jim Nonomiya,Alissa L. Sheils,Kimberly A. Verdries,Thomas A. Wynn,Cyrille Kuhn,Yuanhua Ding	2007	104
7	Clinical poly(ADP-ribose) polymerase inhibitors for the treatment of cancer. Cristina Lewis,Jennifer A. Low	2007	14
8	Peripheral white blood cell toxicity induced by broad spectrum cyclin‐dependent kinase inhibitors Bart Jessen,Leo Tsz On Lee,Tatiana Koudriakova,Morgan Haines,Karen Lundgren,Sharon Price,Jim Nonomiya,Cristina Lewis,Gregory J. Stevens	2007	37
9	In Vitro Resistance Study of AG-021541, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase Stephanie T. Shi,Koleen J. Herlihy,Joanne P. Graham,Shella A. Fuhrman,Chau Doan,Hans E. Parge,Michael J. Hickey,Jingjin Gao,Xiu Yu,Fannie Chau,Luis Javier González,Hui Li,Cristina Lewis,Amy K. Patick,Rohit Duggal	2007	39
10	Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors Hui Li,John Tatlock,Angelica Linton,Luis Javier González,Allen Borchardt,Peter S. Dragovich,Tanya Jewell,Tom Prins,Ru Zhou,Julie Blazel,Hans E. Parge,Robert A. Love,Michael J. Hickey,Chau Doan,Stephanie T. Shi,Rohit Duggal,Cristina Lewis,Shella A. Fuhrman	2006	44
11	AG-024322 is a potent and selective multi-targeted CDK inhibitor with broad spectrum anti-proliferative activity Cathy C. Zhang,Susan E. Kephart,Indrawan McAlpine,Jim Nonomiya,Joseph R. Higgins,Maria E. Arango,Zhengming Yan,Daniel Knighton,Rose Ann Ferre,Jayashree Tikhe,Gennady M. Verkhivker,Meirong Xu,William H. Romines,Cindy Palmer,Julie Park,Siegfried Reich,Wes Chong,Lin Li,Gerrit Los,Cristina Lewis	2005	8
12	Discovering Novel Anticancer Drugs Practical Aspects and Recent Advances Cristina Lewis,Patrick M. O’Connor	2003	1
13	Structure-Based Design of Novel, Urea-Containing FKBP12 Inhibitors Peter S. Dragovich,John E. Barker,J. V. FRENCH,Michael Imbacuan,Vincent J. Kalish,Charles R. Kissinger,Daniel R. Knighton,Cristina Lewis,Ellen W. Moomaw,Hans E. Parge,Laura A. Pelletier,Thomas J. Prins,Richard E. Showalter,John H. Tatlock,Kathleen D. Tucker,J. Ernest Villafranca	1996	49
14	Design, synthesis and X-ray crystallographic studies of [7.3.1] and [8.3.1] macrocyclic FKBP-12 ligands Robert E. Babine,Ted M. Bleckman,Ethel S. Littlefield,Hans E. Parge,Laura A. Pelletier,Cristina Lewis,J. V. FRENCH,Michael Imbacuan,Susumo Katoh,John H. Tatlock,Richard E. Showalter,J. Ernest Villafranca	1996	8
15	ChemInform Abstract: High‐Affinity FKBP‐12 Ligands Derived from (R)‐(‐)‐Carvone. Synthesis and Evaluation of FK506 Pyranose Ring Replacements. John H. Tatlock,Vincent J. Kalish,Hans E. Parge,Daniel R. Knighton,Richard E. Showalter,Cristina Lewis,J. V. FRENCH,J. Ernest Villafranca	1996	1
16	Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complexbreakdown → Charles R. Kissinger,Hans E. Parge,Daniel R. Knighton,Cristina Lewis,Laura A. Pelletier,Anna Tempczyk,Vincent J. Kalish,Kathleen D. Tucker,Richard E. Showalter,Ellen W. Moomaw,Louis N. Gastinel,Noriyuki Habuka,Xinghai Chen,Fausto Maldonado,John E. Barker,Russell J. Bacquet,J. Ernest Villafranca	1995	630
17	Investigation of Medium Effects in a Family of Decarboxylase Antibodies Theodore M. Tarasow,Cristina Lewis,Donald Hilvert	1994	18
18	Medium Effects in Antibody-Catalyzed Reactions Cristina Lewis,Thomas H. Kramer,Suzanne Robinson,Donald Hilvert	1991	54
19	Formation of an intramolecular cystine disulfide during the reaction of 8-azidoguanosine 5'-triphosphate with cytosolic phosphoenolpyruvate carboxykinase (GTP) causes inactivation without photolabeling Cristina Lewis,Boyd E. Haley,Gerald M. Carlson	1989	23
20	Cysteine 288: An essential hyperreactive thiol of cytosolic phosphoenolpyruvate carboxykinase (GTP) Cristina Lewis,Jerome M. Seyer,G M Carlson	1989	51

About Cristina Lewis

Cristina Lewis is a scholar working on Hepatology, Oncology and Cell Biology, having authored 26 papers that have together received 1.4k indexed citations. Recurring topics across this work include Biochemical and Molecular Research (6 papers), Cancer-related Molecular Pathways (5 papers), Hepatitis C virus research (5 papers), HIV/AIDS drug development and treatment (5 papers), Signaling Pathways in Disease (4 papers), Microtubule and mitosis dynamics (3 papers), Peptidase Inhibition and Analysis (3 papers) and Monoclonal and Polyclonal Antibodies Research (3 papers). The work is most often cited by research in Hepatology (190 citations), Molecular Biology (935 citations) and Oncology (319 citations). Cristina Lewis has collaborated with scholars based in United States, United Kingdom and France. Frequent co-authors include Hans E. Parge, Laura A. Pelletier, J. Ernest Villafranca, Richard E. Showalter, Vincent J. Kalish, Daniel R. Knighton, Charles R. Kissinger, Kathleen D. Tucker, Ellen W. Moomaw and Noriyuki Habuka.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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