Yuzhong Deng

2.5k citations

58 papers · 1.9k indexed · h-index 25

Spectroscopy top 1%
- Mass Spectrometry Techniques and Applications 13
- Analytical Chemistry and Chromatography 11
Genetics top 10%
Molecular Biology top 10%
- PI3K/AKT/mTOR signaling in cancer 6
- Melanoma and MAPK Pathways 6
- Protein Structure and Dynamics 5
Analytical Chemistry top 5%
Cancer Research
Oncology
- Drug Transport and Resistance Mechanisms 6
Biomedical Engineering
- Microfluidic and Capillary Electrophoresis Applications 6
Pharmacology
- Pharmacogenetics and Drug Metabolism 5

Co-authors: David L. Smith Zhongqi Zhang Jack D. Henion Steve E. Unger Jing‐Tao Wu Hang Zeng Hai Pan Hongwei Zhang
Cited by: Spectroscopy Genetics Molecular Biology
Journals: Proceedings of the National Academy of Sciences (1 paper)Journal of the American Chemical Society (1 paper)Bioinformatics (1 paper)
Partner nations: United States Germany France

In The Last Decade

Yuzhong Deng

57 papers receiving 1.9k citations

Peers

Countries citing papers authored by Yuzhong Deng

Since Specialization

Citations

This map shows the geographic impact of Yuzhong Deng's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yuzhong Deng with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yuzhong Deng more than expected).

Fields of papers citing papers by Yuzhong Deng

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yuzhong Deng. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yuzhong Deng. The network helps show where Yuzhong Deng may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Yuzhong Deng, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Yuzhong Deng Line = papers co-authored together Yuzhong Deng links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Machine learning-assisted identification of new psychoactive substances in biological sample using miniaturized ambient mass spectrometer Microchemical Journal ·Hang Su,Danxia Yu,Yuzhong Deng,Hongping Zeng,Anqi Chen,Shundi Hu,Miaoxiu Ge,Xiangyu Wang,Wei Xiong,Jiabin Jin,Luhong Wen	2025	0
2	GraphCpG: imputation of single-cell methylomes based on locus-aware neighboring subgraphs Bioinformatics ·Yuzhong Deng,Jianxiong Tang,Jiyang Zhang,Jianxiao Zou,Que Zhu,Shicai Fan	2023	5
3	The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor Drug Metabolism and Disposition ·Ryan Takahashi,Vikram Malhi,Bianca M. Liederer,Sungjoon Cho,Yuzhong Deng,Brian Dean,James Nugteren,Edward Yost,Mohammad H. Al‐Sayah,Rucha Sane,Smita Kshirsagar,Shuguang Ma,Luna Musib	2023	4
4	Single- and multiple-dose pharmacokinetics, potential for CYP3A inhibition, and food effect in patients with cancer and healthy subjects receiving ipatasertib Cancer Chemotherapy and Pharmacology ·Vikram Malhi,Nageshwar Budha,Rucha Sane,Jian Huang,Bianca M. Liederer,Raymond D. Meng,Premal H. Patel,Yuzhong Deng,Andrés Cervantes,Josep Tabernero,Luna Musib	2021	4
5	Catalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug Conjugates Drug Metabolism and Disposition ·Donglu Zhang,Aimee Fourie-O’Donohue,Peter S. Dragovich,Thomas H. Pillow,Jack Sadowsky,Katherine R. Kozak,Robert Cass,Liling Liu,Yuzhong Deng,Yichin Liu,Cornelis E. C. A. Hop,S. Cyrus Khojasteh	2019	36
6	Practical strategies when using a stable isotope labeled microtracer for absolute bioavailability assessment: A case study of a high oral dose clinical candidate GDC-0810 Journal of Pharmaceutical and Biomedical Analysis ·Buyun Chen,Pingping Lu,Dugan Freeman,Yang Gao,Edna F. Choo,Kevin DeMent,Scott Savage,Kelly Zhang,Dennis Milanwoski,Lichuan Liu,Brian Dean,Yuzhong Deng	2018	2
7	Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties Bioorganic & Medicinal Chemistry Letters ·Olivier René,Benjamin P. Fauber,Adrian Barnard,Kerry L. Chapman,Yuzhong Deng,Céline Eidenschenk,Christine Everett,Alberto Gobbi,Adam R. Johnson,Hank La,Maxine Norman,Gary Salmon,Susan Summerhill,Harvey Wong	2016	9
8	Absorption, metabolism and excretion of cobimetinib, an oral MEK inhibitor, in rats and dogs Xenobiotica ·Ryan Takahashi,Shuguang Ma,Qin Yue,Heasook Kim‐Kang,Yijun Yi,Justin Q. Ly,Jason Boggs,Alec Fettes,Andrew McClory,Yuzhong Deng,Cornelis E. C. A. Hop,S. Cyrus Khojasteh,Edna F. Choo	2016	7
9	Reduction in lipophilicity improved the solubility, plasma–protein binding, and permeability of tertiary sulfonamide RORc inverse agonists Bioorganic & Medicinal Chemistry Letters ·Benjamin P. Fauber,Olivier René,Gladys de Leon Boenig,Brenda Burton,Yuzhong Deng,Céline Eidenschenk,Christine Everett,Alberto Gobbi,S.G. Hymowitz,Adam R. Johnson,Hank La,Marya Liimatta,Peter Lockey,Maxine Norman,Wenjun Ouyang,Weiru Wang,Harvey Wong	2014	39
10	In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound The AAPS Journal ·Po‐Chang Chiang,Yong Cui,Yingqing Ran,Joe Lubach,Kang-Jye Chou,Linda Bao,Jia Wei,Hank La,Jonathan Hau,Amy Sambrone,Ann Qin,Yuzhong Deng,Harvey Wong	2013	28
11	Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation Neuro-Oncology ·Sichen Li,Arthur P. Chou,Weidong Chen,Ruihuan Chen,Yuzhong Deng,Heidi Phillips,Julia M. Selfridge,Mira Zurayk,Jerry J. Lou,Richard G. Everson,Kuan-Chung Wu,Kym F. Faull,Timothy F. Cloughesy,Linda M. Liau,Albert Lai	2012	127
12	Novel Nanoparticles Formulation for Cassette Dosing via Intravenous Injection in Rats for High Throughput Pharmacokinetic Screening and Potential Applications Journal of Nanoscience and Nanotechnology ·Po‐Chang Chiang,Yuzhong Deng,Savita Ubhayaka,Hank La,Yong Cui,Kang-Jye Chou,Yingqing Ran,Harvey Wong	2012	5
13	Determination of unbound vismodegib (GDC-0449) concentration in human plasma using rapid equilibrium dialysis followed by solid phase extraction and high-performance liquid chromatography coupled to mass spectrometry Journal of Chromatography B ·Yuzhong Deng,Harvey Wong,Richard Graham,Wenbin Liu,Heuy-shin Shen,Yao Shi,Laixin Wang,Min Meng,Vikram Malhi,Xiao Ding,Brian Dean	2011	18
14	A rugged and accurate liquid chromatography–tandem mass spectrometry method for quantitative determination of BMS-790052 in plasma Journal of Chromatography B ·Hao Jiang,Jianing Zeng,Yuzhong Deng,Yuan-Qin Xia,Zheng Ouyang,Mohammed Jemal,Theodora W. Salcedo,Mark E. Arnold	2011	15
15	Interplay of Dissolution, Solubility, and Nonsink Permeation Determines the Oral Absorption of the Hedgehog Pathway Inhibitor GDC-0449 in Dogs: An Investigation Using Preclinical Studies and Physiologically Based Pharmacokinetic Modeling Drug Metabolism and Disposition ·Harvey Wong,Frank‐Peter Theil,Yong Cui,James C. Marsters,S. Cyrus Khojasteh,Laurent Vernillet,Hank La,Xi‐Ling Song,Hong Wang,Eric J. Morinello,Yuzhong Deng,Cornelis E. C. A. Hop	2010	17
16	Development and validation of sensitive and selective LC–MS/MS methods for the determination of BMS-708163, a γ-secretase inhibitor, in plasma and cerebrospinal fluid using deprotonated or formate adduct ions as precursor ions Journal of Chromatography B ·Huidong Gu,Yuzhong Deng,Jian Wang,Anne‐Françoise Aubry,Mark E. Arnold	2010	21
17	Automated Tecan Programming for Bioanalytical Sample Preparation with EZTecan Assay and Drug Development Technologies ·Huidong Gu,Steve E. Unger,Yuzhong Deng	2006	12
18	High‐speed gradient parallel liquid chromatography/tandem mass spectrometry with fully automated sample preparation for bioanalysis: 30 seconds per sample from plasma Rapid Communications in Mass Spectrometry ·Yuzhong Deng,Jingtao Wu,Thomas L. Lloyd,L. Cecilia,Timothy Olah,Steve E. Unger	2002	60
19	Multiple‐sprayer tandem mass spectrometry with parallel high flow extraction and parallel separation for high‐throughput quantitation in biological fluids Rapid Communications in Mass Spectrometry ·Yuzhong Deng,Hang Zeng,Steve E. Unger,Jing‐Tao Wu	2001	12
20	High‐speed liquid chromatography/tandem mass spectrometry using a monolithic column for high‐throughput bioanalysis Rapid Communications in Mass Spectrometry ·Jing‐Tao Wu,Hang Zeng,Yuzhong Deng,Steve E. Unger	2001	61

About Yuzhong Deng

Yuzhong Deng is a scholar working on Spectroscopy, Pharmacology and Oncology, having authored 58 papers that have together received 1.9k indexed citations. Recurring topics across this work include Mass Spectrometry Techniques and Applications (13 papers), Analytical Chemistry and Chromatography (11 papers), PI3K/AKT/mTOR signaling in cancer (6 papers), Melanoma and MAPK Pathways (6 papers), Drug Transport and Resistance Mechanisms (6 papers), Microfluidic and Capillary Electrophoresis Applications (6 papers), Protein Structure and Dynamics (5 papers) and Pharmacogenetics and Drug Metabolism (5 papers). The work is most often cited by research in Spectroscopy (768 citations), Genetics (156 citations) and Molecular Biology (925 citations). Yuzhong Deng has collaborated with scholars based in United States, Germany and France. Frequent co-authors include David L. Smith, Zhongqi Zhang, Jack D. Henion, Steve E. Unger, Jing‐Tao Wu, Hang Zeng, Hai Pan, Hongwei Zhang, Huidong Gu and Jingtao Wu. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Bioinformatics.

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