David D. Schlaepfer

28.0k total citations · 8 hit papers
136 papers, 22.5k citations indexed

About

David D. Schlaepfer is a scholar working on Immunology and Allergy, Cell Biology and Molecular Biology. According to data from OpenAlex, David D. Schlaepfer has authored 136 papers receiving a total of 22.5k indexed citations (citations by other indexed papers that have themselves been cited), including 102 papers in Immunology and Allergy, 73 papers in Cell Biology and 69 papers in Molecular Biology. Recurrent topics in David D. Schlaepfer's work include Cell Adhesion Molecules Research (102 papers), Cellular Mechanics and Interactions (63 papers) and Protease and Inhibitor Mechanisms (31 papers). David D. Schlaepfer is often cited by papers focused on Cell Adhesion Molecules Research (102 papers), Cellular Mechanics and Interactions (63 papers) and Protease and Inhibitor Mechanisms (31 papers). David D. Schlaepfer collaborates with scholars based in United States, China and Canada. David D. Schlaepfer's co-authors include Satyajit K. Mitra, Tony Hunter, Christof R. Hauck, David J. Sieg, Duško Ilić, Harry T. Haigler, Christine Jean, Steven K. Hanks, Florian J. Sulzmaier and Peter van der Geer and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

David D. Schlaepfer

135 papers receiving 22.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Focal adhesion kinase: in command and control of cell motility

2005 2.0k citations Satyajit K. Mitra, David D. Schlaepfer et al. profile →
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1994 1.4k citations David D. Schlaepfer, Steven K. Hanks et al. profile →
Integrin-regulated FAK–Src signaling in normal and cancer cells

2006 1.3k citations Satyajit K. Mitra, David D. Schlaepfer profile →
FAK integrates growth-factor and integrin signals to promote cell migration

2000 1.1k citations David J. Sieg, Christof R. Hauck et al. profile →
FAK in cancer: mechanistic findings and clinical applications

2014 1.0k citations Florian J. Sulzmaier, Christine Jean et al. profile →
Signaling through focal adhesion kinase

1999 1.0k citations David D. Schlaepfer, Christof R. Hauck et al. Progress in Biophysics and Molecular Biology profile →
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

1999 580 citations David J. Sieg, Christof R. Hauck et al. profile →
Targeting FAK in anticancer combination therapies

2021 254 citations Dwayne G. Stupack, David D. Schlaepfer et al. profile →

Peers

Countries citing papers authored by David D. Schlaepfer

Since Specialization

Citations

This map shows the geographic impact of David D. Schlaepfer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David D. Schlaepfer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David D. Schlaepfer more than expected).

Fields of papers citing papers by David D. Schlaepfer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David D. Schlaepfer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David D. Schlaepfer. The network helps show where David D. Schlaepfer may publish in the future.

Co-authorship network of co-authors of David D. Schlaepfer

This figure shows the co-authorship network connecting the top 25 collaborators of David D. Schlaepfer. A scholar is included among the top collaborators of David D. Schlaepfer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David D. Schlaepfer. David D. Schlaepfer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Nuclear Focal Adhesion Kinase Protects against Cisplatin Stress in Ovarian Carcinoma 2024 ·Cancer Research Communications ·(unknown), (unknown), Antonia Boyer, Xiao Lei Chen, (unknown), (unknown), (unknown), (unknown), (unknown), Douglas B. Flieder, Denise C. Connolly, Alfredo Molinolo, Michael McHale, Dwayne G. Stupack, David D. Schlaepfer	1
2	TGFBI remodels adipose metabolism by regulating the Notch-1 signaling pathway 2023 ·Experimental & Molecular Medicine ·Seul Gi Lee, (unknown), Seon Min Woo, Seung Un Seo, Ha-Jeong Kim, (unknown), David D. Schlaepfer, In‐San Kim, (unknown), Taeg Kyu Kwon, Ju‐Ock Nam	16
3	FAK Inhibition Disrupts a β5 Integrin Signaling Axis Controlling Anchorage-Independent Ovarian Carcinoma Growth 2014 ·Molecular Cancer Therapeutics ·Isabelle Tancioni, Sean Uryu, Florian J. Sulzmaier, Nina R. Shah, Christine Lawson, Nichol Miller, Christine Jean, Xiao Lei Chen, Kristy Ward, David D. Schlaepfer	48
4	RhoGEFs in Cell Motility: Novel Links Between Rgnef and Focal Adhesion Kinase 2014 ·Current Molecular Medicine ·Nichol Miller, Elizabeth G. Kleinschmidt, David D. Schlaepfer	21
5	Integrin adhesions 2012 ·Cell Adhesion & Migration ·Christine Lawson, David D. Schlaepfer	40
6	VEGF-Induced Vascular Permeability Is Mediated by FAK 2012 ·Developmental Cell ·Xiao Lei Chen, Ju‐Ock Nam, Christine Jean, Christine Lawson, Colin Walsh, Erik T. Goka, Ssang‐Taek Lim, Alok Tomar, Isabelle Tancioni, Sean Uryu, Jun‐Lin Guan, Lisette M. Acevedo, Sara M. Weis, David A. Cheresh, David D. Schlaepfer	268
7	p190RhoGEF (Rgnef) Promotes Colon Carcinoma Tumor Progression via Interaction with Focal Adhesion Kinase 2011 ·Cancer Research ·Honggang Yu, Ju‐Ock Nam, Nichol Miller, Isabelle Tanjoni, Colin Walsh, Lei Shi, Linda Kim, Xiao Lei Chen, Alok Tomar, Ssang‐Taek Lim, David D. Schlaepfer	49
8	EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation 2011 ·Oncogene ·Miller Huang, Sudarshan Anand, (unknown), Jay S. Desgrosellier, Dwayne G. Stupack, Sanford J. Shattil, David D. Schlaepfer, David A. Cheresh	57
9	Specific Cross-talk between Epidermal Growth Factor Receptor and Integrin αvβ5 Promotes Carcinoma Cell Invasion and Metastasis 2009 ·Cancer Research ·Jill M. Ricono, Miller Huang, Leo A. Barnes, Steven Lau, Sara M. Weis, David D. Schlaepfer, Steven K. Hanks, David A. Cheresh	116
10	Caspase-8 Association with the Focal Adhesion Complex Promotes Tumor Cell Migration and Metastasis 2009 ·Cancer Research ·Simone Barbero, Ainhoa Mielgo, Vicente A. Torres, Tal Teitz, David J. Shields, David Mikolon, Matthew Bogyo, Daniela Barilá, Jill M. Lahti, David D. Schlaepfer, Dwayne G. Stupack	112
11	FERM control of FAK function: Implications for cancer therapy 2008 ·Cell Cycle ·Ssang‐Taek Lim, David Mikolon, Dwayne G. Stupack, David D. Schlaepfer	108
12	Angiopoietin 2 Induces Glioma Cell Invasion by Stimulating Matrix Metalloprotease 2 Expression through the αvβ1 Integrin and Focal Adhesion Kinase Signaling Pathway 2006 ·Cancer Research ·Bo Hu, Michael J. Jarzynka, Ping Guo, Yorihisa Imanishi, David D. Schlaepfer, Shi‐Yuan Cheng	136
13	Focal adhesion kinase (FAK) activity promotes tumor growth and neo-vascularization via upregulation of angiogenic factors 2005 ·Cancer Research ·Satyajit K. Mitra, John J. Molina, (unknown), Datsun A. Hsia, David Mikolon, (unknown), Dwayne G. Stupack, David A. Cheresh, David D. Schlaepfer	3
14	FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion 2005 ·The Journal of Cell Biology ·Naciba Benlimame, Qiang He, Jie Su, Dingzhang Xiao, Ying Xu, Martin Loignon, David D. Schlaepfer, Moulay A. Alaoui‐Jamali	112
15	Localized Stabilization of Microtubules by Integrin- and FAK-Facilitated Rho Signaling 2004 ·Science ·Alexander F. Palazzo, Christina H. Eng, David D. Schlaepfer, Eugene E. Marcantonio, Gregg G. Gundersen	354
16	Control of motile and invasive cell phenotypes by focal adhesion kinase 2004 ·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·David D. Schlaepfer, Satyajit K. Mitra, Duško Ilić	371
17	Paxillin Binding to the α4 Integrin Subunit Stimulates LFA-1 (Integrin αLβ2)-Dependent T Cell Migration by Augmenting the Activation of Focal Adhesion Kinase/Proline-Rich Tyrosine Kinase-2 2003 ·The Journal of Immunology ·David M. Rose, Shouchun Liu, Darren G. Woodside, Jaewon Han, David D. Schlaepfer, Mark H. Ginsberg	79
18	Direct Interaction of Focal Adhesion Kinase with p190RhoGEF 2003 ·Journal of Biological Chemistry ·Jinbin Zhai, Hong Lin, Zhenying Nie, Junhua Wu, Rafaela Cañete-Soler, William W. Schlaepfer, David D. Schlaepfer	157
19	Signaling through focal adhesion kinase breakdown → 1999 ·Progress in Biophysics and Molecular Biology ·David D. Schlaepfer, Christof R. Hauck, David J. Sieg	1007
20	Fibronectin-Stimulated Signaling from a Focal Adhesion Kinase–c-Src Complex: Involvement of the Grb2, p130 ^cas , and Nck Adaptor Proteins 1997 ·Molecular and Cellular Biology ·David D. Schlaepfer, Martin A. Broome, Tony Hunter	390

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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