Tracy O’Connor

4.9k citations

23 papers · 3.2k indexed · 2 hit papers · h-index 14

Impact in

Neurology top 2%
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological diseases and metabolism
Biological Psychiatry top 5%

Papers in ⓘ

Molecular Biology 10
- Prion Diseases and Protein Misfolding 7
Oncology 7
- Cancer Treatment and Pharmacology 3
- HER2/EGFR in Cancer Research 2

Co-authors: Adriano Aguzzi (8 shared papers)Mathias Heikenwälder (5 shared papers)Robert Vassar (4 shared papers)Marc Ringelhan (2 shared papers)Dominik Pfister (1 shared paper)Eli Pikarsky (1 shared paper)Jie Zhao (2 shared papers)Rodney A. Velliquette (2 shared papers)
Journals: Journal of Clinical Oncology (3 papers)PLoS ONE (3 papers)Journal of Neuroscience (2 papers)PLoS Pathogens (2 papers)Clinical Breast Cancer (1 paper)
Partner nations: Switzerland United States Germany

In The Last Decade

Tracy O’Connor

22 papers receiving 3.1k citations

Hit Papers

align trajectories log scale

The immunology of hepatocellular carcinoma 2018 · 755 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2018 Nature Immunology
2010 Nature Reviews Drug Discovery

Peers

Countries citing papers authored by Tracy O’Connor

Since Specialization

Citations

This map shows the geographic impact of Tracy O’Connor's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tracy O’Connor with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tracy O’Connor more than expected).

Fields of papers citing papers by Tracy O’Connor

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tracy O’Connor. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tracy O’Connor. The network helps show where Tracy O’Connor may publish in the future.

Co-authors

The 25 scholars most cited alongside Tracy O’Connor, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tracy O’Connor Line = papers co-authored together Tracy O’Connor links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The immunology of hepatocellular carcinoma Nature Immunology ·Marc Ringelhan, Dominik Pfister, Tracy O’Connor, Eli Pikarsky, Mathias Heikenwälder Hit paper breakdown →	2018	755
2	Protein aggregation diseases: pathogenicity and therapeutic perspectives Nature Reviews Drug Discovery ·Adriano Aguzzi, Tracy O’Connor Hit paper breakdown →	2010	603
3	Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis Neuron ·Tracy O’Connor, Katherine R. Sadleir, Erika Maus, Rodney A. Velliquette, Jie Zhao, Sarah L. Cole, William A. Eimer, Brian D. Hitt, Leslie A. Bembinster, Sven Lammich, Stefan F. Lichtenthaler, Sébastien S. Hébert, Bart De Strooper, Christian Haass, David A. Bennett, Robert Vassar	2008	344
4	β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Levels Become Elevated in Neurons around Amyloid Plaques: Implications for Alzheimer's Disease Pathogenesis Journal of Neuroscience ·Jie Zhao, Yifan Fu, Marina V. Yasvoina, Peizhen Shao, Brian D. Hitt, Tracy O’Connor, Sreemathi Logan, Erika Maus, Martin Citron, R. Stephen Berry, Lester I. Binder, Robert Vassar	2007	316
5	The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis Journal of Neuroinflammation ·Jie Zhao, Tracy O’Connor, Robert Vassar	2011	299
6	Energy Inhibition Elevates β-Secretase Levels and Activity and Is Potentially Amyloidogenic in APP Transgenic Mice: Possible Early Events in Alzheimer's Disease Pathogenesis Journal of Neuroscience ·Rodney A. Velliquette, Tracy O’Connor, Robert Vassar	2005	215
7	The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein Nature ·Tiziana Sonati, Regina Reimann, Jeppe Falsig, Pravas Kumar Baral, Tracy O’Connor, Simone Hornemann, Sine Yaganoglu, Bei Li, U. Herrmann, Barbara Wieland, Mridula Swayampakula, Muhammad Hafizur Rahman, Dipankar Das, Nat N. V. Kav, Roland Riek, Paweł P. Liberski, Michael N.G. James, Adriano Aguzzi	2013	162
8	CCL2-CCR2 Signaling in Disease Pathogenesis Endocrine Metabolic & Immune Disorders - Drug Targets ·Tracy O’Connor, Lubor Borsig, Mathias Heikenwälder	2015	126
9	The direct and indirect roles of HBV in liver cancer: prospective markers for HCC screening and potential therapeutic targets The Journal of Pathology ·Marc Ringelhan, Tracy O’Connor, Ulrike Protzer, Mathias Heikenwälder	2014	103
10	Prion Infections and Anti-PrP Antibodies Trigger Converging Neurotoxic Pathways PLoS Pathogens ·U. Herrmann, Tiziana Sonati, Jeppe Falsig, Regina Reimann, Paolo Dametto, Tracy O’Connor, Bei Li, Agnes Lau, Simone Hornemann, Silvia Sorce, Uli Wagner, Despina Sanoudou, Adriano Aguzzi	2015	74
11	Ablation of Dicer from Murine Schwann Cells Increases Their Proliferation while Blocking Myelination PLoS ONE ·Juliane Bremer, Tracy O’Connor, Cinzia Tiberi, Hubert Rehrauer, Joachim Weis, Adriano Aguzzi	2010	64
12	Outcome of Everolimus-Based Therapy in Hormone-Receptor-Positive Metastatic Breast Cancer Patients After Progression on Palbociclib Breast Cancer Basic and Clinical Research ·Ajay Dhakal, Roby Thomas, Ellis Levine, Adam Brufsky, Kazuaki Takabe, Matthew G. Hanna, Kristopher Attwood, Austin Miller, Thaer Khoury, Amy Early, Saif Soniwala, Tracy O’Connor, Mateusz Opyrchal	2020	27
13	Efficacy of Palbociclib Combinations in Hormone Receptor–Positive Metastatic Breast Cancer Patients After Prior Everolimus Treatment Clinical Breast Cancer ·Ajay Dhakal, Christina Matthews, Ellis Levine, Kilian Salerno, Fan Zhang, Kazuaki Takabe, Amy Early, Stephen B. Edge, Tracy O’Connor, Thaer Khoury, Jessica Young, Mateusz Opyrchal	2018	21
14	Neurodegeneration and Unfolded-Protein Response in Mice Expressing a Membrane-Tethered Flexible Tail of PrP PLoS ONE ·Paolo Dametto, Asvin KK Lakkaraju, Claire Bridel, Lukas Villiger, Tracy O’Connor, U. Herrmann, Paweł Pelczar, Thomas Rülicke, Donal McHugh, Arlind Adili, Adriano Aguzzi	2015	18
15	The role of lymphotoxin signaling in the development of autoimmune pancreatitis and associated secondary extra-pancreatic pathologies Cytokine & Growth Factor Reviews ·Gitta Seleznik, Jessica Zöller, Tracy O’Connor, Rolf Graf, Mathias Heikenwälder	2014	10
16	Lymphotoxin, but Not TNF, Is Required for Prion Invasion of Lymph Nodes PLoS Pathogens ·Tracy O’Connor, Nathalie Frei, J Sponarová, Petra Schwarz, Mathias Heikenwälder, Adriano Aguzzi	2012	9
17	Prions and lymphoid organs: Solved and remaining mysteries Prion ·Tracy O’Connor, Adriano Aguzzi	2013	6
18	ZyFISH: A Simple, Rapid and Reliable Zygosity Assay for Transgenic Mice PLoS ONE ·Donal McHugh, Tracy O’Connor, Juliane Bremer, Adriano Aguzzi	2012	5
19	A phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) in combination with capecitabine for advanced solid tumors (including patients with progressive or recurrent HER2-negative metastatic breast cancer). Journal of Clinical Oncology ·Ellis Levine, Andres Forero, Tracy O’Connor, Ben K. Seon, Manoj A. Jivani, Bonne J. Adams, Charles P. Theuer	2013	3
20	Outcome of palbociclib based therapy in hormone receptor positive metastatic breast cancer patients after treatment with everolimus. Journal of Clinical Oncology ·Ajay Dhakal, Christina Matthews, Fan Zhang, Ellis Levine, Stephen B. Edge, Kilian Salerno, Tracy O’Connor, Amy Early, Thaer Khoury, Kazuaki Takabe, Jessica Young, Mateusz Opyrchal	2017	3

About Tracy O’Connor

Tracy O’Connor is a scholar working on Molecular Biology, Oncology, Physiology, Pulmonary and Respiratory Medicine and Neurology, having authored 23 papers that have together received 3.2k indexed citations. Recurring topics across this work include Prion Diseases and Protein Misfolding (7 papers), Alzheimer's disease research and treatments (5 papers), Advanced Breast Cancer Therapies (4 papers), Cancer Treatment and Pharmacology (3 papers), Neurological diseases and metabolism (3 papers), Trace Elements in Health (3 papers), HER2/EGFR in Cancer Research (2 papers) and Nuclear Receptors and Signaling (2 papers). The work is most often cited by research in Neurology (497 citations), Biological Psychiatry (128 citations), Physiology (1.2k citations), Hepatology (287 citations) and Cancer Research (326 citations). Tracy O’Connor has collaborated with scholars based in Switzerland, United States and Germany. Frequent co-authors include Adriano Aguzzi, Mathias Heikenwälder, Robert Vassar, Marc Ringelhan, Dominik Pfister, Eli Pikarsky, Jie Zhao, Rodney A. Velliquette, Brian D. Hitt and Erika Maus. Their work appears in journals such as Journal of Clinical Oncology, PLoS ONE, Journal of Neuroscience, PLoS Pathogens and Clinical Breast Cancer.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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