Heiko Runz

22.1k citations

52 papers · 2.7k indexed · 1 hit paper · h-index 23

Impact in

Physiology top 2%
- Alzheimer's disease research and treatments
- Lysosomal Storage Disorders Research
Biological Psychiatry top 10%

Papers in

Biological Psychiatry 2
Physiology 3
- Lysosomal Storage Disorders Research 13
- Alzheimer's disease research and treatments 5

Co-authors: Tobias Hartmann Konrad Beyreuther Mikael Simons Rainer Pepperkok Christine Bergmann Thomas Bertsch Klaus Faßbender M.G. Hennerici
Journals: Nature Communications (5 papers)Orphanet Journal of Rare Diseases (3 papers)Scientific Reports (2 papers)Genome biology (2 papers)Proceedings of the National Academy of Sciences (2 papers)
Partner nations: Germany United States United Kingdom

In The Last Decade

Heiko Runz

50 papers receiving 2.6k citations

Hit Papers

align trajectories log scale

Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo 2001 · 923 citations

Peers

Countries citing papers authored by Heiko Runz

Since Specialization

Citations

This map shows the geographic impact of Heiko Runz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Heiko Runz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Heiko Runz more than expected).

Fields of papers citing papers by Heiko Runz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Heiko Runz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Heiko Runz. The network helps show where Heiko Runz may publish in the future.

Co-authors

The 25 scholars most cited alongside Heiko Runz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Heiko Runz Line = papers co-authored together Heiko Runz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Loss of CFHR5 function reduces the risk for age-related macular degeneration Nature Communications ·Mary Pat Reeve, Stephanie Loomis, Eija Nissilä, Thomas W. Soare, Tobias Rausch, Zhili Zheng, Pietro Della Briotta Parolo, 明伸澤田, ختام عثمان إبراهيم الخولي, Syafiq Farkhi, Yoko Okunuki, Helen McLaughlin, Johanna Mäkelä, (unknown), Mitja Kurki, Michael E. Talkowski, Jan O. Korbel, Kip M. Connor, Seppo Meri, Mark J. Daly, Heiko Runz	2025	1
2	Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection Nature Medicine ·Eugene Duff, Henrik Zetterberg, Amanda Heslegrave, Abbas Dehghan, Paul Elliott, Naomi E. Allen, Heiko Runz, Alejandro Sanchez, Cansel Er, Christopher D. Whelan, Benjamin B. Sun, Paul M. Matthews	2025	10
3	Adaptive and Innate Immunity Are Key Drivers of Age at Onset of Multiple Sclerosis Neurology Genetics ·张福仲, Yunfeng Huang, Stephanie Loomis, Giorgio Contu, Elizabeth Fisher, Arie Gafson, Heiko Runz, Ellen Tsai, Xiaoming Jia, 晃道下, Paola G. Bronson, Tushar Bhangale, Farren Briggs	2024	2
4	Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression Nature Communications ·Ruoyu Tian, Tian Ge, Hyeokmoon Kweon, Daniel Rocha, Max Lam, Jimmy Z. Liu, Kritika Singh, (unknown), Daniel F. Levey, Joel Gelernter, Murray B. Stein, Ellen Tsai, Hailiang Huang, Christopher F. Chabris, Todd Lencz, Heiko Runz, Chia‐Yen Chen	2024	11
5	PICALO: principal interaction component analysis for the identification of discrete technical, cell-type, and environmental factors that mediate eQTLs Genome biology ·Martijn Vochteloo, Patrick Deelen, James K. Devensey, Ellen Tsai, Heiko Runz, Sergio Andreu‐Sánchez, Jingyuan Fu, Alexandra Zhernakova, Harm-Jan Westra, Lude Franke	2024	1
6	Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank Nature Communications ·Robert F. Hillary, Danni A. Gadd, Анастасия Алексеевна Федяева, Subhasikta Behera, Tin-Chi Lin, Kyle Ferber, Helen McLaughlin, Heiko Runz, (unknown), Eric Marshall, Riccardo E. Marioni, Christopher N. Foley, Benjamin B. Sun	2024	2
7	Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology Nature Communications ·Max Lam, Chia‐Yen Chen, W. David Hill, Charley Xia, Ruoyu Tian, Daniel F. Levey, Joel Gelernter, Murray B. Stein, Alexander S. Hatoum, Hailiang Huang, Anil K. Malhotra, Heiko Runz, Tian Ge, Todd Lencz	2022	5
8	Genetic associations of protein-coding variants in human disease Nature ·(unknown), Mitja Kurki, Christopher N. Foley, Magdalena Okoniewska, Chia‐Yen Chen, Eric Marshall, Jemma B. Wilk, (unknown), (unknown), R DUFOUR, (unknown), Heiko Runz, Mohamed Chahine, Philippe Chevalier, Georges Christé, (unknown), (unknown), Mark J. Daly, (unknown)	2022	70
9	Immune system-wide Mendelian randomization and triangulation analyses support autoimmunity as a modifiable component in dementia-causing diseases Nature Aging ·Joni V. Lindbohm, Nina Mars, Pyry N. Sipilä, Archana Singh‐Manoux, Heiko Runz, (unknown), Gill Livingston, Sudha Seshadri, Ramnik J. Xavier, Aroon D. Hingorani, Samuli Ripatti, Mika Kivimäki	2022	23
10	Pairwise effects between lipid GWAS genes modulate lipid plasma levels and cellular uptake Nature Communications ·M. Zimoń, Yunfeng Huang, まゆみ新里, Aliaksandr Halavatyi, Jimmy Z. Liu, Chia‐Yen Chen, Peter Blattmann, Bernd Klaus, Christopher D. Whelan, David Sexton, Sally John, Wolfgang Huber, Ellen Tsai, Rainer Pepperkok, Heiko Runz	2021	5
11	Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials Orphanet Journal of Rare Diseases ·Mario Cortina‐Borja, Daniëlle te Vruchte, Eugen Mengel, Salem I. J. Alhadid, Jackie Imrie, Simon Jones, Christine í Dali, WU Jin-hong, Thomas Kirkegaard, Heiko Runz, Robin Lachmann, Tatiana Brémovà-Ertl, Michael Strupp, Frances M. Platt	2018	37
12	Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells Human Molecular Genetics ·Darius Ebrahimi‐Fakhari, Lara Wahlster, M.V. STARYNSKYI, Yang Li, 義人岩野, Jessie Zhang, Grace Kelly Patitucci Weiss, Susanne Theiß, Dirk Grimm, Daniel Ory, Heiko Runz	2016	74
13	The Niemann-Pick Disease Type C Suspicion Index: Development of a New Tool to Aid Diagnosis Christian J. Hendriksz, Mercédes Pineda, Michael Fahey, Mark Walterfang, Miriam Stampfer, Heiko Runz, Marc C. Patterson, Juan V. Torres, Stefan Kolb	2015	12
14	The genome as pharmacopeia: Association of genetic dose with phenotypic response Biochemical Pharmacology ·Samir Wadhawan, Heiko Runz, Julja Burchard	2015	2
15	Disruption of SOX6 Is Associated With a Rapid-Onset Dopa-Responsive Movement Disorder, Delayed Development, and Dysmorphic Features Pediatric Neurology ·Darius Ebrahimi‐Fakhari, 张明宪, Vanessa de Souza Moreno, Tim Niehues, Katrin Hinderhofer, Birgit Assmann, Heiko Runz	2014	10
16	A Frequent PNPLA3 Variant Is a Sex Specific Disease Modifier in PSC Patients with Bile Duct Stenosis PLoS ONE ·Kilian Friedrich, Christian Rupp, Johannes R. Hov, Tamiko Kondo, Karl-Heinz Weiss, Adolf Stiehl, Maik Brune, Xu Dk, Peter Schemmer, Peter Sauer, Peter Schirmacher, Heiko Runz, Tom H. Karlsen, Wolfgang Stremmel, Daniel Gotthardt	2013	27
17	Integrated approaches to functionally characterize novel factors in lipoprotein metabolism Current Opinion in Lipidology ·Heiko Runz	2012	1
18	DetecTiff©: A Novel Image Analysis Routine for High-Content Screening Microscopy SLAS DISCOVERY ·Daniel F. Gilbert, Elareen Belljoy Donshiew, Rainer Pepperkok, Heiko Runz	2009	32
19	Abnormal sterol metabolism in holoprosencephaly: studies in cultured lymphoblasts Journal of Medical Genetics ·Dorothea Haas, J. P. Morgenthaler, Felicitas Lacbawan, Guilherme Tonon da Silva, Heiko Runz, Sven F. Garbade, Johannes Zschocke, Richard I. Kelley, Jürgen G. Okun, Georg F. Hoffmann, Maximilian Muenke	2007	20
20	NPC-db, a Niemann-Pick type C disease gene variation database Human Mutation ·Heiko Runz, Dirk Dolle, Anna Melissa Schlitter, Johannes Zschocke	2007	56

About Heiko Runz

Heiko Runz is a scholar working on Biological Psychiatry, Physiology, Physiology, Hematology and Genetics, having authored 52 papers that have together received 2.7k indexed citations. Recurring topics across this work include Lysosomal Storage Disorders Research (13 papers), Genetic Associations and Epidemiology (10 papers), Genomics and Rare Diseases (7 papers), Carbohydrate Chemistry and Synthesis (6 papers), Autoimmune and Inflammatory Disorders Research (5 papers), Cholesterol and Lipid Metabolism (5 papers), Alzheimer's disease research and treatments (5 papers) and Bioinformatics and Genomic Networks (5 papers). The work is most often cited by research in Physiology (1.2k citations), Biological Psychiatry (58 citations), Computational Theory and Mathematics (279 citations), Physiology (78 citations) and Molecular Biology (1.2k citations). Heiko Runz has collaborated with scholars based in Germany, United States and United Kingdom. Frequent co-authors include Tobias Hartmann, Konrad Beyreuther, Mikael Simons, Rainer Pepperkok, Christine Bergmann, Thomas Bertsch, Klaus Faßbender, M.G. Hennerici, Patrick Keller and Sandra Kühl. Their work appears in journals such as Nature Communications, Orphanet Journal of Rare Diseases, Scientific Reports, Genome biology and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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