Charles Eigenbrot

16.2k total citations · 2 hit papers
120 papers, 8.4k citations indexed

About

Charles Eigenbrot is a scholar working on Molecular Biology, Radiology, Nuclear Medicine and Imaging and Organic Chemistry. According to data from OpenAlex, Charles Eigenbrot has authored 120 papers receiving a total of 8.4k indexed citations (citations by other indexed papers that have themselves been cited), including 56 papers in Molecular Biology, 40 papers in Radiology, Nuclear Medicine and Imaging and 30 papers in Organic Chemistry. Recurrent topics in Charles Eigenbrot's work include Monoclonal and Polyclonal Antibodies Research (37 papers), Glycosylation and Glycoproteins Research (19 papers) and Blood Coagulation and Thrombosis Mechanisms (14 papers). Charles Eigenbrot is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (37 papers), Glycosylation and Glycoproteins Research (19 papers) and Blood Coagulation and Thrombosis Mechanisms (14 papers). Charles Eigenbrot collaborates with scholars based in United States, France and Germany. Charles Eigenbrot's co-authors include Mark X. Sliwkowski, Jennifer L. Stamos, Kenneth N. Raymond, Mark Ultsch, Daniel Kirchhofer, Germaine Fuh, M. Randal, Robert A. Lazarus, Anthony A. Kossiakoff and W. Robert Scheidt and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Charles Eigenbrot

120 papers receiving 8.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor

2002 1.2k citations Charles Eigenbrot et al. Journal of Biological Chemistry profile →
An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

2003 669 citations Charles Eigenbrot et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Charles Eigenbrot United States	46	4.1k	2.4k	2.3k	1.6k	900	120	8.4k
Felix Kratz Germany	51	5.0k 1.2×	1.3k 0.5×	2.7k 1.2×	1.8k 1.1×	359 0.4×	137	10.3k
Iduna Fichtner Germany	49	3.9k 1.0×	808 0.3×	2.9k 1.2×	930 0.6×	964 1.1×	242	8.1k
Lloyd R. Kèlland United Kingdom	57	8.1k 2.0×	800 0.3×	7.0k 3.0×	4.3k 2.6×	460 0.5×	176	15.3k
John A. Hartley United Kingdom	58	7.2k 1.8×	786 0.3×	4.0k 1.7×	3.3k 2.0×	349 0.4×	293	10.9k
Beverly A. Teicher United States	67	8.7k 2.1×	2.0k 0.8×	7.5k 3.2×	946 0.6×	1.8k 2.0×	396	18.1k
Claude F. Meares United States	53	3.4k 0.8×	4.5k 1.8×	1.9k 0.8×	1.0k 0.6×	279 0.3×	220	8.6k
Richard A. Miller United States	41	1.9k 0.5×	630 0.3×	1.3k 0.6×	452 0.3×	1.4k 1.5×	131	5.8k
David A. Boothman United States	67	7.8k 1.9×	881 0.4×	3.6k 1.5×	2.2k 1.4×	910 1.0×	194	13.8k
Umar Mahmood United States	49	3.9k 1.0×	3.3k 1.4×	2.5k 1.1×	367 0.2×	1.4k 1.5×	215	12.5k
David F. Stern United States	64	7.6k 1.9×	2.9k 1.2×	5.8k 2.5×	453 0.3×	1.0k 1.2×	140	12.6k

Countries citing papers authored by Charles Eigenbrot

Since Specialization

Citations

This map shows the geographic impact of Charles Eigenbrot's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles Eigenbrot with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles Eigenbrot more than expected).

Fields of papers citing papers by Charles Eigenbrot

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles Eigenbrot. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles Eigenbrot. The network helps show where Charles Eigenbrot may publish in the future.

Co-authorship network of co-authors of Charles Eigenbrot

This figure shows the co-authorship network connecting the top 25 collaborators of Charles Eigenbrot. A scholar is included among the top collaborators of Charles Eigenbrot based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Charles Eigenbrot. Charles Eigenbrot is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Maun, Henry R., Rajesh Vij, Benjamin T. Walters, et al.. (2020). Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge. Nature Communications. 11(1). 6435–6435. 38 indexed citations

Ultsch, Mark, Wenyan Li, Charles Eigenbrot, et al.. (2019). Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain. Journal of Molecular Biology. 431(5). 885–903. 9 indexed citations

Ultsch, Mark, Bing Li, Till Maurer, et al.. (2016). Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin. Scientific Reports. 6(1). 39374–39374. 90 indexed citations

Ciferri, Claudio, Michael T. Lipari, Wei‐Ching Liang, et al.. (2015). The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody. Biochemical Journal. 472(2). 169–181. 16 indexed citations

Landgraf, Kyle E., Micah Steffek, Clifford Quan, et al.. (2014). An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides. Nature Chemical Biology. 10(7). 567–573. 20 indexed citations

Zhang, Yingnan, Charles Eigenbrot, Lijuan Zhou, et al.. (2013). Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor. Journal of Biological Chemistry. 289(2). 942–955. 127 indexed citations

Eigenbrot, Charles & Germaine Fuh. (2013). Two-in-One antibodies with dual action Fabs. Current Opinion in Chemical Biology. 17(3). 400–405. 31 indexed citations

Eigenbrot, Charles, Rajkumar Ganesan, & Daniel Kirchhofer. (2010). Hepatocyte growth factor activator (HGFA): molecular structure and interactions with HGFA inhibitor‐1 (HAI‐1). FEBS Journal. 277(10). 2215–2222. 19 indexed citations

Fisher, Robert D., Mark Ultsch, Andreas Lingel, et al.. (2010). Structure of the Complex between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine. Journal of Molecular Biology. 402(1). 217–229. 43 indexed citations

10.

Eigenbrot, Charles, Mark Ultsch, Anatoly Dubnovitsky, Lars Abrahmsén, & Torleif Härd. (2010). Structural basis for high-affinity HER2 receptor binding by an engineered protein. Proceedings of the National Academy of Sciences. 107(34). 15039–15044. 170 indexed citations

11.

Olivero, Alan G., Charles Eigenbrot, Richard Goldsmith, et al.. (2005). A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo. Journal of Biological Chemistry. 280(10). 9160–9169. 36 indexed citations

12.

Maun, Henry R., Charles Eigenbrot, & Robert A. Lazarus. (2003). Engineering Exosite Peptides for Complete Inhibition of Factor VIIa Using a Protease Switch with Substrate Phage. Journal of Biological Chemistry. 278(24). 21823–21830. 28 indexed citations

13.

Eigenbrot, Charles, Y. Gloria Meng, Michael T. Lipari, et al.. (2003). Structural Insight into How An Anti-idiotypic Antibody Against D3H44 (Anti-tissue Factor Antibody) Restores Normal Coagulation. Journal of Molecular Biology. 331(2). 433–446. 8 indexed citations

14.

Dennis, Mark S., Charles Eigenbrot, Nicholas J. Skelton, et al.. (2000). Peptide exosite inhibitors of factor VIIa as anticoagulants. Nature. 404(6777). 465–470. 164 indexed citations

15.

Eigenbrot, Charles, et al.. (1994). X‐ray structures of fragments from binding and nonbinding versions of a humanized anti‐CD18 antibody: Structural indications of the key role of V_H residues 59 to 65. Proteins Structure Function and Bioinformatics. 18(1). 49–62. 51 indexed citations

16.

Eigenbrot, Charles, et al.. (1993). X-ray Structures of the Antigen-binding Domains from Three Variants of Humanized anti-p185HER2 Antibody 4D5 and Comparison with Molecular Modeling. Journal of Molecular Biology. 229(4). 969–995. 156 indexed citations

17.

Kelley, Robert F., Mark P. O'Connell, Paul Carter, et al.. (1992). Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments. Biochemistry. 31(24). 5434–5441. 79 indexed citations

18.

Kossiakoff, Anthony A., Mark Ultsch, Steven R. White, & Charles Eigenbrot. (1991). Neutron structure of subtilisin BPN': effects of chemical environment on hydrogen-bonding geometries and the pattern of hydrogen-deuterium exchange in secondary structure elements. Biochemistry. 30(5). 1211–1221. 16 indexed citations

19.

Bell, William L., Calvin J. Curtis, A. Miedaner, et al.. (1988). Manganese tricarbonyl and methylmolybdenum tricarbonyl derivatives of the as-indacene bridging ligand. Organometallics. 7(3). 691–695. 23 indexed citations

20.

Eigenbrot, Charles & Kenneth N. Raymond. (1982). Organouranium complexes of pyrazole and pyrazolate. Synthesis and x-ray structures of U(C 5 Me 5 ) 2 Cl 2 (C 3 H 4 N 2 ), U(C 5 Me 5 ) 2 Cl(C 3 H 4 N 2 ), and U(C 5 Me 5 )(C 3 H 3 N 2 ) 2. Inorganic Chemistry. 21(7). 2653–2660. 61 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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